Spatio‐temporal analysis of gene expression during aging in Drosophila melanogaster

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Aging Cell

• Publication date

  2002-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1474-9728.2002.00007.xPMID 12882353
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Application of the gene search system to screen for longevity genes in Drosophila

  2004cited by this paper
• Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster.

  2002cited by this paper
• Differential Gene Expression and Aging

  2002cited by this paper
• Requirement for a Peptidoglycan Recognition Protein (PGRP) in Relish Activation and Antibacterial Immune Responses in Drosophila

  2002cited by this paper
• The Drosophila immune response against Gram-negative bacteria is mediated by a peptidoglycan recognition protein

  2002cited by this paper
• Interaction between nitric oxide and subsets of human T lymphocytes with differences in glutathione metabolism

  2002cited by this paper
• Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli

  2002cited by this paper
• Mechanisms of aging: public or private?

  2002cited by this paper
• Drosophila stathmin: a microtubule-destabilizing factor involved in nervous system formation.

  2002cited by this paper
• Influences of aging and caloric restriction on the transcriptional profile of skeletal muscle from rhesus monkeys

  2001cited by this paper
• [The microtubule-associated protein tau in neurodegenerative diseases. Tauopathies].

  2001cited by this paper
• Peptidoglycan Recognition Proteins A NOVEL FAMILY OF FOUR HUMAN INNATE IMMUNITY PATTERN RECOGNITION MOLECULES*

  2001cited by this paper
• Peptidoglycan Recognition Proteins

  2001cited by this paper
• In vivo analysis of Drosophila bicoid mRNA localization reveals a novel microtubule-dependent axis specification pathway.

  2001cited by this paper
• Genome-wide analysis of the Drosophila immune response by using oligonucleotide microarrays

  2001cited by this paper
• The effects of aging on gene expression in the hypothalamus and cortex of mice.

  2001cited by this paper
• J-Express: exploring gene expression data using Java

  2001cited by this paper
• Aging-Related Changes in Skeletal Muscle

  2000cited by this paper
• MTM1 mutations in X‐linked myotubular myopathy

  2000cited by this paper
• Genetic pathways that regulate ageing in model organisms

  2000cited by this paper
• Regulation of gene expression during aging.

  2000cited by this paper
• Genome-wide study of aging and oxidative stress response in Drosophila melanogaster.

  2000cited by this paper
• A family of peptidoglycan recognition proteins in the fruit fly Drosophila melanogaster.

  2000cited by this paper
• Caloric restriction and aging: an update.

  2000cited by this paper
• Gene-expression profile of the ageing brain in mice

  2000influential reference
• Sequence requirements for upregulated expression of Drosophila hsp70 transgenes during aging.

  1999cited by this paper
• Calories and aging alter gene expression for gluconeogenic, glycolytic, and nitrogen-metabolizing enzymes.

  1999cited by this paper
• Gene expression profile of aging and its retardation by caloric restriction.

  1999cited by this paper
• Aging-specific expression of Drosophila hsp22.

  1999cited by this paper
• Centrosome and microtubule instability in aging Drosophila cells.

  1999cited by this paper
• Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons

  1998cited by this paper
• Regulation of gene expression is preserved in aging Drosophila melanogaster.

  1998cited by this paper
• A peptidoglycan recognition protein in innate immunity conserved from insects to humans.

  1998cited by this paper
• LK6, a short lived protein kinase in Drosophila that can associate with microtubules and centrosomes.

  1997cited by this paper
• Oxidative Stress, Caloric Restriction, and Aging

  1996cited by this paper
• A gene mutated in X–linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast

  1996cited by this paper
• Temporal patterns of gene expression in the antenna of the adult Drosophila melanogaster.

  1995cited by this paper
• Regulation of gene expression is linked to life span in adult Drosophila.

  1995cited by this paper
• Characterization of myosin-IA and myosin-IB, two unconventional myosins associated with the Drosophila brush border cytoskeleton.

