Functional dissection of the apicomplexan glideosome molecular architecture.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Cell Host and Microbe

• Publication date

  2010-10-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.chom.2010.09.002PMID 20951968
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008influential reference
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  2006cited by this paper
• Identification of the membrane receptor of a class XIV myosin in Toxoplasma gondii

  2004influential reference
• The glideosome: a molecular machine powering motility and host-cell invasion by Apicomplexa.

  2004cited by this paper
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  2002influential reference
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  1997cited by this paper
• Complementation of a Toxoplasma gondii ROP1 knock-out mutant using phleomycin selection.

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• Restriction enzyme-mediated integration elevates transformation frequency and enables co-transfection of Toxoplasma gondii.

  1995cited by this paper
• Freeze fracture study of the pellicle of an eimerian sporozoite (Protozoa, Coccidia).

  1978influential reference

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