Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.

Mr. Chairman, ladies and gentlemen, it is an honor to receive from the American Society of Pharmacology and Experimental Therapeutics the 1996 Otto Krayer Award sponsored by Zeneca Pharmaceutics Co. I am especially delighted to receive this award not only because of the remarkable contributions that

• Publication year

  1997

• Venue

  Journal of Pharmacology and Experimental Therapeutics

• Publication date

  1997-03-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/s0022-3565(24)36503-6PMID 9067295
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cholinergic modulation of memory in rats

  2004cited by this paper
• Neurite Outgrowth in PC12 Cells

  1999cited by this paper
• Molecular Histochemistry of Nicotinic Receptors in Human Brain

  1997cited by this paper
• The role of dendritic action potentials and Ca2+ influx in the induction of homosynaptic long-term depression in hippocampal CA1 pyramidal neurons.

  1996cited by this paper
• Nicotinic receptors in the development and modulation of CNS synapses.

  1996cited by this paper
• Hippocampal synaptic transmission enhanced by low concentrations of nicotine

  1996cited by this paper
• Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. IV. Regulation by external Ca++ of alpha-bungarotoxin-sensitive receptor function and of rectification induced by internal Mg++.

  1996influential reference
• Mapping the location of functional nicotinic and gamma-aminobutyric acidA receptors on hippocampal neurons.

  1996influential reference
• In vitro neuroprotective properties of the novel cholinergic channel activator (ChCA), ABT-418.

  1996cited by this paper
• Nicotinic acetylcholine receptors on hippocampal neurons: cell compartment-specific expression and modulatory control of channel activity.

  1996cited by this paper
• Cholinergic mechanisms : from molecular biology to clinical significance

  1996cited by this paper
• Diversity of nicotinic acetylcholine receptors in rat brain. V. alpha-Bungarotoxin-sensitive nicotinic receptors in olfactory bulb neurons and presynaptic modulation of glutamate release.

  1996influential reference
• Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands.

  1996cited by this paper
• New approach to drug therapy in Alzheimer's dementia Alfred Maelicke and Edson X. Albuquerque

  1996cited by this paper
• Ligand-gated ion channels in acutely dissociated rat hippocampal neurons with long dendrites.

  1996cited by this paper
• Alpha-conotoxin-ImI: a competitive antagonist at alpha-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons.

  1996cited by this paper
• Nicotinic responses in acutely dissociated rat hippocampal neurons and the selective blockade of fast-desensitizing nicotinic currents by lead.

  1995cited by this paper
• Nicotinic Receptor Function in the Mammalian Central Nervous System a

  1995cited by this paper
• alpha-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors.

  1995cited by this paper
• Human alpha 7 nicotinic acetylcholine receptor responses to novel ligands.

  1995cited by this paper
• Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells

  1995cited by this paper
• alpha-Bungarotoxin-sensitive hippocampal nicotinic receptor channel has a high calcium permeability.

  1995influential reference
• Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current.

  1995cited by this paper
• Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors.

  1995cited by this paper
• α-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with α7 subunits and up-regulation by chronic nicotine treatment

  1995cited by this paper
• Agonist and toxin sensitivities of ACh-evoked currents on neurons expressing multiple nicotinic ACh receptor subunits.

  1995cited by this paper
• Human α 7 nicotinic acetylcholine receptor responses to novel ligands

  1995cited by this paper
• Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons.

  1995cited by this paper
• Physostigmine, galanthamine and codeine act as 'noncompetitive nicotinic receptor agonists' on clonal rat pheochromocytoma cells.

  1995cited by this paper
• alpha-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with alpha 7 subunits and up-regulation by chronic nicotine treatment.

  1995cited by this paper
• Neuronal nicotinic receptors: function, modulation and structure

  1995influential reference
• Physostigmine and galanthamine: probes for a novel binding site on the alpha 4 beta 2 subtype of neuronal nicotinic acetylcholine receptors stably expressed in fibroblast cells.

  1994cited by this paper
• Neuronal acetylcholine receptors that bind alpha-bungarotoxin mediate neurite retraction in a calcium-dependent manner

  1994cited by this paper
• Multideterminant role of calcium in hippocampal synaptic plasticity

  1994cited by this paper
• Localization of nicotinic cholinergic receptors in rat brain: autoradiographic studies with [3H]cytisine.

  1994cited by this paper
• Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. II. The rundown and inward rectification of agonist-elicited whole-cell currents and identification of receptor subunits by in situ hybridization.

  1994influential reference
• Monoclonal antibodies FK1 and WF6 define two neighboring ligand binding sites on Torpedo acetylcholine receptor alpha-polypeptide.

