Down-regulation of Micro-RNA-1 (miR-1) in Lung Cancer

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Journal of Biological Chemistry

• Publication date

  2008-11-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1074/jbc.M804788200PMID 18818206PMCID PMC2586284
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Safety and anti-tumor activity of sorafenib (Nexavar®) in combination with other anti-cancer agents: a review of clinical trials

  2008cited by this paper
• Elevated Levels of Oncogenic Protein Kinase Pim-1 Induce the p53 Pathway in Cultured Cells and Correlate with Increased Mdm2 in Mantle Cell Lymphoma*

  2008cited by this paper
• Small non-coding RNAs in animal development

  2008cited by this paper
• Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

  2008cited by this paper
• MicroRNA function in neuronal development, plasticity and disease.

  2008cited by this paper
• Normalization of microRNA expression levels in quantitative RT-PCR assays: identification of suitable reference RNA targets in normal and cancerous human solid tissues.

  2008cited by this paper
• MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN.

  2008cited by this paper
• Methylation mediated silencing of MicroRNA-1 gene and its role in hepatocellular carcinogenesis.

  2008cited by this paper
• Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

  2008cited by this paper
• In situ detection of precursor and mature microRNAs in paraffin embedded, formalin fixed tissues and cell preparations.

  2008cited by this paper
• Treatment of PC12 Cells with Nerve Growth Factor Induces Proteasomal Degradation of T-cadherin That Requires Tyrosine Phosphorylation of Its Cadherin Domain*

  2007cited by this paper
• Impaired microRNA processing enhances cellular transformation and tumorigenesis

  2007cited by this paper
• MicroRNA-155 is induced during the macrophage inflammatory response

  2007cited by this paper
• Mechanisms of microRNA‐mediated gene regulation

  2007cited by this paper
• microRNAs in vertebrate physiology and human disease.

  2007cited by this paper
• MicroRNA genes are frequently located near mouse cancer susceptibility loci

  2007cited by this paper
• Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation

  2007cited by this paper
• FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo.

  2007cited by this paper
• Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.

  2007cited by this paper
• MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy.

  2007cited by this paper
• The guardian's little helper: microRNAs in the p53 tumor suppressor network.

  2007cited by this paper
• MicroRNAs and immunity: tiny players in a big field.

  2007cited by this paper
• Structural insights into the degradation of Mcl-1 induced by BH3 domains

  2007cited by this paper
• Cancer Statistics, 2007

  2007cited by this paper
• RT-PCR-based analysis of microRNA (miR-1 and -124) expression in mouse CNS.

  2007cited by this paper
• MicroRNAs and their regulatory roles in animals and plants

  2007cited by this paper
• The evolution of animal microRNA function.

  2007cited by this paper
• The Human Angiotensin II Type 1 Receptor +1166 A/C Polymorphism Attenuates MicroRNA-155 Binding*

  2007cited by this paper
• microRNAs put their signatures on the heart.

  2007cited by this paper
• MicroRNAs in cell proliferation, cell death, and tumorigenesis.

  2007cited by this paper
• MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

  2007cited by this paper
• Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies

  2007cited by this paper
• FOXP1: a potential therapeutic target in cancer

  2007cited by this paper
• The Met pathway: master switch and drug target in cancer progression

  2006cited by this paper
• Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.

  2006cited by this paper
• Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas

  2006cited by this paper
• Foxp1 is an essential transcriptional regulator of B cell development

  2006cited by this paper
• Unique microRNA molecular profiles in lung cancer diagnosis and prognosis.

  2006cited by this paper
• C/EBPa mutations in lung cancer

  2006cited by this paper
• Interrelated Roles for Mcl-1 and BIM in Regulation of TRAIL-mediated Mitochondrial Apoptosis*

  2006cited by this paper
• C/EBP alpha mutations in lung cancer.

  2006cited by this paper
• MicroRNAs and chromosomal abnormalities in cancer cells

  2006cited by this paper
• C/EBPalpha: a tumour suppressor in multiple tissues?

  2006cited by this paper
• C/EBPα: A tumour suppressor in multiple tissues?

  2006cited by this paper
• MicroRNA signatures in human cancers

  2006cited by this paper
• Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.

  2006cited by this paper
• A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

  2006cited by this paper
• Oncomirs — microRNAs with a role in cancer

  2006cited by this paper
• Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines.

  2006cited by this paper
• The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation

  2006cited by this paper
• Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype.

  2006cited by this paper
• MicroRNA-cancer connection: the beginning of a new tale.

  2006cited by this paper
• RAS is regulated by the let-7 microRNA family.

  2005cited by this paper
• Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis

  2005cited by this paper
• MicroRNA biogenesis: coordinated cropping and dicing

  2005cited by this paper
• Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth.

