Dual specificity phosphatase 15 regulates Erk activation in Schwann cells

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Neurochemistry

• Publication date

  2017-01-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/jnc.13911PMID 27891578PMCID PMC5250571
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intracellular signaling pathway regulation of myelination and remyelination in the CNS.

  2016cited by this paper
• ERK1/2 Activation in Preexisting Oligodendrocytes of Adult Mice Drives New Myelin Synthesis and Enhanced CNS Function

  2016cited by this paper
• Zeb2 is essential for Schwann cell differentiation, myelination and nerve repair

  2016cited by this paper
• Schwann cells and their transcriptional network: Evolution of key regulators of peripheral myelination.

  2016cited by this paper
• Kif13b Regulates PNS and CNS Myelination through the Dlg1 Scaffold

  2016cited by this paper
• The Dual‐specificity phosphatase Dusp15 is regulated by Sox10 and Myrf in Myelinating Oligodendrocytes

  2016cited by this paper
• Zeb2 Recruits HDAC-NuRD to Inhibit Notch and Controls Schwann Cell Differentiation and Remyelination

  2016cited by this paper
• Strength of ERK1/2 MAPK Activation Determines Its Effect on Myelin and Axonal Integrity in the Adult CNS

  2016influential reference
• Molecular control of the neural crest and peripheral nervous system development.

  2015cited by this paper
• Differential Sox10 genomic occupancy in myelinating glia

  2015cited by this paper
• Molecular signaling mechanisms of axon–glia communication in the peripheral nervous system

  2015cited by this paper
• Dynamic Regulation of Schwann Cell Enhancers after Peripheral Nerve Injury*

  2015cited by this paper
• Soluble neuregulin-1 modulates disease pathogenesis in rodent models of Charcot-Marie-Tooth disease 1A

  2014cited by this paper
• Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

  2014cited by this paper
• mTORC1 controls PNS myelination along the mTORC1-RXRγ-SREBP-lipid biosynthesis axis in Schwann cells.

  2014cited by this paper
• Loss of Glial Neurofascin155 Delays Developmental Synapse Elimination at the Neuromuscular Junction

  2014cited by this paper
• Mechanisms regulating the development of oligodendrocytes and central nervous system myelin.

  2014cited by this paper
• Sox appeal – Sox10 attracts epigenetic and transcriptional regulators in myelinating glia

  2013cited by this paper
• Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

  2013cited by this paper
• MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes

  2013cited by this paper
• Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation.

  2013cited by this paper
• The Transcription Factors Sox10 and Myrf Define an Essential Regulatory Network Module in Differentiating Oligodendrocytes

  2013cited by this paper
• Multiplex Genome Engineering Using CRISPR/Cas Systems

  2013cited by this paper
• Playing the Field: Sox10 Recruits Different Partners to Drive Central and Peripheral Myelination

  2013cited by this paper
• Specification of Macroglia by Transcription Factors: Schwann Cells

  2013cited by this paper
• Distal enhancers upstream of the Charcot-Marie-Tooth type 1A disease gene PMP22.

  2012cited by this paper
• Aging of myelinating glial cells predominantly affects lipid metabolism and immune response pathways

  2012cited by this paper
• The MMP-9/TIMP-1 Axis Controls the Status of Differentiation and Function of Myelin-Forming Schwann Cells in Nerve Regeneration

  2012cited by this paper
• Identification of VHY/Dusp15 as a Regulator of Oligodendrocyte Differentiation through a Systematic Genomics Approach

  2012influential reference
• Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system.

  2012cited by this paper
• Erbin Is Required for Myelination in Regenerated Axons after Injury

  2012cited by this paper
• Axonal regulation of Schwann cell ensheathment and myelination

  2012cited by this paper
• Genome-wide analysis of EGR2/SOX10 binding in myelinating peripheral nerve

  2012cited by this paper
• c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

  2012cited by this paper
• A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo.

  2012influential reference
• Myelin Gene Regulatory Factor Is Required for Maintenance of Myelin and Mature Oligodendrocyte Identity in the Adult CNS

  2012cited by this paper
• Molecular mechanisms regulating myelination in the peripheral nervous system.

  2012cited by this paper
• Regulation of the PMP22 Gene through an Intronic Enhancer

  2011cited by this paper
• Specific functions for ERK/MAPK signaling during PNS development.

  2011cited by this paper
• Quantitative and Integrative Proteome Analysis of Peripheral Nerve Myelin Identifies Novel Myelin Proteins and Candidate Neuropathy Loci

  2011cited by this paper
• Transcriptional profiling of the injured sciatic nerve of mice carrying the Wld(S) mutant gene: Identification of genes involved in neuroprotection, neuroinflammation, and nerve regeneration

  2010cited by this paper
• Nrg1/ErbB signaling networks in Schwann cell development and myelination.

  2010cited by this paper
• Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage

  2010cited by this paper
• Regulation of peripheral myelination by Src-like kinases.

  2010cited by this paper
• Activation of Krox20 gene expression by Sox10 in myelinating Schwann cells

  2010cited by this paper
• Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities.

  2010cited by this paper
• Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination

  2010cited by this paper
• SCAP is required for timely and proper myelin membrane synthesis

  2009cited by this paper
• Induction of Myelin Protein Zero by Early Growth Response 2 through Upstream and Intragenic Elements*

  2009cited by this paper
• Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination.

