Involvement of CYP1B1 in interferon γ‐induced alterations of epithelial barrier integrity

No abstract is available for this paper.

• Publication year

  2018

• Venue

  British Journal of Pharmacology

• Publication date

  2018-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1111/bph.14122PMID 29232759PMCID PMC5825299
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Involvement of CYP1B1 in interferon γ‐induced alterations of epithelial barrier integrity

  2018cited by this paper
• THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Enzymes

  2017cited by this paper
• THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview

  2017cited by this paper
• CYP1B1 inhibition attenuates doxorubicin-induced cardiotoxicity through a mid-chain HETEs-dependent mechanism.

  2016cited by this paper
• Defects in 15-HETE Production and Control of Epithelial Permeability by Human Enteric Glial Cells From Patients With Crohn's Disease.

  2016cited by this paper
• Repurposing Resveratrol and Fluconazole To Modulate Human Cytochrome P450-Mediated Arachidonic Acid Metabolism.

  2016cited by this paper
• Investigating the Responses of Human Epithelial Cells to Predatory Bacteria

  2016cited by this paper
• Experimental design and analysis and their reporting: new guidance for publication in BJP

  2015cited by this paper
• The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands

  2015cited by this paper
• Hypoxia interferes with aryl hydrocarbon receptor pathway in hCMEC/D3 human cerebral microvascular endothelial cells

  2015cited by this paper
• Validation of a tandem mass spectrometry method using combined extraction of 37 oxylipins and 14 endocannabinoid-related compounds including prostamides from biological matrices.

  2015cited by this paper
• Intestinal epithelial cells: regulators of barrier function and immune homeostasis

  2014cited by this paper
• Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3

  2014cited by this paper
• Interferon-γ-Induced Intestinal Epithelial Barrier Dysfunction by NF-κB/HIF-1α Pathway

  2014influential reference
• Intestinal permeability – a new target for disease prevention and therapy

  2014influential reference
• Altered Colonic Mucosal Polyunsaturated Fatty Acid (PUFA) Derived Lipid Mediators in Ulcerative Colitis: New Insight into Relationship with Disease Activity and Pathophysiology

  2013cited by this paper
• Modulation of intestinal barrier by intestinal microbiota: pathological and therapeutic implications.

  2013cited by this paper
• LC-MS/MS method for rapid and concomitant quantification of pro-inflammatory and pro-resolving polyunsaturated fatty acid metabolites.

  2013cited by this paper
• 5-Hydroxyeicosatetraenoic acid and leukotriene D4 increase intestinal epithelial paracellular permeability.

  2013cited by this paper
• Resveratrol Modulates Interleukin-1β-induced Phosphatidylinositol 3-Kinase and Nuclear Factor κB Signaling Pathways in Human Tenocytes

  2012cited by this paper
• Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids.

  2011cited by this paper
• Single and concerted effects of benzo[a]pyrene and flavonoids on the AhR and Nrf2-pathway in the human colon carcinoma cell line Caco-2.

  2011cited by this paper
• R Development Core Team (2010): R: A language and environment for statistical computing

  2010influential reference
• Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability*

  2010influential reference
• Vibrio cholerae Cytolysin Causes an Inflammatory Response in Human Intestinal Epithelial Cells That Is Modulated by the PrtV Protease

  2009cited by this paper
• Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

  2009cited by this paper
• Mechanism of Interferon-γ–Induced Increase in T84 Intestinal Epithelial Tight Junction

  2009influential reference
• Intestinal mucosal barrier function in health and disease

  2009cited by this paper
• Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases.

  2009cited by this paper
• Contribution of Intestinal Epithelial Cells to Innate Immunity of the Human Gut – Studies on Polarized Monolayers of Colon Carcinoma Cells

  2009cited by this paper
• Assessment of the bone quality of black male athletes using calcaneal ultrasound: a cross-sectional study

  2008cited by this paper
• Tumor necrosis factor-alpha potentiates genotoxic effects of benzo[a]pyrene in rat liver epithelial cells through upregulation of cytochrome P450 1B1 expression.

