Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Biological Psychiatry

• Publication date

  2003-12-15

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/S0006-3223(03)00183-5PMID 14675805
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• SPECT imaging of dopamine and serotonin transporters with [123I]β-CIT. Binding kinetics in the human brain

  2005cited by this paper
• β-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo

  2005cited by this paper
• Obsessive-compulsive disorder

  2002cited by this paper
• In vitro and in vivo characterisation of [11C]-DASB: a probe for in vivo measurements of the serotonin transporter by positron emission tomography.

  2002cited by this paper
• Adults with early-onset obsessive-compulsive disorder.

  2001cited by this paper
• Childhood-onset obsessive-compulsive disorder: a tic-related subtype of OCD?

  2001cited by this paper
• [123I] β-CIT and single photon emission computed tomography reveal reduced brain serotonin transporter availability in bulimia nervosa

  2001cited by this paper
• Predictors of response to pharmacotherapy with citalopram in obsessive-compulsive disorder

  2001cited by this paper
• Sex differences in [123I]β‐CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers

  2001cited by this paper
• Imaging serotonin and dopamine transporters with 123I-beta-CIT SPECT: binding kinetics and effects of normal aging.

  2000cited by this paper
• Age-related decline in central serotonin transporter availability with [(123)I]beta-CIT SPECT.

  2000cited by this paper
• Elevated central serotonin transporter binding availability in acutely abstinent cocaine-dependent patients.

  2000cited by this paper
• [123I]-beta-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder.

  2000cited by this paper
• 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand.

  2000cited by this paper
• Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder.

  2000cited by this paper
• [123I]-β-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder

  2000cited by this paper
• Age-related decline in central serotonin transporter availability with [123I]β-CIT SPECT

  2000cited by this paper
• Pharmacotherapy of obsessive‐compulsive disorder: experience with the selective serotonin reuptake inhibitors

  2000cited by this paper
• Obsessive-compulsive disorder: diagnosis and treatment.

  1999cited by this paper
• In vivo visualization of serotonin transporters in the human brain during fluoxetine treatment.

  1999cited by this paper
• Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography.

  1998cited by this paper
• Estrogen-serotonin interactions: implications for affective regulation.

  1998cited by this paper
• Reduced brain serotonin transporter availability in major depression as measured by [123I]-2β-carbomethoxy-3β-(4-iodophenyl)tropane and single photon emission computed tomography

  1998cited by this paper
• In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates.

  1998cited by this paper
• Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder

  1998cited by this paper
• Reduced central serotonin transporters in alcoholism.

  1998cited by this paper
• Is juvenile obsessive-compulsive disorder a developmental subtype of the disorder? A review of the pediatric literature.

  1998cited by this paper
• Tourette's syndrome

  1998cited by this paper
• SKID. Strukturiertes Klinisches Interview für DSM-IV. Achse I und II. Handanweisung

  1997cited by this paper
• N-substituted analogs of 2 beta-carbomethoxy-3 beta- (4'-iodophenyl)tropane (beta-CIT) with selective affinity to dopamine or serotonin transporters in rat forebrain.

  1996cited by this paper
• N-Substituted Analogs of 2β-Carbomethoxy-3β-(4‘-iodophenyl)tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain

  1996cited by this paper
• N-Substituted Analogues of 2β-Carbomethoxy-3β-(4′-iodophenyl) tropane (β-CIT) with Selective Affinity to Dopamine or Serotonin Transporters in Rat Forebrain.

  1996cited by this paper
• Serotonergic function in obsessive-compulsive disorder

  1996cited by this paper
• Diagnostic and Statistical Manual of Mental Disorders, 4th Ed.

  1994cited by this paper
• Graphical, Kinetic, and Equilibrium Analyses of in vivo [123I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

  1994cited by this paper
• Visualizing Dopamine and Serotonin Transporters in the Human Brain with the Potent Cocaine Analogue [125I]RTI‐55: In Vitro Binding and Autoradiographic Characterization

  1994cited by this paper
• The Yale-Brown Obsessive-Compulsive Scale: measures of internal consistency.

  1994cited by this paper
• Initial experience with single-photon emission tomography using iodine-123-labelled 2 beta-carbomethoxy-3 beta-(4-iodophenyl) tropane in human brain.

  1993cited by this paper
• Initial experience with single-photon emission tomography using iodine-123-labelled 2 β-carbomethoxy-3β-(4-iodophenyl)tropane in human brain

  1993cited by this paper
• SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates

  1993cited by this paper
• Quantitative electroencephalographic subtyping of obsessive-compulsive disorder.