  1994cited by this paper
• Nicotine-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity.

  1994cited by this paper
• 9-Aminoacridines act at a site different from that for Mg2+ in blockade of the N-methyl-D-aspartate receptor channel.

  1994cited by this paper
• A novel nicotinic agonist facilitates induction of long-term potentiation in the rat hippocampus.

  1994cited by this paper
• Homomers of alpha 8 and alpha 7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties.

  1994influential reference
• Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells.

  1994cited by this paper
• Effects of anabaseine‐related analogs on rat brain nicotinic receptor binding and on avoidance behaviors

  1994cited by this paper
• Presence of alpha-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat olfactory bulb neurons.

  1994cited by this paper
• Human alpha 7 acetylcholine receptor: cloning of the alpha 7 subunit from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional alpha 7 homomers expressed in Xenopus oocytes.

  1994cited by this paper
• Epibatidine, a potent analgetic and nicotinic agonist.

  1994cited by this paper
• α9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells

  1994influential reference
• Properties of Kv2.1 K+ channels expressed in transfected mammalian cells.

  1994cited by this paper
• Brief-lifetime, fast-inactivating ion channels account for the alpha-bungarotoxin-sensitive nicotinic response in hippocampal neurons.

  1993cited by this paper
• Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

  1993cited by this paper
• Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

  1993cited by this paper
• Effects of lobeline, a nicotinic receptor agonist, on learning and memory.

  1993cited by this paper
• Nicotinic cholinoceptor-mediated excitatory postsynaptic potentials in rat nucleus ambiguus

  1993cited by this paper
• The diversity of neuronal nicotinic acetylcholine receptors.

  1993cited by this paper
• Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs.

  1993cited by this paper
• Protease Inhibitors and Indolamines Selectively Inhibit Cholinesterases in the Histopathologic Structures of Alzheimer's Disease a

  1993cited by this paper
• A role for the nicotinic alpha-bungarotoxin receptor in neurite outgrowth in PC12 cells.

  1993cited by this paper
• Identification and functional characterization of a new agonist site on nicotinic acetylcholine receptors of cultured hippocampal neurons.

  1993cited by this paper
• Barium permeability of neuronal nicotinic receptor alpha 7 expressed in Xenopus oocytes.

  1993cited by this paper
• Mutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.

  1993cited by this paper
• A novel agonist binding site on nicotinic acetylcholine receptors.

  1993cited by this paper
• Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons

  1993influential reference
• Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes.

  1993cited by this paper
• The NMDA receptor complex

  1993cited by this paper
• A role for the nicotinic α-bungarotoxin receptor in neurite outgrowth in PC12 cells

  1993cited by this paper
• Equilibrium and kinetic study of glycine action on the N‐methyl‐D‐aspartate receptor in cultured mouse brain neurons.

  1992cited by this paper
• Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.

  1992cited by this paper
• Kinetic properties and regulation of GABAA receptor channels.

  1992cited by this paper
• 6.5 Monoclonal antibodies reveal the cellular localization and expression of cortical nicotinic and muscarinic cholinoceptors in human cerebral cortex

  1992cited by this paper
• Pharmacological properties of the homomeric alpha 7 receptor.

  1992cited by this paper
• Pharmacological properties of the homomeric α7 receptor

  1992cited by this paper
• Initial characterization of the nicotinic acetylcholine receptors in rat hippocampal neurons.

  1991cited by this paper
• A second pathway of activation of the Torpedo acetylcholine receptor channel.

  1991influential reference
• alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.

  1991cited by this paper
• Desensitization is a property of the cholinergic binding region of the nicotinic acetylcholine receptor, not of the receptor‐integral ion channel

  1991cited by this paper
• Pentameric structure and subunit stoichiometry of a neuronal nicotinic acetylcholine receptor

  1991cited by this paper
• Nicotinic cholinoceptive neurons of the frontal cortex are reduced in Alzheimer's disease.

  1991influential reference
• Postsynaptic NMDA receptor-mediated calcium accumulation in hippocampal CAl pyramidal cell dendrites

  1990cited by this paper
• alpha-Cobratoxin blocks the nicotinic acetylcholine receptor in rat hippocampal neurons.

  1990cited by this paper
• Nicotinic acetylcholine receptor superfamily of ligand-gated ion channels.

  1990cited by this paper
• Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons

  1990cited by this paper
• Immunohisto- and cytochemical localization of cortical nicotinic cholinoceptors in rat and man.

