NG-nitro-L-arginine (N5-[imino(nitroamino)methyl]-L-ornithine) impairs endothelium-dependent dilations by inhibiting cytosolic nitric oxide synthesis from l-arginine

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/BF00195071PMID 2314480
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• L-arginine-dependent nitric oxide formation and nitrite release in bone marrow-derived macrophages stimulated with bacterial lipopeptide and lipopolysaccharide.

  1990cited by this paper
• Modulation of the Vasodilator Action of SIN‐1 by the Endothelium

  1989cited by this paper
• A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells.

  1989cited by this paper
• A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation

  1989cited by this paper
• Generation of nitric oxide by human neutrophils.

  1989cited by this paper
• Identification of arginine as a precursor of endothelium-derived relaxing factor.

  1988cited by this paper
• Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

  1988cited by this paper
• SHORT COMMUNICATION: Cytokines Induce an L‐Arginine‐Dependent Effector System in Nonmacrophage Cells

  1988cited by this paper
• L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation.

  1988cited by this paper
• Arginine is a physiological precursor of endothelium-derived nitric oxide.

  1988cited by this paper
• Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.

  1988cited by this paper
• Is arginine a physiological precursor of endothelium-derived nitric oxide?

  1988cited by this paper
• Characterization of vascular relaxant factor released from cultured endothelial cells.

  1987cited by this paper
• Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide.

  1987cited by this paper
• Macrophage synthesis of nitrite, nitrate, and N-nitrosamines: precursors and role of the respiratory burst.

  1987influential reference
• Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

  1987cited by this paper
• Stimulation of soluble guanylate cyclase by endothelium-derived relaxing factor from cultured endothelial cells.

  1987cited by this paper
• The role of prostaglandins in the endothelium-mediated vasodilatory response to hypoxia

  1984cited by this paper
• Some Statistical Methods Useful in Circulation Research

  1980cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper

• A bibliometric study of the most-cited research articles and reviews in Naunyn–Schmiedeberg’s Archives of Pharmacology (1969–2024)

  2025cites this paper
• The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms

  2022cites this paper
• Targeting VE-PTP phosphatase protects the kidney from diabetic injury

  2019cites this paper
• Blast exposure elicits blood-brain barrier disruption and repair mediated by tight junction integrity and nitric oxide dependent processes

  2018cites this paper
• Parkia speciosa empty pod prevents hypertension and cardiac damage in rats given N(G)-nitro-l-arginine methyl ester.

  2017cites this paper
• veinsrelaxation of newborn ovine pulmonary Role of protein kinase G in nitric oxide- and

  2015cites this paper
• Centre for Human Genetics Gene expression differences in cardiovascular disease

  2015cites this paper
• relaxation of rabbit pulmonary arteries Developmental change in magnesium sulfate-induced

  2015cites this paper
• Crucial Role for Neuronal Nitric Oxide Synthase in Early Microcirculatory Derangement and Recipient Survival following Murine Pancreas Transplantation

  2014cites this paper
• Protective effects of 17beta-estradiol on post-ischemic cardiac dysfunction and norepinephrine overflow through the non-genomic estrogen receptor/nitric oxide-mediated pathway in the rat heart.

  2013cites this paper
• Ultraviolet A irradiation on human skin : nitric oxide mediated cardiovascular responses

  2012cites this paper
• GASTROINTESTINAL MOTILITY, PROKINETIC BENZAMIDES AND SEROTONIN

  2012cites this paper
• The effect of nitric oxide inhibitors and s-nitrosothiols on hemodynamic parameters in an animal model

  2011influential citation
• The effect of nitric oxide inhibitors and s-nitrosothiols on hemodynamic parameters in an animal model

  2011cites this paper
• Regulation of the pulmonary circulation in the fetus and newborn.

  2010cites this paper
• Cerebral Blood Flow Regulation by Nitric Oxide: Recent Advances

  2009cites this paper
• Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders

  2008cites this paper
• Muscarinic receptor M1 and phosphodiesterase 1 are key determinants in pulmonary vascular dysfunction following perinatal hypoxia in mice.

  2008cites this paper
• Pelvic Nerve Stimulation Evokes Nitric Oxide Mediated Distal Rectal Relaxation in Pigs

  2008cites this paper
• Enhanced expression of contractile endothelin ET(B) receptors in rat coronary artery after organ culture.

  2008cites this paper
• Dual response of cerebrocortical F blood flow and arterial blood pressure to transient CO : ,

  2008cites this paper
• Protein kinase G regulates the basal tension and plays a major role in nitrovasodilator‐induced relaxation of porcine coronary veins

  2007cites this paper
• Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia.

  2007cites this paper
• Perinatal hypoxia triggers alterations in K+ channels of adult pulmonary artery smooth muscle cells.

