Ischaemic preconditioning: from molecular characterisation to clinical application--part I.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Netherlands Journal of Medicine

• Publication date

  2004-11-01

• Fields of study

  Medicine

• Identifiers
  PMID 15683090
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein kinase activation and myocardial ischemia/reperfusion injury.

  2004cited by this paper
• NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.

  2004cited by this paper
• Postconditioning: A Form of “Modified Reperfusion” Protects the Myocardium by Activating the Phosphatidylinositol 3-Kinase–Akt Pathway

  2004cited by this paper
• INTERVENTIONAL CARDIOLOGY AND SURGERY Pharmacological modulation of the ATP sensitive potassium channels during repeated coronary occlusions: no effect on myocardial ischaemia or function

  2004cited by this paper
• Preconditioning protects by inhibiting the mitochondrial permeability transition.

  2004cited by this paper
• Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection.

  2004influential reference
• Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction.

  2004cited by this paper
• Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore.

  2004cited by this paper
• Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

  2004cited by this paper
• Primary and secondary signaling pathways in early preconditioning that converge on the mitochondria to produce cardioprotection.

  2004cited by this paper
• New concepts in reactive oxygen species and cardiovascular reperfusion physiology.

  2004cited by this paper
• Mitochondria in health and disease: perspectives on a new mitochondrial biology.

  2004influential reference
• Angina pectoris prior to myocardial infarction protects against subsequent left ventricular remodeling.

  2004cited by this paper
• Preinfarction angina does not alter infarct size and in hospital outcome after acute myocardial infarction with ST elevation.

  2004cited by this paper
• Transient Mitochondrial Permeability Transition Pore Opening Mediates Preconditioning-Induced Protection

  2004cited by this paper
• Evidence for Mitochondrial K Channels and Their Role in Cardioprotection

  2004influential reference
• Nicorandil induces late preconditioning against myocardial infarction in conscious rabbits.

  2004cited by this paper
• Protective and anti-protective effects of acute ethanol exposure in myocardial ischemia/reperfusion.

  2004cited by this paper
• New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway.

  2004cited by this paper
• Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both

  2004cited by this paper
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II.

  2003cited by this paper
• Role of the mitochondrial permeability transition in myocardial disease.

  2003cited by this paper
• KATP channels and myocardial preconditioning: an update.

  2003cited by this paper
• Novel pharmacological preconditioning with diazoxide attenuates myocardial stunning in coronary artery bypass grafting.

  2003cited by this paper
• From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I.

  2003cited by this paper
• Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning.

  2003cited by this paper
• Mechanisms of myocardial ischemic preconditioning are age related: PKC-epsilon does not play a requisite role in old rabbits.

  2003cited by this paper
• Antimalarial drugs and glucose metabolism.

  2003cited by this paper
• Anaesthetics and cardiac preconditioning. Part II. Clinical implications.

  2003cited by this paper
• Is impairment of ischaemic preconditioning by sulfonylurea drugs clinically important?

  2003cited by this paper
• Noninvasive remote ischemic preconditioning for global protection of skeletal muscle against infarction.

  2003cited by this paper
• Anaesthetics and cardiac preconditioning. Part I. Signalling and cytoprotective mechanisms.

  2003cited by this paper
• A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction.

  2003cited by this paper
• Effect of aspirin on late preconditioning against myocardial stunning in conscious rabbits.

  2003cited by this paper
• Protection of the human heart with ischemic preconditioning during cardiac surgery: role of cardiopulmonary bypass.

  2003cited by this paper
• Aging-related changes in myocardial purine metabolism and ischemic tolerance.

  2003cited by this paper
• Bradykinin, angiotensin-(1-7), and ACE inhibitors: how do they interact?

  2003cited by this paper
• Acute adenosinergic cardioprotection in ischemic-reperfused hearts.

  2003cited by this paper
• Preconditioning and cardiac surgery.

