Extracellular matrix roles during cardiac repair.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Life Science

• Publication date

  2010-09-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.lfs.2010.07.010PMID 20670633PMCID PMC2946433
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease.

  2010cited by this paper
• Tenascin-C may aggravate left ventricular remodeling and function after myocardial infarction in mice.

  2010cited by this paper
• The dynamics of fibroblast–myocyte–capillary interactions in the heart

  2010cited by this paper
• Non-fibrillar collagens: key mediators of post-infarction cardiac remodeling?

  2010cited by this paper
• Translational lessons from scarless healing of cutaneous wounds and regenerative repair of the myocardium.

  2010cited by this paper
• In vivo matrix metalloproteinase-7 substrates identified in the left ventricle post-myocardial infarction using proteomics.

  2010cited by this paper
• Proteomic analysis identifies in vivo candidate matrix metalloproteinase‐9 substrates in the left ventricle post‐myocardial infarction

  2010cited by this paper
• Cardiac extracellular matrix remodeling: fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC).

  2010cited by this paper
• Monocytes in heart failure: relationship to a deteriorating immune overreaction or a desperate attempt for tissue repair?

  2010cited by this paper
• Matricryptic sites control tissue injury responses in the cardiovascular system: relationships to pattern recognition receptor regulated events.

  2010cited by this paper
• Chemokines and cardiac fibrosis.

  2009cited by this paper
• The pathology of chronic obstructive pulmonary disease.

  2009cited by this paper
• Mouse strain determines the outcome of wound healing after myocardial infarction.

  2009cited by this paper
• MMP-9 Sheds the β2 Integrin Subunit (CD18) from Macrophages*S

  2009cited by this paper
• Transcriptional and posttranscriptional regulators of biglycan in cardiac fibroblasts

  2009cited by this paper
• Emerging concepts in cardiac matrix biology.

  2009cited by this paper
• Incremental prognostic values of serum tenascin-C levels with blood B-type natriuretic peptide testing at discharge in patients with dilated cardiomyopathy and decompensated heart failure.

  2009cited by this paper
• Inflammasomes: too big to miss.

  2009cited by this paper
• Acute coronary syndromes: morbidity, mortality, and pharmacoeconomic burden.

  2009cited by this paper
• Tenascins and their implications in diseases and tissue mechanics

  2009cited by this paper
• Pulmonary fibrosis: pathogenesis, etiology and regulation

  2009cited by this paper
• The Role of Interleukin-6 in the Formation of the Coronary Vasculature

  2009cited by this paper
• Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts.

  2009cited by this paper
• Activation and modulation of 72kDa matrix metalloproteinase-2 by peroxynitrite and glutathione.

  2009cited by this paper
• The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of fibrotic disorders

  2009cited by this paper
• Pressure Overload–Induced Alterations in Fibrillar Collagen Content and Myocardial Diastolic Function: Role of Secreted Protein Acidic and Rich in Cysteine (SPARC) in Post–Synthetic Procollagen Processing

  2009cited by this paper
• The basic helix-loop-helix transcription factor scleraxis regulates fibroblast collagen synthesis.

  2009cited by this paper
• The role of IL-1 in the pathogenesis of heart disease

  2009cited by this paper
• Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction

  2009cited by this paper
• Glycogen synthase kinase-3beta is activated by matrix metalloproteinase-2 mediated proteolysis in cardiomyoblasts.

  2009cited by this paper
• Cardiac fibroblasts: at the heart of myocardial remodeling.

  2009cited by this paper
• Activation of MMP-2 as a key event in oxidative stress injury to the heart.

  2009cited by this paper
• Transforming growth factor beta-induced endothelial-to-mesenchymal transition: a switch to cardiac fibrosis?