  1989cited by this paper
• The organization of behavior

  1988cited by this paper
• Structure-activity relationship of reversible cholinesterase inhibitors: activation, channel blockade and stereospecificity of the nicotinic acetylcholine receptor-ion channel complex.

  1988cited by this paper
• N-methyl-D-aspartate (NMDA) receptors are inactivated by trypsin.

  1988cited by this paper
• The neurobiology of learning and memory: elucidation of the mechanisms of cognitive dysfunction.

  1988cited by this paper
• Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

  1987cited by this paper
• Nicotine as a psychoactive drug: anxiety and pain reduction.

  1986cited by this paper
• Nicotine as a psychoactive drug: anxiety and pain reduction.

  1986cited by this paper
• The reversible cholinesterase inhibitor physostigmine has channel-blocking and agonist effects on the acetylcholine receptor-ion channel complex.

  1985cited by this paper
• Magnesium gates glutamate-activated channels in mouse central neurones

  1984influential reference
• Nicotinic acetylcholine receptors.

  1977cited by this paper

• Importance of Modulating Kynurenic Acid Metabolism—Approaches for the Treatment of Dementia

  2025cites this paper
• Longitudinal impact of cholinesterase inhibitors on cholinergic white matter integrity in mild cognitive impairment: A diffusion MRI study

  2025cites this paper
• Significance of nicotine and nicotinic acetylcholine receptors in Parkinson’s disease

  2025cites this paper
• α7 nicotinic acetylcholine receptors induce long‐term synaptic enhancement in the dorsal but not ventral hippocampus

  2024cites this paper
• Crisis in the gut: navigating gastrointestinal challenges in Gulf War Illness with bioengineering

  2024cites this paper
• Nicotine Motivated Behavior in C. elegans

  2024cites this paper
• Mapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI)

  2023cites this paper
• The Alpha 7 Nicotinic Acetylcholine Receptor Does Not Affect Neonatal Brain Injury

  2022cites this paper
• The Neuromodulatory Role of the Noradrenergic and Cholinergic Systems and Their Interplay in Cognitive Functions: A Focused Review

  2022cites this paper
• Exploring the molecular interactions of Galantamine with human Transferrin: In-silico and in vitro insight

  2021cites this paper
• Nicotinic Acetylcholine Receptor α7 Subunit Is an Essential Regulator of Seizure Susceptibility

  2021cites this paper
• The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice

  2021cites this paper
• A review on advances of treatment modalities for Alzheimer's disease.

  2021cites this paper
• The Role of CaMKII and ERK Signaling in Addiction

  2021cites this paper
• Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator BNC375

  2020cites this paper
• Snake C-type lectin-like proteins inhibit nicotinic acetylcholine receptors

  2020cites this paper
• Behavioral Pharmacology of the Cholinergic System

  2020cites this paper
• Endogenous Cholinergic Signaling Modulates Sound-Evoked Responses of the Medial Nucleus of the Trapezoid Body

  2020cites this paper
• Acetylcholine Imaging in Psychosis

  2020cites this paper
• Upregulated nicotinic ACh receptor signaling contributes to intestinal stem cell function through activation of Hippo and Notch signaling pathways.

  2020cites this paper
• Involvement of Nicotinic Receptors in Working Memory Function.

  2020cites this paper
• Activators of α7 nAChR as Potential Therapeutics for Cognitive Impairment.

  2020cites this paper
• Decreased levels of circulating trimethylamine N-oxide alleviate cognitive and pathological deterioration in transgenic mice: a potential therapeutic approach for Alzheimer’s disease

  2019cites this paper
• Targeting the α4β2- and α7-Subtypes of Nicotinic Acetylcholine Receptors for Smoking Cessation Medication Development

  2019cites this paper
• Frontiers in PET imaging of the vulnerable atherosclerotic plaque.

  2019cites this paper
• Nicotine is neuroprotective to neonatal neurons of sympathetic ganglion in rat.

  2019cites this paper
• Neuromuscular Physiology and Pharmacology

  2019cites this paper
• Phytochemical constituents from Galanthus alpinus Sosn. var. alpinus and their anticholinesterase activities

  2019cites this paper
• DEVELOPMENT OF A TRANSLATIONAL MODEL OF CO-USE OF ALCOHOL AND NICOTINE FOR TESTING POTENTIAL PHARMACOTHERAPIES

  2019cites this paper
• Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays

  2019cites this paper
• Massive expansion and diversity of nicotinic acetylcholine receptors in lophotrochozoans

  2019cites this paper
• Comparison of cholinesterase inhibitor safety in real-world practice

  2019cites this paper
• RETRACTED: Nicotinic acetylcholine receptor α7 subunit maybe a risk factor of seizure susceptibility.

