Reactive oxygen species regulate activation-induced T cell apoptosis.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Immunity

• Publication date

  1999-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S1074-7613(00)80072-2PMID 10403648
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Mitochondrial control of apoptosis].

  2001cited by this paper
• Molecular characterization of mitochondrial apoptosis-inducing factor

  1999cited by this paper
• Oxidant, mitochondria and calcium: an overview.

  1999cited by this paper
• T cell growth cytokines cause the superinduction of molecules mediating antigen-induced T lymphocyte death.

  1998cited by this paper
• Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.

  1998cited by this paper
• Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis.

  1998cited by this paper
• Inhibition of Neuronal Apoptosis by a Metalloporphyrin Superoxide Dismutase Mimic

  1998cited by this paper
• The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens.

  1998cited by this paper
• Involvement of caspases in neutrophil apoptosis: regulation by reactive oxygen species.

  1998cited by this paper
• A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

  1998cited by this paper
• Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes.

  1998cited by this paper
• The mitochondrial death/life regulator in apoptosis and necrosis.

  1998cited by this paper
• Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors.

  1998cited by this paper
• A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

  1998cited by this paper
• The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition*

  1998cited by this paper
• Need for caspases in apoptosis of trophic factor‐deprived PC12 cells

  1997cited by this paper
• Caspases: the executioners of apoptosis.

  1997cited by this paper
• Ex vivo induction of apoptosis in lymphocytes is mediated by oxidative stress: role for lymphocyte loss in HIV infection.

  1997cited by this paper
• Manganic porphyrins possess catalase activity and protect endothelial cells against hydrogen peroxide-mediated injury.

  1997cited by this paper
• The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock

  1997cited by this paper
• Involvement of caspases in sympathetic neuron apoptosis.

  1997cited by this paper
• Mitochondrial control of apoptosis.

  1997cited by this paper
• ICE-protease inhibitors block murine liver injury and apoptosis caused by CD95 or by TNF-alpha.

  1997cited by this paper
• Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.

  1997cited by this paper
• Inhibition of Ced-3/ICE-related Proteases Does Not Prevent Cell Death Induced by Oncogenes, DNA Damage, or the Bcl-2 Homologue Bak

  1997cited by this paper
• DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis.

  1997cited by this paper
• Human Bak induces cell death in Schizosaccharomyces pombe with morphological changes similar to those with apoptosis in mammalian cells

  1997cited by this paper
• Mechanisms of peripheral T cell deletion: anergized T cells are Fas resistant but undergo proliferation‐associated apoptosis

  1996cited by this paper
• Different Interleukin-1β Converting Enzyme (ICE) Family Protease Requirements for the Apoptotic Death of T Lymphocytes Triggered by Diverse Stimuli

  1996cited by this paper
• The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance.

  1996cited by this paper
• Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c.

  1996cited by this paper
• Fas-induced Activation of the Cell Death-related Protease CPP32 Is Inhibited by Bcl-2 and by ICE Family Protease Inhibitors*

  1996cited by this paper
• BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.

  1996cited by this paper
• Requirement for superoxide in excitotoxic cell death.

  1996cited by this paper
• Induction of apoptosis in mature T cells by tumour necrosis factor

  1995cited by this paper
• Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo

  1995cited by this paper
• Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

  1995cited by this paper
• Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

  1995cited by this paper
• Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

  1995cited by this paper
• Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

  1995cited by this paper
• Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death

  1995cited by this paper
• A metalloporphyrin superoxide dismutase mimetic protects against paraquat-induced endothelial cell injury, in vitro.

  1995cited by this paper
• Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo

  1995cited by this paper
• The molecular mechanism of FasL-mediated cytotoxicity by CD4+ Th1 clones.

  1995cited by this paper
• The mitochondrial permeability transition.

  1995cited by this paper
• Redox regulation of programmed cell death in lymphocytes.

  1995cited by this paper
• In vivo CD4+ lymph node T cells from lpr mice generate CD4-CD8-B220+TCR-beta low cells.

  1994cited by this paper
• The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice.

  1994cited by this paper
• Superantigens and their potential role in human disease.

  1993cited by this paper
• Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice.

  1993cited by this paper
• Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transition.

  1993cited by this paper
• A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

  1992cited by this paper
• lnterleukin-2 programs mouse αβ T lymphocytes for apoptosis

  1991cited by this paper
• Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

  1991cited by this paper
• Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis.