  2008cited by this paper
• The importance of proline residues in the structure, stability and susceptibility to proteolytic degradation of collagens

  2008cited by this paper
• Biglycan Is Required for Adaptive Remodeling After Myocardial Infarction

  2008cited by this paper
• Periostin is essential for cardiac healingafter acute myocardial infarction

  2008cited by this paper
• CD44 Is Critically Involved in Infarct Healing by Regulating the Inflammatory and Fibrotic Response1

  2008cited by this paper
• Cellular and molecular mechanisms of fibrosis

  2008cited by this paper
• Oxidative stress and left ventricular remodelling after myocardial infarction.

  2008cited by this paper
• Production of Type VI Collagen by Human Macrophages: A New Dimension in Macrophage Functional Heterogeneity1 2

  2008cited by this paper
• Post-infarct remodelling: contribution of wound healing and inflammation

  2008cited by this paper
• Perlecan is critical for heart stability.

  2008cited by this paper
• Fragments of extracellular matrix as mediators of inflammation.

  2008cited by this paper
• Human Cord Blood Mononuclear Cells Decrease Cytokines and Inflammatory Cells in Acute Myocardial Infarction

  2008cited by this paper
• New insights into form and function of fibronectin splice variants

  2008cited by this paper
• Toll-Like Receptor-4 Modulates Survival by Induction of Left Ventricular Remodeling after Myocardial Infarction in Mice1

  2008cited by this paper
• Transforming growth factor beta inhibition increases mortality and left ventricular dilatation after myocardial infarction

  2008cited by this paper
• The immune system and cardiac repair.

  2008cited by this paper
• Bone marrow‐derived myofibroblasts contribute functionally to scar formation after myocardial infarction

  2008cited by this paper
• Macrophage roles following myocardial infarction.

  2008cited by this paper
• Neutrophil Elastase Cleaves Laminin-332 (Laminin-5) Generating Peptides That Are Chemotactic for Neutrophils*

  2008cited by this paper
• An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma

  2007cited by this paper
• The transcriptional coactivator and acetyltransferase p300 in fibroblast biology and fibrosis

  2007cited by this paper
• The role of the thrombospondins in healing myocardial infarcts.

  2007cited by this paper
• Survival pathways in hypertrophy and heart failure: The gp130-STAT3 axis

  2007cited by this paper
• Mechanism of TNFalpha-induced IL-1alpha, IL-1beta and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones.

  2007cited by this paper
• Human Collagen Krox Up-regulates Type I Collagen Expression in Normal and Scleroderma Fibroblasts through Interaction with Sp1 and Sp3 Transcription Factors*

  2007cited by this paper
• Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts : Effects of statins and thiazolidinediones

  2007cited by this paper
• Native and fragmented fibronectin oppositely modulate monocyte secretion of MMP‐9

  2007cited by this paper
• The myofibroblast: one function, multiple origins.

  2007cited by this paper
• The Biochemical, Biological, and Pathological Kaleidoscope of Cell Surface Substrates Processed by Matrix Metalloproteinases

  2007cited by this paper
• Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

  2007cited by this paper
• Novel strategies to delineate matrix metalloproteinase (MMP)-substrate relationships and identify targets to block MMP activity.

  2006cited by this paper
• Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice

  2006cited by this paper
• Bone marrow-derived cells do not contribute significantly to collagen I synthesis in a murine model of renal fibrosis.

  2006cited by this paper
• Fibroblast migration after myocardial infarction is regulated by transient SPARC expression

  2006cited by this paper
• Extracellular matrix remodeling in canine and mouse myocardial infarcts

  2006cited by this paper
• Cardiac myofibroblasts differentiated in 3D culture exhibit distinct changes in collagen I production, processing, and matrix deposition.

  2006cited by this paper
• Endostatin, the Proteolytic Fragment of Collagen XVIII, Induces Vasorelaxation

  2006cited by this paper
• Targeting the inflammatory response in healing myocardial infarcts.

  2006cited by this paper
• Increased inflammatory response and neovascularization in reperfused vs. non-reperfused murine myocardial infarction.

