Development of novel self-assembled DS-PLGA hybrid nanoparticles for improving oral bioavailability of vincristine sulfate by P-gp inhibition.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Controlled Release

• Publication date

  2010-12-01

• Fields of study

  Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.jconrel.2010.08.010PMID 20727928
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pegylated Phospholipids-Based Self-Assembly with Water-Soluble Drugs

  2010cited by this paper
• Novel Mixed Polymeric Micelles for Enhancing Delivery of Anticancer Drug and Overcoming Multidrug Resistance in Tumor Cell Lines Simultaneously

  2010cited by this paper
• Beta-cyclodextrin-centered star-shaped amphiphilic polymers for doxorubicin delivery.

  2010cited by this paper
• Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo.

  2010cited by this paper
• PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery.

  2009cited by this paper
• Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

  2009cited by this paper
• Reversion of multidrug resistance by co-encapsulation of vincristine and verapamil in PLGA nanoparticles.

  2009cited by this paper
• The performance of docetaxel-loaded solid lipid nanoparticles targeted to hepatocellular carcinoma.

  2009cited by this paper
• Synthesis and antitumor activity of doxorubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles.

  2009cited by this paper
• Study progress of cell endocytosis

  2009cited by this paper
• Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform.

  2008cited by this paper
• PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: systematic study of particle size and drug entrapment efficiency.

  2008cited by this paper
• Molecular interactions, internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles.

  2008cited by this paper
• Comparative study of doxorubicin-loaded poly(lactide-co-glycolide) nanoparticles prepared by single and double emulsion methods.

  2007cited by this paper
• Screening of Lipid Carriers and Characterization of Drug-Polymer-Lipid Interactions for the Rational Design of Polymer-Lipid Hybrid Nanoparticles (PLN)

  2006cited by this paper
• Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer.

  2006cited by this paper
• A Mechanistic Study of Enhanced Doxorubicin Uptake and Retention in Multidrug Resistant Breast Cancer Cells Using a Polymer-Lipid Hybrid Nanoparticle System

  2006cited by this paper
• A New Polymer–Lipid Hybrid Nanoparticle System Increases Cytotoxicity of Doxorubicin Against Multidrug-Resistant Human Breast Cancer Cells

  2006cited by this paper
• Evaluation of ciprofloxacin-loaded Eudragit RS100 or RL100/PLGA nanoparticles.

  2006cited by this paper
• Role of clathrin- and caveolae-mediated endocytosis in gene transfer mediated by lipo- and polyplexes.

  2005cited by this paper
• Development of a nanoprecipitation method intended for the entrapment of hydrophilic drugs into nanoparticles.

  2005cited by this paper
• Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells.

  2005cited by this paper
• Hypoxia‐Induced Acidification Causes Mitoxantrone Resistance Not Mediated by Drug Transporters in Human Breast Cancer Cells

  2005cited by this paper
• Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention.

  2005cited by this paper
• Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin

  2005cited by this paper
• Indocyanine green-loaded biodegradable nanoparticles: preparation, physicochemical characterization and in vitro release.

  2004cited by this paper
• The Characteristics and Mechanisms of Uptake of PLGA Nanoparticles in Rabbit Conjunctival Epithelial Cell Layers

  2004cited by this paper
• Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis.

  2004cited by this paper
• Regulated portals of entry into the cell

  2003cited by this paper
• Biodegradable nanoparticles for drug and gene delivery to cells and tissue.

  2003cited by this paper
• Slow intracellular trafficking of catalase nanoparticles targeted to ICAM-1 protects endothelial cells from oxidative stress.

  2003cited by this paper
• Rapid endo‐lysosomal escape of poly(DL‐lactide‐coglycolide) nanoparticles: implications for drug and gene delivery

  2002cited by this paper
• Combination chemotherapy and photodynamic therapy of targetable N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin/mesochlorin e(6)-OV-TL 16 antibody immunoconjugates.

  2001cited by this paper
• Antitumor activity of N-(2-hydroxypropyl) methacrylamide copolymer-Mesochlorine e6 and adriamycin conjugates in combination treatments.

  2000cited by this paper
• Oral chemotherapy: rationale and future directions.

  1998cited by this paper
• Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action.

  1997cited by this paper
• Biodegradable submicron carriers for peptide drugs : Preparation of DL-lactide/glycolide copolymer(PLGA)nanospheres with nafarelin acetate by a novel emulsion-phase separation method in an oil system.

  1995cited by this paper
• [Antimicrotubule agents].

