Climbing nitrogenase: toward a mechanism of enzymatic nitrogen fixation.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Accounts of Chemical Research

• Publication date

  2009-05-19

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1021/ar8002128PMID 19267458PMCID PMC2684573
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanism of Mo-dependent nitrogenase.

  2009cited by this paper
• Electronic structure and reactivity of three-coordinate iron complexes.

  2008cited by this paper
• ENDOR characterization of a synthetic diiron hydrazido complex as a model for nitrogenase intermediates.

  2008cited by this paper
• Diazene (HN=NH) is a substrate for nitrogenase: insights into the pathway of N2 reduction.

  2007cited by this paper
• Inaugural Article: Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state

  2007cited by this paper
• Testing if the interstitial atom, X, of the nitrogenase molybdenum-iron cofactor is N or C: ENDOR, ESEEM, and DFT studies of the S = 3/2 resting state in multiple environments.

  2007cited by this paper
• Breaking the N2 triple bond: insights into the nitrogenase mechanism.

  2006cited by this paper
• How many metals does it take to fix N2? A mechanistic overview of biological nitrogen fixation

  2006cited by this paper
• Mid- to high-valent imido and nitrido complexes of iron.

  2006cited by this paper
• A methyldiazene (HNNCH3)-derived species bound to the nitrogenase active-site FeMo cofactor: Implications for mechanism

  2006cited by this paper
• Diversity of Nitrogenase Systems in Diazotrophs

  2006cited by this paper
• Reduction of dinitrogen

  2006cited by this paper
• Substrate interactions with the nitrogenase active site.

  2005cited by this paper
• Catalytic reduction of dinitrogen to ammonia at a single molybdenum center

  2005cited by this paper
• Trapping a hydrazine reduction intermediate on the nitrogenase active site.

  2005cited by this paper
• Trapping H- bound to the nitrogenase FeMo-cofactor active site during H2 evolution: characterization by ENDOR spectroscopy.

  2005cited by this paper
• Intermediates Trapped during Nitrogenase Reduction of N⋮N, CH3−NNH, and H2N−NH2

  2005cited by this paper
• Intermediates trapped during nitrogenase reduction of N triple bond N, CH3-N=NH, and H2N-NH2.

  2005cited by this paper
• Structural basis of biological nitrogen fixation

  2005cited by this paper
• Electron inventory, kinetic assignment (E(n)), structure, and bonding of nitrogenase turnover intermediates with C2H2 and CO.

  2005cited by this paper
• An organometallic intermediate during alkyne reduction by nitrogenase.

  2004cited by this paper
• Chemical activity of the nitrogenase FeMo cofactor with a central nitrogen ligand: density functional study.

  2004cited by this paper
• Kinetic isotope effects on the rate-limiting step of heme oxygenase catalysis indicate concerted proton transfer/heme hydroxylation.

  2003cited by this paper
• Catalytic Reduction of Dinitrogen to Ammonia at a Single Molybdenum Center

  2003cited by this paper
• Nitrogenase MoFe-Protein at 1.16 Å Resolution: A Central Ligand in the FeMo-Cofactor

  2002cited by this paper
• Molecular mechanisms of photosynthesis

  2002cited by this paper
• Principles of pulse electron paramagnetic resonance

  2001cited by this paper
• Duplication and extension of the Thorneley and Lowe kinetic model for Klebsiella pneumoniae nitrogenase catalysis using a MATHEMATICA software platform.

  2001cited by this paper
• Mechanistic features and structure of the nitrogenase alpha-Gln195 MoFe protein.

  2001cited by this paper
• Differential effects on N(2) binding and reduction, HD formation, and azide reduction with alpha-195(His)- and alpha-191(Gln)-substituted MoFe proteins of Azotobacter vinelandii nitrogenase.

  2000cited by this paper
• Differential Effects on N2 Binding and Reduction, HD Formation, and Azide Reduction with α-195His- and α-191Gln-Substituted MoFe Proteins of Azotobacter vinelandii Nitrogenase†

  2000cited by this paper
• Spectroscopic evidence for changes in the redox state of the nitrogenase P-cluster during turnover.