  1995cited by this paper
• Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress.

  1995cited by this paper
• From clone to mutant gene.

  1994cited by this paper
• Age‐related increase of CD45RO+ lymphocytes in physically active adults

  1993cited by this paper
• Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

  1993cited by this paper
• Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter.

  1992cited by this paper
• A 47-kDa human nuclear protein recognized by antikinetochore autoimmune sera is homologous with the protein encoded by RCC1, a gene implicated in onset of chromosome condensation.

  1990cited by this paper
• Drosophila: A laboratory handbook

  1990cited by this paper
• Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector.

  1989cited by this paper
• P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

  1989cited by this paper
• Detection in situ of genomic regulatory elements in Drosophila.

  1987cited by this paper
• A germline transformation analysis reveals flexibility in the organization of heat shock consensus elements.

  1987influential reference
• Isolation of the chicken thymidine kinase gene by plasmid rescue

  1980cited by this paper

• Distinct impacts of human co-chaperone UNC45 paralogues on Drosophila muscle development and function.

  2025cites this paper
• Simultaneous recording of spikes and calcium signals in odor-evoked responses of Drosophila antennal neurons

  2025cites this paper
• Simultaneous recording of spikes and calcium signals in odor-evoked responses of Drosophila antennal neurons

  2025cites this paper
• Dynamic changes in neuronal and glial GAL4 driver expression during Drosophila aging

  2024influential citation
• Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity

  2024cites this paper
• Aging‐affiliated post‐translational modifications of skeletal muscle myosin affect biochemical properties, myofibril structure, muscle function, and proteostasis

  2024cites this paper
• Imaging Olfactory Learning-Induced Plasticity in Vivo in the Drosophila Brain.

  2023cites this paper
• Insulin reduces the transmission potential of chikungunya virus and activates the toll pathway in Aedes aegypti mosquitoes

  2023cites this paper
• What do we mean by "aging"?: Questions and perspectives revealed by studies in Drosophila.

  2023cites this paper
• A multi‐layered network model identifies Akt1 as a common modulator of neurodegeneration

  2023cites this paper
• Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

  2023cites this paper
• Time-restricted feeding promotes muscle function through purine cycle and AMPK signaling in Drosophila obesity models

  2023cites this paper
• Juvenile and adult expression of polyglutamine expanded huntingtin produce distinct aggregate distributions in Drosophila muscle

  2023cites this paper
• Comparison of GAL80ts and Tet-off GAL80 transgenes

  2023influential citation
• A global genetic interaction network by single-cell imaging and machine learning

  2023cites this paper
• Genome-Wide Analysis in Drosophila Reveals the Genetic Basis of Variation in Age-Specific Physical Performance and Response to ACE Inhibition

  2022cites this paper
• Protocol to measure ß-galactosidase in Drosophila extracts using a CPRG assay

  2022cites this paper
• Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy: Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

  2022cites this paper
• Drosophila Innate Immunity Involves Multiple Signaling Pathways and Coordinated Communication Between Different Tissues

  2022cites this paper
• Altered stability of nuclear lamin-B marks the onset of aging in male Drosophila

  2022influential citation
• A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging

  2021cites this paper
• Male Age and Wolbachia Dynamics: Investigating How Fast and Why Bacterial Densities and Cytoplasmic Incompatibility Strengths Vary

  2021cites this paper
• Mapping Genetic Variants Associated with Dynamic Protein Abundance in Haploid Yeast

  2021cites this paper
• Functional conservation in genes and pathways linking ageing and immunity

  2021cites this paper
• Male Age and Wolbachia Dynamics: Investigating How Fast and Why Bacterial Densities and Cytoplasmic Incompatibility Strengths Vary

  2021cites this paper
• The Impact of Age on Response to Infection in Drosophila

  2021cites this paper
• Versatile Method to measure locomotion in adult Drosophila.

