Podocyte alpha-actinin induction precedes foot process effacement in experimental nephrotic syndrome.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  American Journal of Physiology

• Publication date

  1997-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPRENAL.1997.273.1.F150PMID 9249603
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Ultrastructural changes in glomerular epithelial cells in acute puromycin aminonucleoside nephrosis: A study by high-resolution scanning electron microscopy

  2005cited by this paper
• Cytoskeletal changes in podocytes associated with foot process effacement in Masugi nephritis.

  1996cited by this paper
• Distribution of extracellular matrix receptors in various forms of glomerulonephritis.

  1995cited by this paper
• Integrins and signal transduction pathways: the road taken.

  1995cited by this paper
• Beta-1 integrins in the normal human glomerular capillary wall: an immunoelectron microscopy study.

  1994cited by this paper
• Podocytic cytoskeletal disaggregation and basement-membrane detachment in puromycin aminonucleoside nephrosis.

  1993cited by this paper
• Mechanisms of proteinuria in noninflammatory glomerular diseases.

  1993cited by this paper
• Mapping of the alpha-actinin binding site within the beta 1 integrin cytoplasmic domain.

  1993cited by this paper
• Characterization of glomerular epithelial cell matrix receptors.

  1992cited by this paper
• Very late activation-3 integrin is the dominant beta 1-integrin on the glomerular capillary wall: an immunofluorescence study in nephrotic syndrome.

  1992cited by this paper
• Cell-matrix adhesion receptors: relevance to glomerular pathology.

  1992cited by this paper
• Adhesion of rat glomerular epithelial cells to extracellular matrices: role of beta 1 integrins.

  1992cited by this paper
• Integrin receptors in the glomerulus: potential role in glomerular injury.

  1992cited by this paper
• Mesangial cell activation by bacterial endotoxin. Induction of rapid cytoskeletal reorganization and gene expression.

  1991cited by this paper
• Podocytes in glomerulus of rat kidney express a characteristic 44 KD protein.

  1991cited by this paper
• Contractile proteins in podocytes: immunocytochemical localization of actin and alpha-actinin in normal and nephrotic rat kidneys

  1991cited by this paper
• Cellular receptors for matrix proteins in normal human kidney and human mesangial cells.

  1990cited by this paper
• Ultrastructural organization of contractile proteins in rat glomerular mesangial cells.

  1990cited by this paper
• A beta 1-integrin receptor for fibronectin in human kidney glomeruli.

  1989cited by this paper
• Glomerular epithelial detachment, not reduced charge density, correlates with proteinuria in adriamycin and puromycin nephrosis.

  1989cited by this paper
• Ultrastructural organization of contractile and cytoskeletal proteins in glomerular podocytes of chicken, rat, and man.

  1988cited by this paper
• Hydrogen peroxide (H2O2) induces actin and some heat-shock proteins in Drosophila cells.

  1988cited by this paper
• ACTIN FILAMENT ALTERATIONS IN GLOMERULAR EPITHELIAL CELLS OF ADRIAMYCIN‐INDUCED NEPHROTIC RATS

  1986cited by this paper
• Glomerular cell culture.

  1985cited by this paper
• Quantitative indexes of aminonucleoside-induced nephrotic syndrome.

  1984cited by this paper
• Cytoskeleton ultrastructure of podocytes and glomerular endothelial cells in man and in the rat

  1984cited by this paper
• Filamentous actin bundles in the kidney

  1984cited by this paper
• Improved methods for culturing rat glomerular cells.

  1984cited by this paper
• The detection of effaced podocytes by high resolution light microscopy.

  1982cited by this paper
• Isolation and characterization of rat glomerular epithelial cells in vitro.

  1978cited by this paper
• Alterations of the glomerular epithelium in acute aminonucleoside nephrosis. Evidence for formation of occluding junctions and epithelial cell detachment.

  1976cited by this paper
• An ultrastructural study of the mechanisms of proteinuria in aminonucleoside nephrosis.

