Standardizing double-blind, placebo-controlled oral food challenges: American Academy of Allergy, Asthma & Immunology-European Academy of Allergy and Clinical Immunology PRACTALL consensus report.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Allergy and Clinical Immunology

• Publication date

  2012-12-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.jaci.2012.10.017PMID 23195525
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Thermographic imaging during nasal peanut challenge may be useful in the diagnosis of peanut allergy

  2012cited by this paper
• Accurate oral food challenge requires a cumulative dose on a subsequent day.

  2012cited by this paper
• Development of a standardized low‐dose double‐blind placebo‐controlled challenge vehicle for the EuroPrevall project

  2012cited by this paper
• Exhaled nitric oxide decreases after positive food-allergen challenge

  2011cited by this paper
• NIAID-Sponsored 2010 Guidelines for Managing Food Allergy: Applications in the Pediatric Population

  2011cited by this paper
• Performance of a Component-Based Allergen-Microarray in the Diagnosis of Cow's Milk and Hen's Egg Allergy

  2011cited by this paper
• Performance of a component‐based allergen‐microarray in the diagnosis of cow's milk and hen's egg allergy

  2010cited by this paper
• Molecular diagnosis in allergy

  2010cited by this paper
• Allergy or tolerance in children sensitized to peanut: prevalence and differentiation using component-resolved diagnostics.

  2010cited by this paper
• Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel.

  2010cited by this paper
• A Novel Immunoassay Using Recombinant Allergens Simplifies Peanut Allergy Diagnosis

  2010cited by this paper
• Food allergy.

  2010cited by this paper
• Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report.

  2010cited by this paper
• The Prevalence of food hypersensitivity in young adults

  2009cited by this paper
• Wheat allergy

  2009cited by this paper
• Oral food challenge in children: an expert review.

  2009cited by this paper
• Soybean (Glycine max) allergy in Europe: Gly m 5 (beta-conglycinin) and Gly m 6 (glycinin) are potential diagnostic markers for severe allergic reactions to soy.

  2009cited by this paper
• Food allergy and food sensitization in early childhood: results from the DARC cohort

  2009cited by this paper
• Work Group report: oral food challenge testing.

  2009influential reference
• Predicting the outcome of oral food challenges with hen's egg through skin test end‐point titration

  2009cited by this paper
• Development of a novel peptide microarray for large-scale epitope mapping of food allergens.

  2009cited by this paper
• Fractional exhaled nitric oxide in infants during cow’s milk food challenge

  2008cited by this paper
• Profilin sensitization detected in the office by skin prick test: a study of prevalence and clinical relevance of profilin as a plant food allergen

  2008cited by this paper
• Utility of ovomucoid-specific IgE concentrations in predicting symptomatic egg allergy.

  2008cited by this paper
• Clinical usefulness of microarray‐based IgE detection in children with suspected food allergy

  2008cited by this paper
• Correlation between specific immunoglobulin E levels and the severity of reactions in egg allergic patients

  2008cited by this paper
• Hazelnut allergy: from pollen-associated mild allergy to severe anaphylactic reactions

  2008cited by this paper
• The use of serum-specific IgE measurements for the diagnosis of peanut, tree nut, and seed allergy.

  2008cited by this paper
• The role of wheat omega-5 gliadin IgE antibodies as a diagnostic tool for wheat allergy in childhood.

  2008cited by this paper
• Thresholds for food allergens and their value to different stakeholders

  2008influential reference
• Safety of open food challenges in the office setting.

  2008cited by this paper
• Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force Report *

  2008cited by this paper
• The role of protein digestibility and antacids on food allergy outcomes.

  2008cited by this paper
• Correlation of serum allergy (IgE) tests performed by different assay systems.

  2008cited by this paper
• Should children with a history of anaphylaxis to foods undergo challenge testing?

  2008cited by this paper
• Pitfalls in double‐blind, placebo‐controlled oral food challenges

  2007cited by this paper
• Methodological issues in the diagnostic work-up of food allergy: a real challenge.

  2007cited by this paper
• Eczematous reactions to food in atopic eczema: position paper of the EAACI and GA2LEN

  2007cited by this paper
• Lupine allergy: not simply cross-reactivity with peanut or soy.

  2007cited by this paper
• Placebo reactions in double‐blind, placebo‐controlled food challenges in children

  2007cited by this paper
• Allergen immunotherapy: a practice parameter third update.

  2007cited by this paper
• Diagnosis of Food Allergy in Children: Toward a Standardization of Food Challenge

  2007cited by this paper
• Correlation between skin prick test using commercial extract of cow's milk protein and fresh milk and food challenges.

