Gonadotropin-releasing hormone agonist and danazol normalize aromatase cytochrome P450 expression in eutopic endometrium from women with endometriosis, adenomyosis, or leiomyomas.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Fertility and Sterility

• Publication date

  2003-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0015-0282(02)04813-6PMID 12620485
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium.

  2000cited by this paper
• Detection of aromatase cytochrome P-450 in endometrial biopsy specimens as a diagnostic test for endometriosis.

  1999cited by this paper
• Stimulation of aromatase P450 promoter (II) activity in endometriosis and its inhibition in endometrium are regulated by competitive binding of steroidogenic factor-1 and chicken ovalbumin upstream promoter transcription factor to the same cis-acting element.

  1999cited by this paper
• Apoptosis and Ki-67 expression in adenomyotic lesions and in the corresponding eutopic endometrium.

  1999cited by this paper
• Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium.

  1997cited by this paper
• Aromatase expression in endometriosis.

  1996cited by this paper
• Expression of the CYP19 gene and its product aromatase cytochrome P450 in human uterine leiomyoma tissues and cells in culture.

  1994cited by this paper
• CYP19 (aromatase cytochrome P450) gene expression in human malignant endometrial tumors.

  1994cited by this paper
• Stromal spindle cells contain aromatase in human breast tumors.

  1994cited by this paper
• Effect of danazol in vitro and in vivo on monocyte-mediated enhancement of endometrial cell proliferation in women with endometriosis.

  1994cited by this paper
• Estrogen and progesterone receptors in endometriotic tissue and endometrium: comparison according to localization and recurrence.

  1993cited by this paper
• Evidence for estrogen synthesis in adenomyotic tissues.

  1993cited by this paper
• Direct effects of medroxyprogesterone acetate, danazol, and leuprolide acetate on endometrial stromal cell proliferation in vitro.

  1992cited by this paper
• Danazol. A synthetic steroid with diverse biologic effects.

  1990cited by this paper
• Fibroid and myometrial steroid receptors in women treated with gonadotropin-releasing hormone agonist leuprolide acetate.

  1990cited by this paper
• Danazol. A synthetic steroid with diverse biologic effects.

  1990cited by this paper
• Danazol Suppresses the Production of Interleukin‐1β and Tumor Necrosis Factor by Human Monocytes

  1990cited by this paper
• Estrogen biosynthesis in human uterine adenomyosis.

  1989cited by this paper
• Immunohistochemical analysis of estrogen and progesterone receptors in endometriosis: comparison with normal endometrium during the menstrual cycle and the effect of medical therapy.

  1989cited by this paper
• An enzyme-linked immunosorbent assay for quantitation of aromatase cytochrome P-450.

  1989cited by this paper
• Danazol inhibits steroidogenesis by the human ovary in vivo.

  1986cited by this paper
• Aromatization of androstenedione by normal and neoplastic endometrium of the uterus.

  1985cited by this paper
• Effect of Aminoglutethimide on Androstenedione Aromatase Activity in Human Uterine Leiomyoma

  1985cited by this paper
• Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies.

  1985cited by this paper
• Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

  1984cited by this paper
• Danazol: endocrine pharmacology and therapeutic applications.

  1981cited by this paper
• Dating the endometrial biopsy.

  1950cited by this paper

• Effect of extended hormonal suppression in patients with adenomyosis undergoing embryo transfer.

  2026cites this paper
• Hormone receptor profile of ectopic and eutopic endometrium in adenomyosis: a systematic review

  2025cites this paper
• Evaluating the Impact of Long-Term GnRH Agonist Therapy on Pregnancy Outcomes in Endometriosis-Associated Implantation Failure and Pregnancy Loss

  2024cites this paper
• Hormonal Therapies before in vitro fertilization in women with endometriosis: The Minotaur's Labyrinth and the Ariadne's Thread.

  2024cites this paper
• Medical Management of Ovarian Endometriomas

  2023cites this paper
• Impact of adenomyosis on IVF outcomes in women undergoing donor oocyte transfers: a prospective observational study.

  2023cites this paper
• The role of the junctional zone in the management of adenomyosis with infertility

  2023cites this paper
• The Present and the Future of Medical Therapies for Adenomyosis: A Narrative Review

  2023cites this paper
• A View on Uterine Leiomyoma Genesis through the Prism of Genetic, Epigenetic and Cellular Heterogeneity

  2023cites this paper
• Comparison of pregnancy outcomes between GnRH antagonist protocol with freeze-all strategy and long-acting GnRH agonist protocol in women with adenomyosis undergoing IVF/ICSI: a propensity-score matching analysis

  2022cites this paper
• Androgen Signaling in Uterine Diseases: New Insights and New Targets

  2022cites this paper
• Is intracrinology of endometriosis relevant in clinical practice? A systematic review on estrogen metabolism

  2022cites this paper
• The Potential Relationship Between Environmental Endocrine Disruptor Exposure and the Development of Endometriosis and Adenomyosis

  2022cites this paper
• Operative Management of Adenomyosis

  2021cites this paper
• A Validated Model for Individualized Prediction of Live Birth in Patients With Adenomyosis Undergoing Frozen–Thawed Embryo Transfer

  2021cites this paper
• Impact of Gonadotropin-Releasing Hormone Agonist Pre-treatment on the Cumulative Live Birth Rate in Infertile Women With Adenomyosis Treated With IVF/ICSI: A Retrospective Cohort Study

  2020cites this paper
• Gonadotropin-releasing hormone analogs: mechanisms of action and clinical applications in female reproduction.