  2003cited by this paper
• The mitochondrial permeability transition pore: its fundamental role in mediating cell death during ischaemia and reperfusion.

  2003cited by this paper
• Ischaemic Preconditioning Inhibits Opening of Mitochondrial Permeability Transition Pores in the Reperfused Rat Heart

  2003cited by this paper
• Transient limb ischemia induces remote ischemic preconditioning in vivo.

  2003cited by this paper
• Frequency and clinical significance of ischemic preconditioning during percutaneous coronary intervention.

  2003cited by this paper
• Inhibiting mitochondrial permeability transition pore opening at reperfusion protects against ischaemia-reperfusion injury.

  2003cited by this paper
• Preconditioning the myocardium: from cellular physiology to clinical cardiology.

  2003influential reference
• Preconditioning by Sevoflurane Decreases Biochemical Markers for Myocardial and Renal Dysfunction in Coronary Artery Bypass Graft Surgery: A Double-blinded, Placebo-controlled, Multicenter Study

  2003cited by this paper
• Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathway.

  2003cited by this paper
• AT1-Receptor Antagonism Improves Endothelial Function in Coronary Artery Disease by a Bradykinin/B2-Receptor-Dependent Mechanism

  2003cited by this paper
• Inhibition of myocardial apoptosis reduces infarct size and improves regional contractile dysfunction during reperfusion.

  2003cited by this paper
• Impairment of myocardial protection in type 2 diabetic patients.

  2003cited by this paper
• Late preconditioning against myocardial stunning. Does aspirin close the "second window" of endogenous cardioprotection?

  2003cited by this paper
• Cochrane Review: Dipyridamole for Preventing Major Vascular Events in Patients With Vascular Disease

  2003cited by this paper
• Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men.

  2003cited by this paper
• Nonelectrocardiographic evidence that both ischemic preconditioning and adenosine preconditioning exist in humans.

  2003cited by this paper
• Influence of diabetic state and that of different sulfonylureas on the size of myocardial infarction with and without ischemic preconditioning in rabbits.

  2002cited by this paper
• Renal protection by brief liver ischemia in rats1

  2002cited by this paper
• Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice.

  2002cited by this paper
• Warm up phenomenon and preconditioning in clinical practice

  2002cited by this paper
• The importance of manganese superoxide dismutase in delayed preconditioning: involvement of reactive oxygen species and cytokines.

  2002cited by this paper
• Sites of action of adenosine in interorgan preconditioning of the heart.

  2002cited by this paper
• Statin Therapy in Acute Coronary Syndromes: Mechanistic Insight Into Clinical Benefit

  2002cited by this paper
• Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial.

  2002cited by this paper
• Apoptosis in myocardial ischaemia and infarction

  2002cited by this paper
• Preconditioning and arrhythmias.

  2002cited by this paper
• Hyperlipidemia prevents the expected reduction of myocardial ischemia on repeated balloon inflations during angioplasty.

  2002cited by this paper
• Ischemic preconditioning: a plea for rationally targeted clinical trials.

  2002cited by this paper
• Remote preconditioning by infrarenal occlusion of the aorta protects the heart from infarction: a newly identified non-neuronal but PKC-dependent pathway.

  2002cited by this paper
• Statin Prevents Tissue Factor Expression in Human Endothelial Cells: Role of Rho/Rho-Kinase and Akt Pathways

  2002cited by this paper
• Mitochondrial K(ATP) channels: role in cardioprotection.

  2002cited by this paper
• Intestinal ischemia preconditions myocardium: role of protein kinase C and mitochondrial K(ATP) channel.