  1975cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• AN ELECTRON MICROSCOPE STUDY OF THE GLOMERULUS IN NEPHROSIS, GLOMERULONEPHRITIS, AND LUPUS ERYTHEMATOSUS

  1957cited by this paper

• MAGI-2 Regulates the Organization of Podocyte Actin Cytoskeleton Through its Interaction with α-Actinin-4 and Synaptopodin.

  2025cites this paper
• Early use of renin–angiotensin–aldosterone system inhibitors and stable renal function in familial focal segmental glomerulosclerosis with ACTN4 mutation: a case report and literature review

  2025cites this paper
• Hidden genetics behind glomerular scars: an opportunity to understand the heterogeneity of focal segmental glomerulosclerosis?

  2023cites this paper
• Integrated Analysis of Multiple Microarray Studies to Identify Core Gene-Expression Signatures Involved in Tubulointerstitial Injury in Diabetic Nephropathy

  2022cites this paper
• α-Parvin Defines a Specific Integrin Adhesome to Maintain the Glomerular Filtration Barrier

  2022cites this paper
• Monogenic focal segmental glomerulosclerosis: A conceptual framework for identification and management of a heterogeneous disease

  2022cites this paper
• Circulating Permeability Factors in Focal Segmental Glomerulosclerosis: In Vitro Detection

  2022cites this paper
• Role of cathepsin L in idiopathic nephrotic syndrome in children.

  2020cites this paper
• Childhood Idiopathic Nephrotic Syndrome as a Podocytopathy

  2019cites this paper
• Focal segmental glomerulosclerosis ACTN4 mutants binding to actin: regulation by phosphomimetic mutations

  2019cites this paper
• Reversible SAHH inhibitor protects against glomerulonephritis in lupus-prone mice by downregulating renal α-actinin-4 expression and stabilizing integrin-cytoskeleton linkage

  2019cites this paper
• The importance of genetic study in steroid-resistant nephrotic syndrome

  2019cites this paper
• Нарушения клубочкового фильтрационного барьера как причина протеинурии при нефротическом синдроме

  2019cites this paper
• Genetic and acquired abnormalities in C3 glomerulopathy and primary immune complex-mediated MPGN

  2018cites this paper
• Knockdown of NUP160 inhibits cell proliferation, induces apoptosis, autophagy and cell migration, and alters the expression and localization of podocyte associated molecules in mouse podocytes.

  2018cites this paper
• Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria

  2018cites this paper
• Mechanical challenges and cytoskeletal impairments in focal segmental glomerulosclerosis.

  2018cites this paper
• Anti-dsDNA antibodies and resident renal cells - Their putative roles in pathogenesis of renal lesions in lupus nephritis.

  2017cites this paper
• Visualisation studies and glomerular filtration in early diabetic rats.

  2017cites this paper
• Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy.

  2017cites this paper
• YAP-mediated mechanotransduction determines the podocyte’s response to damage

  2017cites this paper
• Podocyte–actin dynamics in health and disease

  2016cites this paper
• Immunohistochemical and electronmicroscopic features of mesenchymal-to-epithelial transition in human developing, postnatal and nephrotic podocytes

  2016cites this paper
• The role of podocyte genetics in childhood nephrotic syndrome

  2016cites this paper
• Pathogenesis of idiopathic nephrotic syndrome in children: molecular mechanisms and therapeutic implications

  2016cites this paper
• Podocyturia is significantly elevated in untreated vs treated Fabry adult patients

  2016cites this paper
• Upregulation of α3β1-Integrin in Podocytes in Early-Stage Diabetic Nephropathy

  2016cites this paper
• Regulation of Podocyte apoptosis in Diabetic Kidney Disease - Role of SHIP2, PDK1 and CDK2

  2016cites this paper
• Identification and characterization of LMX1B target genes

  2016influential citation
• Endothelin and the glomerulus in chronic kidney disease.

