Total-body and myocardial substrate oxidation in congestive heart failure.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Metabolism: Clinical and Experimental

• Publication date

  1994-02-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0026-0495(94)90241-0PMID 8121298
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metabolic and cardiovascular benefits deriving from beta-adrenergic blockade in chronic congestive heart failure.

  1992cited by this paper
• Metabolic and cardiovascular benefits deriving from β-adrenergic blockade in chronic congestive heart failure

  1992cited by this paper
• Insulin resistance and hyperinsulinemia in patients with chronic congestive heart failure.

  1991cited by this paper
• Evidence for peripheral impaired glucose handling in patients with connective tissue diseases.

  1991cited by this paper
• Glucose and free fatty acid metabolism in non-insulin-dependent diabetes mellitus. Evidence for multiple sites of insulin resistance.

  1989cited by this paper
• Coronary hemodynamics and myocardial metabolism during and after pacing stress in normal humans.

  1989cited by this paper
• Banting lecture 1988. Role of insulin resistance in human disease.

  1988cited by this paper
• ROLE OF INSULIN-RESISTANCE IN HUMAN DISEASES

  1988cited by this paper
• Neurohormonal interactions and adaptations in congestive heart failure.

  1988cited by this paper
• The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

  1988cited by this paper
• Role of Insulin Resistance in Human Disease

  1988cited by this paper
• The theoretical bases of indirect calorimetry: a review.

  1988cited by this paper
• Hormonal effects of norepinephrine on acute glucose disposal in humans: a minimal model analysis.

  1988cited by this paper
• Estimation of Endogenous Glucose Production During Hyperinsulinemic-Euglycemic Glucose Clamps: Comparison of Unlabeled and Labeled Exogenous Glucose Infusates

  1987cited by this paper
• Heterogeneous myocardial catecholamine concentrations in patients with congestive heart failure.

  1987cited by this paper
• Primary role of glucagon release in the effect of beta-endorphin on glucose homeostasis in normal man.

  1987cited by this paper
• Acute elevation of free fatty acid levels leads to hepatic insulin resistance in obese subjects.

  1987cited by this paper
• Non-steady state: error analysis of Steele's model and developments for glucose kinetics.

  1987cited by this paper
• Symptoms and tests of ventricular performance in the evaluation of chronic heart failure.

  1986cited by this paper
• The adrenergic nervous system in heart failure.

  1984cited by this paper
• Correlation between muscle glycogen synthase activity and in vivo insulin action in man.

  1984cited by this paper
• Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure.

  1984cited by this paper
• Stimulation of gluconeogenesis by palmitic acid in rat hepatocytes: evidence that this effect can be dissociated from the provision of reducing equivalents.

  1983cited by this paper
• Effect of fatty acids on glucose production and utilization in man.

  1983cited by this paper
• Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relation to hemodynamic abnormalities in congestive heart failure.

  1982cited by this paper
• Glucose clamp technique: a method for quantifying insulin secretion and resistance.

  1979cited by this paper
• Plasma norepinephrine in congestive heart failure.

  1978cited by this paper
• Mechanism of palmityl coenzyme A inhibition of liver glycogen synthase.

  1977cited by this paper
• Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range.

  1976cited by this paper
• Control of phosphofructokinase from rat skeletal muscle. Effects of fructose diphosphate, AMP, ATP, and citrate.

  1976cited by this paper
• Relationship in man between plasma free fatty acids and myocardial metabolism of carbohydrate substrates.

  1971cited by this paper
• Role of free fatty acids in glucose homeostasis.

  1969cited by this paper
• The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.

  1963cited by this paper
• INFLUENCES OF GLUCOSE LOADING AND OF INJECTED INSULIN ON HEPATIC GLUCOSE OUTPUT *

  1959cited by this paper
• The effect of adrenaline and noradrenaline on hepatic blood flow and splanchnic carbohydrate metabolism in man

  1951cited by this paper

• Sirtuin 4 accelerates heart failure development by enhancing reactive oxygen species-mediated profibrotic transcriptional signaling

  2025cites this paper
• Illuminating Cardiac Remodeling: Insights From [ 18F]‐Fluorodeoxyglucose Positron Emission Tomography Imaging in Plakoglobin‐Associated Arrhythmogenic Cardiomyopathy

  2025cites this paper
• The Role of Insulin Resistance in Cardiorenal Metabolic Syndrome.

  2025cites this paper
• Imaging of metabolic dysfunction in genetic cardiomyopathies

  2025cites this paper
• Free fatty acids: independent predictors of long-term adverse cardiovascular outcomes in heart failure patients

  2024cites this paper
• Mitochondrial Dysfunction in Heart Failure: From Pathophysiological Mechanisms to Therapeutic Opportunities

  2024cites this paper
• Human cardiac metabolism.

  2024cites this paper
• Evaluation of Clinical Variables Affecting Myocardial Glucose Uptake in Cardiac FDG PET

  2024cites this paper
• Advances in myocardial energy metabolism: metabolic remodelling in heart failure and beyond

  2024cites this paper
• Myocardial Metabolism in Heart Failure with Preserved Ejection Fraction

  2024cites this paper
• Cardiac Metabolism, Reprogramming, and Diseases

  2023cites this paper
• Insulin resistance and metabolic flexibility as drivers of liver and cardiac disease in T2DM.

