Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Nucleic Acids Res.

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1093/NAR/GKG050PMID 12519968PMCID PMC165497
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Database resources of the National Center for Biotechnology Information: update

  2004influential reference
• Database resources of the National Center for Biotechnology Information: 2002 update

  2002cited by this paper
• BLAT--the BLAST-like alignment tool.

  2002cited by this paper
• GeneCardsTM 2002: towards a complete, object-oriented, human gene compendium

  2002cited by this paper
• euGenes: a eukaryote genome information system

  2002cited by this paper
• Genew: the Human Gene Nomenclature Database

  2002cited by this paper
• The Ensembl genome database project

  2002cited by this paper
• The complete human olfactory subgenome.

  2001cited by this paper
• GeneLynx: a gene-centric portal to the human genome.

  2001cited by this paper
• Extending traditional query-based integration approaches for functional characterization of post-genomic data

  2001cited by this paper
• Introducing RefSeq and LocusLink: curated human genome resources at the NCBI.

  2000cited by this paper
• GESTALT: a workbench for automatic integration and visualization of large-scale genomic sequence analyses

  2000cited by this paper
• The DNA sequence of human chromosome 21

  2000cited by this paper
• The olfactory receptor gene superfamily: data mining, classification, and nomenclature

  2000cited by this paper
• GeneCards: a novel functional genomics compendium with automated data mining and query reformulation support

  1998cited by this paper
• Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome.

  1998cited by this paper
• Comparison of DNA sequences with protein sequences.

  1997cited by this paper
• Sequence mapping by electronic PCR

  1997cited by this paper
• GeneCards: integrating information about genes, proteins and diseases.

  1997cited by this paper
• Using CLUSTAL for multiple sequence alignments.

  1996cited by this paper
• Architecture and anatomy of the chromosomal locus in human chromosome 21 encoding the Cu/Zn superoxide dismutase.

  1985cited by this paper
• Human cytoplasmic superoxide dismutase cDNA clone: a probe for studying the molecular biology of Down syndrome.

  1982cited by this paper

• Systematic Exploration of Potential Toxicity Targets and Molecular Mechanisms of Emerging Short‐Chain PFAS Substitutes: PFBA‐ and PFBS‐Induced Hepatocellular Carcinoma Based on Toxicity Network Analysis, Machine Learning, and Biomimetic Calculations

  2025cites this paper
• Network Pharmacology, Molecular Docking, Molecular Dynamics to Explore the Mechanism of Danggui Shaoyao Powder for Hepatic Encephalopathy.

  2025cites this paper
• Piplartine alleviates sepsis-induced acute kidney injury by inhibiting TSPO-mediated macrophage pyroptosis.

  2025cites this paper
• Identification of Therapeutic Targets for Osteoporosis through Multiomics Integration and the Potential Dual Role of Androgen Receptor Signaling in Its Pathophysiology

  2025cites this paper
• Identification and validation of PARK7 as a novel mitochondria-related signature associated with immune microenvironment in asthma.

  2025cites this paper
• Jiedu Tongluo Tiaogan Formula Modulates Glycolipid Metabolism in Type 2 Diabetes via Pyroptosis: Network Pharmacology and In Vivo Analysis.

  2025cites this paper
• On the mechanism of wogonin against acute monocytic leukemia using network pharmacology and experimental validation

  2024cites this paper
• In Silico Insights Reveal Fibronectin 1 as a Theranostic Marker in Gastric Cancer

  2024cites this paper
• Network Pharmacology, Molecular Docking, and Experimental Validation to Investigate the Mechanism of Qifu Longkui Decoction in the Treatment of Colorectal Cancer

  2024cites this paper
• Hesperetin Inhibits Bladder Cancer Cell Proliferation and Promotes Apoptosis and Cycle Arrest by PI3K/AKT/FoxO3a and ER Stress-mitochondria Pathways.

  2024cites this paper
• Network Pharmacology Approach and Partial Experimental Validation of Aidi Injection Solution for the Treatment of Colorectal Cancer

  2024cites this paper
• Sanguinarine identified as a natural dual inhibitor of AURKA and CDK2 through network pharmacology and bioinformatics approaches

  2024cites this paper
• Mechanisms of He Shi Yu Lin formula in treating premature ovarian insufficiency: insights from network pharmacology and animal experiments

  2024cites this paper
• Astragalus Polysaccharide Mitigates Rhabdomyolysis-Induced Acute Kidney Injury via Inhibition of M1 Macrophage Polarization and the cGAS-STING Pathway

  2024cites this paper
• Elucidating the Molecular Mechanisms of Pterostilbene Against Cervical Cancer Through an Integrated Bioinformatics and Network Pharmacology Approach.

  2024cites this paper
• Decoding Molecular Mechanism Underlying Human Olfactory Receptor OR8D1 Activation by Sotolone Enantiomers.

