Iron deficiency is common in patients with heart failure and associated with a poor cardiac function and higher mortality. How iron deficiency impairs cardiac function on a cellular level in the human setting is unknown. This study aims to determine the direct effects of iron deficiency and iron repletion on human cardiomyocytes.
Iron deficiency impairs contractility of human cardiomyocytes through decreased mitochondrial function
M. Hoes,N. Grote Beverborg,J. D. Kijlstra,J. Kuipers,D. Swinkels,B. Giepmans,R. Rodenburg,D. V. van Veldhuisen,R. D. de Boer,P. van der Meer
Published 2018 in European Journal of Heart Failure
ABSTRACT
PUBLICATION RECORD
- Publication year
2018
- Venue
European Journal of Heart Failure
- Publication date
2018-02-27
- Fields of study
Biology, Medicine, Environmental Science
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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