  1993cited by this paper
• Modulation of doxorubicin resistance in multidrug‐resistant cells by liposomes

  1993cited by this paper
• Molecular interactions.

  1978cited by this paper

• Design and Optimization of a Model Bcs Class II Drug-Loaded Glyceryl Monostearate Nanoparticles: Antidiabetic Efficacy and Teratogenic Safety in Zebrafish

  2025cites this paper
• Formulation and Characterisation of Herbal Ethosomal Gel of Luliconazole and Clove Oil for Modified Drug Diffusion to the Skin

  2025cites this paper
• Lipid-Polymer Hybrid Nanoparticles as a Smart Drug Delivery System for Peptide/Protein Delivery

  2025cites this paper
• Co-delivery of doxorubicin and piperine using niosomes exhibited enhanced cytotoxic and inhibitory effect on cancer stem cell markers in breast cancer cells

  2025cites this paper
• Platelet-inspired nanomedicine targeting activated neutrophils to alleviate ulcerative colitis by free radicals scavenging and controlled neutrophil swarming

  2024cites this paper
• Vincristine in Cancer Therapy: Mechanisms, Efficacy, and Future Perspectives.

  2024cites this paper
• A validated spectrophotometric analysis for simultaneous estimation of vincristine sulfate and bovine serum albumin in pure preparations using Vierordt’s method

  2024influential citation
• Formulation and Evaluation of Herbal Ethosomal Cream of Passiflora foetida Linn. for the Treatment of Psoriasis

  2024cites this paper
• Exploring the Therapeutic Potential of Anticancer Heterocyclic Compounds: Role in Nanoscale Pharmacotherapy.

  2023cites this paper
• Formulation of chitosan based lipid polymer hybrid nanocarrier system for oral delivery of tamoxifen citrate: Toxicological and hemocompatibility evaluation

  2023cites this paper
• Topical Delivery of Methoxsalen Co-loaded Curcumin Using Hybrid Nanocarrier-Based Polymeric Hydrogel for Synergistic Therapy in the Treatment of Psoriasis

  2023cites this paper
• Enhanced anti-tumor activity of transferrin/folate dual-targeting magnetic nanoparticles using chemo-thermo therapy on retinoblastoma cancer cells Y79

  2023cites this paper
• Reactive Oxygen Species-Responsive Nanocarrier Ameliorates Murine Colitis by Intervening Colonic Innate and Adaptive Immune Responses.

  2023cites this paper
• Organic Nanodelivery Systems as a New Platform in the Management of Breast Cancer: A Comprehensive Review from Preclinical to Clinical Studies

  2023cites this paper
• Vincristine-based nanoformulations: a preclinical and clinical studies overview

  2023influential citation
• DNA self-assembly nanoflower reverse P-glycoprotein mediated drug resistance in chronic myelogenous leukemia therapy

  2023cites this paper
• Self-Assembled Lipid Polymer Hybrid Nanoparticles Using Combinational Drugs for Migraine Via Intranasal Route

  2022cites this paper
• All-in-one theranostic nano-platform based on polymer nanoparticles for BRET/FRET-initiated bioluminescence imaging and synergistically anti-inflammatory therapy for ulcerative colitis

  2022cites this paper
• Nanocarrier-based co-delivery approaches of chemotherapeutics with natural P-glycoprotein inhibitors in the improvement of multidrug resistance cancer therapy

  2022cites this paper
• Melatonin loaded hybrid nanomedicine: DoE approach, optimization and in vitro study on diabetic retinopathy model.

  2022cites this paper
• Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer

  2022cites this paper
• Responsive role of nanomedicine in the tumor microenvironment and cancer drug resistance.

  2022cites this paper
• Improvised strategy of ethanolic nanovesicular gel of phospholipon 90G for transdermal delivery of luliconazole to mitigate fungal diseases

  2021cites this paper
• Lipopolysaccharide Nanosystems for the Enhancement of Oral Bioavailability

  2021cites this paper
• Fabrication strategies and supramolecular interactions of polymer-lipid complex nanoparticles as oral delivery systems

  2021cites this paper
• Stem cells and growth factors-based delivery approaches for chronic wound repair and regeneration: A promise to heal from within.

  2021cites this paper
• Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene therapy

  2021cites this paper
• PLGA Nanoparticles in Drug Delivery

  2021cites this paper
• Comparative Evaluation of In Vitro Drug Release Methods Employed for Nanoparticle Drug Release Studies

  2021cites this paper
• Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer.