  2024cites this paper
• Network pharmacology and in vitro experiments reveal sophoridine‐induced apoptosis and G1 phase arrest via ROS‐dependent PI3K/Akt/FoxO3a pathway activation in human bladder cancer cells

  2024influential citation
• Visual analysis on ferroptosis and its cross-talk to coronavirus disease 2019 (COVID-19)

  2024cites this paper
• Network pharmacology analysis and clinical verification of Panax notoginseng saponins in deep venous thrombosis prevention

  2024cites this paper
• Exploring the potential mechanism of action of ursolic acid against gastric cancer and COVID-19 using network pharmacology and bioinformatics analysis.

  2023cites this paper
• Chemical constituents and hepatoprotective properties of Rhododendron simsii Planch extract in Con A-induced autoimmune hepatitis

  2023cites this paper
• Exploring underlying mechanism of artesunate in treatment of acute myeloid leukemia using network pharmacology and molecular docking

  2023cites this paper
• Exploring the mechanism of ellagic acid against gastric cancer based on bioinformatics analysis and network pharmacology

  2023cites this paper
• Exploring the Potential Molecular Mechanism of the Shugan Jieyu Capsule in the Treatment of Depression through Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation.

  2023cites this paper
• sGC agonist BAY1021189 promotes thoracic aortic dissection formation by accelerating vascular smooth muscle cell phenotype switch.

  2023cites this paper
• Exploring the mechanism of Shexiang Tongxin dropping pill in the treatment of microvascular angina through network pharmacology and molecular docking

  2022cites this paper
• Study on molecular biological mechanism of Chinese herbal medicines for the treatment of gastric precancerous lesions based on data mining and network pharmacology.

  2022cites this paper
• Gou Qi Zi inhibits proliferation and induces apoptosis through the PI3K/AKT1 signaling pathway in non-small cell lung cancer

  2022cites this paper
• Genetic Factors and Their Role in the Pathogenesis of Biliary Atresia

  2022cites this paper
• Qiangguyin inhibited fat accumulation in OVX mice through the p38 MAPK signaling pathway to achieve anti-osteoporosis effects.

  2022cites this paper
• Exploring the Potential Mechanism of Danshen in the Treatment of Concurrent Ischemic Heart Disease and Depression Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation

  2022cites this paper
• In vitro anti-cancer effect of marmesin by suppression of PI3K/Akt pathway in esophagus cancer cells

  2021cites this paper
• An Evolutionary Based Strategy for Predicting Rational Mutations in G Protein-Coupled Receptors

  2021cites this paper
• Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1

  2021cites this paper
• Exploring the Pharmacological Mechanism of Radix Salvia Miltiorrhizae in the Treatment of Radiation Pneumonia by Using Network Pharmacology

  2021cites this paper
• Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis

  2021cites this paper
• Whole-Genome Sequencing Reveals Exonic Variation of ASIC5 Gene Results in Recurrent Pregnancy Loss

  2021cites this paper
• Network pharmacology study on the mechanism of Qiangzhifang in the treatment of panic disorder

  2021cites this paper
• Network pharmacology study on the mechanism of the herb pair of prepared Rehmannia root-Chinese arborvitae kernel for anxiety disorders.

  2021cites this paper
• Expert Curation of the Human and Mouse Olfactory Receptor Gene Repertoires Identi�es Conserved Coding Regions Split Across Two Exons

  2021cites this paper
• The Mechanism of Lavender Essential Oil in the Treatment of Acute Colitis Based on “Quantity–Effect” Weight Coefficient Network Pharmacology

  2021cites this paper
• Study on the Potential Mechanism of Fructus Tribuli in the Treatment of Hypertensive Vascular Remodeling Based on Network Pharmacology and Molecular Docking

  2021cites this paper
• Potential mechanism of Ziyin Tongluo Formula in the treatment of postmenopausal osteoporosis: based on network pharmacology and ovariectomized rat model

  2021cites this paper
• Utilizing Network Pharmacology to Explore the Possible Mechanism of Coptidis Rhizoma in Kawasaki Disease

  2020cites this paper
• Exploration of the mechanism of Ziyin Tongluo Formula on preventing and treating postmenopausal osteoporosis based on the network pharmacology and molecular docking

  2020cites this paper
• Utilizing network pharmacology to explore the underlying mechanism of Qiangzhi decoction in treating Tourette's syndrome.

  2020cites this paper
• Uncovering the Mechanisms of Leech and Centipede Granules in the Treatment of Diabetes Mellitus-induced Erectile Dysfunction utilising Network Pharmacology.

  2020cites this paper
• Genetic Architecture of Gene Expression in European and African Americans: An eQTL Mapping Study in GENOA.

  2020cites this paper
• A comprehensive investigation of the mRNA and protein level of ACE2, the putative receptor of SARS-CoV-2, in human tissues and blood cells

  2020influential citation
• Manipulation of JAK/STAT Signalling by High-Risk HPVs: Potential Therapeutic Targets for HPV-Associated Malignancies

  2020influential citation
• Network Pharmacology Approach to Explore the Potential Mechanisms of Jieduan-Niwan Formula Treating Acute-on-Chronic Liver Failure

  2020cites this paper
• Network Pharmacology to Uncover the Molecular Mechanisms of Action of LeiGongTeng for the Treatment of Nasopharyngeal Carcinoma

  2020cites this paper
• Expert curation of the human and mouse olfactory receptor gene repertoires identifies conserved coding regions split across two exons

  2019cites this paper
• Protective effects of a combination of ShengMai-Yin and Ganmaidazao decoction in a mouse model of type 2 diabetes with nonalcoholic fatty liver disease.