  2015cites this paper
• The Short‐Term Effects of C‐Peptide on the Early Diabetes‐Related Ultrastructural Changes to the Podocyte Slit Diaphragm of Glomeruli in Rats

  2015cites this paper
• Podocytes … What’s Under Yours? (Podocytes and Foot Processes and How They Change in Nephropathy)

  2015cites this paper
• The role of alpha-actinin-4 in human kidney disease

  2015cites this paper
• The Podocyte Cytoskeleton: Key to a Functioning Glomerulus in Health and Disease

  2014cites this paper
• TGF-β-induced pathogenic changes in mouse podocytes

  2014cites this paper
• Na þ / H þ exchanger-1 reduces podocyte injury caused by endoplasmic reticulum stress via autophagy activation

  2014cites this paper
• Molecular mechanisms regulating glucose uptake into podocytes: The roles of ezrin, septin 7 and nonmuscle myosin IIA

  2014cites this paper
• Podocytes as a therapeutic target

  2014cites this paper
• Na+/H+ exchanger-1 reduces podocyte injury caused by endoplasmic reticulum stress via autophagy activation

  2014cites this paper
• Glomerular Filtration Barrier Assembly: An insight.

  2013cites this paper
• Central Annals of Clinical and Experimental Hypertension

  2013cites this paper
• Genetic Abnormalities in Glomerular Function

  2013cites this paper
• The podocyte's response to stress: the enigma of foot process effacement.

  2013cites this paper
• Cell–matrix adhesion of podocytes in physiology and disease

  2013cites this paper
• An Overview of Molecular Mechanism of Nephrotic Syndrome

  2012cites this paper
• The spectrum of HIV related nephropathy in KwaZulu-Natal : a pathogenetic appraisal and impact of HAART.

  2012cites this paper
• Alpha-actinin: a multidisciplinary protein with important role in B-cell driven autoimmunity.

  2011cites this paper
• The effects of PTK787/ZK222584, an inhibitor of VEGFR and PDGFRβ pathways, on intussusceptive angiogenesis and glomerular recovery from Thy1.1 nephritis.

  2011cites this paper
• TM4SF10 and ADAP interaction in podocytes: role in Fyn activity and nephrin phosphorylation.

  2011cites this paper
• Cardiovascular , Pulmonary and Renal Pathology Alterations in Fatty Acid Utilization and an Impaired Antioxidant Defense Mechanism Are Early Events in Podocyte Injury A Proteomic Analysis

  2010cites this paper
• Therapeutic potential of endothelin receptor antagonists for chronic proteinuric renal disease in humans.

  2010cites this paper
• Transcriptome Analysis of the Response of Cultured Murine Podocytes to Puromycin Aminonucleoside

  2010cites this paper
• Permeability, Ultrastructural Changes, and Distribution of Novel Proteins in the Glomerular Barrier in Early Puromycin Aminonucleoside Nephrosis

  2010cites this paper
• Expression of Podocyte-Associated Molecules in Acquired Human Kidney Diseases 2

  2009cites this paper
• Alterations in fatty acid utilization and an impaired antioxidant defense mechanism are early events in podocyte injury: a proteomic analysis.

  2009cites this paper
• Inducible rodent models of acquired podocyte diseases.

  2009cites this paper
• Focal Segmental Glomerulosclerosis

  2009cites this paper
• Monogene Ursachen des nephrotischen Syndroms

  2009cites this paper
• Reversal of proteinuric renal disease and the emerging role of endothelin

  2008cites this paper
• Dissociation of NEPH1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis.

  2008cites this paper
• Curriculum Vitae Personal Data

  2008cites this paper
• Activation of adenosine 2A receptors preserves structure and function of podocytes.

  2008cites this paper
• Proteinuria in diabetic kidney disease: A mechanistic

  2008cites this paper
• alpha-Actinin-4 and the podocyte: Implications for focal segmental glomerulosclerosis

  2008cites this paper
• Dissociation of NEPH 1 from nephrin is involved in development of a rat model of focal segmental glomerulosclerosis

  2008cites this paper
• Novel treatment strategies for antibody-mediated diseases: targeting long-lived plasma cells

  2008cites this paper
• Expression of alpha-actinin-4 in human diabetic nephropathy.

