The kinase MK5 phosphorylates and activates Foxo1 at serine 215, and this modification is required for Foxo1 to induce Rag transcription.
MK5 activates Rag transcription via Foxo1 in developing B cells
Kwan T. Chow,G. Timblin,S. McWhirter,Mark Schlissel
Published 2013 in Journal of Experimental Medicine
ABSTRACT
PUBLICATION RECORD
- Publication year
2013
- Venue
Journal of Experimental Medicine
- Publication date
2013-07-29
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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