The fate of the primary cilium during myofibroblast transition

Myofibroblast transition from mesenchymal or epithelial precursors triggers loss of the primary cilium. In epithelial cells this requires contact injury and TGFβ and is mediated by Rac- and Smad3-dependent myosin phosphorylation. Thus the myofibroblast is a unique cilium-less cell with markedly reprogrammed ciliary signaling.

• Publication year

  2014

• Venue

  Molecular Biology of the Cell

• Publication date

  2014-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E13-07-0429PMID 24403605PMCID 3937090
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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