  1993cited by this paper
• Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

  1993cited by this paper
• High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brain

  1992cited by this paper
• Toward a neuroanatomy of obsessive-compulsive disorder.

  1992cited by this paper
• Pharmacotherapy of obsessive compulsive disorder.

  1992cited by this paper
• Serotonergic function in obsessive-compulsive disorder. Behavioral and neuroendocrine responses to oral m-chlorophenylpiperazine and fenfluramine in patients and healthy volunteers.

  1992cited by this paper
• The role of serotonin and dopamine in the pathophysiology of obsessive compulsive disorder

  1992cited by this paper
• Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT.

  1991cited by this paper
• Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine.

  1990cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability.

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale. II. Validity.

  1989cited by this paper
• The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability

  1989cited by this paper
• Treatment of childhood obsessive compulsive disorder with clomipramine and desmethylimipramine: a double-blind crossover comparison.

  1988cited by this paper
• The potential role of serotonin reuptake inhibitors in the treatment of obsessive compulsive disorder.

  1988cited by this paper
• An inventory for measuring depression.

  1961cited by this paper

• Rewiring the OCD brain: Insights beyond cortico-striatal networks.

  2025cites this paper
• Serotonergic underpinnings of obsessive‐compulsive disorder: A systematic review and meta‐analysis of neuroimaging findings

  2024cites this paper
• Towards zebrafish models to unravel translational insights of obsessive-compulsive disorder: a neurobehavioral perspective.

  2024cites this paper
• The Zebrafish for Preclinical Psilocybin Research.

  2023cites this paper
• Perinatal Obsessive–Compulsive Disorder: Epidemiology, Phenomenology, Etiology, and Treatment

  2022cites this paper
• Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [123I]ADAM and Heart Rate Variability Measurement

  2022cites this paper
• Pharmacotherapeutic Strategies and New Targets in OCD.

  2021cites this paper
• A nationwide nested case‐control study of new‐onset obsessive‐compulsive disorder following antipsychotics use in schizophrenia

  2021cites this paper
• Animal Models for OCD Research.

  2021cites this paper
• Obsessive-compulsive disorder.

  2020cites this paper
• The serotonergic system in obsessive-compulsive disorder

  2020cites this paper
• Neuroimaging of Obsessive-Compulsive Disorder: Insights into Serotonergic Mechanisms

  2020cites this paper
• Genetic, epigenetic, and environmental factors in serotonin-associated disease condition

  2020cites this paper
• A Psycho-Behavioral Perspective on Modelling Obsessive-Compulsive Disorder (OCD) in Animals: The Role of Context.

  2019cites this paper
• Évaluation de la flexibilité cognitive dans le trouble obsessionnel compulsif : étude de la validité de deux auto-questionnaires comparés à une tâche expérimentale

  2019influential citation
• Neuroimaging findings in obsessive–compulsive disorder: A narrative review to elucidate neurobiological underpinnings

  2019influential citation
• Resting-state functional connectivity alterations in obsessive-compulsive disorder

  2019cites this paper
• S‐ketamine reduces marble burying behaviour: Involvement of ventromedial orbitofrontal cortex and AMPA receptors

  2019cites this paper
• Serotonin transporter binding is increased in Tourette syndrome with Obsessive Compulsive Disorder

  2019cites this paper
• Altered serotonergic and GABAergic neurotransmission in a mice model of obsessive‐compulsive disorder

  2018cites this paper
• Higher serotonin transporter availability in early‐onset obsessive–compulsive disorder patients undergoing escitalopram treatment: A [11C]DASB PET study

  2018cites this paper
• Efeito tipo-anticompulsivo agudo da Ketamina: envolvimento do córtex orbitofrontal e dos receptores AMPA

  2018cites this paper
• Brain serotonin synthesis capacity in obsessive-compulsive disorder: effects of cognitive behavioral therapy and sertraline

  2018cites this paper
• Obsessive-Compulsive Disorder

  2018cites this paper
• A review of the role of serotonin system genes in obsessive‐compulsive disorder

  2017influential citation
• Different patterns of 5-HT receptor and transporter dysfunction in neuropsychiatric disorders – a comparative analysis of in vivo imaging findings

  2016cites this paper
• Effect of Gonadal Hormones on Neurotransmitters Implicated in the Pathophysiology of Obsessive-Compulsive Disorder: A Critical Review

  2016cites this paper
• Etiopathology and neurobiology of obsessive-compulsive disorder: focus on biological rhythms and chronotherapy

  2016cites this paper
• Polypharmacy for Obsessive-Compulsive Symptoms in Schizophrenia: Augmentation and Combination Strategies

  2015cites this paper
• Motivation and value influences in the relative balance of goal-directed and habitual behaviours in obsessive-compulsive disorder

  2015cites this paper
• Serotonin: from sensory processing to schizophrenia using an electrophysiological method.