  1991cited by this paper
• Catalysis of the disproportionation of superoxide by metalloporphyrins. III.

  1981cited by this paper
• A rapid method for the isolation of functional thymus‐derived murine lymphocytes

  1973cited by this paper

• Mitochondria in T-cell tumor immunity and tumor therapies targeting mitochondria (Review)

  2026cites this paper
• Reactive oxygen species in cancer: Mechanistic insights and therapeutic innovations

  2025cites this paper
• Enhancement of Reactive Oxygen Species metabolism by antioxidant enzyme Cu/Zn-SOD can block betanodavirus-induced necroptosis and suppress viral replication in fish cells.

  2025cites this paper
• The heterogeneity of neutrophils in cancer and its implication for therapeutic targeting

  2025cites this paper
• A LRELHLNNN-Gal‑3 Modified Adipose Decellularized Scaffold To Construct Colorectal Cancer Model for Anticancer Drug Screening and Immunotherapy

  2025cites this paper
• Association of C-reactive protein-albumin-lymphocyte (CALLY) index with all-cause mortality in patients with type 2 diabetes: Results from the retrospective cohort study of NHANES 1999–2010

  2025cites this paper
• Redefining the synergistic toxicity of nano-plastics and cadmium in earthworm coelomocytes: the mechanism of α-amylase molecular docking orientation and energy crisis

  2025cites this paper
• Autocrine VEGF-B signaling maintains lipid synthesis and mitochondrial fitness to support T cell immune responses

  2024cites this paper
• Glucocorticoid-mediated Suppression of Effector Programming Assists the Memory Transition of Virus-specific CD8+ T Cells.

  2024cites this paper
• Mitochondrial chaperon TNF-receptor- associated protein 1 as a novel apoptotic regulator conferring susceptibility to Pneumocystis jirovecii pneumonia

  2024cites this paper
• Microplastics induced apoptosis in macrophages by promoting ROS generation and altering metabolic profiles.

  2024cites this paper
• The Multifaceted Roles of NRF2 in Cancer: Friend or Foe?

  2024cites this paper
• NiWo4- RGO composite exerts cytotoxic effects on pancreatic carcinoma cells via a cross-talk between reactive oxygen species-independent canonical autophagy of the mitochondria and epithelial-mesenchymal transition

  2024cites this paper
• 线粒体调控肿瘤免疫的研究进展

  2024cites this paper
• Reactive oxygen species: Janus-faced molecules in the era of modern cancer therapy

  2024cites this paper
• Unraveling the Role of Reactive Oxygen Species in T Lymphocyte Signaling

  2024cites this paper
• Nanocatalytic theranostics with intracellular mutual promotion for ferroptosis and chemo-photothermal therapy.

  2023cites this paper
• Dieckol, a natural polyphenolic drug, inhibits the proliferation and migration of colon cancer cells by inhibiting PI3K, AKT, and mTOR phosphorylation

  2023cites this paper
• Oxidative stress in pituitary neuroendocrine tumors: Affecting the tumor microenvironment and becoming a new target for pituitary neuroendocrine tumor therapy

  2023cites this paper
• Molecular mechanisms of ROS-modulated cancer chemoresistance and therapeutic strategies.

  2023cites this paper
• Effect of Diet and Oxidative Stress in the Pathogenesis of Lymphoproliferative Disorders

  2023cites this paper
• Influence of Cucurbiturils on the Production of Reactive Oxygen Species by T- and B-Lymphocytes, Platelets and Red Blood Cells

  2023cites this paper
• Immunoregulation: the interplay between metabolism and redox homeostasis

  2023cites this paper
• Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells

  2023cites this paper
• Site-selected in situ polymerization for living cell surface engineering

  2023cites this paper
• SOCS3 deletion in effector T cells confers an anti-tumorigenic role of IL-6 to the pro-tumorigenic cytokine.

  2023cites this paper
• Thioredoxin-interacting protein is essential for memory T cell formation via the regulation of the redox metabolism

  2023cites this paper
• Modulation of oxidative phosphorylation and mitochondrial biogenesis by cigarette smoke influence the response to immune therapy in NSCLC patients.