  2007cited by this paper
• Facial thermography is a sensitive and specific method for assessing food challenge outcome

  2007cited by this paper
• Correlation between skin prick test using commercial extract of cow's milk protein and fresh milk and food challenges

  2007cited by this paper
• EAACI/GA2LEN Position paper: Present status of the atopy patch test *

  2006cited by this paper
• Acute allergic reactions in children with AEDS after prolonged cow's milk elimination diets

  2006cited by this paper
• Risk-taking and Coping Strategies of Food Allergic Adolescents and Young Adults

  2006cited by this paper
• Determination of no-observed-adverse-effect levels and eliciting doses in a representative group of peanut-sensitized children.

  2006cited by this paper
• The diagnosis of Brazil nut allergy using history, skin prick tests, serum‐specific immunoglobulin E and food challenges

  2006cited by this paper
• Continuing food‐avoidance diets after negative food challenges

  2006cited by this paper
• Second symposium on the definition and management of anaphylaxis: summary report--Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium.

  2006cited by this paper
• 9. Food allergy.

  2006cited by this paper
• The atopy patch test in the diagnostic workup of suspected food-related symptoms in children.

  2006cited by this paper
• Diagnostic Tests Based on Human Basophils: Potentials, Pitfalls and Perspectives

  2006cited by this paper
• The predictive value of the skin prick test weal size for the outcome of oral food challenges

  2005cited by this paper
• The prevalence of peanut sensitization and the association to pollen sensitization in a cohort of unselected adolescents – The Odense Adolescence Cohort Study on Atopic Diseases and Dermatitis (TOACS)

  2005cited by this paper
• Utility of the ratio of food‐specific IgE/total IgE in predicting symptomatic food allergy in children

  2005cited by this paper
• Symposium on the definition and management of anaphylaxis: summary report.

  2005cited by this paper
• Food allergy – accurately identifying clinical reactivity

  2005cited by this paper
• The predictive value of specific immunoglobulin E levels in serum for the outcome of oral food challenges

  2005cited by this paper
• Does severity of low‐dose, double‐blind, placebo‐controlled food challenges reflect severity of allergic reactions to peanut in the community?

  2005cited by this paper
• The use of patch testing in the diagnosis of food allergy

  2005cited by this paper
• The clinical relevance of sensitization to pollen‐related fruits and vegetables in unselected pollen‐sensitized adults

  2005cited by this paper
• Statistical issues in clinical trials that involve the double-blind, placebo-controlled food challenge.

  2005cited by this paper
• The diagnosis and management of anaphylaxis: an updated practice parameter.

  2005cited by this paper
• Development and validation of challenge materials for double-blind, placebo-controlled food challenges in children.

  2004cited by this paper
• Role of food allergy in atopic dermatitis

  2004cited by this paper
• The relationship of allergen-specific IgE levels and oral food challenge outcome.

  2004cited by this paper
• Standardization of food challenges in patients with immediate reactions to foods – position paper from the European Academy of Allergology and Clinical Immunology

  2004influential reference
• A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?

  2004cited by this paper
• Risk of oral food challenges.

  2004cited by this paper
• Birch pollen‐related food as a provocation factor of allergic symptoms in children with atopic eczema/dermatitis syndrome

  2004cited by this paper
• Late eczematous reactions to food in children with atopic dermatitis

  2004cited by this paper
• Threshold levels in food challenge and specific IgE in patients with egg allergy: is there a relationship?

  2003cited by this paper
• Presentation of allergen in different food preparations affects the nature of the allergic reaction – a case series

  2003cited by this paper
• 9. Food allergy.

  2003cited by this paper
• Food allergy

  2002influential reference
• The distribution of individual threshold doses eliciting allergic reactions in a population with peanut allergy.

  2002cited by this paper
• Statistical model for assessing the proportion of subjects with subjective sensitisations in adverse reactions to foods

  2001cited by this paper
• The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials.

  2001cited by this paper
• Variations of serum eosinophil cationic protein and tryptase, measured in serum and saliva, during the course of immediate allergic reactions to foods

  2001cited by this paper
• Utility of food-specific IgE concentrations in predicting symptomatic food allergy.

  2001cited by this paper
• The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials

  2001cited by this paper
• Clinical implications of cross-reactive food allergens.

  2001cited by this paper
• The Revised CONSORT Statement for Reporting Randomized Trials: Explanation and Elaboration

  2001cited by this paper
• The CONSORT statement: revised recommendations for improving the quality of reports of parallel group randomized trials

  2001cited by this paper
• Dose-response in double-blind, placebo-controlled oral food challenges in children with atopic dermatitis.