  2020cites this paper
• The Phosphatase CSW Controls Life Span by Insulin Signaling and Metabolism Throughout Adult Life in Drosophila

  2020cites this paper
• Modelling aging

  2020cites this paper
• Versatile Method to measure locomotion

  2020cites this paper
• Identification of hub genes, key pathways, and therapeutic agents in Hutchinson–Gilford Progeria syndrome using bioinformatics analysis

  2020cites this paper
• Dysregulation of antimicrobial peptide expression distinguishes Alzheimer’s disease from normal aging

  2020cites this paper
• The potential for complex computational models of aging.

  2020cites this paper
• Odorant binding proteins promote flight activity in the migratory insect, Helicoverpa armigera

  2020cites this paper
• Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster.

  2019cites this paper
• The impact of Megf10/Drpr gain‐of‐function on muscle development in Drosophila

  2019cites this paper
• MicroRNA miR‐252 targets mbt to control the developmental growth of Drosophila

  2019cites this paper
• New insights on Drosophila antimicrobial peptide function in host defense and beyond.

  2019cites this paper
• Expression of Heat Shock Protein 70 Is Insufficient To Extend Drosophila melanogaster Longevity

  2019cites this paper
• The Epigenetics of Aging in Invertebrates

  2019cites this paper
• Lisinopril preserves physical resilience and extends life span in a genotype-specific manner in Drosophila melanogaster.

  2019cites this paper
• EDTP/MTMR14: A novel target for improved survivorship to prolonged anoxia and cellular protein aggregates.

  2019cites this paper
• Generating Cell-Specific CRISPR Knockouts to Investigate the Role of Neuropeptide Receptors on Drosophila Behavior

  2018cites this paper
• Healthy Aging and Epigenetic Drugs for Diabetes and Obesity

  2018cites this paper
• Drosophila melanogaster and the social environment : ageing, immunity and the microbiome

  2018influential citation
• The interplay between immunity and aging in Drosophila

  2018cites this paper
• Evolution of longevity improves immunity in Drosophila

  2018cites this paper
• Drosophila egg-derived tyrosine phosphatase (EDTP): a novel target for improved survivorship to prolonged anoxia and cellular protein aggregates

  2018cites this paper
• Unraveling the Molecular Mechanism of Immunosenescence in Drosophila

  2018cites this paper
• Functional genomics of ageing and its modulation by diet

  2017cites this paper
• Tissue-specific downregulation of EDTP suppresses polyglutamine protein aggregates and extends lifespan in Drosophila

  2017cites this paper
• Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants

  2017cites this paper
• Regulating the UAS/GAL4 system in adult Drosophila with Tet-off GAL80 transgenes

  2017influential citation
• HDAC inhibitors: A new promising drug class in anti-aging research.

  2017cites this paper
• Epigenetic Regulation of Longevity in Insects

  2017cites this paper
• miR-34 Modulates Innate Immunity and Ecdysone Signaling in Drosophila

  2016cites this paper
• Transgenic Drosophila for Investigating DUX4 and FRG1, Two Genes Associated with Facioscapulohumeral Muscular Dystrophy (FSHD)

  2016cites this paper
• Anti-aging pharmacology: Promises and pitfalls.

  2016cites this paper
• Longevity-modulating effects of symbiosis: insights from Drosophila–Wolbachia interaction

  2016cites this paper
• The Insulin-Like Proteins dILPs-2/5 Determine Diapause Inducibility in Drosophila

  2016cites this paper
• Analysis of the effects of mitochondrial mutator system in Drosophila melanogaster

  2015cites this paper
• TOWARDS THE DEVELOPMENT OF TRANSGENIC REPORTER LINES FOR ASSESSING AND CHARACTERIZING A LAC-REGULATED UAS- GAL4 SYSTEM

  2015cites this paper
• Effect of Wolbachia Infection on Aging and Longevity-Associated Genes in Drosophila