  2021cites this paper
• Preparation of Functional Vincristine Liposomes for Treatment of Invasive Breast Cancer

  2021cites this paper
• PEGylated PLA-Phospholipon 90G complex hybrid nanoparticles loaded with etoricoxib for effective treatment pain relief potential

  2020cites this paper
• Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation

  2020cites this paper
• Nanomaterials for oral drug administration

  2020cites this paper
• Nanophytomedicine: An Effective Way for Improving Drug Delivery and Bioavailability of Herbal Medicines

  2020cites this paper
• Mitotic Poisons in Research and Medicine

  2020cites this paper
• A6 peptide-tagged, ultra-small and reduction-sensitive polymersomal vincristine sulfate as a smart and specific treatment for CD44+ acute myeloid leukemia.

  2020cites this paper
• Polymeric Nanoscale Drug Carriers Mediate the Delivery of Methotrexate for Developing Therapeutic Interventions Against Cancer and Rheumatoid Arthritis

  2020cites this paper
• Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

  2020cites this paper
• Nanomaterials as potential transporters of HDAC inhibitors

  2020cites this paper
• Herbal ethosomal gel containing luliconazole for productive relevance in the field of biomedicine

  2020influential citation
• Polymer-Lipid Hybrid Systems: Scope of Intravenous-To-Oral Switch in Cancer Chemotherapy

  2020cites this paper
• A doxorubicin and vincristine drug release system based on magnetic PLGA microspheres prepared by coaxial electrospray

  2019cites this paper
• CELL CARRIERS AS SYSTEMS OF DELIVERY OF ANTITUMOR DRUGS (REVIEW)

  2019cites this paper
• PEG-PLGA- hybrid nanoparticles loaded with etoricoxib – phospholipid complex for effective treatment of inflammation in rat model

  2019influential citation
• Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model

  2019cites this paper
• КЛЕТОЧНЫЕ НОСИТЕЛИ КАК СИСТЕМЫ ДОСТАВКИ ПРОТИВООПУХОЛЕВЫХ ЛЕКАРСТВЕННЫХ СРЕДСТВ (ОБЗОР)

  2019cites this paper
• Lipid-polymer hybrid nanoparticles: Synthesis strategies and biomedical applications.

  2019cites this paper
• An update on polymer-lipid hybrid systems for improving oral drug delivery

  2019cites this paper
• A PepT1 mediated medicinal nano-system for targeted delivery of cyclosporine A to alleviate acute severe ulcerative colitis.

  2019cites this paper
• Flurbiprofen-loaded ethanolic liposome particles for biomedical applications.

  2019cites this paper
• Novel Drug Delivery Systems for Phytoconstituents

  2019cites this paper
• IN-VIVO ANTI-TUMOR EFFECT OF 5-FLUOROURACIL LOADED CHITOSAN- SODIUM DEOXYCHOLATE NANOPARTICLES

  2019cites this paper
• On Demand Delivery of Methotrexate from Self-Assembled Nanoconstructs for Treatment of Rheumatoid Arthritis

  2019cites this paper
• Micronization of vincristine extracted from Catharanthus roseus by expansion of supercritical fluid solution

  2019cites this paper
• Hybrid nanocarriers based on PLGA-vegetable oil: A novel approach for high lipophilic drug delivery

  2018cites this paper
• How can nanotechnology help the fight against breast cancer?

  2018cites this paper
• Lipid-polymer hybrid nanocarrier-mediated cancer therapeutics: current status and future directions.

  2018cites this paper
• Chapter 4 Hybrid Nano-carriers for Potential Drug Delivery

  2018influential citation
• Comparison of hyaluronic acid-based micelles and polyethylene glycol-based micelles on reversal of multidrug resistance and enhanced anticancer efficacy in vitro and in vivo

  2018cites this paper
• Bioadhesive Chitosan-Coated Cationic Nanoliposomes With Improved Insulin Encapsulation and Prolonged Oral Hypoglycemic Effect in Diabetic Mice.

  2018cites this paper
• Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead.

  2018cites this paper
• Chitosan-functionalized lipid-polymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipid-lowering effect in NAFLD

  2018cites this paper
• Nanosized Drug Carriers for Oral Delivery of Anticancer Compounds and the Importance of the Chromatographic Techniques

  2017cites this paper
• Guggulosomes: A herbal approach for enhanced topical delivery of phenylbutazone

  2017cites this paper
• Lipid-polymer hybrid nanoparticles: Development & statistical optimization of norfloxacin for topical drug delivery system

  2017cites this paper
• Hybrid nanoparticles for the topical delivery of norfloxacin for the effective treatment of bacterial infection produced after burn

  2017cites this paper
• Enhancing the oral bioavailability of biochanin A by encapsulation in mixed micelles containing Pluronic F127 and Plasdone S630

  2017cites this paper
• Hyaluronic acid-coated cationic nanostructured lipid carriers for oral vincristine sulfate delivery

  2017cites this paper
• Biodegradable Self-Assembled Micelles Based on MPEG-PTMC Copolymers: An Ideal Drug Delivery System for Vincristine.