  2009cited by this paper
• The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

  2009cited by this paper
• Erbin regulates NRG1 signaling and myelination

  2009cited by this paper
• Increase of MCP‐1 (CCL2) in myelin mutant Schwann cells is mediated by MEK‐ERK signaling pathway

  2008influential reference
• Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.

  2008cited by this paper
• Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

  2008cited by this paper
• Molecular mechanisms of node of Ranvier formation.

  2008cited by this paper
• The molecular machinery of myelin gene transcription in Schwann cells

  2008cited by this paper
• Systematic identification of SH3 domain‐mediated human protein–protein interactions by peptide array target screening

  2007cited by this paper
• Interactions of Sox10 and Egr2 in myelin gene regulation.

  2007cited by this paper
• The transcription factor Yin Yang 1 is essential for oligodendrocyte progenitor differentiation.

  2007cited by this paper
• SREBP-1c expression in Schwann cells is affected by diabetes and nutritional status.

  2007cited by this paper
• In vivo detection of Egr2 binding to target genes during peripheral nerve myelination

  2006cited by this paper
• Control of myelination in Schwann cells: a Krox20 cis‐regulatory element integrates Oct6, Brn2 and Sox10 activities

  2006cited by this paper
• Analysis of congenital hypomyelinating Egr2Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination.

  2005influential reference
• Nab proteins are essential for peripheral nervous system myelination

  2005cited by this paper
• Regulation of cholesterol/lipid biosynthetic genes by Egr2/Krox20 during peripheral nerve myelination

  2005cited by this paper
• VHY, a Novel Myristoylated Testis-restricted Dual Specificity Protein Phosphatase Related to VHX*

  2004cited by this paper
• Locked nucleic acid modified DNA enzymes targeting early growth response-1 inhibit human vascular smooth muscle cell growth.

  2004cited by this paper
• The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation

  2004cited by this paper
• Local regulation of fat metabolism in peripheral nerves.

  2003cited by this paper
• Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10.

  2002cited by this paper
• Comparative analysis of Schwann cell lines as model systems for myelin gene transcription studies

  2002cited by this paper
• Deciphering peripheral nerve myelination by using Schwann cell expression profiling

  2002cited by this paper
• The Neuronal Adhesion Protein TAG-1 Is Expressed by Schwann Cells and Oligodendrocytes and Is Localized to the Juxtaparanodal Region of Myelinated Fibers

  2002cited by this paper
• Human Connexin 32, a gap junction protein altered in the X-linked form of Charcot-Marie-Tooth disease, is directly regulated by the transcription factor SOX10.

  2001cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• The transcription factor Sox10 is a key regulator of peripheral glial development.

  2001cited by this paper
• The glial transcription factor Sox10 binds to DNA both as monomer and dimer with different functional consequences.

  2000cited by this paper
• Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes.

  1999influential reference
• Myelin-Associated Glycoprotein Is a Myelin Signal that Modulates the Caliber of Myelinated Axons

  1998cited by this paper
• Differential regulation of the zinc finger genes Krox‐20 and Krox‐24 (Egr‐1) suggests antagonistic roles in Schwann cells

  1997cited by this paper
• The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation.

  1996cited by this paper
• The regulation of Krox-20 expression reveals important steps in the control of peripheral glial cell development.

  1996cited by this paper
• The Transcription Factors SCIP and Krox-20 Mark Distinct Stages and Cell Fates in Schwann Cell Differentiation

  1996cited by this paper
• Absence of the myelin-associated glycoprotein (MAG) and the neural cell adhesion molecule (N-CAM) interferes with the maintenance, but not with the formation of peripheral myelin

  1996cited by this paper
• DNA-binding specificity of NGFI-A and related zinc finger transcription factors

  1995cited by this paper
• Biochemical and Cellular Properties of Three Immortalized Schwann Cell Lines Expressing Different Levels of the Myelin‐Associated Glycoprotein

  1994influential reference
• Krox-20 controls myelination in the peripheral nervous system

  1994cited by this paper

• DUSP15 exhibits structural and dynamical signatures inconsistent with catalytic phosphatase activity.

  2026cites this paper
• The Atypical Dual Specificity Phosphatase DUSP15 Regulates Jak1-Mediated STAT3 Activation.

  2024cites this paper
• DUSP15 expression is reduced in the hippocampus of Myrf knock-out mice but attention and object recognition memory remain intact

  2023cites this paper
• Dissecting 16p11.2 hemi-deletion to study sex-specific striatal phenotypes of neurodevelopmental disorders

  2023cites this paper
• HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop

  2023cites this paper
• LEM Domain Containing 1 Acts as a Novel Oncogene and Therapeutic Target for Triple-Negative Breast Cancer

  2023cites this paper
• Electroceutical approach ameliorates intracellular PMP22 aggregation and promotes pro-myelinating pathways in a CMT1A in vitro model.

  2022cites this paper
• Dual-Specificity Phosphatase 15 (DUSP15) Modulates Notch Signaling by Enhancing the Stability of Notch Protein

  2021cites this paper
• Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder

  2021cites this paper
• Fibulin 5, a human Wharton's jelly‐derived mesenchymal stem cells‐secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin‐RAC1 signaling axis

  2020cites this paper
• Modelling the role of dual specificity phosphatases in Herceptin resistant breast cancer cell lines

  2019cites this paper
• Molecular Mechanisms Involved in Schwann Cell Plasticity

  2017influential citation