The T Cell Costimulator TL1A Is Induced by FcγR Signaling in Human Monocytes and Dendritic Cells

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Immunology

• Publication date

  2007-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.178.7.4033PMID 17371957
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• TL1A: a mediator of gut inflammation.

  2006cited by this paper
• Role of TL1A and its receptor DR3 in two models of chronic murine ileitis.

  2006cited by this paper
• Dominant Role for TL1A/DR3 Pathway in IL-12 plus IL-18-Induced IFN-γ Production by Peripheral Blood and Mucosal CCR9+ T Lymphocytes1

  2005cited by this paper
• Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity.

  2005cited by this paper
• Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease.

  2005cited by this paper
• Identification of naturally secreted soluble form of TL1A, a TNF-like cytokine.

  2005influential reference
• Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells

  2005cited by this paper
• Network of dendritic cells within the muscular layer of the mouse intestine.

  2005cited by this paper
• Attenuation of Th1 Response in Decoy Receptor 3 Transgenic Mice1

  2005influential reference
• TL1A Synergizes with IL-12 and IL-18 to Enhance IFN-γ Production in Human T Cells and NK Cells1

  2004cited by this paper
• Bacterial flagellin is a dominant antigen in Crohn disease.

  2004cited by this paper
• T Cell Biasing by Activated Dendritic Cells1

  2004cited by this paper
• Potential role for TL1A, the new TNF-family member and potent costimulator of IFN-gamma, in mucosal inflammation.

  2004cited by this paper
• Expression, Localization, and Functional Activity of TL1A, a Novel Th1-Polarizing Cytokine in Inflammatory Bowel Disease 1

  2003cited by this paper
• CC Chemokine Receptor 9 Expression Defines a Subset of Peripheral Blood Lymphocytes with Mucosal T Cell Phenotype and Th1 or T-Regulatory 1 Cytokine Profile 1

  2003cited by this paper
• TL1A-induced NF-κB Activation and c-IAP2 Production Prevent DR3-mediated Apoptosis in TF-1 Cells*

  2003cited by this paper
• Inducing Tumor Immunity through the Selective Engagement of Activating Fcγ Receptors on Dendritic Cells

  2002cited by this paper
• TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator.

  2002influential reference
• IgG Fc receptors.

  2001influential reference
• Immune Complex and Fc Receptor-Mediated Augmentation of Antigen Presentation for in Vivo Th Cell Responses1

  2000cited by this paper
• Fcγ Receptor–mediated Induction of Dendritic Cell Maturation and Major Histocompatibility Complex Class I–restricted Antigen Presentation after Immune Complex Internalization

  1999cited by this paper
• Differentiation of human dendritic cells from monocytes in vitro

  1997cited by this paper
• Direct evidence of monocyte recruitment to inflammatory bowel disease mucosa

  1995cited by this paper

• GB20-5A8-31, an anti-TL1A antibody for treating inflammatory bowel disease.

  2026cites this paper
• The Therapeutic Potential of Targeting TL1A in a Spectrum of Inflammatory Disorders

  2026cites this paper
• TL1A: a novel alarmin in airway, intestinal, and autoimmune disorders.

  2025cites this paper
• Gut-Heart Axis: Cardiac Remodeling and Heart Failure in the Context of Inflammatory Bowel Disease and Dysbiosis.

  2025cites this paper
• TL1A as a Target in Inflammatory Bowel Disease: Exploring Mechanisms and Therapeutic Potential

  2025cites this paper
• The role of fat‐soluble vitamins in efferocytosis

  2024cites this paper
• The ever-expanding role of cytokine receptor DR3 in T cells.

  2024cites this paper
• Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis

  2024cites this paper
• The landscape of new therapeutic opportunities for IBD.

  2024cites this paper
• TL1A: A model for a precision medicine approach in the treatment of Crohn's disease and ulcerative colitis.

  2024cites this paper
• Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD

  2024cites this paper
• Progress in research of TNF-like cytokine 1A as a therapeutic target for inflammatory bowel disease

  2024cites this paper
• Inflammation accelerating intestinal fibrosis: from mechanism to clinic

  2024cites this paper
• Lung ILC2s are activated in BALB/c mice born to immunized mothers despite complete protection against respiratory syncytial virus

  2024cites this paper
• Angiogenic and anti‐angiogenic factors during the post‐hatching growth of the quail (Coturnix coturnix japonica) spleen

  2024cites this paper
• TL1A priming induces a multi-cytokine Th9 cell phenotype that promotes robust allergic inflammation in murine models of asthma

  2024cites this paper
• Versatile roles of innate lymphoid cells at the mucosal barrier: from homeostasis to pathological inflammation

  2023cites this paper
• Advances in biological and targeted therapies for systemic sclerosis

  2023cites this paper
• DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier Injury

  2023cites this paper
• Role of TL1A in Inflammatory Autoimmune Diseases: A Comprehensive Review

  2022cites this paper
• Anti-TLR7 Antibody Protects Against Lupus Nephritis in NZBWF1 Mice by Targeting B Cells and Patrolling Monocytes

  2021cites this paper
• Are Fc Gamma Receptor Polymorphisms Important in HIV-1 Infection Outcomes and Latent Reservoir Size?