  2006cited by this paper
• Matrix Metalloproteinase-7 Affects Connexin-43 Levels, Electrical Conduction, and Survival After Myocardial Infarction

  2006cited by this paper
• The matrix component biglycan is proinflammatory and signals through Toll-like receptors 4 and 2 in macrophages.

  2005cited by this paper
• SPARC-thrombospondin-2-double-null Mice Exhibit Enhanced Cutaneous Wound Healing and Increased Fibrovascular Invasion of Subcutaneous Polyvinyl Alcohol Sponges

  2005cited by this paper
• A role for decorin in the remodeling of myocardial infarction.

  2005cited by this paper
• Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury.

  2005cited by this paper
• Structural and functional characterisation of cardiac fibroblasts.

  2005cited by this paper
• Perspective Article: Tissue repair, contraction, and the myofibroblast

  2005cited by this paper
• Critical Role of Endogenous Thrombospondin-1 in Preventing Expansion of Healing Myocardial Infarcts

  2005cited by this paper
• Hsp47 a novel collagen binding serpin chaperone, autoantigen and therapeutic target.

  2005cited by this paper
• The cardiac fibroblast: therapeutic target in myocardial remodeling and failure.

  2005cited by this paper
• A Highly Specific Inhibitor of Matrix Metalloproteinase-9 Rescues Laminin from Proteolysis and Neurons from Apoptosis in Transient Focal Cerebral Ischemia

  2005cited by this paper
• Peptides Derived from Human Decorin Leucine-rich Repeat 5 Inhibit Angiogenesis*

  2005cited by this paper
• Intracardiac fibroblasts, but not bone marrow derived cells, are the origin of myofibroblasts in myocardial infarct repair.

  2005cited by this paper
• Matrikines and matricryptins: Implications for cutaneous cancers and skin repair.

  2005cited by this paper
• Functional Sites in the Laminin Alpha Chains

  2005cited by this paper
• Structure and mechanics of healing myocardial infarcts.

  2005cited by this paper
• Inhibition of TGF-beta signaling exacerbates early cardiac dysfunction but prevents late remodeling after infarction.

  2004cited by this paper
• Role of proteases in the pathophysiology of cardiac disease

  2004cited by this paper
• Extracellular matrix signaling through growth factor receptors during wound healing

  2004cited by this paper
• Role of proteases in the pathophysiology of cardiac disease.

  2004cited by this paper
• Endothelin‐1 is an essential co‐factor for β2‐adrenergic receptor‐induced proliferation of human cardiac fibroblasts

  2004cited by this paper
• Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction.

  2004cited by this paper
• Inflammation and Ischemia: Macrophages Activated by Fibronectin Fragments Enhance the Survival of Injured Cardiac Myocytes

  2004cited by this paper
• Tumor necrosis factor alpha induces human atrial myofibroblast proliferation, invasion and MMP-9 secretion: inhibition by simvastatin.

  2004cited by this paper
• A Site on Laminin α5, AQARSAASKVKVSMKF, Induces Inflammatory Cell Production of Matrix Metalloproteinase-9 and Chemotaxis1

  2003cited by this paper
• Reduced Myocardial Ischemia-Reperfusion Injury in Toll-Like Receptor 4-Deficient Mice

  2003cited by this paper
• SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength.

  2003cited by this paper
• Effect of a Cleavage-Resistant Collagen Mutation on Left Ventricular Remodeling

  2003cited by this paper
• Myofibroblast and endothelial cell proliferation during murine myocardial infarct repair.

  2003cited by this paper

• A 3D Bioprinted dECM/CSCA/SA/NC Hybrid Scaffold for Myocardial Infarction Healing.

  2026cites this paper
• Exercise training ameliorates myocardial dysfunction through fibronectin mediated mechanotransduction in a swine model of ischemic heart disease.