  2008cites this paper
• Emerging Roles for Metabolic Engineering - Understanding Primitive and Complex Metabolic Models and Their Relevance to Healthy and Diseased Kidney Podocytes

  2008cites this paper
• CHAPTER 85 – Genetic Abnormalities in Glomerular Function

  2008cites this paper
• Proteinuria in diabetic kidney disease: a mechanistic viewpoint.

  2008cites this paper
• Nephrin : Intracellular trafficking and podocyte maturation

  2007cites this paper
• α-Actinin-4 Is Required for Normal Podocyte Adhesion*

  2007cites this paper
• Familial focal segmental glomerulosclerosis and retinitis pigmentosa: a new association.

  2007cites this paper
• Podocyte Injury and Glomerulosclerosis in Hyperhomocysteinemic Rats

  2007cites this paper
• FSGS-associated α-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes

  2006cites this paper
• FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes.

  2006cites this paper
• The podocyte's response to injury: role in proteinuria and glomerulosclerosis.

  2006cites this paper
• Reduced podocyte expression of alpha3beta1 integrins and podocyte depletion in patients with primary focal segmental glomerulosclerosis and chronic PAN-treated rats.

  2006cites this paper
• High glucose and advanced glycosylated end‐products affect the expression of α‐actinin‐4 in glomerular epithelial cells

  2006cites this paper
• New insights into the molecular biology of the glomerular filtration barrier and associated disease

  2005cites this paper
• NEPHRIN IN DIABETES AND IN DIABETES-RELATED CONDITIONS Emphasis on urinary proteins immunoreactive with nephrin antibodies

  2005cites this paper
• Differential proteomic analysis of proteins induced by glucocorticoids in cultured murine podocytes.

  2005cites this paper
• NEPHRIN IN DIABETES AND IN DIABETES-RELATED CONDITIONS Emphasis on urinary proteins immunoreactive with nephrin antibodies

  2005cites this paper
• Spectrin, alpha-actinin, and dystrophin.

  2005cites this paper
• Podocytes in childhood minimal change nephrotic syndrome

  2005cites this paper
• Analysis of NPHS1, NPHS2, ACTN4, and WT1 in Japanese patients with congenital nephrotic syndrome.

  2005cites this paper
• Genetics of idiopathic nephrotic syndrome

  2005cites this paper
• Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization.

  2005cites this paper
• 最近の腎臓病学の進歩とあゆみ―Slit diaphragmと糸球体腎炎を中心に―

  2005cites this paper
• Recent Advances in Nephrology:Slit Diaphragm and Glomerulonephritis

  2005cites this paper
• Extracellular matrix regulates glomerular epithelial cell survival and proliferation.

  2004cites this paper
• Expression of alpha-actinin-4 in acquired human nephrotic syndrome: a quantitative immunoelectron microscopy study.

  2004cites this paper
• Dynamic (re)organization of the podocyte actin cytoskeleton in the nephrotic syndrome

  2004cites this paper
• α-Actinin-4-Mediated FSGS: An Inherited Kidney Disease Caused by an Aggregated and Rapidly Degraded Cytoskeletal Protein

  2004cites this paper
• Podocyte proteomics.

  2004cites this paper
• Is alpha-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis?

  2004cites this paper
• Is α-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis?

  2004cites this paper
• Detection of Injury-induced Changes in Gene Expression of the Glomerular Epithelial Cell-specific Marker , Wilm ’ s Tumor-1 , by Laser Capture Microdissection

  2004cites this paper
• Nephrin expression, localization and role as an interacting molecule : Emphasis on kidney glomerular podocytes

  2003cites this paper
• Actin Filament Organization of Foot Processes in Rat Podocytes

  2003cites this paper