  2023cites this paper
• Novelties in the pharmacological approaches for chronic heart failure: new drugs and cardiovascular targets

  2023cites this paper
• Heart Failure and Drug Therapies: A Metabolic Review

  2022cites this paper
• Targeting Myocardial Substrate Metabolism in the Failing Heart: Ready for Prime Time?

  2022cites this paper
• CrossTalk proposal: Ketone bodies are an important metabolic fuel for the heart

  2021cites this paper
• Mitochondrial Bioenergetics and Dynamism in the Failing Heart

  2021cites this paper
• Heart Metabolism in Sepsis-Induced Cardiomyopathy—Unusual Metabolic Dysfunction of the Heart

  2021cites this paper
• Identifying functional metabolic shifts in heart failure with the integration of omics data and a heart-specific, genome-scale model.

  2021cites this paper
• Lactate and Myocardiac Energy Metabolism

  2021cites this paper
• KETONE METABOLISM IN THE FAILING HEART.

  2020cites this paper
• Metabolomic Profiling of Left Ventricular Diastolic Dysfunction in Women With or at Risk for HIV Infection: The Women's Interagency HIV Study

  2020cites this paper
• Metabolic effects of carvedilol through β‐arrestin proteins: investigations in a streptozotocin‐induced diabetes rat model and in C2C12 myoblasts

  2020cites this paper
• Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure

  2020cites this paper
• Role of Mitochondrial Quality Surveillance in Myocardial Infarction: From Bench to Bedside.

  2020cites this paper
• CaMKII and GLUT1 in heart failure and the role of gliflozins.

  2020cites this paper
• Myocardial Ketones Metabolism in Heart Failure: Karwi et al. Role of ketone in heart failure.

  2020cites this paper
• Glucose Metabolism in Cardiac Hypertrophy and Heart Failure

  2019cites this paper
• Cardiac Resynchronisation Therapy and Cellular Bioenergetics: Effects Beyond Chamber Mechanics

  2019cites this paper
• Adaptations in Protein Expression and Regulated Activity of Pyruvate Dehydrogenase Multienzyme Complex in Human Systolic Heart Failure

  2019cites this paper
• Cardiac manifestations of inherited metabolic disease linked to cellular metabolism of vitamin B12 : study in two murine models of invalidation of Mtr and MMACHC genes

  2019cites this paper
• Increased ketone body oxidation provides additional energy for the failing heart without improving cardiac efficiency.

  2019cites this paper
• Novel Concepts in Cardiac Energy Metabolism: From Biology to Disease

  2019cites this paper
• What fuels the failing heart ?

  2019cites this paper
• Cardiac metabolic imaging: current imaging modalities and future perspectives.

  2018cites this paper
• Metabolic Coordination of Physiological and Pathological Cardiac Remodeling

  2018cites this paper
• Clinical benefits of trimetazidine in heart failure

  2018cites this paper
• Increased Cardiac Uptake of Ketone Bodies and Free Fatty Acids in Human Heart Failure and Hypertrophic Left Ventricular Remodeling

  2018cites this paper
• Loss of Metabolic Flexibility in the Failing Heart

  2018cites this paper
• Mitochondrial membrane transporters and metabolic switch in heart failure

  2018cites this paper
• Hungry Hearts.

  2018cites this paper
• Metabolic Features of Heart Failure with Different Etiology

  2017cites this paper
• Lawrence Berkeley National Laboratory Recent Work Title Longitudinal Evaluation of Myocardial Fatty Acid and Glucose Metabolism in Fasted and Nonfasted Spontaneously Hypertensive Rats Using MicroPET / CT Permalink

  2017cites this paper
• Proteomics of acute heart failure in a rat post-myocardial infarction model

  2017cites this paper
• Pediatric and adult dilated cardiomyopathy represent distinct pathological entities.

  2017cites this paper
• Identification and Characterization of a Cardiomyopathy Syndrome Resulting from Loss of the Melanocortin 4 Receptor

  2017cites this paper
• Cardiac metabolism — A promising therapeutic target for heart failure

  2017cites this paper
• Consequences of Altered Short-Chain Carbon Metabolism in Heart Failure

  2017cites this paper
• Mitochondrial protein hyperacetylation in the failing heart.

  2016cites this paper
• Mitochondrial remodeling: Rearranging, recycling, and reprogramming.

  2016cites this paper
• Myocardial Disease Altered Myocardial Fatty Acid and Glucose Metabolism in Idiopathic Dilated Cardiomyopathy

  2016cites this paper
• Normalization of cardiac substrate utilization and left ventricular hypertrophy precede functional recovery in heart failure regression.

  2016cites this paper
• Exhaled Acetone Concentration Is Related to Hemodynamic Severity in Patients With Non-Ischemic Chronic Heart Failure.

  2016cites this paper
• The Failing Heart Relies on Ketone Bodies as a Fuel

  2016cites this paper
• Effects of the Novel Long-Acting GLP-1 Agonist, Albiglutide, on Cardiac Function, Cardiac Metabolism, and Exercise Capacity in Patients With Chronic Heart Failure and Reduced Ejection Fraction.