  2017cites this paper
• Targeted Therapeutic Nanoparticles: An Immense Promise to Fight against Cancer

  2017cites this paper
• Overview of Methods of Making Polyester Nano- and Microparticulate Systems for Drug Delivery

  2017cites this paper
• Systems for the delivery of chemotherapeutic drugs, new approaches and perspective

  2017cites this paper
• Drug-Loaded Polymeric Nanoparticles for Cancer Stem Cell Targeting

  2017cites this paper
• Hybrid Nano-carriers for Potential Drug Delivery

  2017cites this paper
• Wheat germ agglutinin modification of lipid–polymer hybrid nanoparticles: enhanced cellular uptake and bioadhesion

  2016cites this paper
• Targeted delivery of nano-PTX to the brain tumor-associated macrophages

  2016cites this paper
• Lysozyme-loaded lipid-polymer hybrid nanoparticles: preparation, characterization and colloidal stability evaluation

  2016cites this paper
• In Vitro and Ex Vivo Evaluations of Lipid Anti-Cancer Nanoformulations: Insights and Assessment of Bioavailability Enhancement

  2016cites this paper
• P-gp Inhibition-Based Strategies for Modulating Pharmacokinetics of Anticancer Drugs: An Update.

  2016cites this paper
• Synergistic and complete reversal of the multidrug resistance of mitoxantrone hydrochloride by three-in-one multifunctional lipid-sodium glycocholate nanocarriers based on simultaneous BCRP and Bcl-2 inhibition

  2016cites this paper
• Lipid polymer hybrid as emerging tool in nanocarriers for oral drug delivery

  2016cites this paper
• Nanostructured lipid–carrageenan hybrid carriers (NLCCs) for controlled delivery of mitoxantrone hydrochloride to enhance anticancer activity bypassing the BCRP-mediated efflux

  2016cites this paper
• The ligand (s) anchored lipobrid nanoconstruct mediated delivery of methotrexate: an effective approach in breast cancer therapeutics.

  2016cites this paper
• A novel approach in mucoadhesive drug delivery system to improve zidovudine intestinal permeability

  2016cites this paper
• Preparation and cellular targeting study of VEGF-conjugated PLGA nanoparticles

  2015influential citation
• Curcumin-Loaded Lipid Cubic Liquid Crystalline Nanoparticles: Preparation, Optimization, Physicochemical Properties and Oral Absorption.

  2015cites this paper
• Engineering the lipid layer of lipid-PLGA hybrid nanoparticles for enhanced in vitro cellular uptake and improved stability.

  2015cites this paper
• Tumor-targeted co-delivery of mitomycin C and 10-hydroxycamptothecin via micellar nanocarriers for enhanced anticancer efficacy

  2015cites this paper
• Fabrication, Characterization and Biological Fate of Phytochemical Delivery System

  2015influential citation
• Engineering Biomaterial-Drug Conjugates for Local and Sustained Chemotherapeutic Delivery.

  2015cites this paper
• Nanomicelles based on X-shaped four-armed peglyated distearylglycerol as long circulating system for doxorubicin delivery.

  2015cites this paper
• Drug Delivery Systems and Combination Therapy by Using Vinca Alkaloids

  2015cites this paper
• Hybrid poly(lactic-co-glycolic acid) nanoparticles: design and delivery prospectives.

  2015cites this paper
• Development of docetaxel nanocapsules for improving in vitro cytotoxicity and cellular uptake in MCF-7 cells

  2015cites this paper
• Recent trends in preparation of poly(lactide- co -glycolide) nanoparticles by mixing polymeric organic solution with antisolvent

  2015cites this paper
• Direct Fluorescent Detection of a Polymethoxyflavone in Cell Culture and Mouse Tissue.

  2015cites this paper
• Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design

  2015cites this paper
• The role of lipid-based nano delivery systems on oral bioavailability enhancement of fenofibrate, a BCS II drug: comparison with fast-release formulations

  2014cites this paper
• Novel methotrexate prodrug-targeted drug delivery system based on PEG-lipid-PLA hybrid nanoparticles for enhanced anticancer efficacy and reduced toxicity of mitomycin C.

  2014cites this paper