  2023cites this paper
• A bioinformatics analysis and an experimental validation of the hypoxia-related prognostic model

  2023cites this paper
• mTORC1 inhibition may improve T lymphocytes affected by aging

  2023cites this paper
• Muscle fiber necroptosis in pathophysiology of idiopathic inflammatory myopathies and its potential as target of novel treatment strategy

  2023cites this paper
• Dieckol prevents prostate cancer cell proliferation by transcriptionally attenuating JAK/STAT3 signaling pathway

  2023cites this paper
• DDB1 regulates the activation-induced apoptosis of T cells via downregulating the expression of histone methyltransferase SETD7

  2023cites this paper
• A PDA‐Functionalized 3D Lung Scaffold Bioplatform to Construct Complicated Breast Tumor Microenvironment for Anticancer Drug Screening and Immunotherapy

  2023cites this paper
• Targeting the Interplay of Independent Cellular Pathways and Immunity: A Challenge in Cancer Immunotherapy

  2023cites this paper
• Genetic alterations and oxidative stress in T cell lymphomas.

  2022cites this paper
• Context-dependent regulation of follicular helper T cell survival.

  2022cites this paper
• Cu2+ Embedded Three-Dimensional Covalent Organic Framework for Multiple ROS-Based Cancer Immunotherapy.

  2022cites this paper
• The Expression Pattern of Hypoxia-Related Genes Predicts the Prognosis and Mediates Drug Resistance in Colorectal Cancer

  2022cites this paper
• Use of Cannabis sativa derivatives for the treatment of lymphomas: what is known so far?

  2022cites this paper
• Mitochondrial oxidative stress in the tumor microenvironment and cancer immunoescape: foe or friend?

  2022cites this paper
• The microbiota and aging microenvironment in pancreatic cancer: Cell origin and fate.

  2022cites this paper
• Arginine-dependent immune responses

  2021cites this paper
• Selenium–GPX4 axis protects follicular helper T cells from ferroptosis

  2021cites this paper
• Training associated alterations in equine respiratory immunity using a multiomics comparative approach

  2021cites this paper
• Immune cell - produced ROS and their impact on tumor growth and metastasis

  2021cites this paper
• Oxidative Stress in the Tumor Microenvironment and Its Relevance to Cancer Immunotherapy

  2021cites this paper
• Cutting edge: Metabolic immune reprogramming, reactive oxygen species, and cancer

  2021cites this paper
• Interplay Between Reactive Oxygen/Reactive Nitrogen Species and Metabolism in Vascular Biology and Disease

  2021cites this paper
• Prognostic Stratification Based on HIF-1 Signaling for Evaluating Hypoxic Status and Immune Infiltration in Pancreatic Ductal Adenocarcinomas

  2021cites this paper
• Oxidative Stress Induces Mitochondrial Compromise in CD4 T Cells From Chronically HCV-Infected Individuals

  2021cites this paper
• Baseline Characteristics of Mitochondrial DNA and Mutations Associated With Short-Term Posttreatment CD4+T-Cell Recovery in Chinese People With HIV

  2021cites this paper
• Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity

  2021cites this paper
• Regulation of T Cells in Cancer by Nitric Oxide

  2021cites this paper
• Training-Associated Alterations In Equine Respiratory Immunity – A Multi-Omics Comparative Approach.

  2021cites this paper
• CD4+ Memory T-Cell Formation during Type 1 Immune Responses.

  2021cites this paper
• Hypoxia: Friend or Foe for drug delivery in Pancreatic Cancer.

  2020cites this paper
• Effect of Beta-Carotene Supplementation on the Peripheral Blood Leukocyte Population in Japanese Black Calves.

  2020cites this paper
• Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

  2020cites this paper
• Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation

  2020cites this paper
• An exacerbated metabolism and mitochondrial reactive oxygen species contribute to mitochondrial alterations and apoptosis in CD4 T cells during the acute phase of Trypanosoma cruzi infection.

  2020cites this paper
• Arginase 2 as a metabolic immune checkpoint in anti-tumor immunity

  2019cites this paper
• Biodegradable Nanoprodrugs: “Delivering” ROS to Cancer Cells for Molecular Dynamic Therapy

  2019cites this paper
• Advanced Glycation End-Products Suppress Mitochondrial Function and Proliferative Capacity of Achilles Tendon-Derived Fibroblasts

  2019cites this paper
• CD146 T cells in lung cancer: its function, detection, and clinical implications as a biomarker and therapeutic target

  2019cites this paper
• Hypoxia as a barrier to immunotherapy in pancreatic adenocarcinoma