  2016influential citation
• Resveratrol Treatment of Mice With Pressure-Overload–Induced Heart Failure Improves Diastolic Function and Cardiac Energy Metabolism

  2015cites this paper
• Incretin-Related Drug Therapy in Heart Failure

  2015cites this paper
• Altered contractile mechanics and Ca2+ handling contribute to cardiomyopathy pathogenesis

  2015cites this paper
• Metabolic efficiency in remodeled failing hearts

  2015cites this paper
• Diastolic Dysfunction and Left Ventricle Remodeling in Men with Impaired Fasting Glucose

  2015cites this paper
• Gene Profiling, Energy Metabolism, and Remodeling of the Failing Heart

  2014cites this paper
• Heart Failure and Loss of Metabolic Control

  2014cites this paper
• Substrate Metabolism in the Diabetic Heart

  2014cites this paper
• Insights into metabolic remodeling of the hypertrophic and failing myocardium.

  2014cites this paper
• New-Onset Diabetes in Heart Failure Patients: A Complex Relationship with Clinical Implications

  2014cites this paper
• Metabolomic Analysis of Pressure-Overloaded and Infarcted Mouse Hearts

  2014cites this paper
• Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes

  2014cites this paper
• Hyperpolarized Metabolic MR in the Study of Cardiac Function and Disease.

  2014cites this paper
• Cardiac metabolism in hypertrophy and heart failure: implications for therapy

  2013cites this paper
• Using metabolomics to assess myocardial metabolism and energetics in heart failure.

  2013cites this paper
• A systems biology approach to model cardiomyocyte metabolism

  2013cites this paper
• Longitudinal Evaluation of Left Ventricular Substrate Metabolism, Perfusion, and Dysfunction in the Spontaneously Hypertensive Rat Model of Hypertrophy Using Small-Animal PET/CT Imaging

  2013cites this paper
• Metabolic remodeling in chronic heart failure

  2013cites this paper
• Adrenergic activation, fuel substrate availability, and insulin resistance in patients with congestive heart failure.

  2013cites this paper
• Longitudinal Evaluation of Myocardial Fatty Acid and Glucose Metabolism in Fasted and Nonfasted Spontaneously Hypertensive Rats Using MicroPET/CT

  2013cites this paper
• Persistent Overexpression of Phosphoglycerate Mutase, a Glycolytic Enzyme, Modifies Energy Metabolism and Reduces Stress Resistance of Heart in Mice

  2013cites this paper
• Frequency-selective Methods for Hyperpolarized 13C Cardiac Magnetic Resonance Imaging

  2012cites this paper
• The Endothelium, Cardiovascular Disease, and Therapy

  2012cites this paper
• Roles of transcriptional corepressor RIP140 and coactivator PGC-1α in energy state of chronically infarcted rat hearts and mitochondrial function of cardiomyocytes.

  2012cites this paper
• Reversible heart failure: toxins, tachycardiomyopathy and mitochondrial abnormalities

  2012cites this paper
• Variable Cardiac 18FDG Patterns Seen in Oncologic Positron Emission Tomography Computed Tomography: Importance for Differentiating Normal Physiology From Cardiac and Paracardiac Disease

  2012cites this paper
• [Heart failure and development of type 2 diabetes mellitus].

  2012cites this paper
• Metabolic therapy for heart failure including diastolic heart failure

  2012cites this paper
• Hyperpolarized 13C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart

  2012cites this paper
• Availability of energetic substrates and exercise performance in heart failure with or without diabetes

  2012cites this paper
• Myocardial substrate metabolism in heart disease.

  2012influential citation
• Seven-year mortality in heart failure patients with undiagnosed diabetes: an observational study

  2011cites this paper
• Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.

  2011cites this paper
• Molecular Changes in Fatty Acid Oxidation in the Failing Heart

  2011cites this paper
• Mitochondrial protein phosphorylation as a regulatory modality: implications for mitochondrial dysfunction in heart failure.

  2011cites this paper
• A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects 1 – 3

  2011cites this paper
• Concept paper: antihyperglycemic therapy and the diabetic heart--do we really know enough?

  2011cites this paper
• How to differentiate benign versus malignant cardiac and paracardiac 18F FDG uptake at oncologic PET/CT.

  2011cites this paper
• Optimization of Cardiac Metabolism in Heart Failure

  2011cites this paper
• Metabolic remodelling in human heart failure.

  2011cites this paper
• Risk factors and metabolic mechanisms in the pathogenesis of uraemic cardiac disease.

  2011influential citation
• Modulating fatty acid oxidation in heart failure.

  2011cites this paper
• A high-fat diet impairs cardiac high-energy phosphate metabolism and cognitive function in healthy human subjects.

  2011cites this paper
• Myocardial fatty acid metabolism in health and disease.

  2010cites this paper
• Assessment of Metabolic Phenotypes in Patients with Non-ischemic Dilated Cardiomyopathy Undergoing Cardiac Resynchronization Therapy

  2010cites this paper