  2019cites this paper
• Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway.

  2019cites this paper
• Does kynurenic acid act on nicotinic receptors? An assessment of the evidence

  2019cites this paper
• P4‐218: Q134R: NOVEL SMALL CHEMICAL COMPOUND WITH NFAT INHIBITORY PROPERTIES AMELIORATES SYNAPTIC DEFICITS IN A MOUSE MODEL OF ALZHEIMER'S DISEASE

  2018cites this paper
• &agr;7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet–Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling

  2018cites this paper
• Beyond the Channel: Metabotropic Signaling by Nicotinic Receptors.

  2018cites this paper
• Alpha 7 nicotinic receptors attenuate neurite development through calcium activation of calpain at the growth cone

  2018cites this paper
• P4‐217: LEPTIN REDUCES PATHOLOGY AND IMPROVES ADULT NEUROGENESIS IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE

  2018cites this paper
• The cholinergic anti‐inflammatory pathway: an innovative treatment strategy for respiratory diseases and their comorbidities

  2018cites this paper
• Relevance of Alternative Routes of Kynurenic Acid Production in the Brain

  2018cites this paper
• cAMP, cGMP and Amyloid β: Three Ideal Partners for Memory Formation.

  2018cites this paper
• Galantamine Derivatives as Acetylcholinesterase Inhibitors: Docking, Design, Synthesis, and Inhibitory Activity

  2018cites this paper
• The Coordinated Activities of nAChR and Wnt Signaling Regulate Intestinal Stem Cell Function in Mice

  2018cites this paper
• Expression and Function of Alpha 3 and Beta 2 Neuronal Nicotinic Acetylcholine Receptor Subunits in HEK-293 Cells

  2018cites this paper
• Neurotoxicity fingerprinting of venoms using on‐line microfluidic AChBP profiling

  2018cites this paper
• Low Serum Tryptophan Levels as an Indicator of Global Cognitive Performance in Nondemented Women over 50 Years of Age

  2018cites this paper
• P4‐214: SUPPLEMENTATION WITH A NOVEL LIPID EXTRACT IMPROVES FRONTAL LOBE LINKED COGNITIVE DEFICITS IN AN AGED BEAGLE MODEL OF ALZHEIMER'S DISEASE

  2018cites this paper
• High-Throughput Virtual Screening Molecular Docking Software for Students and Educators

  2018cites this paper
• UC Office of the President Recent Work Title Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease : Cellular and Mechanistic Insights Permalink

  2017cites this paper
• Connection of Nicotine to Diet-Induced Obesity and Non-Alcoholic Fatty Liver Disease: Cellular and Mechanistic Insights

  2017cites this paper
• The potential use of rabies virus glycoprotein-derived peptides to facilitate drug delivery into the central nervous system: a mini review

  2017cites this paper
• Alpha-7-nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine plus High-Fat Diet-Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling

  2017cites this paper
• Role of Non-Coding Genetic Risk Variation in CHRNA5-CHRNA3-CHRNAB4 Cluster on Chromosome 15q21 in Addiction, Lung Cancer, Learning and Memory

  2017cites this paper
• Docking‐based design and synthesis of galantamine–camphane hybrids as inhibitors of acetylcholinesterase

  2017cites this paper
• Canagliflozin prevents scopolamine-induced memory impairment in rats: Comparison with galantamine hydrobromide action.

  2017cites this paper
• A G protein‐coupled α7 nicotinic receptor regulates signaling and TNF‐α release in microglia

  2017cites this paper
• Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.

  2017cites this paper
• Characterization of Sex Differences in the Reinforcing Effects of Nicotine

  2017cites this paper
• Understanding the Bases of Function and Modulation of α7 Nicotinic Receptors: Implications for Drug Discovery

  2016cites this paper
• Effects of Alcohol on Nicotinic Acetylcholine Receptors and Impact on Addiction

  2016cites this paper
• Kinetics of Synaptic Current

  2016cites this paper
• Docking‐based Design of Galantamine Derivatives with Dual‐site Binding to Acetylcholinesterase

  2016cites this paper
• Peptides from puff adder Bitis arietans venom, novel inhibitors of nicotinic acetylcholine receptors.

  2016cites this paper
• MECHANISMS OF GATING AND MODULATION IN THE FAMILY OF CYS-LOOP RECEPTORS

  2016cites this paper
• Deficits in GABAA receptor function and working memory in non-smokers with schizophrenia.