  1999cited by this paper
• Investigation of CO binding and release from Mo-nitrogenase during catalytic turnover.

  1998cited by this paper
• CO Binding to the FeMo Cofactor of CO-Inhibited Nitrogenase: 13CO and 1H Q-Band ENDOR Investigation

  1997cited by this paper
• The Chatt cycle and the mechanism of enzymic reduction of molecular nitrogen

  1996cited by this paper
• IDENTIFICATION OF THE CO-BINDING CLUSTER IN NITROGENASE MOFE PROTEIN BY ENDOR OF 57FE ISOTOPOMERS

  1996cited by this paper
• Structure−Function Relationships of Alternative Nitrogenases

  1996cited by this paper
• Structureminus signFunction Relationships of Alternative Nitrogenases.

  1996cited by this paper
• Mechanism of Molybdenum Nitrogenase.

  1996cited by this paper
• Metalloenzyme Active-Site Structure and Function through Multifrequency CW and Pulsed ENDOR

  1993cited by this paper
• Effects of homocitrate, homocitrate lactone, and fluorohomocitrate on nitrogenase in NifV- mutants of Azotobacter vinelandii

  1991cited by this paper
• Klebsiella pneumoniae nitrogenase. Mechanism of acetylene reduction and its inhibition by carbon monoxide.

  1990cited by this paper
• Nitrogenase of Klebsiella pneumoniae. Hydrazine is a product of azide reduction.

  1981cited by this paper
• Hydrazine as a substrate and inhibitor of Azotobacter vinelandii nitrogenase.

  1980cited by this paper
• Iron-sulfur clusters in the molybdenum-iron protein component of nitrogenase. Electron paramagnetic resonance of the carbon monoxide inhibited state.

  1979cited by this paper

• Quantum Mechanical/Molecular Mechanical (QM/MM) Studies of Enzymes.

  2026cites this paper
• Synthesis and characterization of single crystal XRD of polymeric sodium ferric EDTA mono hydrate complex by solvent evaporation approach

  2026cites this paper
• Design Refinement of Catalytic System for Scale-Up Mild Nitrogen Photo-Fixation

  2025cites this paper
• Enhancing photocatalytic nitrogen fixation through controlled acid corrosion of 1D TiO2 nanobelts

  2025cites this paper
• Effects of Microbial Fertilizer on Soil Physicochemical Properties and Fungal Community Diversity in Saline–Alkali Soil Cultivated with Oil Sunflowers

  2025cites this paper
• A bioinspired hetero-binuclear iron-molybdenum complex supported by tridentate sulfur donors and its catalytic activity toward hydrazine disproportionation.

  2025cites this paper
• Nickel Incorporation into Fresh Iron Sulfide Precipitates Modulates Selectivity in Nitrite, Carbon Dioxide, and Proton Reduction.

  2025cites this paper
• A ligand-centered review on structure, synthesis, and significance of diiron coordination complexes

  2025cites this paper
• Isolation of a Terminal Cobalt Nitride in a Metal-Organic Framework.

  2025cites this paper
• SELECTION OF NON-SYMBIOTIC PHOSPHATE-SOLUBILIZING IAZOTROPHIC BACTERIA

  2025cites this paper
• Minireview on Perovskite Oxide-Based Materials toward Enhanced Electrocatalytic Nitrate Reduction for Ammonia Synthesis: Advances and Perspectives

  2025cites this paper
• Genome-based analyses to learn from and about Paenibacillus sonchi genomovar Riograndensis SBR5T

  2024cites this paper
• Electrochemical dinitrogen to ammonia reduction at a nickel(ii) site: an easy access to an air-stable catalyst

  2024cites this paper
• EDA-NOCV analyses of M−E2 bond: E2 binding and activation [E2 = N2, H2]

  2024cites this paper
• Screening of metal–organic frameworks for efficient electrocatalytic nitrogen reduction

  2024cites this paper
• Chinese-Lantern shaped [MnII2MnIII6NaI3] cluster assembled from Schiff base and azide bridges: Synthesis, magnetic study and catecholase-like activity

  2024cites this paper
• Computational design of cooperatively acting molecular catalyst systems: carbene based tungsten- or molybdenum-catalysts with rhodium- or iridium-complexes for the ionic hydrogenation of N2 to NH3.