  2021cites this paper
• Gut microbial transcytosis induced by tumor necrosis factor-like 1A-dependent activation of a myosin light chain kinase splice variant contributes to IBD.

  2020cites this paper
• Circulating TNF-like protein 1A (TL1A) is elevated early in rheumatoid arthritis and depends on TNF

  2020influential citation
• Intraocular tumour necrosis factor ligand related molecule 1 A links disease progression of proliferative diabetic retinopathy after primary vitrectomy

  2020cites this paper
• Cloning and characterization of tumor necrosis factor superfamily 15 in rock bream, Oplegnathus fasciatus; phylogenetic, in silico, and expressional analysis.

  2020cites this paper
• Fenebrutinib Versus Placebo or Adalimumab in Rheumatoid Arthritis: A Randomized, Double‐Blind, Phase II Trial

  2020cites this paper
• IgG and Fcγ Receptors in Intestinal Immunity and Inflammation

  2019cites this paper
• TL1A (TNFSF15) and DR3 (TNFRSF25): A Co-stimulatory System of Cytokines With Diverse Functions in Gut Mucosal Immunity

  2019cites this paper
• Expression profiling of genes in rheumatoid fibroblast-like synoviocytes regulated by tumor necrosis factor-like ligand 1A using cDNA microarray analysis

  2019cites this paper
• Direct signaling of TL1A-DR3 on fibroblasts induces intestinal fibrosis in vivo

  2018cites this paper
• Cytokine and Anti-Cytokine Agents as Future Therapeutics for Fibrostenosing IBD

  2018cites this paper
• Investigating the role of IgG and Fcγ receptors in intestinal inflammation

  2018cites this paper
• Inflammation independent TL1A-mediated Intestinal Fibrosis is Dependent on the Gut Microbiome

  2018cites this paper
• Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn’s Disease-Like Ileitis

  2018cites this paper
• Role of TNFSF15 in the intestinal inflammatory response

  2018cites this paper
• Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease

  2018cites this paper
• Cleavage of TL1A Differentially Regulates Its Effects on Innate and Adaptive Immune Cells

  2018cites this paper
• A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell

  2017cites this paper
• Identification of Novel Proteins Interacting with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma.

  2017cites this paper
• Title The Role of TL 1 A and DR 3 in Autoimmune and Inflammatory Diseases

  2017cites this paper
• Effect of infusion of monoclonal antibodies to tumour necrosis factor‐receptor super family 25 on graft rejection in allo‐immune mice receiving autologous marrow transplantation

  2017cites this paper
• Multifaceted death receptor 3 signaling—promoting survival and triggering death

  2017cites this paper
• The TNF family member TL1A induces IL‐22 secretion in committed human Th17 cells via IL‐9 induction

  2017cites this paper
• T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria

  2017cites this paper
• Activating transcription factor 3 (ATF3) protects against lipopolysaccharide‐induced acute lung injury via inhibiting the expression of TL1A

  2017cites this paper
• Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease.

  2017cites this paper
• Trophic and neurotrophic factors in human pituitary adenomas (Review).

  2017cites this paper
• Identification of Novel Protein Interacts with Vascular Endothelial Growth Inhibitor 174 in Renal Cell Carcinoma

  2017cites this paper
• Sentinels of the Type 2 Immune Response.

  2017cites this paper
• Interpreting Macrophage Transcripts In Human T Cell-Mediated Rejection

  2017cites this paper
• TL1A increased IL-6 production on fibroblast-like synoviocytes by preferentially activating TNF receptor 2 in rheumatoid arthritis.

  2016cites this paper
• A case-control study about the association between vascular endothelial growth inhibitor gene polymorphisms and breast cancer risk in female patients in Northeast China

  2016cites this paper
• Differential Levels of Tl1a Affect the Expansion and Function of Regulatory T Cells in Modulating Murine Colitis

  2016cites this paper
• Cytokine and anti-cytokine therapies in prevention or treatment of fibrosis in IBD

  2016cites this paper
• The TNF Receptor Superfamily in Co-stimulating and Co-inhibitory Responses.

