The tumor suppressor activity of the lysyl oxidase propeptide reverses the invasive phenotype of Her-2/neu-driven breast cancer.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Cancer Research

• Publication date

  2007-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1158/0008-5472.CAN-06-3867PMID 17283144
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The Propeptide Domain of Lysyl Oxidase Induces Phenotypic Reversion of Ras-transformed Cells*

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• Expression Analysis of Recombinant Lysyl Oxidase (LOX) in Myofibroblastlike Cells

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  2002cited by this paper
• Ras and TGFβ cooperatively regulate epithelial cell plasticity and metastasis

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• A fluorometric assay for detection of lysyl oxidase enzyme activity in biological samples.

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• Inactivation of the Lysyl Oxidase Gene Lox Leads to Aortic Aneurysms, Cardiovascular Dysfunction, and Perinatal Death in Mice

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• A molecular role for lysyl oxidase in breast cancer invasion.

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• The Role of c-erbB-2/HER2/neu in Breast Cancer Progression and Metastasis

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• Down-regulation of Lysyl Oxidase-induced Tumorigenic Transformation in NRK-49F Cells Characterized by Constitutive Activation of Ras Proto-oncogene*

  2001cited by this paper
• Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN.

  2001cited by this paper
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• Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases

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• Recent developments in breast cancer therapy.

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• Production of high-titer helper-free retroviruses by transient transfection.

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  1992cited by this paper
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  1991cited by this paper
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  1991cited by this paper
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