Expression of transmembrane carbonic anhydrases IX and XII in ovarian tumours

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Histopathology

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-2559.2006.02523.xPMID 17163844
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1998influential reference
• Expression of E‐cadherin, α‐catenin and β‐catenin in normal ovarian surface epithelium and epithelial ovarian cancers

  1998cited by this paper
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  1998influential reference
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  1995cited by this paper
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  1994cited by this paper
• Expression of MaTu‐MN protein in human tumor cultures and in clinical specimens

  1993cited by this paper
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  1992influential reference
• The pathogenesis of ovarian inclusion cysts and cystomas.

  1977cited by this paper
• The Pathogenesis of Ovarian Inclusion Cysts and Cystomas

  1977cited by this paper
• Cancer,Facts and Figures about.

  year unknowncited by this paper
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  year unknowncited by this paper

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