  2020cites this paper
• Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus.

  2019cites this paper
• Systematic review and meta‐analysis of adverse pregnancy outcomes after uterine adenomyosis

  2019cites this paper
• High-intensity focused ultrasound (HIFU) combined with gonadotropin-releasing hormone analogs (GnRHa) and levonorgestrel-releasing intrauterine system (LNG-IUS) for adenomyosis: a case series with long-term follow up

  2019cites this paper
• Agonistas de la hormona liberadora de gonadotropinas (GnRH)

  2019cites this paper
• Role of medical therapy in the management of uterine adenomyosis.

  2018cites this paper
• Treatment options and reproductive outcome for adenomyosis-associated infertility

  2018cites this paper
• Agonistes de la « gonadotropin-releasing hormone » (GnRH)

  2018cites this paper
• LncRNA882 regulates leukemia inhibitory factor (LIF) by sponging miR‐15b in the endometrial epithelium cells of dairy goat

  2018cites this paper
• Investigational Medical Therapies for Endometriosis: Current Data and Future Trends

  2017cites this paper
• Activin A Stimulates Aromatase via the ALK4-Smad Pathway in Endometriosis

  2016cites this paper
• The Impact of Adenomyosis on Women's Fertility

  2016cites this paper
• Adenomyosis: A Clinical Review of a Challenging Gynecologic Condition.

  2016cites this paper
• A novel laparoscopic surgical technique for severe adenomyoma.

  2016cites this paper
• Adenomyosis: What the Patient Needs.

  2016cites this paper
• Current and Future Medical Treatment of Adenomyosis

  2016cites this paper
• Current Treatment for Adenomyosis

  2016cites this paper
• Dental management in pregnancy: recent trends.

  2016cites this paper
• Aromatase Inhibitors for Endometriosis-Associated Infertility; Do We Have Sufficient Evidence?

  2016influential citation
• Human Adenomyosis Endometrium Stromal Cells Secreting More Nerve Growth Factor

  2015cites this paper
• Adénomyose et implantation : mise au point

  2015cites this paper
• Treatment of pain associated with deep endometriosis: alternatives and evidence.

  2015cites this paper
• Adenomyosis: What is New?

  2015cites this paper
• ART and uterine pathology: how relevant is the maternal side for implantation?

  2015cites this paper
• [An update on adenomyosis and implantation].

  2015cites this paper
• Surface plasmon resonance imaging biosensors for aromatase based on a potent inhibitor and a specific antibody: Sensor development and application for biological material

  2014cites this paper
• Association of aromatase (TTTA)n repeat polymorphisms with central precocious puberty in girls

  2014cites this paper
• Radiological Interventions in Obstetrics and Gynaecology

  2014cites this paper
• An update on the pharmacological management of adenomyosis

  2014cites this paper
• Structural and molecular features of the endomyometrium in endometriosis and adenomyosis.

  2014cites this paper
• Differential expression of steroidogenic enzymes according to endometriosis type.

  2013cites this paper
• The Medical Treatment of Uterine Fibroids

  2013cites this paper
• Assessing the efficacy of aspiration and ethanol injection in recurrent endometrioma before IVF cycle: A randomized clinical trial

  2013cites this paper
• The Expression Status of G Protein-Coupled Receptor GPR30 Is Associated with the Clinical Characteristics of Endometriosis

  2013cites this paper
• Steroid synthesis by Taenia crassiceps WFU cysticerci is regulated by enzyme inhibitors.

  2013cites this paper
• Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis

  2013cites this paper
• Benign Uterine Diseases

  2013cites this paper
• The use of aromatase inhibitors in in vitro fertilization.

  2012cites this paper
• Aromatase inhibitors or gonadotropin‐releasing hormone agonists for the management of uterine adenomyosis: a randomized controlled trial

  2012cites this paper
• Aromatase (CYP19) gene variants influence ovarian response to standard gonadotrophin stimulation

  2012cites this paper
• Endometrial receptivity defects during IVF cycles with and without letrozole.

  2012cites this paper
• Role of Inflammation and Aromatase Expression in the Eutopic Endometrium and its Relationship with the Development of Endometriosis

  2012cites this paper
• The Endometrium in Adenomyosis

  2012cites this paper
• Adenomyosis and infertility.