  2000cited by this paper
• Specificity of allergen skin testing in predicting positive open food challenges to milk, egg and peanut in children

  2000cited by this paper
• Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens.

  1999cited by this paper
• Food allergy. Part 2: diagnosis and management.

  1999cited by this paper
• Outcome of double‐blind, placebo‐controlled food challenge tests in 107 children with atopic dermatitis

  1999cited by this paper
• An evaluation of the sensitivity of subjects with peanut allergy to very low doses of peanut protein: a randomized, double-blind, placebo-controlled food challenge study.

  1997cited by this paper
• Relationship between food-specific IgE concentrations and the risk of positive food challenges in children and adolescents.

  1997cited by this paper
• Airway reactivity changes in asthmatic patients undergoing blinded food challenges.

  1996cited by this paper
• The role of eosinophils and eosinophil cationic protein in monitoring oral challenge tests in children with food-sensitive atopic dermatitis.

  1994cited by this paper
• Skin testing with natural foods in patients suspected of having food allergies: is it a necessity?

  1994cited by this paper
• Serum tryptase and urinary 1-methylhistamine as parameters for monitoring oral food challenges in children.

  1994cited by this paper
• Proposals for standardization of oral food challenge tests in infants and children

  1994cited by this paper
• Respiratory reactions provoked by double-blind food challenges in children.

  1994cited by this paper

• Clinical and demographic features of children with legume allergy in a tertiary allergy clinic

  2026cites this paper
• Precision Medicine in Plant Food Allergy: a Systematic Review of Biomarkers Under a Clinical Approach

  2026cites this paper
• High- and Low-Dose Oral Sesame Immunotherapy: Interim Analysis of a Randomized Single-Center Open-Label Trial

  2026influential citation
• Efficacy and Safety of Ligelizumab in Individuals With Confirmed Peanut Allergy.

  2026cites this paper
• Safety of a novel oral immunotherapy approach in preschool children with single and multiple food allergies

  2026cites this paper
• Effect of cow's milk protein allergy during infancy on eating behavior at 4 years of age: A cohort study.

  2026cites this paper
• House dust allergens of children with newly diagnosed hazelnut or sesame allergy.

  2026cites this paper
• Confronting fear and uncertainty: adults’ experiences of undergoing a food challenge test for food allergy

  2026influential citation
• A retrospective cohort study of supervised and home baked and/or neat hen's egg challenge for pediatric IgE hen's egg allergy

  2026cites this paper
• Does Previous Anaphylaxis Determine Differences Between Patients Undergoing Oral Food Challenges to Cow’s Milk and Hen’s Egg?

  2026cites this paper
• Food Allergy Prevalence in Two Population‐Based UK Cohorts Born 12 Years Apart

  2025cites this paper
• Can Faecal Eosinophil Cationic Protein and β-Defensin-2 Levels Be Useful in the Diagnosis and Follow-Up of Infants with Milk-Protein-Induced Allergic Proctocolitis?

  2025cites this paper
• [Position paper on procedures in allergology. Asociación Colombiana de Alergia Asma e Inmunología (ACAAI)].

  2025cites this paper
• Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges.

  2025cites this paper
• Re-evaluating treatment success in trials of peanut oral-immunotherapy: impact of different definitions on efficacy outcomes

  2025cites this paper
• Safer oral immunotherapy with very low-dose introduction for pediatric hen’s egg allergy

  2025cites this paper
• Peanut Oral Immunotherapy in Children with High-Threshold Peanut Allergy.

  2025cites this paper
• Walnut Allergy in Children: A Diagnostic Test Accuracy Study

  2025cites this paper
• Oral Food Challenges: The Standard of Diagnosis.

  2025cites this paper
• Diagnosing IgE-mediated food allergy: How to apply the latest guidelines in clinical practice

  2025cites this paper
• Prevalence and risk factors of de novo atopic diseases in pediatric liver transplant recipients: A retrospective cohort study

  2025cites this paper
• Predicting Severe and Early-Onset Reactions with the Tahini-Lip Dose Challenge.

  2025cites this paper
• Trends over a decade in the prevalence and eliciting dose of peanut and tree nut allergies in Japan

  2025cites this paper
• Shrimp oral immunotherapy outcomes in the phase 2 clinical trial: MOTIF

  2025cites this paper
• Beyond anaphylaxis: a multidimensional exploration of sesame allergy in a globalized world.