  2024cites this paper
• The synthesis and characterization of an iron(VII) nitrido complex

  2024cites this paper
• Rhizobium-Linked Nutritional and Phytochemical Changes Under Multitrophic Functional Contexts in Sustainable Food Systems

  2024cites this paper
• Cluster dynamics of heterometallic trinuclear clusters during ligand substitution, redox chemistry, and group transfer processes

  2024cites this paper
• Beyond the triple bond: unlocking dinitrogen activation with tailored superbase phosphines.

  2024cites this paper
• Progress in Biomass Electro‐Valorization for Paired Electrosynthesis of Valuable Chemicals and Fuels

  2024cites this paper
• Construction of electron rich Fe active sites by FeCu alloy anchoring on carbon nitride for photocatalytic nitrogen reduction

  2024cites this paper
• Recent developments in synthesis, properties, and applications of 2D Janus MoSSe and MoSexS(1-x) alloys

  2024cites this paper
• Enhancing Soil Health and Plant Growth through Microbial Fertilizers: Mechanisms, Benefits, and Sustainable Agricultural Practices

  2024cites this paper
• Valence-to-core X-ray emission spectroscopy of transition metal tetrahalides: mechanisms governing intensities.

  2024cites this paper
• Construction and Function of Thiolate-Bridged Diiron NxHy Nitrogenase Model Complexes.

  2024cites this paper
• The nitrogenase mechanism: new roles for the dangler?

  2024cites this paper
• On the Shoulders of Giants—Reaching for Nitrogenase

  2023cites this paper
• Enroute to the Carbon-Neutrality Goals via the Targeted Development of Ammonia as a Potential Nitrogen-Based Energy Carrier

  2023cites this paper
• Tuning Catalyst Selectivity for Ammonia vs Hydrogen: An Investigation into the Coprecipitation of Mo and Fe Sulfides.

  2023cites this paper
• Missing-Linker-Confined Single-Atomic Pt Nanozymes for Enzymatic Theranostics of Tumor.

  2023cites this paper
• Research Progress in Composite Materials for Photocatalytic Nitrogen Fixation

  2023cites this paper
• Work Function-Tailored Nitrogenase-like Fe Double-Atom Catalysts on Transition Metal Dichalcogenides for Nitrogen Fixation

  2023cites this paper
• A Broad Light-Harvesting Conjugated Oligoelectrolyte Enables Photocatalytic Nitrogen Fixation in a Bacterial Biohybrid.

  2023cites this paper
• Enzymatic Electrochemical/Fluorescent Nanobiosensor for Detection of Small Chemicals

  2023cites this paper
• Synthesis of Bis(silylene) Iron Chlorides and Their Catalytic Activity for Dinitrogen Silylation.

  2023cites this paper
• Bottlebrush polymeric catalyst: Boosting activity for CO2/epoxide copolymerization

  2023cites this paper
• Pincer Ligand Supported Fe Complex Catalysed Dinitrogen Reduction to NH 3 Using FLP‐H 2 as the Hydrogen Source: DFT Studies

  2023cites this paper
• Nitrogen fixation and transformation with main group elements.

  2022cites this paper
• Tale of Three Molecular Nitrides: Mononuclear Vanadium (V) and (IV) Nitrides As Well As a Mixed-Valence Trivanadium Nitride Having a V3N4 Double-Diamond Core.

  2022cites this paper
• Paramagnetic resonance investigation of mono- and di-manganese-containing systems in biochemistry.

  2022cites this paper
• 2022 roadmap on low temperature electrochemical CO2 reduction

  2022cites this paper
• Recent advances in transition metal sulfide-based electrocatalysts and photocatalysts for nitrogen fixation

  2022cites this paper
• Highly active bifunctional dual-arm organoboron catalysts bearing cooperative intramolecular structures for the copolymerization of CO2 and epoxides

  2022cites this paper
• Sporomusa ovata as Catalyst for Bioelectrochemical Carbon Dioxide Reduction: A Review Across Disciplines From Microbiology to Process Engineering

  2022cites this paper
• Dehydrated UiO-66(SH)2: The Zr-O Cluster and Its Photocatalytic Role Mimicking the Biological Nitrogen Fixation.