  2019cites this paper
• In vitro peripheral blood mononuclear cell proliferation, cytokine secretion and oxidative stress modulation by pyrido[2,3-d] pyrimidines

  2019cites this paper
• Synthesis and characterization of Ursolic acid loaded poly (lactic-co-glycolic acid) nanoparticles and Caffiene loaded poly (lactic-co-glycolic acid) nanoparticles in colorectal cancer cell line

  2018cites this paper
• Possible Critical Role of Latent Chronic Toxoplasma Gondii Infection in Triggering, Development and Persistence of Autoimmune Diseases

  2018cites this paper
• Roles of TGF β and FGF Signals in the Lens: Tropomyosin Regulation for Posterior Capsule Opacity

  2018cites this paper
• Metabolic Reprogramming in Modulating T Cell Reactive Oxygen Species Generation and Antioxidant Capacity

  2018cites this paper
• Mitochondrial ROS and T Cell Activation

  2018cites this paper
• Multidrug Resistance for Cancer Treatment: Delivery of Ursolic Acid and Caffeine by Poly (Lactic-Co-Glycolic Acid) Nanoparticles

  2017cites this paper
• Dying to protect: cell death and the control of T‐cell homeostasis

  2017cites this paper
• for T Cell Proliferation Ataxia-Telangiectasia Mutated Is Required Regulation of Oxidative Stress Responses by

  2017cites this paper
• Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells.

  2017cites this paper
• Azacytidine Treatment Inhibits the Progression of Herpes Stromal Keratitis by Enhancing Regulatory T Cell Function

  2017cites this paper
• Aging of Antiviral CD8+ Memory T Cells Fosters Increased Survival, Metabolic Adaptations, and Lymphoid Tissue Homing

  2017cites this paper
• Biphasic response as a mechanism against mutant takeover in tissue homeostasis circuits

  2017cites this paper
• CC-223 blocks mTORC1/C2 activation and inhibits human hepatocellular carcinoma cells in vitro and in vivo

  2017cites this paper
• Smyd1C Mediates CD8 T Cell Death via Regulation of Bcl2-Mediated Restriction of outer Mitochondrial Membrane Integrity

  2017cites this paper
• Neferine Enhances the Antitumor Effect of Mitomycin‐C in Hela Cells Through the Activation of p38‐MAPK Pathway

  2017cites this paper
• Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress

  2017cites this paper
• Induction of arginase-1 in MDSC requires exposure to CD3/CD28 activated T cells

  2017cites this paper
• An Antifungal Mechanism of Protolichesterinic Acid from the Lichen Usnea albopunctata Lies in the Accumulation of Intracellular ROS and Mitochondria-Mediated Cell Death Due to Apoptosis in Candida tropicalis

  2017cites this paper
• NPC-26 kills human colorectal cancer cells via activating AMPK signaling

  2017influential citation
• Hepatitis C Virus–Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-γ Production by Altering Cellular Metabolism via Arginase-1

  2016cites this paper
• This information is current as via Arginase-1 Production by Altering Cellular Metabolism γ Suppressor Cells Suppress NK Cell IFN-Induced Myeloid-Derived − Hepatitis C Virus

  2016cites this paper
• MicroRNA-23a Curbs Necrosis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium.

  2016cites this paper
• Characterization and Use of Folate Receptor Isoforms for Targeting of Epithelial and Myeloid Cells

  2016cites this paper
• The Mucosal Immune System and Its Regulation by Autophagy

  2016cites this paper
• Contraction of intestinal effector T cells by retinoic acid-induced purinergic receptor P2X7

  2016cites this paper
• Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as p53-dependent and -independent apoptogenic signaling in melanoma cells.

  2016cites this paper
• MicroRNA-23 a Curbs Necr osis during Early T Cell Activation by Enforcing Intracellular Reactive Oxygen Species Equilibrium Graphical

  2016cites this paper
• cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response

  2016cites this paper
• Using Metalloporphyrins to Preserve β Cell Mass and Inhibit Immune Responses in Diabetes

  2016cites this paper
• Applied Nanotechnology and Nanoscience in Orthopedic Oncology.

  2016cites this paper
• Protective Effects of Hydrogen-Rich Saline on Rats with Smoke Inhalation Injury

  2015cites this paper
• Estrogen Deficiency and Osteoporosis

  2015cites this paper
• Tumour, Oxidative Stress and Host T Cell Response: Cementing the Dominance

  2015cites this paper