  2016cites this paper
• Analyse descriptive de la prise en charge des patients atteints de la maladie d'Alzheimer au sein de l'unité de soins spécialisée du Centre hospitalier de Beauvais

  2015cites this paper
• Nicotinic and muscarinic acetylcholine receptors shape ganglion cell response properties.

  2015cites this paper
• The immunomodulation of nicotinic acetylcholine receptor subunits in Zhikong scallop Chlamys farreri.

  2015cites this paper
• and -Insensitive Nociceptors of the Rat DRG Nicotinic AChR in Subclassified Capsaicin-Sensitive

  2015cites this paper
• Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors

  2015cites this paper
• Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity.

  2015cites this paper
• Molecular Docking Study on Galantamine Derivatives as Cholinesterase Inhibitors

  2015cites this paper
• Chick Sympathetic Ganglia by PGE Receptor Subtypes and Synaptic Transmission in Differential Modulation of Nicotinic Acetylcholine

  2015cites this paper
• of Excitotoxic Currents at Physiological Temperatures

  2015cites this paper
• Nicotinic Cholinergic Mechanisms in Alzheimer's Disease.

  2015cites this paper
• TEN Nicotinic Cholinergic Mechanisms in Alzheimer ' s Disease

  2015cites this paper
• in the Rat Hippocampus Nicotinic Cholinergic Excitation of CA1 Interneurons NMDA and AMPA Receptors Contribute to the

  2015cites this paper
• The effect of galantamine on brain atrophy rate in subjects with mild cognitive impairment is modified by apolipoprotein E genotype: post-hoc analysis of data from a randomized controlled trial

  2014cites this paper
• The Novel α7β2-Nicotinic Acetylcholine Receptor Subtype Is Expressed in Mouse and Human Basal Forebrain: Biochemical and Pharmacological Characterization

  2014cites this paper
• Smoking Effects in the Human Nervous System

  2014cites this paper
• Targeting the interaction between fatty acid ethanolamides and nicotinic receptors: therapeutic perspectives.

  2014cites this paper
• Alterations in the cholinergic system of brain stem neurons in a mouse model of Rett syndrome.

  2014cites this paper
• The nicotinic cholinergic system is affected in rats with delayed carbon monoxide encephalopathy.

  2014cites this paper
• Targeting the α7 nicotinic acetylcholine receptor to prevent progressive dementia and improve cognition in adults with Down's syndrome.

  2014cites this paper
• Nicotine Elevated Intracellular Ca2+ in Rat Airway Smooth Muscle Cells via Activating and Up-Regulating α7-Nicotinic Acetylcholine Receptor

  2014cites this paper
• The Novel a 7 b 2-Nicotinic Acetylcholine Receptor Subtype Is Expressed in Mouse and Human Basal Forebrain : Biochemical and Pharmacological Characterization s

  2014cites this paper
• Nicotinic Acetylcholine Receptors in Autism Spectrum Disorders: Therapeutic Implications

  2014cites this paper
• Maintenance of Neuron Activity by Homeostatic Alterations in Receptors and Ion Channels in a Rett Syndrome Mouse Model

  2014cites this paper
• Perinatal Hypoxia-Ischemia Reduces α7 Nicotinic Receptor Expression and Selective α7 Nicotinic Receptor Stimulation Suppresses Inflammation and Promotes Microglial Mox Phenotype

  2014cites this paper
• Alkaloids and Inhibitory Effects Against Enzymes Linked to Neurodegenerative Diseases (Physostigmine, Galanthamine, Huperzine, etc.)

  2013cites this paper
• The influence of inhibiting or stimulating the expression of the α3 subunit of the nicotinic receptor in SH-SY5Y cells on levels of amyloid-β peptide and β-secretase.

  2013cites this paper
• Protective effect of Heracleum persicum alcoholic extract against diazinon-induced spatial memory impairment of rat

  2013cites this paper
• To Design Novel Lead Molecules for the Enzyme, AChE Associated with Alzheimer's Disease

  2013cites this paper
• γ‐Aminobutyric acid type a receptor inhibition triggers a nicotinic neuroprotective mechanism

  2013cites this paper
• Targeting alpha-7 nicotinic neurotransmission in schizophrenia: a novel agonist strategy.

  2013cites this paper
• A Double-blind, Placebo-Controlled Study of the Impact of Galantamine on Anterograde Memory Impairment During Electroconvulsive Therapy

  2013cites this paper
• Prevention of Brain Disorders by Nicotine

  2013cites this paper
• Cholinergic modulation by opioid receptor ligands: potential application to Alzheimer's disease.

  2013cites this paper