  2002cited by this paper
• Delta opioid agonists and volatile anesthetics facilitate cardioprotection via potentiation of KATP channel opening

  2002cited by this paper
• Role of sarcolemmal KATP channels in cardioprotection against ischemia/reperfusion injury in mice

  2002cited by this paper
• Transient Limb Ischemia Induces Remote Ischemic Preconditioning In Vivo

  2002cited by this paper
• Differential Effects of Anesthetics on Mitochondrial KATP Channel Activity and Cardiomyocyte Protection

  2002cited by this paper
• Remote preconditioning protects the heart by activating myocardial PKCϵ-isoform

  2002cited by this paper
• Phosphorylation of Glycogen Synthase Kinase-3β During Preconditioning Through a Phosphatidylinositol-3-Kinase–Dependent Pathway Is Cardioprotective

  2002cited by this paper
• Inhibiting mitochondrial permeability transition pore opening: a new paradigm for myocardial preconditioning?

  2002cited by this paper
• Role of adenosine in delayed preconditioning of myocardium.

  2002cited by this paper
• Loss of Preconditioning by Attenuated Activation of Myocardial ATP-Sensitive Potassium Channels in Elderly Patients Undergoing Coronary Angioplasty

  2002cited by this paper
• Remote preconditioning protects the heart by activating myocardial PKCepsilon-isoform.

  2002cited by this paper
• Lovastatin Enhances Ecto-5′-Nucleotidase Activity and Cell Surface Expression in Endothelial Cells: Implication of Rho-Family GTPases

  2002cited by this paper
• Ischemic Preconditioning Suppresses Ventricular Tachyarrhythmias After Myocardial Revascularization

  2002cited by this paper
• Phosphorylation of Glycogen Synthase Kinase-3&bgr; During Preconditioning Through a Phosphatidylinositol-3-Kinase–Dependent Pathway Is Cardioprotective

  2002cited by this paper
• Cardioprotection at a distance: mesenteric artery occlusion protects the myocardium via an opioid sensitive mechanism.

  2002cited by this paper
• Isoflurane-induced preconditioning is attenuated by diabetes.

  2002cited by this paper
• The effect of preconditioning (ischemic and pharmacological) on myocardial necrosis following coronary artery bypass graft surgery.

  2002cited by this paper
• Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

  2002cited by this paper
• Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes.

  2002cited by this paper
• Long-term administration of nicorandil abolishes ischemic and pharmacologic preconditioning of the human myocardium: role of mitochondrial adenosine triphosphate-dependent potassium channels.

  2002cited by this paper
• Effects of free fatty acids on gluconeogenesis and autoregulation of glucose production in type 2 diabetes.

  2001cited by this paper
• Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors.

  2001cited by this paper
• Angiotensin-converting enzyme inhibition enhances a subthreshold stimulus to elicit delayed preconditioning in pig myocardium.

  2001cited by this paper
• Diabetes and hyperglycemia impair activation of mitochondrial K(ATP) channels.

  2001cited by this paper
• Naloxone blocks transferred preconditioning in isolated rabbit hearts.

  2001cited by this paper
• Does angina the week before protect against first myocardial infarction in elderly patients?

  2001cited by this paper
• Quantitative contributions of gluconeogenesis to glucose production during fasting in type 2 diabetes mellitus.

  2001cited by this paper
• No loss in the in vivo efficacy of ischemic preconditioning in middle-aged and old rabbits.

  2001cited by this paper
• Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research.

  2001cited by this paper
• Review article: Regulation of glucose production with special attention to nonclassical regulatory mechanisms: a review.

  2001cited by this paper
• Delayed Preconditioning-Mimetic Action of Nitroglycerin in Patients Undergoing Coronary Angioplasty

  2001cited by this paper

• Ischemic preconditioning enhances energy supply during frequency speed kick test in Taekwondo athletes: A randomized crossover study

  2026cites this paper
• Effects of 8-week ischemic preconditioning on swimming performance and power output in male 100-m freestyle swimmers: a randomized controlled trial

  2025cites this paper
• The effects of lower limb ischaemic preconditioning: a systematic review

  2024cites this paper
• Effects of occlusion pressure on hemodynamic responses recorded by near-infrared spectroscopy across two visits

  2024cites this paper
• Dexmedetomidine versus remifentanil in nasal surgery: a systematic review and meta-analysis

  2024cites this paper
• Targeting the opioid remifentanil: Protective effects and molecular mechanisms against organ ischemia-reperfusion injury.