  2015cites this paper
• Injuries can prolong lifespan in Drosophila melanogaster males

  2015cites this paper
• The Formin Diaphanous Regulates Myoblast Fusion through Actin Polymerization and Arp2/3 Regulation

  2015cites this paper
• Clueless, a protein required for mitochondrial function, interacts with the PINK1-Parkin complex in Drosophila

  2015cites this paper
• Life Extension in Drosophila by Histone Deacetylase Inhibitors

  2015cites this paper
• GENETIC EVIDENCE FOR DIFFERENTIAL ACTIVITIES OF Goα ISOFORMS IN DROSOPHILA MELANOGASTER

  2014influential citation
• Bug22 influences cilium morphology and the post-translational modification of ciliary microtubules

  2014cites this paper
• Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia.

  2014cites this paper
• Egg-derived tyrosine phosphatase as a potential biomarker for muscle ageing and degeneration in Drosophila melanogaster.

  2014cites this paper
• The Drosophila Imd Signaling Pathway

  2014cites this paper
• Ageing and the cellular immune response in adult Drosophila melanogaster

  2014influential citation
• The main actors involved in extending the invertebrate life span

  2014cites this paper
• The dilp2/5 genes control diapause inducibility

  2013cites this paper
• Phosphoinositides: tiny lipids with giant impact on cell regulation.

  2013cites this paper
• Immunosenescence in vertebrates and invertebrates

  2013cites this paper
• Neurodegeneration in Drop-Dead Mutant Drosophila melanogaster Is Associated with the Respiratory System but Not with Hypoxia

  2013influential citation
• Molecular Mechanisms of Aging and Immune System Regulation in Drosophila

  2012cites this paper
• Morpho-functional changes of fat body in bacteria fed Drosophila melanogaster strains

  2012cites this paper
• Histone recognition and nuclear receptor co-activator functions of Drosophila Cara Mitad, a homolog of the N-terminal portion of mammalian MLL2 and MLL3

  2012cites this paper
• Methionine sulfoxide reductase B in the endoplasmic reticulum is critical for stress resistance and aging in Drosophila.

  2012cites this paper
• Healthy Aging – Insights from Drosophila

  2012cites this paper
• Epigenetic drugs: a novel anti-aging strategy?

  2012cites this paper
• Differential requirements for Myocyte Enhancer Factor-2 during adult myogenesis in Drosophila.

  2012cites this paper
• Senescence of the cellular immune response in Drosophila melanogaster.

  2011cites this paper
• A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila.

  2011cites this paper
• The impact of aging on genome-wide patterns of gene expression in the African malaria vector Anopheles gambiae

  2010cites this paper
• Mechanisms Associated with Aging and Age-Related Disease in Drosophila

  2010cites this paper
• Genome-Wide Patterns of Gene Expression during Aging in the African Malaria Vector Anopheles gambiae

  2010cites this paper
• Peristalsis in the junction region of the Drosophila larval midgut is modulated by DH31 expressing enteroendocrine cells

  2010cites this paper
• Mechanisms Associated with Aging and Age- Related Disease in Drosophila

  2010cites this paper
• The role of Drosophila Lamin C in muscle function and gene expression

  2010cites this paper
• Adverse interactions between micro-RNAs and target genes from different species

  2010cites this paper
• Neuronal susceptibility to GRIM in Drosophila melanogaster measures the rate of genetic changes that scale to lifespan.

  2009influential citation
• Crossregulation of Insulin signalling and innate immunity

  2009cites this paper
• Sod2 knockdown in the musculature has whole-organism consequences in Drosophila.

  2009cites this paper
• Establishing a role for specific nutrients in Drosophila dietary restriction

  2009cites this paper
• A forward genetic screen in Drosophila implicates insulin signaling in age-related locomotor impairment.

  2009cites this paper
• Role of Apolipoprotein D and its homologs, in normal and pathological aging, in Drosophila melanogaster

  2009cites this paper