  2022cites this paper
• Bonding and stability of dinitrogen-bonded donor base-stabilized Si(0)/Ge(0) species [(cAACMe–Si/Ge)2(N2)]: EDA-NOCV analysis

  2022cites this paper
• Estimations of Fe0/−1–N2 interaction energies of iron(0)-dicarbene and its reduced analogue by EDA-NOCV analyses: crucial steps in dinitrogen activation under mild conditions

  2022cites this paper
• Enabling efficient electrocatalytic conversion of N2 to NH3 by Ti3C2 MXene loaded with semi-metallic 1 T'-MoS2 nanosheets

  2022cites this paper
• The Role of the Redox Non-Innocent Hydroxyl Ligand in the Activation of O2 Performed by [Ni(H)(OH)].

  2022cites this paper
• Dinitrogen Binding Relevant to FeMoco of Nitrogenase: Clear Visualization of σ‐Donation and π‐Backdonation from Deformation Electron Densities around Carbon/Silicon‐Iron Site

  2022cites this paper
• EDA‐NOCV analysis of carbene‐borylene bonded dinitrogen complexes for deeper bonding insight: A fair comparison with a metal‐dinitrogen system

  2022cites this paper
• Stability and bonding of carbon(0)‐iron−N2 complexes relevant to nitrogenase co‐factor: EDA‐NOCV analyses

  2022cites this paper
• Valence Engineering at the Interface of Mos2/Mo2c Heterostructure for Bionic Nitrogen Reduction

  2022cites this paper
• Terminal N2 Dissociation in [(PNN)Fe(N2)]2(μ‐N2) Leads to Local Spin‐State Changes and Augmented Bridging N2 Activation

  2022cites this paper
• Dinitrogen Binding and Activation: Bonding Analyses of Stable V(III/I)–N2–V(III/I) Complexes by the EDA–NOCV Method from the Perspective of Vanadium Nitrogenase

  2022cites this paper
• Regulating Electronic Structure in Bi2O3 Architectures by Ti mediation: A Strategy for Dual Active Sites Synergistically Promoting Photocatalytic Nitrogen Hydrogenation.

  2022cites this paper
• Mechanistic analysis of the dissociative reduction of nitrogen to ammonia by ZnMn2O4 catalyst derived from spent batteries

  2022cites this paper
• Synergy between metals for small molecule activation: Enzymes and bio-inspired complexes

  2021cites this paper
• Photocatalytic nitrogen-oxide conversion in red soil

  2021cites this paper
• Self‐Supporting Electrodes for Gas‐Involved Key Energy Reactions

  2021cites this paper
• Computational study of ammonia generation by iron( III ) and iron( IV ) complexes supported by trigonal bipyramidal iron

  2021cites this paper
• Enhanced Photofixation of Dinitrogen to Ammonia over a Biomimetic Metal (Fe,Mo)-Doped Mesoporous MCM-41 Zeolite Catalyst under Ambient Conditions

  2021cites this paper
• Estimations of Fe–N2 Intrinsic Interaction Energies of Iron–Sulfur/Nitrogen–Carbon Sites: A Deeper Bonding Insight by EDA-NOCV Analysis of a Model Complex of the Nitrogenase Cofactor

  2021cites this paper
• Bioanorganische Chemie

  2021cites this paper
• Plasmonic Catalysis for N 2 Fixation

  2021cites this paper
• N N bond cleavage upon reduction and protonation of phenylazophenylate coordinated to ruthenium complex

  2021cites this paper
• Advancement of Bismuth‐Based Materials for Electrocatalytic and Photo(electro)catalytic Ammonia Synthesis