  2025cites this paper
• Cardiotoxicity Beyond Cardiomyocytes-Focus on the Role of Cardiac Fibroblasts and Endothelial Cells.

  2025cites this paper
• Matrisome gene expression is altered during non-allometric heart growth in genetically enlarged Drosophila

  2024cites this paper
• 3D and 4D Printed Materials for Cardiac Transplantation: Advances in Biogenerative Engineering

  2024cites this paper
• Modified mRNA-Mediated CCN5 Gene Transfer Ameliorates Cardiac Dysfunction and Fibrosis without Adverse Structural Remodeling

  2024cites this paper
• Mending a broken heart by biomimetic 3D printed natural biomaterial-based cardiac patches: a review

  2023cites this paper
• Proton Transport Across Collagen Fibrils and Scaffolds: The Role of Hydroxyproline.

  2023cites this paper
• Cardiac function and ECM morphology are altered with high fat diets in Drosophila

  2023cites this paper
• ECM biomechanics in cardiac tissue decellularization.

  2022cites this paper
• Protein Alterations in Cardiac Ischemia/Reperfusion Revealed by Spatial-Omics

  2022cites this paper
• Role of Inflammatory Niche and Adult Cardiomyocyte Coculture on Differentiation, Matrix Synthesis, and Secretome Release by Human Bone Marrow Mesenchymal Stem Cells

  2022cites this paper
• Examining variation and temporal dynamics of extracellular matrix biomarkers following acute myocardial infarction.

  2022cites this paper
• Left Ventricular Remodeling after Myocardial Infarction: From Physiopathology to Treatment

  2022cites this paper
• Gelatin coating enhances therapeutic cell adhesion to the infarcted myocardium via ECM binding

  2022influential citation
• The role of the dystrophin glycoprotein complex in muscle cell mechanotransduction

  2022cites this paper
• 3D Bioprinted Cardiac Tissues and Devices for Tissue Maturation

  2021cites this paper
• Delivery of cardiovascular progenitors with biomimetic microcarriers reduces adverse ventricular remodeling in a rat model of chronic myocardial infarction.

  2021cites this paper
• Cell-adhesion Activities Responding to Nano-Dynamic Substrate

  2021cites this paper
• A dynamic microscale mid-throughput fibrosis model to investigate the effects of different ratios of cardiomyocytes and fibroblasts

  2021cites this paper
• Adult stem cell niches for tissue homeostasis

  2021cites this paper
• Deciphering the in vivo Dynamic Proteomics of Mesenchymal Stem Cells in Critical Limb Ischemia

  2021cites this paper
• A combined biomarker approach for characterising extracellular matrix profiles in acute myocardial infarction

  2021cites this paper
• Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice.

  2021cites this paper
• Bearing My Heart: The Role of Extracellular Matrix on Cardiac Development, Homeostasis, and Injury Response

  2021cites this paper
• Infarct in the Heart: What’s MMP-9 Got to Do with It?

  2021cites this paper
• Transient receptor potential channel TRPV4 mediates TGF-β1-induced differentiation of human ventricular fibroblasts.

  2020cites this paper
• Chronobiological Influence Over Cardiovascular Function: The Good, the Bad, and the Ugly.

  2020cites this paper
• Post-Myocardial Infarction Ventricular Remodeling Biomarkers—The Key Link between Pathophysiology and Clinic

  2020cites this paper
• Focus on fibroblasts : development, plasticity, and therapeutic challenges in the cardiac fibroblast lineage.

  2020cites this paper
• TRPV4 deletion protects heart from myocardial infarction-induced adverse remodeling via modulation of cardiac fibroblast differentiation

  2020cites this paper
• Promoting Cardiac Regeneration and Repair Using Acellular Biomaterials

  2020cites this paper
• Micromechanobiology: Focusing on the Cardiac Cell-Substrate Interface.

  2020cites this paper
• Engineering hiPSC cardiomyocyte in vitro model systems for functional and structural assessment.