  2008cited by this paper
• Curcumin and resveratrol inhibit nuclear factor-kappaB-mediated cytokine expression in adipocytes

  2008cited by this paper
• Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

  2007cited by this paper
• Gene-Specific Effects of Inflammatory Cytokines on Cytochrome P450 2C, 2B6 and 3A4 mRNA Levels in Human Hepatocytes

  2007cited by this paper
• Evidence for an Aryl Hydrocarbon Receptor-Mediated Cytochrome P450 Autoregulatory Pathway

  2007cited by this paper
• Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development.

  2007influential reference
• Cytochrome P450 Profile of Colorectal Cancer: Identification of Markers of Prognosis

  2005cited by this paper
• Interferon‐γ induces internalization of epithelial tight junction proteins via a macropinocytosis‐like process

  2005cited by this paper
• MODULATION OF HUMAN CYTOCHROME P450 1B1 EXPRESSION BY 2,4,3′,5′-TETRAMETHOXYSTILBENE

  2005cited by this paper
• Abrogation of IFN-gamma mediated epithelial barrier disruption by serine protease inhibition.

  2005cited by this paper
• Interferon-γ selectively increases epithelial permeability to large molecules by activating different populations of paracellular pores

  2005cited by this paper
• Abrogation of IFN‐γ mediated epithelial barrier disruption by serine protease inhibition

  2005cited by this paper
• Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells

  2005cited by this paper
• Anti-inflammatory effects of resveratrol in lung epithelial cells: molecular mechanisms.

  2004cited by this paper
• The two NF-κB activation pathways and their role in innate and adaptive immunity

  2004influential reference
• Role of Aryl Hydrocarbon Receptor-mediated Induction of the CYP1 Enzymes in Environmental Toxicity and Cancer*

  2004influential reference
• The two NF-kappaB activation pathways and their role in innate and adaptive immunity.

  2004cited by this paper
• Interleukin-1beta, interleukin-6, tumour necrosis factor-alpha and interferon-gamma released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes.

  2003cited by this paper
• Cytochrome P450 1B1 (CYP1B1) is overexpressed in human colon adenocarcinomas relative to normal colon: implications for drug development.

  2003influential reference
• Over‐expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis

  2003cited by this paper
• Interleukin-1β, interleukin-6, tumour necrosis factor-α and interferon-γ released by a viral infection and an aseptic inflammation reduce CYP1A1, 1A2 and 3A6 expression in rabbit hepatocytes

  2003cited by this paper
• Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.

  2002cited by this paper
• Design, synthesis, and discovery of novel trans-stilbene analogues as potent and selective human cytochrome P450 1B1 inhibitors.

  2002influential reference
• Paradoxical coexpression of proinflammatory and down-regulatory cytokines in intestinal T cells in childhood celiac disease.

  2002cited by this paper
• Caco-2 monolayers in experimental and theoretical predictions of drug transport1PII of original article: S0169-409X(96)00415-2. The article was originally published in Advanced Drug Delivery Reviews 22 (1996) 67–84.1

  2001cited by this paper
• Regulation of cytochrome p450 by inflammatory mediators: why and how?

  2001cited by this paper
• Caco-2 monolayers in experimental and theoretical predictions of drug transport.

  2001cited by this paper
• Regulation, function, and tissue-specific expression of cytochrome P450 CYP1B1.

  2001influential reference
• Interferon-γ decreases barrier function in T84 cells by reducing ZO-1 levels and disrupting apical actin.

  1999cited by this paper
• Cellular localization of hepatic cytochrome 1B1 expression and its regulation by aromatic hydrocarbons and inflammatory cytokines.

  1999cited by this paper
• Selectivity of polycyclic inhibitors for human cytochrome P450s 1A1, 1A2, and 1B1.