  2005cited by this paper
• State of the Art in Therapy for Non-Small Cell Lung Cancer

  2005cited by this paper
• 5-Aza-Deoxycytidine Induces Selective Degradation of DNA Methyltransferase 1 by a Proteasomal Pathway That Requires the KEN Box, Bromo-Adjacent Homology Domain, and Nuclear Localization Signal

  2005cited by this paper
• Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells

  2005cited by this paper
• Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.

  2005cited by this paper
• Targeting apoptosis pathways in cancer therapy.

  2004cited by this paper
• Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer.

  2004cited by this paper
• Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival

  2004cited by this paper
• Molecular genetics of lung cancer.

  2003cited by this paper
• Using TESS to Predict Transcription Factor Binding Sites in DNA Sequence

  2003cited by this paper
• Prediction of mammalian microRNA targets.

  2003cited by this paper
• Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma.

  2003cited by this paper
• C/EBP transcription factors in the lung epithelium.

  2003cited by this paper
• Molecular genetics of lung cancer.

  1988cited by this paper

• Cigarette smoke induces angiogenic activation in the cancer field through dysregulation of an endothelial microRNA

  2025cites this paper
• MiR‐1 Is Regulated by Hydrogen Peroxide via MAPK and Limits Cell Migration and Invasion

  2025cites this paper
• Non-coding RNAs as therapeutic targets in cancer and its clinical application

  2024cites this paper
• Circulating miR-206 and miR-1246 as Markers in the Early Diagnosis of Lung Cancer in Patients with Chronic Obstructive Pulmonary Disease

  2023cites this paper
• Cell cycle associated miRNAs as target and therapeutics in lung cancer treatment

  2022cites this paper
• Gastrointestinal disorder biomarkers.

  2022cites this paper
• Relationship between the microRNAs and PI3K/AKT/mTOR axis: Focus on non-small cell lung cancer.

  2022cites this paper
• Expression of miRNA1, miRNA133, miRNA191, and miRNA24, as Good Biomarkers, in Non-Small Cell Lung Cancer Using Real-Time PCR Method

  2022cites this paper
• The Risks of miRNA Therapeutics: In a Drug Target Perspective

  2021cites this paper
• Expression of lncRNA-HOTAIR in the serum of patients with lymph node metastasis of papillary thyroid carcinoma and its impact

  2020cites this paper
• Integrated molecular docking, 3D QSAR and molecular dynamics simulation studies on indole derivatives for designing new Pim-1 inhibitors

  2020cites this paper
• Upregulation of microRNA-1 inhibits proliferation and metastasis of breast cancer

  2020cites this paper
• Dissecting miRNA facilitated physiology and function in human breast cancer for therapeutic intervention.

  2020cites this paper
• MicroRNAs in the anticancer effects of celecoxib: A systematic review.

  2020cites this paper
• Recent trends in targeting miRNAs for cancer therapy

  2020cites this paper
• miR-195-5p exerts tumor-suppressive functions in human lung cancer cells through targeting TrxR2.

  2020cites this paper
• Dual Effects of Non-Coding RNAs (ncRNAs) in Cancer Stem Cell Biology

  2020cites this paper
• MicroRNA-92a promotes non-small cell lung cancer cell growth by targeting tumor suppressor gene FBXW7

  2020cites this paper
• MicroRNAs and Long Non-coding RNAs in c-Met-Regulated Cancers

  2020cites this paper
• Microarray data analysis on gene and miRNA expression to identify biomarkers in non-small cell lung cancer

  2020cites this paper
• microRNA-1 Regulates NCC Migration and Differentiation by Targeting sec63

  2019cites this paper
• miR-1 reverses multidrug resistance in gastric cancer cells via downregulation of sorcin through promoting the accumulation of intracellular drugs and apoptosis of cells

  2019cites this paper
• MiR-1-5p is down-regulated in gallbladder carcinoma and suppresses cell proliferation, migration and invasion by targeting Notch2.

  2019cites this paper
• MicroRNA in lung cancer: role, mechanisms, pathways and therapeutic relevance.

  2019cites this paper
• miR‐193b represses influenza A virus infection by inhibiting Wnt/β‐catenin signalling

  2019cites this paper
• Contributory role of microRNAs in anti‐cancer effects of small molecule inhibitor of telomerase (BIBR1532) on acute promyelocytic leukemia cell line

  2019cites this paper
• Phytochemicals as Epigenetic Modifiers for Cancer Management With Special Reference to Lung Cancer

  2019cites this paper
• Emerging roles of microRNAs as a regulator in the progression of lung cancer and their implications in its diagnosis and therapy

  2019cites this paper
• miR-512-5p suppresses proliferation, migration and invasion, and induces apoptosis in non-small cell lung cancer cells by targeting ETS1

  2019cites this paper
• EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer

  2019cites this paper
• MicroRNA-1 suppresses glioblastoma in preclinical models by targeting fibronectin.