  2023cites this paper
• Initial symptoms of vertebrobasilar artery occlusions and the outcomes after endovascular treatment

  2022cites this paper
• Effects of Recurring IPC vs. rIPC Maneuvers on Exercise Performance, Pulse Wave Velocity, and Red Blood Cell Deformability: Special Consideration of Reflow Varieties

  2022cites this paper
• Ischemic tolerance - blessing or curse.

  2021cites this paper
• Ischemic preconditioning of the muscle reduces the metaboreflex response of the knee extensors

  2021cites this paper
• Induction of ischemic tolerance by remote perconditioning or postconditioning as neuroprotective strategy for spinal cord motor neurons.

  2021cites this paper
• Effects of ischemic preconditioning on local hemodynamics and isokinetic muscular function

  2020cites this paper
• Effects of remote limb ischemic conditioning on muscle strength in healthy young adults: A randomized controlled trial

  2020cites this paper
• Enhancing exercise performance through ischaemic preconditioning

  2019cites this paper
• Effect of Compression Modalities for Recovery on Wrestlers Biomarkers in One Day Tournament

  2019cites this paper
• Remote ischemic postconditioning as well as blood plasma from double-conditioned donor ameliorate reperfusion syndrome in skeletal muscle

  2019cites this paper
• Effects of metformin on the heart with ischaemia-reperfusion injury: Evidence of its benefits from in vitro, in vivo and clinical reports.

  2019cites this paper
• Effect of Remote Ischemic Preconditioning on Maximal Exercise Tolerance in Young Adults

  2018cites this paper
• Nonautonomous dynamics of acute cell injury.

  2018cites this paper
• Pre-competition and recovery strategies in elite sport : the use of vascular occlusion and ischemic preconditioning

  2018cites this paper
• Inactivity Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans

  2017cites this paper
• Impact of lifelong exercise training on endothelial ischemia-reperfusion and ischemic preconditioning in humans.

  2017cites this paper
• Eplerenone does not limit ischemia-reperfusion injury in human myocardial tissue.

  2016cites this paper
• Postconditioning Effectively Prevents Trimethyltin Induced Neuronal Damage in the Rat Brain.

  2016cites this paper
• Ischaemic preconditioning in exercise and disease: One size fits all?

  2016cites this paper
• Remifentanil protects the ovaries against ischaemia-reperfusion injury in rats

  2016cites this paper
• ISCHEMIA-REPERFUSION Remifentanil protects uterus against ischemia-reperfusion injury in rats 1

  2015cites this paper
• Remifentanil protects uterus against ischemia-reperfusion injury in rats.

  2015cites this paper
• Interval exercise, but not endurance exercise, prevents endothelial ischemia-reperfusion injury in healthy subjects.

  2015cites this paper
• The impact of blood flow restricted exercise on the peripheral vasculature

  2014cites this paper
• Ionizing radiation as preconditioning against transient cerebral ischemia in rats.

  2014cites this paper
• Targeted Strategies to Fight Cardiac Aging

  2014cites this paper
• Cellular and Molecular Aspects of Cardioprotection

  2014cites this paper
• Adaptive protection against damage of preconditioning human umbilical cord-derived mesenchymal stem cells with hydrogen peroxide.