  2021cites this paper
• Preliminary analysis of Endophytic Plant Growth Promoting (PGP) Methylobacterium sp. Isolated from Palm Oil (Elaeis guineensis) Leaves

  2021cites this paper
• Nitrogenases and Model Complexes in Bioorganometallic Chemistry

  2021cites this paper
• Dinitrogen binding and activation at a molybdenum–iron–sulfur cluster

  2021cites this paper
• Recent Advances in Nonprecious Metal Oxide Electrocatalysts and Photocatalysts for N2 Reduction Reaction under Ambient Condition

  2021cites this paper
• Iron Dual-atom Catalyst combine with ″vicinal nonmetallic sites″ for efficient Ammonia Synthesis

  2021cites this paper
• Rhizobium-Linked Nutritional and Phytochemical Changes Under Multitrophic Functional Contexts in Sustainable Food Systems

  2021cites this paper
• A large scaled-up monocrystalline 3R MoS2 electrocatalyst for efficient nitrogen reduction reactions

  2021cites this paper
• EDA–NOCV Calculation for Efficient N2 Binding to the Reduced Ni3S8 Complex: Estimation of Ni–N2 Intrinsic Interaction Energies

  2021cites this paper
• Ammonia Production Technologies

  2021cites this paper
• Dinitrogen Activation by a Heterometallic VFe Complex Derived from 1,1'-Bis(arylamido)vanadocene

  2020cites this paper
• Theoretical Screening of Single Atoms Supported on Two-Dimensional Nb2CN2 for Nitrogen Fixation

  2020cites this paper
• Exploration of strategies to increase the nitrogen and phosphate content of solid waste landfill soil

  2020cites this paper
• Coordination-Induced N–H Bond Weakening in a Molybdenum Pyrrolidine Complex: Isotopic Labeling Provides Insight into the Pathway for H2 Evolution

  2020cites this paper
• Terminal uranium(V)-nitride hydrogenations involving direct addition or Frustrated Lewis Pair mechanisms

  2020cites this paper
• Solvent dynamics play a decisive role in the complex formation of biologically relevant redox proteins.

  2020cites this paper
• Direct transformation of dinitrogen: synthesis of N-containing organic compounds via N−C bond formation

  2020cites this paper
• Reduction of Substrates by Nitrogenases.

  2020cites this paper
• Mo2TiC2 MXene: A Promising Catalyst for Electrocatalytic Ammonia Synthesis

  2020cites this paper
• Molecular mechanisms of electron transfer employed by native proteins and biological-inorganic hybrid systems

  2020cites this paper
• Engineering the coordination environment enables molybdenum single-atom catalyst for efficient oxygen reduction reaction

  2020cites this paper
• Determination of the N-H Bond Dissociation Free Energy in a Pyridine(diimine)molybdenum Complex Prepared by Proton-Coupled Electron Transfer.

  2020cites this paper
• Push–Pull Activation of N 2 : Coordination of Lewis Acids to Dinitrogen Complexes

  2020cites this paper
• Assessment of Density Functional Theory in Studying on the Transition States of A Diiron-mediated N--N Bond Cleavage Reaction

  2020cites this paper
• Fe doped SrWO4 with tunable band structure for photocatalytic nitrogen fixation

  2020cites this paper
• Multiphasic 1T@2H MoSe2 as a highly efficient catalyst for the N2 reduction to NH3

  2020cites this paper
• Co‐catabolism of arginine and succinate drives symbiotic nitrogen fixation

  2020cites this paper
• Recent Progress on Catalysts towards Electrocatalytic Nitrogen Reduction Reaction

  2020cites this paper
• High-Performance Electrocatalytic Conversion of N2 to NH3 Using 1T-MoS2 Anchored on Ti3C2 MXene Under Ambient Conditions.

  2020cites this paper
• Self-supporting CoMoC nanoporous catalysts for N2 reduction reaction under ambient conditions

  2020cites this paper
• 1 T-phase molybdenum sulfide nanodots enable efficient electrocatalytic nitrogen fixation under ambient conditions

  2020cites this paper
• Boosting electrosynthesis of ammonia on surface-engineered MXene Ti3C2

  2020cites this paper