  2007cites this paper
• cGMP-dependent protein kinase in regulation of basal tone and in nitroglycerin- and nitric-oxide-induced relaxation in porcine coronary artery

  2007cites this paper
• Role of Membrane Potential in Endothelium-Dependent Relaxation of Isolated Mouse Main Pulmonary Artery

  2006cites this paper
• Hypoxia-induced reactive oxygen species downregulate ETB receptor-mediated contraction of rat pulmonary arteries.

  2006cites this paper
• Balloon Injury and Interleukin-1 Induce Nitric Oxide Synthase Activit in Rat Carotid Arteries

  2005cites this paper
• Bovine Mesenteric Artery

  2005cites this paper
• Enzymic and nonenzymic release of NO accounts for the vasodilator activity of the metabolites of CAS 936, a novel long-acting sydnonimine derivative

  2004cites this paper
• Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-l-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts

  2004influential citation
• Nitric oxide in physiology and pathology

  2004cites this paper
• Endothelium-dependent contractions to NG-nitro-L-arginine methyl ester in the porcine isolated splenic artery are sensitive to cyclooxygenase and lipoxygenase inhibitors

  2004cites this paper
• The Pharmacology of Nitric Oxide in the Peripheral Nervous System of Blood Vessels

  2003cites this paper
• Novel insight into the mechanisms involved in the regulation of the m1 muscarinic receptor, iNOS and nNOS mRNA levels.

  2003cites this paper
• Effects of L-arginine and sodium nitroprusside on the spontaneous contractility of human non-pregnant uterus.

  2003cites this paper
• Actions of NO donors and endogenous nitrergic transmitter on the longitudinal muscle of rat ileum in vitro: mechanisms involved.

  2001cites this paper
• Nitric oxide modulates evoked catecholamine release from canine adrenal medulla.

  2001cites this paper
• Endogenous nitric oxide‐mediated relaxation and nitrinergic innervation in the rabbit prostate: The changes with aging

  2001cites this paper
• Effects of aminoguanidine and N(omega)-nitro-L-arginine methyl ester on vascular hyporeactivity induced by endotoxaemia.

  2001cites this paper
• Maturational Changes in Endothelium-Derived Nitric Oxide-Mediated Relaxation of Ovine Pulmonary Arteries

  2000cites this paper
• Intracellular Signals Coupled to Muscarinic Acetylcholine Receptor Activation in Cerebral Frontal Cortex from Hypoxic Mice

  2000cites this paper
• Thromboxane A2 modulates cyclic AMP relaxation and production in human internal mammary artery

  2000cites this paper
• Involvement of the endogenous nitric oxide signalling system in bradykinin receptor activation in rat submandibular salivary gland.

  2000cites this paper
• Brain blood flow during hypercapnia in fish: no role of nitric oxide.

  2000cites this paper
• Thromboxane A(2) modulates cyclic AMP relaxation and production in human internal mammary artery.

  2000cites this paper
• Functional antagonism between nitric oxide and ATP in the motor responses of guinea-pig ileum.

  2000cites this paper
• L‐NAME inhibits Mg2+‐induced rat aortic relaxation in the absence of endothelium

  1999cites this paper
• Bilateral kidney ligation abolishes pressor response to N(G)-nitro-D-arginine.

  1999cites this paper
• Endothelium is required in the vascular spasm induced by tetraethylammonium and endothelin‐1 in guinea‐pig aorta

  1999cites this paper
• NO mediates postjunctional inhibitory effect of neurogenic ACh in guinea pig small intestinal microcirculation.

  1999cites this paper
• Role of protein kinase G in nitric oxide- and cGMP-induced relaxation of newborn ovine pulmonary veins.

  1999cites this paper
• Differences in aortic response to vasoactive stimuli in Japanese and Lyon rats. The role of hypertension.

  1999cites this paper
• Developmental change in magnesium sulfate-induced relaxation of rabbit pulmonary arteries.

  1999cites this paper
• Strain differences of hypertension induced by dietary NG-nitro-L-arginine in normotensive rats.

  1999cites this paper
• Augmentation of diabetes-associated renal hyperfiltration and nitric oxide production by pregnancy in rats.

  1999cites this paper
• Characteristics of heterogeneity in the expression of vasoconstriction in response to N(G)-monomethyl-L-arginine in isolated canine arteries.

  1999cites this paper
• Non-adrenergic, non-cholinergic regulation of stone-diseased and stone-free human gallbladders.

  1999cites this paper
• Enhanced activity of carotid body chemoreceptors in rabbits with heart failure: role of nitric oxide.

  1999cites this paper
• A non-nitrergic smooth muscle relaxant factor released from rat urinary bladder by muscarinic receptor stimulation.

  1999cites this paper
• Alterations of the vascular and the myocardial guanylate cyclase/cGMP-system induced by long-term hypertension in rats.

  1998cites this paper
• ACETYLCHOLINE‐INDUCED SYSTEMIC VASODILATION RESISTANT TO NG‐NITRO‐L‐ARGININE IN ANAESTHETIZED RATS

  1998cites this paper
• Effect of selective phosphodiesterase inhibitors on response of ovine pulmonary arteries to prostaglandin E2.