  2019cites this paper
• Circulating MiR-10b, MiR-1 and MiR-30a Expression Profiles in Lung Cancer: Possible Correlation with Clinico-pathologic Characteristics and Lung Cancer Detection.

  2019cites this paper
• MiR-1 Suppresses Proliferation of Osteosarcoma Cells by Up-regulating p21 via PAX3

  2018cites this paper
• Star-Graft Quarterpolymer-Based Polymersomes as Nanocarriers for Co-Delivery of Hydrophilic/Hydrophobic Chemotherapeutic Agents

  2018cites this paper
• MicroRNA‐1 overexpression increases chemosensitivity of non‐small cell lung cancer cells by inhibiting autophagy related 3‐mediated autophagy

  2018cites this paper
• The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer

  2018cites this paper
• Stable miRNA overexpression in human CAP cells: Engineering alternative production systems for advanced manufacturing of biologics using miR‐136 and miR‐3074

  2018cites this paper
• Identification and verification of differentially expressed microRNAs and their target genes for the diagnosis of esophageal cancer

  2018cites this paper
• miR-1 inhibits the progression of colon cancer by regulating the expression of vascular endothelial growth factor

  2018cites this paper
• miR‐1‐3p and miR‐206 sensitizes HGF‐induced gefitinib‐resistant human lung cancer cells through inhibition of c‐Met signalling and EMT

  2018cites this paper
• The reciprocal link between EVI1 and miRNAs in human malignancies.

  2018cites this paper
• Epigenetics and MicroRNAs in Cancer

  2018cites this paper
• Serum MicroRNA Signature Predicts Response to High-Dose Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer.

  2018cites this paper
• Updates on the hepatocyte growth factor/c-Met axis in hepatocellular carcinoma and its therapeutic implications

  2018cites this paper
• Aberrant expression of microRNAs and the miR‐1/MET pathway in canine hepatocellular carcinoma

  2018cites this paper
• The Potential Contribution of microRNAs in Anti-cancer Effects of Aurora Kinase Inhibitor (AZD1152-HQPA)

  2018cites this paper
• The long non-coding RNA HOTAIR promotes thyroid cancer cell growth, invasion and migration through the miR-1-CCND2 axis.

  2017cites this paper
• Elucidating mechanisms of sunitinib resistance in renal cancer: an integrated pathological-molecular analysis

  2017cites this paper
• Systematic analysis reveals tumor-enhancing and -suppressing microRNAs in Drosophila epithelial tumors

  2017cites this paper
• Using miR-10b, miR-1 and miR-30a expression profiles of bronchoalveolar lavage and sputum for early detection of non-small cell lung cancer

  2017cites this paper
• Regulation of microRNA-1 (miR-1) expression in human cancer.

  2017cites this paper
• Repression of the protein kinase PIM3 by an mTORC1-regulated microRNA

  2017cites this paper
• MicroRNA-1 inhibits ovarian cancer cell proliferation and migration through c-Met pathway.

  2017cites this paper
• miRNAs as Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer: Current Perspectives

  2017cites this paper
• Role of miR-1 expression in clear cell renal cell carcinoma (ccRCC): A bioinformatics study based on GEO, ArrayExpress microarrays and TCGA database.

  2017cites this paper
• MotomiRs: miRNAs in Motor Neuron Function and Disease

  2017cites this paper
• A new insight on reciprocal relationship between microRNA expression and epigenetic modifications in human lung cancer

  2017cites this paper
• A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients With Ulcerative Colitis-Associated Colorectal Cancer.

  2017cites this paper
• MicroRNAs in DNA Damage Response, Carcinogenesis, and Chemoresistance.

  2017cites this paper
• MiR-1 suppresses tumor cell proliferation in colorectal cancer by inhibition of Smad3-mediated tumor glycolysis

  2017cites this paper
• Tumor suppressor miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes

  2017cites this paper
• ADAM9 enhances CDCP1 by inhibiting miR-1 through EGFR signaling activation in lung cancer metastasis

  2017cites this paper
• Bioinformatics analyses of the differences between lung adenocarcinoma and squamous cell carcinoma using The Cancer Genome Atlas expression data

  2017cites this paper
• MicroRNA-1 and MicroRNA-21 Individually Regulate Cellular Growth of Non-malignant and Malignant Renal Cells.