  1998cited by this paper
• Differential Effects of Interleukin-1β, Interleukin-2, and Interferon-γ on the Inducible Expression of CYP 1A1 and CYP 1A2 in Cultured Rabbit Hepatocytes

  1997cited by this paper
• Differential effects of interleukin-1 beta, interleukin-2, and interferon-gamma on the inducible expression of CYP 1A1 and CYP 1A2 in cultured rabbit hepatocytes.

  1997cited by this paper
• Interferon γ down‐regulates cytochrome P450 3A genes in primary cultures of well‐differentiated rat hepatocytes

  1996cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995influential reference
• Effect of cytoplasmic pH on Ca2+‐stimulated eicosanoid biosynthesis in human platelets

  1994cited by this paper
• Agonistic and antagonistic effects of alpha-naphthoflavone on dioxin receptor function. Role of the basic region helix-loop-helix dioxin receptor partner factor Arnt.

  1994cited by this paper
• IFN-gamma modulation of epithelial barrier function. Time course, reversibility, and site of cytokine binding.

  1993cited by this paper
• Dual Stimulation of Phospholipase Activity in Human Monocytes Role of Protein Kinase C and Calcium in Arachidonic Acid Release and Eicosanoid Formation

  1988cited by this paper
• Dual stimulation of phospholipase activity in human monocytes. Role of calcium-dependent and calcium-independent pathways in arachidonic acid release and eicosanoid formation.

  1988cited by this paper

• Molecular crosstalk between AHR, CYP1B1, and ITGAM in diabetic nephropathy: Integrated insights from bioinformatics and experimental validation

  2026cites this paper
• Pharmacogenomic Pathways Underlying Variable Vedolizumab Response in Crohn’s Disease Patients: A Rare-Variant Analysis

  2026cites this paper
• CYP1B1 as a therapeutic target for S. aureus-induced mammary gland inflammation.

  2026cites this paper
• Targeting cytokine and chemokine signaling pathways for enhancing chemo-sensitivity in colorectal cancer

  2025cites this paper
• Utilization of AhR and GPR35 Receptor Ligands as Superfoods in Cancer Prevention for Individuals with IBD

  2025cites this paper
• Schisanhenol Alleviates Mycophenolic Acid-Induced Intestinal Epithelial Cell Barrier Damage by Activating the Nrf2/HO-1 Signaling Pathway

  2025cites this paper
• Effect of haloacetic acid water disinfection byproducts on intestinal barrier function in nematode Caenorhabditis elegans.

  2025cites this paper
• Deciphering the putative bioactive metabolites and the underlying mechanism of Juniperus horizontalis Moench (Creeping juniper) in the treatment of inflammation using network pharmacology and molecular docking.

  2023cites this paper
• Interferon-gamma (IFN-γ): Reviewing its mechanisms and signaling pathways on the regulation of endothelial barrier function.

  2023cites this paper
• Fecal microbiota transplantation improves chicken growth performance by balancing jejunal Th17/Treg cells

  2023cites this paper
• Chronic exposure to synthetic food colorant Allura Red AC promotes susceptibility to experimental colitis via intestinal serotonin in mice

  2022cites this paper
• Cannabinoids for Pain Management

  2021cites this paper
• Transcriptional Regulation of Drug Metabolizing CYP Enzymes by Proinflammatory Wnt5A Signaling in Human Coronary Artery Endothelial Cells

  2021cites this paper
• LncRNA H19 suppresses pyroptosis of cardiomyocytes to attenuate myocardial infarction in a PBX3/CYP1B1-dependent manner

  2021cites this paper
• Interferon γ treatment increases endocannabinoid and related N‐acylethanolamine levels in T84 human colon carcinoma cells

  2019cites this paper
• Involvement of CYP1B1 in interferon γ‐induced alterations of epithelial barrier integrity

  2018cites this paper