  2015cites this paper
• 61. Obsessive compulsive disorder

  2015cites this paper
• Increased orbitofrontal cortex activation associated with "pro-obsessive" antipsychotic treatment in patients with schizophrenia.

  2015influential citation
• Cannabinoids and obsessive-compulsive disorder

  2015cites this paper
• Altered serotonin transporter binding potential in patients with obsessive-compulsive disorder under escitalopram treatment: [11C]DASB PET study

  2015influential citation
• Imaging Studies of Anxiety Disorders

  2015cites this paper
• Effects of Antipsychotic Treatment on Obsessive-Compulsive Symptoms

  2015cites this paper
• OCD: Serotonergic mechanisms

  2014cites this paper
• Comorbid Obsessive-Compulsive Symptoms in Schizophrenia: Insight into Pathomechanisms Facilitates Treatment

  2014cites this paper
• Second Generation Antipsychotic-Induced Obsessive-Compulsive Symptoms in Schizophrenia: A Review of the Experimental Literature

  2014cites this paper
• An updated review of antidepressants with marked serotonergic effects in obsessive–compulsive disorder

  2014cites this paper
• Obsessive–Compulsive Disorder

  2014cites this paper
• Dopaminergic control of cognitive flexibility in humans and animals

  2013cites this paper
• Moving the Brain: Neuroimaging Motivational Changes of Deep Brain Stimulation in Obsessive-Compulsive Disorder

  2013cites this paper
• Transcranial sonography in obsessive-compulsive disorder.

  2013cites this paper
• Obsessive-Compulsive Syndromes in Schizophrenia: A Case for Polypharmacy?

  2013cites this paper
• Comorbid obsessive-compulsive symptoms in schizophrenia: contributions of pharmacological and genetic factors

  2013cites this paper
• Neuroimaging of serotonin system in anxiety disorders.

  2012cites this paper
• Association between somatization subscale score and serotonin transporter availability in healthy volunteers—a single photon emission computed tomography study with [123I] ADAM

  2012cites this paper
• Serotonin 2A receptor, serotonin transporter and dopamine transporter alterations in dogs with compulsive behaviour as a promising model for human obsessive-compulsive disorder.

  2012cites this paper
• Clozapine-Induced Obsessive-Compulsive Symptoms in Schizophrenia: A Critical Review

  2012cites this paper
• Polymorphisms in the glutamate transporter gene SLC1A1 and obsessive–compulsive symptoms induced by second-generation antipsychotic agents

  2012cites this paper
• Neurotrophic factors in obsessive-compulsive disorder.

  2012cites this paper
• The serotonin transporter availability in untreated early-onset and late-onset patients with obsessive-compulsive disorder.

  2011cites this paper
• Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder.

  2011cites this paper
• Central serotonin transporter levels are associated with stress hormone response and anxiety

  2011cites this paper
• Neurobiologie der Zwangsstörung

  2011cites this paper
• Brain Regional-[ 11 C ] Methyl-L-Tryptophan Trapping in Medication-Free Patients With Obsessive-Compulsive Disorder

  2011cites this paper
• Antiserotonergic antipsychotics are associated with obsessive–compulsive symptoms in schizophrenia

  2011cites this paper
• The neurobiology of repetitive behavior: …and men.

  2011cites this paper
• Cognitive flexibility in obsessive-compulsive disorder and major depression: Functional neuroimaging studies on reversal learning and task switching

  2011cites this paper
• Brain Regional (cid:2) -[ 11 C]Methyl- L -Tryptophan Trapping in Medication-Free Patients With Obsessive-Compulsive Disorder

  2011cites this paper
• Reduced serotonin transporter binding in the insular cortex in patients with obsessive-compulsive disorder: A [11C]DASB PET study

  2010cites this paper
• The serotonergic system in obsessive-compulsive disorder.