  2017cites this paper
• Toxicity study of ochratoxin A using HEK293 and HepG2 cell lines based on microRNA profiling

  2017cites this paper
• The Enigma of miRNA Regulation in Cancer

  2017cites this paper
• The PI3K/mTOR dual inhibitor BEZ235 suppresses proliferation and migration and reverses multidrug resistance in acute myeloid leukemia

  2017cites this paper
• MicroRNA-1 upregulation promotes myocardiocyte proliferation and suppresses apoptosis during heart development.

  2017cites this paper
• Fish miR-146a promotes Singapore grouper iridovirus infection by regulating cell apoptosis and NF-κB activation.

  2017cites this paper
• MiR-1-3p Suppresses the Proliferation, Invasion and Migration of Bladder Cancer Cells by Up-Regulating SFRP1 Expression

  2017cites this paper
• A novel computational model based on super-disease and miRNA for potential miRNA-disease association prediction.

  2017cites this paper
• miR‐1 suppresses the proliferation and promotes the apoptosis of esophageal carcinoma cells by targeting Src

  2017cites this paper
• Thrombospondin‐1 and microRNA‐1 expression in response to multiwalled carbon nanotubes in alveolar epithelial cells

  2017cites this paper
• MicroRNA-29c functions as a tumor suppressor by targeting VEGFA in lung adenocarcinoma

  2017cites this paper
• MicroRNA-1 inhibits tumorigenicity of esophageal squamous cell carcinoma and enhances sensitivity to gefitinib

  2017cites this paper
• Downregulation of miR-1 enhances tumorigenicity and invasiveness in oral squamous cell carcinomas.

  2017cites this paper
• Genome-wide analysis of aberrantly expressed microRNAs in bronchoalveolar lavage fluid from patients with silicosis

  2016cites this paper
• Regulation of the MET oncogene: molecular mechanisms.

  2016cites this paper
• Susceptibility of microRNAs 145, 143 and 133b to epigenetic regulation in colorectal cancer cell lines; prediction and functional analysis of putative targets to associated microRNAs

  2016cites this paper
• A selective screening platform reveals unique global expression patterns of microRNAs in a cohort of human soft-tissue sarcomas

  2016cites this paper
• miR-1 association with cell proliferation inhibition and apoptosis in vestibular schwannoma by targeting VEGFA.

  2016cites this paper
• miR-1 Inhibits Cell Growth, Migration, and Invasion by Targeting VEGFA in Osteosarcoma Cells

  2016cites this paper
• The tumor‐suppressive function of miR‐1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma

  2016cites this paper
• High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2

  2016cites this paper
• Regulation of class IIa HDAC activities: it is not only matter of subcellular localization.

  2016cites this paper
• Transcription factor CCAAT/enhancer binding protein alpha up-regulates microRNA let-7a-1 in lung cancer cells by direct binding

  2016cites this paper
• The Tumor Suppressor MicroRNA-1 Exhibits Restricted Inhibition of Proliferation of Ovarian Cancer Cells.

  2016cites this paper
• MicroRNA-1 properties in cancer regulatory networks and tumor biology.

  2016cites this paper
• Integrated analysis of the miRNA, gene and pathway regulatory network in gastric cancer.

  2016cites this paper
• Green tea polyphenol EGCG suppresses osteosarcoma cell growth through upregulating miR-1

  2016cites this paper
• MicroRNA-375 Functions as a Tumor-Suppressor Gene in Gastric Cancer by Targeting Recepteur d’Origine Nantais

  2016cites this paper
• MicroRNA-206 inhibits the viability and migration of human lung adenocarcinoma cells partly by targeting MET.

  2016cites this paper
• A serum microRNA signature as a prognostic factor for patients with advanced NSCLC and its association with tissue microRNA expression profiles

  2016cites this paper
• Insights into roles of the miR-1, -133 and -206 family in gastric cancer (Review).

  2016cites this paper
• miRNAs Signature in Head and Neck Squamous Cell Carcinoma Metastasis: A Literature Review

  2016cites this paper
• MicroRNA-206 attenuates the growth and angiogenesis in non-small cell lung cancer cells by blocking the 14-3-3ζ/STAT3/HIF-1α/VEGF signaling

  2016cites this paper
• Endothelial and circulating C19MC microRNAs are biomarkers of infantile hemangioma.

  2016cites this paper
• MicroRNAs associated with small bowel neuroendocrine tumours and their metastases.

  2016cites this paper
• Hsa-miR-329 exerts tumor suppressor function through down-regulation of MET in non-small cell lung cancer

  2016cites this paper
• Association of Nuclear PIM1 Expression with Lymph Node Metastasis and Poor Prognosis in Patients with Lung Adenocarcinoma and Squamous Cell Carcinoma

  2016cites this paper