  2025cites this paper
• Compositional Knowledge Graph for Clinical Decision Support in Pediatric Allergy Diagnostics

  2025cites this paper
• Probiotic oral immunotherapy for egg and milk allergy induces sustained unresponsiveness

  2025cites this paper
• Natural history of sesame allergy in pediatric patients: Insight from a retrospective analysis

  2025cites this paper
• Real‐World Impact on Dietary Intake and Quality of Life Post‐Successful Oral Food Challenge to Peanut and Tree Nuts

  2025cites this paper
• Cow’s Milk Protein Allergy: ETAPA Survey on Pediatric Management and Tolerance Acquisition

  2025cites this paper
• Development of a clinical predictive score for allergic reactions during oral food challenges in pediatric patients

  2025cites this paper
• Serum albumin sensitization in children with cow's milk allergy: Clinical relevance to red meat reactions

  2025cites this paper
• Traduction et republication de « Recommandations de l’EAACI sur le diagnostic de l’allergie alimentaire médiée par les IgE »

  2025cites this paper
• A Growing Cause of Food Allergies in Children: Sesame

  2025cites this paper
• Food allergy concurrent with atopic dermatitis: Correlation with age of onset and severity.

  2025cites this paper
• Efficacy of cashew nut protein immunotherapy: protocol for a single-centre randomised controlled trial in a Polish paediatric population

  2025cites this paper
• Pragmatic Low‐Dose Oral Immunotherapy for Preschool Children With Peanut Allergy: A Randomised Controlled Trial

  2025cites this paper
• Natural Course and Predictors of Clinical Resolution in Pediatric Cashew Nut Allergy

  2025cites this paper
• Real‐World Evaluation of Associations Between Regular Intake and Food Challenge Outcome in Children

  2025cites this paper
• Oral Immunotherapy in Peanut‐Allergic Adults Using Real‐World Materials

  2025cites this paper
• Prevalence of Intolerance to Amines and Salicylates in Individuals with Atopic Dermatitis: A Systematic Review and Meta-Analysis

  2025influential citation
• Integrated Diagnostic Approach Using Basophil Activation Test and IgE Assays for Shrimp and Prawn Allergy

  2025cites this paper
• Understanding the Variability of Peanut‐Oral Immunotherapy Responses by Multi‐Omics Profiling of Immune Cells

  2025cites this paper
• Casein sIgE as the most accurate predictor for heated milk tolerance in Finnish children

  2025cites this paper
• Oral Peanut Immunotherapy With Butyrate Adjuvant (OPIA) in Children: A Randomised, Controlled Trial

  2025cites this paper
• The Basophil Activation Test Is the Most Accurate Test in Predicting Allergic Reactions to Baked and Fresh Cow's Milk During Oral Food Challenges

  2025cites this paper
• IgE-mediated coconut allergy in tropical Singapore

  2025cites this paper
• Integrating Ara h 2 sIgE with SPT reduces oral food challenges and costs in peanut allergy diagnosis: A cost comparison analysis

  2025cites this paper
• Fish Allergenicity Ladder and Parvalbumin Epitopes for Predicting Clinical Cross‐Reactivity and Reintroduction in Chinese Population

  2025cites this paper
• Long term impact of formula choice in children with cow milk protein allergy: 6-year follow-up of the Atopic March Cohort Study.

  2025cites this paper
• Hazelnut oral immunotherapy desensitizes hazelnut but not other tree nut allergies (Nut CRACKER Study).

  2025cites this paper
• Detection of Anaphylaxis Through the Cutaneous Barrier

  2025cites this paper
• Anaphylaxis severity grade, during oral food challenges, assessed by five different classifications

  2025cites this paper
• Peanut Allergy Diagnosis: Current Practices, Emerging Technologies, and Future Directions

  2025cites this paper
• Insights into self-reported food allergies in Romanian schoolchildren

  2025cites this paper
• Developing a Standardised National Model of Care for Treatment of Peanut Allergy in Infants: The ADAPT Peanut Oral Immunotherapy Program.

  2025cites this paper
• Peanut oral immunotherapy using 30 mg and 300 mg maintenance doses.

  2025cites this paper
• Assessment of food allergies in patients under two years of age with skin manifestations referred to pediatric immunology and allergy outpatient clinic

  2025cites this paper
• Asthma and Multi-Food Allergy Are Risk Factors for Oral Food Challenge Failure—A Single-Center Experience

  2025cites this paper
• Baked-Milk Modulates Cow's Milk Allergy in Children: Impact of Phenotype, Age, Intake.

  2025cites this paper
• Eating away at food allergy

  2025cites this paper
• Randomised, Double-Blinded, Placebo-Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions.