  2019cites this paper
• Characterisation of a Drosophila model of cardiovascular disease

  2019influential citation
• Therapeutic Use of Bioengineered Materials for Myocardial Infarction

  2019cites this paper
• Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction

  2019cites this paper
• Supramolecular Modification of a Sequence-Controlled Collagen-Mimicking Polymer

  2019cites this paper
• Engineered bioactive nanoparticles incorporated biofunctionalized ECM/silk proteins based cardiac patches combined with MSCs for the repair of myocardial infarction: In vitro and in vivo evaluations.

  2019cites this paper
• Extracellular Matrix in Regulation of Contractile System in Cardiomyocytes

  2019cites this paper
• Biological Pathways and Gene Networks Link Inflammation and Vascular Remodeling to Both Heart Failure with Preserved and Reduced Ejection Fraction in Women across Ethnicities

  2019cites this paper
• Using Peptidomics to Identify Extracellular Matrix-Derived Peptides as Novel Therapeutics for Cardiac Disease

  2018cites this paper
• The Mouse Heart Attack Research Tool 1.0 database.

  2018cites this paper
• Current Trends in Biomaterial Utilization for Cardiopulmonary System Regeneration

  2018cites this paper
• Cardiomyogenic differentiation of human bone marrow-derived mesenchymal stem cell spheroids within electrospun collagen nanofiber mats.

  2018cites this paper
• Many Cells Make Life Work—Multicellularity in Stem Cell-Based Cardiac Disease Modelling

  2018cites this paper
• The interplay between cardiac progenitor cells and their microenvironment

  2018cites this paper
• Studies of the role of MAP kinase-activated protein kinase-5 (MK5) in reactive and reparative fibrosis in the murine heart

  2018cites this paper
• Left Ventricular Remodeling after Acute Myocardial Infarction and Biomarkers

  2017cites this paper
• Engineering Niches for Cardiovascular Tissue Regeneration

  2017cites this paper
• Renal ischemia/reperfusion-induced cardiac hypertrophy in mice: Cardiac morphological and morphometric characterization

  2017cites this paper
• Cardiac Progenitor Cells and the Interplay with Their Microenvironment

  2017cites this paper
• Molecular targets of dietary phytochemicals for possible prevention and therapy of uterine fibroids: Focus on fibrosis

  2017cites this paper
• Cardiac Fibroblast Activation Post-Myocardial Infarction: Current Knowledge Gaps.

  2017cites this paper
• Understanding cardiac extracellular matrix remodeling to develop biomarkers of myocardial infarction outcomes.

  2017cites this paper
• Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice

  2017cites this paper
• Farnesoid X receptor deletion improves cardiac function, structure and remodeling following myocardial infarction in mice

  2017cites this paper
• Dissecting the Roles of Periostin and TGFBI in Cardiovascular Disease

  2017influential citation
• CD36 Is a Matrix Metalloproteinase-9 Substrate That Stimulates Neutrophil Apoptosis and Removal During Cardiac Remodeling

  2016cites this paper
• How Biomaterials Can Influence Various Cell Types in the Repair and Regeneration of the Heart after Myocardial Infarction

  2016cites this paper
• Non-proliferative and Proliferative Lesions of the Cardiovascular System of the Rat and Mouse

  2016cites this paper
• A Collagen Matrix Promotes Anti-Inflammatory Healing Macrophage Function Through a miR-92a Mechanism

  2016influential citation
• Cardiac Tropism of Borrelia burgdorferi: An Autopsy Study of Sudden Cardiac Death Associated with Lyme Carditis.

  2016cites this paper
• Adapting extracellular matrix proteomics for clinical studies on cardiac remodeling post-myocardial infarction

  2016cites this paper
• Featured Article: Cardioprotective effects of lysyl oxidase inhibition against volume overload-induced extracellular matrix remodeling

  2016cites this paper
• May the fibrosis be with you: Is discoidin domain receptor 2 the receptor we have been looking for?