  2019cites this paper
• Sense of Smell: Structural, Functional, Mechanistic Advancements and Challenges in Human Olfactory Research

  2019cites this paper
• Copper-mediated thiol potentiation and mutagenesis-guided modeling suggest a highly conserved copper-binding motif in human OR2M3

  2019cites this paper
• Study of the mechanism underlying therapeutic effect of Compound Longmaining on myocardial infarction using a network pharmacology-based approach.

  2019cites this paper
• A unified nomenclature for vertebrate olfactory receptors

  2019cites this paper
• A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae

  2019cites this paper
• Brain Region-Specific Gene Signatures Revealed by Distinct Astrocyte Subpopulations Unveil Links to Glioma and Neurodegenerative Diseases

  2019influential citation
• Network Pharmacology Identifies the Mechanisms of Action of Shaoyao Gancao Decoction in the Treatment of Osteoarthritis

  2019cites this paper
• Chapter 2 HORDE : Comprehensive Resource for Olfactory Receptor Genomics

  2018cites this paper
• Human Olfactory Receptors: Novel Cellular Functions Outside of the Nose.

  2018cites this paper
• EF Hand Domain Family Member D2 Is Required for T Cell Cytotoxicity

  2018cites this paper
• Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation

  2018cites this paper
• Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes

  2018cites this paper
• Database Creation and Utility

  2018cites this paper
• GeneSeeker :

  2017influential citation
• TrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids

  2017cites this paper
• Global gene expression profiling of healthy human brain and its application in studying neurological disorders

  2017cites this paper
• Transcriptomic Analysis of the Claudin Interactome in Malignant Pleural Mesothelioma: Evaluation of the Effect of Disease Phenotype, Asbestos Exposure, and CDKN2A Deletion Status

  2017cites this paper
• Meta-analysis of massive parallel reporter assays enables functional regulatory elements prediction

  2017influential citation
• DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

  2017cites this paper
• Network Diffusion-Based Prioritization of Autism Risk Genes Identifies Significantly Connected Gene Modules

  2017cites this paper
• Structural determinants of a conserved enantiomer-selective carvone binding pocket in the human odorant receptor OR1A1

  2017cites this paper
• PharmacoDB: an integrative database for mining in vitro anticancer drug screening studies

  2017cites this paper
• PhyloPro2.0: a database for the dynamic exploration of phylogenetically conserved proteins and their domain architectures across the Eukarya

  2016cites this paper
• Genic insights from integrated human proteomics in GeneCards

  2016cites this paper
• The genomes of two bat species with long constant frequency echolocation calls

  2016cites this paper
• On-line human action recognition based on P-LDCNF

  2016cites this paper
• Thyroid malignant neoplasm-associated biomarkers as targets for oncolytic virotherapy

  2016cites this paper
• Bioinformatics and Computational Biology: 21st Brazilian Conference, X-Meeting 2025, João Pessoa, Brazil, June 3–6, 2025, Proceedings

  2015cites this paper
• Biological Databases for Human Research

  2015cites this paper
• Loss of function of PGAP1 as a cause of severe encephalopathy identified by Whole Exome Sequencing: Lessons of the bioinformatics pipeline.

  2015cites this paper
• NFI‐C2 temporal‐spatial expression and cellular localization pattern during tooth formation

  2015cites this paper
• PPIA rs6850: A > G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease

  2015cites this paper
• Human Olfactory Receptors Expression and Their Role in Non-Olfactory Tissues A Mini-Review

  2015cites this paper
• Unravelling the Olfactory Sense: From the Gene to Odor Perception.

  2015cites this paper
• Association of Network Centralities to Uncover the Novel Protein Interactions in Rheumatoid Arthritis

  2015cites this paper
• Identification and functional analysis of the BIM interactome; new clues on its possible involvement in Epstein–Barr Virus-associated diseases

  2015cites this paper
• A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics

  2014cites this paper
• The Structure, Function and Evolution of the Extracellular Matrix: A Systems-Level Analysis

  2014cites this paper
• Web scraping technologies in an API world

  2014cites this paper
• GPCR & company: databases and servers for GPCRs and interacting partners.

  2014cites this paper
• Environmental and Genetic Contributors to Salivary Testosterone Levels in Infants

  2014cites this paper
• Genome-wide Expression Profiles of Necrotizing Enterocolitis Versus Spontaneous Intestinal Perforation in Human Intestinal Tissues: Dysregulation of Functional Pathways

  2014cites this paper
• Trevigen’s γ-H2AX Pharmacodynamic Assay

  2014cites this paper
• CTDSPL (CTD (Carboxy-Terminal Domain, RNA Polymerase II, Polypeptide A) Small Phosphatase-Like)

  2014cites this paper
• VEGF mRNA and Protein Concentrations in the Developing Human Eye

  2014cites this paper
• Damage γ-H 2 AX Pharmacodynamic Assay

  2014cites this paper