  2010cites this paper
• The association between the harm avoidance subscale of the Tridimensional Personality Questionnaire and serotonin transporter availability in the brainstem of male volunteers.

  2010cites this paper
• Understanding deep brain stimulation in obsessive compulsive disorder: A preclinical study into the mechanism of action and behaviour

  2010cites this paper
• Low serotonergic function and its normalization by treatment with sertraline in obsessive-compulsive disorder--an auditory evoked potential study.

  2010cites this paper
• Olanzapine in male and female adolescent patients with schizophrenia and related disorders: minor sex differences in outcomes.

  2010cites this paper
• Dissociation of decisions in ambiguous and risky situations in obsessive-compulsive disorder.

  2010cites this paper
• Cortical GABA, Striatal Dopamine and Midbrain Serotonin as the Key Players in Compulsive and Anxiety Disorders - Results from In Vivo Imaging Studies

  2010cites this paper
• Diencephalic serotonin transporter availability predicts both transporter occupancy and treatment response to sertraline in obsessive-compulsive checkers.

  2009cites this paper
• Assessing the validity of current mouse genetic models of obsessive–compulsive disorder

  2009cites this paper
• The Role of Cingulate Cortex Dysfunction in Obsessive– Compulsive Disorder

  2009cites this paper
• In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders.

  2009cites this paper
• Neurobiologie der Zwangsstörung

  2009cites this paper
• Changes in Thalamus–Hypothalamus Serotonin Transporter Availability during Clomipramine Administration in Patients with Obsessive–Compulsive Disorder

  2008cites this paper
• Mechanisms of Dopaminergic and Serotonergic Neurotransmission in Tourette Syndrome: Clues from an In Vivo Neurochemistry Study with PET

  2008cites this paper
• Role of serotonin in obsessive-compulsive disorder

  2008influential citation
• Loudness Dependence of Auditory Evoked Potentials as Indicator of Central Serotonergic Neurotransmission: Simultaneous Electrophysiological Recordings and In Vivo Microdialysis in the Rat Primary Auditory Cortex

  2008cites this paper
• In vivo PET study of 5HT2A serotonin and D2 dopamine dysfunction in drug-naive obsessive-compulsive disorder

  2008influential citation
• 123I-ADAM SPECT imaging of serotonin transporter binding in patients with night eating syndrome: a preliminary report.

  2008cites this paper
• Serotoninergic mechanisms in the treatment of obsessive-compulsive disorder.

  2008cites this paper
• [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects.

  2007cites this paper
• [Neuroimaging and the neurobiology of obsessive-compulsive disorder].

  2007cites this paper
• Reduced availability of serotonin transporters in obsessive-compulsive disorder correlates with symptom severity – a [11C]DASB PET study

  2007cites this paper
• Reduced midbrain‐pons serotonin transporter binding in patients with obsessive–compulsive disorder

  2007cites this paper
• [123I]-β-CIT SPECT Imaging Shows Reduced Thalamus–Hypothalamus Serotonin Transporter Availability in 24 Drug-Free Obsessive-Compulsive Checkers

  2007influential citation
• Association between serotonin transporter availability and hostility scores in healthy volunteers - a single photon emission computed tomography study with [(123)I] ADAM.

  2007cites this paper
• [123I] ADAM brainstem binding correlates with the loudness dependence of auditory evoked potentials

  2007cites this paper
• Neurobiology and Pharmacotherapy of Obsessive-Compulsive Disorder

  2007cites this paper
• Themenschwerpunkt: Die Neurobiologie der Zwangsstörungen

  2007cites this paper
• Neurobiology of Obsessive-Compulsive Disorder: Serotonin and Beyond

  2007cites this paper
• Glutamatergic dysfunction--newer targets for anti-obsessional drugs.

  2007cites this paper
• Neurobiologische Korrelate der Zwangsstörungen - Aktuelle Befunde zur funktionellen Bildgebung

  2007cites this paper
• Serotonin transporter binding after recovery from eating disorders

  2007cites this paper
• Neuroimaging of the Serotonin Transporter: Possibilities and Pitfalls.

  2006cites this paper
• Understanding Obsessive–Compulsive Disorder: Focus on Decision Making

  2006cites this paper
• Investigating the molecular aetiology of Obsessive-compulsive disorder (OCD) and clinically-defined subsets of OCD

  2006cites this paper
• Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder.

  2006cites this paper
• Inhibition of serotonin transport by (+)McN5652 is noncompetitive.

  2006cites this paper