  2016cites this paper
• Matrix Therapies for Cell Support and Cardiac Repair

  2015cites this paper
• Targeting Osteopontin, the Silent Partner of Na+/H+ Exchanger Isoform 1 in Cardiac Remodeling

  2015cites this paper
• Novel xeno-free human heart matrix-derived three-dimensional scaffolds

  2015cites this paper
• A novel cardiac muscle-derived biomaterial reduces dyskinesia and postinfarct left ventricular remodeling in a mouse model of myocardial infarction

  2015cites this paper
• Tuning composition and architecture of biomimetic scaffolds for enhanced matrix synthesis by murine cardiomyocytes.

  2015cites this paper
• Early matrix metalloproteinase-12 inhibition worsens post-myocardial infarction cardiac dysfunction by delaying inflammation resolution.

  2015cites this paper
• Nanofibers based tissue engineering and drug delivery approaches for myocardial regeneration.

  2015cites this paper
• The Role of Extracellular Matrix in Cardiac Development

  2015cites this paper
• Biomaterials for Cardiac Regeneration

  2015cites this paper
• Abi3bp Regulates Cardiac Progenitor Cell Proliferation and Differentiation

  2014cites this paper
• From stem cells to cardiomyocytes: the role of forces in cardiac maturation, aging, and disease.

  2014cites this paper
• Cardiac extracellular proteome profiling and membrane topology analysis using glycoproteomics

  2014cites this paper
• Translating Koch's postulates to identify matrix metalloproteinase roles in postmyocardial infarction remodeling: cardiac metalloproteinase actions (CarMA) postulates.

  2014influential citation
• Phosphoproteomic Profiling of Human Myocardial Tissues Distinguishes Ischemic from Non-Ischemic End Stage Heart Failure

  2014cites this paper
• Autotomy of the Visceral Mass in the Feather Star Himerometra robustipinna (Crinoidea, Comatulida)

  2014cites this paper
• Reversible Modulation of Myofibroblast Differentiation in Adipose-Derived Mesenchymal Stem Cells

  2014cites this paper
• The interplay between the extracellular environment and cardiomyocyte progenitor cells for material based cardiac repair

  2013cites this paper
• In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing.

  2013cites this paper
• UvA-DARE ( Digital Academic Repository ) Monocytes in ischemic heart disease

  2013cites this paper
• A TRP to cardiac fibroblast differentiation

  2013cites this paper
• Macrophage-stem cell crosstalk after myocardial infarction.

  2013cites this paper
• Exposure to diesel exhaust particulates induces cardiac dysfunction and remodeling.

  2013cites this paper
• EDA-containing fibronectin levels in the cerebrospinal fluid of children with meningitis.

  2013cites this paper
• Reconstitution of the Myocardium in Regenerating Newt Hearts is Preceded by Transient Deposition of Extracellular Matrix Components

  2013influential citation
• The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction.

  2013cites this paper
• Proteases from the Regenerating Gut of the Holothurian Eupentacta fraudatrix

  2013cites this paper
• Extracellular Matrix Turnover Biomarkers Predict Long-Term Left Ventricular Remodeling After Myocardial Infarction: Insights From the REVE-2 Study

  2013cites this paper
• Monocyte and Macrophage Heterogeneity in the Heart

  2013cites this paper
• Regeneration in heart disease-Is ECM the key?

  2012cites this paper
• Extracellular Matrix and Fibroblast Communication Following Myocardial Infarction

  2012cites this paper
• Characterization of the Early Cellular Mechanisms Promoting Myocardial Fibrosis

  2012cites this paper
• Collagen XIV is important for growth and structural integrity of the myocardium.

  2012influential citation
• TIMP-2 gene transfer by positively charged PEG-lated monosized polycationic carrier to smooth muscle cells

  2012cites this paper
• PET/MRI of inflammation in myocardial infarction.

  2012cites this paper