  1998cites this paper
• Lafutidine-induced stimulation of mucin biosynthesis mediated by nitric oxide is limited to the surface mucous cells of rat gastric oxyntic mucosa.

  1998cites this paper
• Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats.

  1998cites this paper
• Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitric oxide synthase inhibition.

  1998cites this paper
• Developmental change in isoproterenol-mediated relaxation of pulmonary veins of fetal and newborn lambs.

  1998cites this paper
• Contribution of nitric oxide and substance P to nonadrenergic, noncholinergic transmission in the guinea pig ileum.

  1998cites this paper
• Characterization of NS 2028 as a specific inhibitor of soluble guanylyl cyclase

  1998cites this paper
• Role of nitric oxide in cardiac beta-adrenoceptor-inotropic response.

  1998cites this paper
• Involvement of endogenous nitric oxide signalling system in brain muscarinic acetylcholine receptor activation

  1998cites this paper
• Characterization of Endothelium- Dependent Relaxation in Guinea Pig Basilar Artery – Effect of Hypoxia and Role of Cytochrome P450 Mono-Oxygenase

  1998cites this paper
• Inhibition of nitric oxide synthase and soluble guanylate cyclase induces cardiodepressive effects in normal rat hearts.

  1997cites this paper
• [Nonadrenergic noncholinergic regulation of gallstone containing and gallstone free human gallbladders].

  1997cites this paper
• Structural requirements for roxatidine in the stimulant effect of rat gastric mucin synthesis and the participation of nitric oxide in this mechanism

  1997cites this paper
• Polymerized hemoglobin restores cardiovascular and kidney function in endotoxin-induced shock in the rat.

  1997cites this paper
• Antenatal Betamethasone Therapy Augments Isoproterenol and Prostaglandin E2-Mediated Relaxation of Preterm Ovine Pulmonary Veins

  1997cites this paper
• Nitric Oxide Synthase in Spontaneously Hypertensive Rats.

  1997cites this paper
• Aminoguanidine reverses aortic hyporeactivity to noradrenaline in portal vein-ligated rats.

  1997cites this paper
• Increased myogenic tone and diminished responsiveness to ATP-sensitive K+ channel openers in cerebral arteries from diabetic rats.

  1997cites this paper
• Tetrahydrobiopterin synthesis inhibitors induce nitric oxide synthesis in rat aorta.

  1997cites this paper
• Role of nitric oxide and nitric oxide-independent relaxing factor in contraction and relaxation of rabbit blood vessels.

  1997cites this paper
• Biological activation of NG-nitro-D-arginine by kidney homogenate

  1997cites this paper
• [Anesthetics and nitric oxide. Interactions and their importance for anesthesia].

  1997cites this paper
• Mediation of endothelium-dependent relaxation: different response patterns in rat and rabbit basilar artery.

  1997cites this paper
• Comparative aspects on nitric oxide in brain and its role as a cerebral vasodilator.

  1997cites this paper
• Inhibitory effect of a fullerene derivative, monomalonic acid C60, on nitric oxide-dependent relaxation of aortic smooth muscle.

  1997cites this paper
• The mechanism of the relaxing effect of ascorbic acid in guinea pig isolated tracheal muscle.

  1997cites this paper
• Nitric oxide-dependent and -independent norepinephrine release in rat mesenteric arteries.

  1997cites this paper
• Participation of nitric oxide signaling system in the cardiac muscarinic cholinergic effect of human chagasic IgG.

  1997cites this paper
• Effects of inhibition of nitric oxide synthesis and of hypercapnia on blood pressure and brain blood flow in the turtle.

  1997cites this paper
• Demonstration of NADPH-diaphorase (NO-synthase) in sebaceous glands of the mammalian integument, with remarks on the glandular capillary net.

  1996cites this paper
• The role of nitric oxide in ischaemia reperfusion injury in the rabbit heart.

  1996cites this paper
• Regulation of interleukin-1-beta-stimulated inducible nitric oxide synthase expression in cultured vascular smooth muscle cells by hemostatic proteins.

  1996cites this paper
• Endothelium-dependent relaxation counteracting the contractile action of endothelin-1 is partly due to ETB receptor activation

  1996cites this paper
• Involvement of nitric oxide in inhibitory neuromuscular transmission in equine jejunum.

  1996cites this paper
• Endothelium-dependent relaxation of rat aorta to a histamine H3 agonist is reduced by inhibitors of nitric oxide synthase, guanylate cyclase and Na+,K+-ATPase

  1996cites this paper
• Pharmacological characterization of 5-hydroxytryptamine-induced motor activity (in vitro) in the guinea pig gastric antrum and corpus.

  1996cites this paper
• A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue.

  1996cites this paper
• Facilitation of the vasorelaxant action of calcium antagonists by basal nitric oxide in depolarized artery

  1996cites this paper