  2025cites this paper
• Immune therapies in coeliac disease and food allergies: Advances, challenges, and opportunities.

  2025cites this paper
• Relationship Between Air Pollution and the Incidence of Selected Disease Among Children and Adolescents in the Years 2017-2023 in Selected Cities in Poland

  2024cites this paper
• AAAAI–EAACI PRACTALL: Standardizing oral food challenges—2024 Update

  2024cites this paper
• Safety of oral immunotherapy for cashew nut and peanut allergy in children - a retrospective single-centre study.

  2024cites this paper
• Omalizumab reduces anaphylactic reactions and allows food introduction in food‐allergic in children with severe asthma: An observational study

  2024cites this paper
• Diagnostic Accuracy of Skin Prick Test, Food‐Specific IgE and Component Testing for IgE‐Mediated Peanut, Egg, Milk and Wheat Allergy

  2024cites this paper
• Management and disease burden of children and adults with severe IgE-mediated food allergy: Are adults the lost population?

  2024cites this paper
• Diagnosis and management of shrimp allergy

  2024cites this paper
• Pediatric idiopathic anaphylaxis: practical management from infants to adolescents

  2024cites this paper
• Efficacy and safety of low-dose sesame oral immunotherapy in paediatric patients: a protocol for a single-centre, randomised controlled trial

  2024cites this paper
• Can Faecal Zonulin and Calprotectin Levels Be Used in the Diagnosis and Follow-Up in Infants with Milk Protein-Induced Allergic Proctocolitis?

  2024cites this paper
• Allergenic Biomarkers in the Molecular Diagnosis of IgE-Mediated Wheat Allergy

  2024cites this paper
• Comparison of skin prick test and prick‐to‐prick test with fruits and vegetables in the diagnosis of food allergy

  2024cites this paper
• Outcomes of Oral Food Challenges Conducted in a Paediatric Tertiary Centre in Singapore

  2024cites this paper
• Is Component-Specific Antibody Testing Sufficient to Replace the Oral Food Challenge in the Diagnostics of Peanut-Sensitized Children? A Proof-of-Concept Study

  2024cites this paper
• History of food allergy and where we are today

  2024cites this paper
• Omalizumab for the reduction of allergic reactions to foods: a narrative review

  2024cites this paper
• Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT.

  2024cites this paper
• Profiles of apple allergen components and its diagnostic value in Northern China

  2024cites this paper
• A Streamlined Strategy for Basophil Activation Testing in a Multicenter Phase III Clinical Trial.

  2024cites this paper
• Bruton’s tyrosine kinase inhibition for the treatment of allergic disorders

  2024cites this paper
• Management of food allergy based on oral food challenge

  2024cites this paper
• A Practical Guide for Implementing Omalizumab Therapy for Food Allergy.

  2024cites this paper
• Varying Doses of Epicutaneous Immunotherapy With Viaskin Milk vs Placebo in Children With Cow’s Milk Allergy

  2024cites this paper
• Anaphylactic reaction requiring epinephrine in a 10‐year‐old patient undergoing peanut challenge while on dupilumab therapy

  2024cites this paper
• Current and future perspectives on the consensus guideline for food protein-induced enterocolitis syndrome (FPIES).

  2024cites this paper
• Management of Food Allergies and Food-Related Anaphylaxis.

  2024cites this paper
• Evaluation of clinical outcomes of efficacy in food allergen immunotherapy trials, COFAITH EAACI task force

  2024influential citation
• Safety and efficacy of epicutaneous immunotherapy with DBV712 (peanut patch) in peanut allergy

  2024cites this paper
• Growth pattern of paediatric patients affected by cow milk protein allergy fed with rice hydrolyzed formula.

  2024cites this paper
• Exploratory immunogenicity outcomes of peanut oral immunotherapy: Findings from the PALISADE trial

  2024cites this paper
• Clinical outcome and component-specific antibody levels in egg allergic children after lightened oral immunotherapy.

  2024cites this paper
• Safe selection of children with a suspected food allergy to introduce peanut or tree nuts at home

  2024cites this paper
• Omalizumab for the Treatment of Multiple Food Allergies.

  2024cites this paper
• Eliciting and stop dose during oral food challenges for peanut and common tree nuts in different age groups

  2024influential citation
• Novel Diagnostics in Food Allergy.

  2024cites this paper
• Efficacy of very-low-dose oral food challenge in children with severe hen egg allergy: A retrospective, single-center case series.

  2024cites this paper
• The efficacy and safety of stepwise oral food challenge in children with hen’s egg allergy

  2024cites this paper