  2012cites this paper
• Progestogen only versus combined oral contraceptive pills for fibroid related heavy menstrual bleeding

  2012cites this paper
• International consensus and practical guidelines on the gynecologic and obstetric management of female patients with hereditary angioedema caused by C1 inhibitor deficiency.

  2012cites this paper
• Is abnormal eutopic endometrium the cause of endometriosis? The role of eutopic endometrium in pathogenesis of endometriosis

  2011cites this paper
• steve bAccumulation of nerve growth factor and its receptors in the uterus and dorsal root ganglia in a mouse model of adenomyosis

  2011cites this paper
• Are aromatase inhibitors effective in endometriosis treatment?

  2011cites this paper
• Infertility and Adenomyosis

  2011cites this paper
• Adenomyosis: review of the literature.

  2011cites this paper
• The effect of adenomyosis on in vitro fertilisation and intra-cytoplasmic sperm injection treatment outcome.

  2011cites this paper
• The aromatase expression in myomas and myometriums of women in reproduction and perimenopausal age.

  2010cites this paper
• Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy.

  2010cites this paper
• Molecular profiling of human endometrium and endometriosis

  2010cites this paper
• Is aromatase expression in the endometrium the cause of endometriosis and related infertility?

  2009influential citation
• Absence of aromatase protein and mRNA expression in endometriosis.

  2009influential citation
• Gonadotropin-Releasing Hormone Agonist Reduces Aromatase Cytochrome P450 and Cyclooxygenase-2 in Ovarian Endometrioma and Eutopic Endometrium of Patients with Endometriosis

  2009cites this paper
• RETRACTED: The Expression and Ovarian Steroid Regulation of Endometrial Micro-RNAs

  2008cites this paper
• Maintenance therapy involving a tapering dose of danazol or mid/low doses of oral contraceptive after gonadotropin-releasing hormone agonist treatment for endometriosis-associated pelvic pain.

  2008cites this paper
• Non-contraceptive health benefits of oral contraceptives

  2008cites this paper
• The effect of oral contraceptives on aromatase expression in the eutopic endometrium of patients with endometriosis

  2008cites this paper
• Clinical factors affecting endometrial receptiveness in oocyte donation cycles.

  2008cites this paper
• Concomitant treatment of severe uterine adenomyosis in a premenopausal woman with an aromatase inhibitor and a gonadotropin-releasing hormone agonist.

  2007cites this paper
• Gonadotropin-releasing hormone agonist treatments reduce aromatase and cyclooxygenase-2 in ovarian endometrioma and eutopic endometium in women with endometriosis

  2007cites this paper
• Lack of dehydroepiandrosterone in type I and II hereditary angioedema and role of danazol in steroid hormone conversion

  2007cites this paper
• Aromatase expression in the eutopic endometrium of myomatous uteri: The influence of the menstrual cycle and oral contraceptive use

  2007influential citation
• Expression und Regulation von Enzymen des Östrogenmetabolismus in humanen Endometriumläsionen kultiviert in der Nacktmaus

  2007cites this paper
• Danazol inhibits aromatase activity of endometriosis-derived stromal cells by a competitive mechanism.

  2006cites this paper
• Future directions in myoma research.

  2006cites this paper
• GnRH analogs: options for endometriosis-associated pain treatment.

  2006cites this paper
• Aromatase and cyclooxygenase-2 expression in endometrial polyps during the menstrual cycle

  2006cites this paper
• UTERUS Aromatase and cyclooxygenase-2 expression in endometrial polyps during the menstrual cycle

  2006cites this paper
• Effect of the menstrual cycle and oral contraceptives on aromatase and cyclooxygenase-2 expression in adenomyosis

  2006cites this paper
• GnRH agonist and antagonist: Options for endometriosis pain treatment

  2006cites this paper
• Aplicação de dispositivo intra-uterino liberador de levonorgestrel, previamente a ciclos de fertilização in vitro, nas portadoras de adenomiose

  2006cites this paper
• HISTOPATOLOGIA DA ADENOMIOSE EM VACAS ABATIDAS NO NORTE FLUMINENSE

  2006cites this paper
• Expression of aromatase (P450 aromatase/CYP19) in peritoneal and ovarian endometriotic tissues and deep endometriotic (adenomyotic) nodules of the rectovaginal septum.

  2006cites this paper
• Adenomyosis: the pathophysiology of an oestrogen-dependent disease.

  2006cites this paper
• Decreased suppression of interleukin-6 after treatment with medroxyprogesterone acetate and danazol in endometrial stromal cells of women with adenomyosis.

  2006cites this paper
• Indications des analogues de la GnRH en pré- et postchirurgie pour endométriose

  2005cites this paper
• Aromatase inhibitors and cyclooxygenase-2 (COX-2) inhibitors in endometriosis: new questions--old answers?

  2005cites this paper
• [Drug treatments for uterine fibroma: rationale].

  2005cites this paper
• [Indications of GnRH analogues before and after surgery for endometriosis].

  2005cites this paper