  2016influential citation
• Biologics beyond TNF-α inhibitors and the effect of targeting the homologues TL1A-DR3 pathway in chronic inflammatory disorders

  2016cites this paper
• A Novel Role for TL1A/DR3 in Protection against Intestinal Injury and Infection

  2016cites this paper
• Secretion, blood levels and cutaneous expression of TL1A in psoriasis patients

  2015influential citation
• Group 2 innate lymphoid cells in the regulation of immune responses.

  2015cites this paper
• Human group3 innate lymphoid cells express DR3 and respond to TL1A with enhanced IL‐22 production and IL‐2‐dependent proliferation

  2015cites this paper
• The TL1A/DR3/DcR3 pathway in autoimmune rheumatic diseases.

  2015cites this paper
• Cytokines in inflammatory bowel disease

  2015cites this paper
• Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia

  2015cites this paper
• The TNF‐family cytokine TL1A: from lymphocyte costimulator to disease co‐conspirator

  2015cites this paper
• TL1A as a Potential Local Inducer of IL17A Expression in Colon Mucosa of Inflammatory Bowel Disease Patients

  2015cites this paper
• Tumor Necrosis Factor–like Cytokine TL1A and Its Receptors DR3 and DcR3: Important New Factors in Mucosal Homeostasis and Inflammation

  2015cites this paper
• The role of Death Receptor 3 in allergic lung inflammation

  2014cites this paper
• A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

  2014cites this paper
• Regulation of T cell effector functions in the intestinal mucosa

  2014cites this paper
• Progranulin-Derived Atsttrin Directly Binds to TNFRSF25 (DR3) and Inhibits TNF-Like Ligand 1A (TL1A) Activity

  2014cites this paper
• Immunopathology of inflammatory bowel disease.

  2014cites this paper
• Tumour Necrosis Factor Superfamily Members in the Pathogenesis of Inflammatory Bowel Disease

  2014cites this paper
• Use of animal models in elucidating disease pathogenesis in IBD

  2014cites this paper
• A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8–induced IL-1

  2014cites this paper
• Cytokines in inflammatory bowel disease

  2014cites this paper
• Development and characterization of mouse monoclonal antibodies reactive with chicken TL1A.

  2014cites this paper
• The roles of TL1A and Pno1 in the pathogenesis of rheumatoid arthritis

  2014influential citation
• Immunobiology of TNFSF15 and TNFRSF25

  2013cites this paper
• Decoy receptor 3 regulates the expression of various genes in rheumatoid arthritis synovial fibroblasts.

  2013cites this paper
• Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells.

  2013cites this paper
• The TNF-Family Cytokine TL1A Promotes Allergic Immunopathology through Group 2 Innate Lymphoid Cells

  2013cites this paper
• Suppression of renal cell carcinoma growth in vivo by forced expression of vascular endothelial growth inhibitor.

  2013cites this paper
• The Role of TL1A and DR3 in Autoimmune and Inflammatory Diseases

  2013cites this paper
• The TNF-Family Cytokine TL1A Inhibits Proliferation of Human Activated B Cells

  2013cites this paper
• The tumor necrosis factor-like cytokine 1A/death receptor 3 cytokine system in intestinal inflammation

  2013cites this paper
• The differential expression of vascular endothelial growth inhibitor isoforms, VEGI251, VEGI174 and VEGI192 in human clear-cell renal cell carcinoma.

  2013cites this paper
• Cloning, Expression, and Functional Characterization of TL1A-Ig

  2013cites this paper
• SUSTAINED TL1A (TNFSF15) EXPRESSION ON BOTH LYMPHOID AND MYELOID CELLS LEADS TO MILD SPONTANEOUS INTESTINAL INFLAMMATION AND FIBROSIS.

  2013cites this paper
• Death receptor 3 : a regulator of bone turnover and new target for therapy for osteoporosis?

  2013influential citation
• Seminars in Arthritis and Rheumatism

  2013cites this paper
• The role of Death Receptor 3 in the accumulation of immune cells in inflammatory disease

  2013cites this paper
• Cytokines and Inflammatory Bowel Disease

  2013cites this paper
• Regulating atherosclerosis via costimulatory and coinhibitory pathways

  2013cites this paper
• This information is current as Characterization of TL 1 AIg Cloning , Expression , and Functional

  2013cites this paper
• New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation.

  2012cites this paper
• On death receptor 3 and its ligands…

  2012cites this paper
• Current concepts on the immunopathogenesis of inflammatory bowel disease.

  2012cites this paper
• TNFSF15 Modulates Neovascularization and Inflammation

  2012cites this paper
• Targeting NF-TLR 2-Mediated B Cell Activation by Decoy Receptor 3 Suppresses

  2012cites this paper