  2014cites this paper
• EXERCISE, PREVENTS ENDOTHELIAL ISCHEMIA-

  2014cites this paper
• Novel Translational Strategies to Treat Cardiac Injury and Dysfunction

  2014influential citation
• Bilateral Upper Limb Remote Ischemic Preconditioning Improves Peak Anaerobic Power in Recreationally Active Adults: 3347 May 31, 10

  2014cites this paper
• Blow up During Warm-up: Introduction of a Novel Method to Improve Athletic Performance

  2014cites this paper
• Is there anything positive about iatrogenic hypoglycemia in Type 1 diabetes

  2013cites this paper
• No renal protection from volatile-anesthetic preconditioning in open heart surgery

  2013influential citation
• Assessment of ischaemia and reperfusion injury

  2013cites this paper
• Ischemic preconditioning attenuates lipid peroxidation and apoptosis in the cecal ligation and puncture model of sepsis

  2013influential citation
• Metformin Therapy in Diabetes: The Role of Cardioprotection

  2013cites this paper
• Aging attenuates the protective effect of ischemic preconditioning against endothelial ischemia-reperfusion injury in humans.

  2013cites this paper
• Protective Effect of Metformin on Myocardial Injury in Metabolic Syndrome Patients following Percutaneous Coronary Intervention

  2013cites this paper
• Remote ischemic preconditioning prevents reduction in brachial artery flow-mediated dilation after strenuous exercise.

  2012cites this paper
• Effect of ischemic preconditioning on lactate accumulation and running performance.

  2012cites this paper
• exerciseartery flow-mediated dilation after strenuous Remote ischemic preconditioning prevents reduction in

  2012cites this paper
• Randomized controlled trial of laparoscopic gastric ischemic conditioning prior to minimally invasive esophagectomy, the LOGIC trial

  2012cites this paper
• Efficacy and mechanism of nicorandil in perioperative protection of skeletal muscle from ischaemia and reperfusion injury in a porcine model

  2012cites this paper
• Cystathionine γ-lyase and hypoxia : implicating hydrogen sulfide in the hypoxic stress response

  2012cites this paper
• The cardioprotective effects of metformin

  2011cites this paper
• Cardioprotection and Signaling Pathways

  2011cites this paper
• Anti-apoptosis and cell survival: a review.

  2011cites this paper
• Impact of remote ischemic preconditioning on wound healing in small bowel anastomoses.

  2011cites this paper
• Estudo da proteção renal com propofol e o isoflurano durante a esquemia e a reperfusão, com hiperglicemia transitória

  2011cites this paper
• Cardiac Adaptive Responses After Hypoxia in an Experimental Model

  2010cites this paper
• Role of Tumour Necrosis Factor Alpha (TNFa) in ischaemic and pharmacological postconditioning

  2010cites this paper
• The impairment of preconditioning-mediated cardioprotection in pathological conditions.

  2009cites this paper
• Adenosine-A1 Receptors Activation Restores the Suppressed Cardioprotective Effects of Ischemic Preconditioning in Hyperhomocysteinemic Rat Hearts

  2009cites this paper
• Effect of Noradrenalin and EGb 761 Pretreatment on the Ischemia-Reperfusion Injured Spinal Cord Neurons in Rabbits

  2009cites this paper
• Involvement of P2Y receptors in pyridoxal‐5′‐phosphate‐induced cardiac preconditioning

  2009cites this paper
• Postconditioning and Anticonditioning: Possibilities to Interfere to Evoked Apoptosis

  2009cites this paper
• [III Brazilian Guidelines on Chronic Heart Failure].

  2009cites this paper
• III Diretriz Brasileira de Insuficiência Cardíaca Crônica

  2009cites this paper
• Pediatric Myocardial Protection

  2009cites this paper
• Meccanismi di protezione delle cellule miocardiche dal danno da ischemia/riperfusione e potenziali implicazioni terapeutiche

  2009cites this paper
• Possible mechanisms for levosimendaninduced cardioprotection

  2008cites this paper
• Translational Research: Gene, Pharmacogenomics and Cell-Based Therapy in the Aging Heart

  2008cites this paper
• Adenosine and kidney function: Potential implications in patients with heart failure

  2008cites this paper
• The Opioidergic System: Potential Roles and Therapeutic Indications in the Eye

  2008cites this paper
• Ischemic preconditioning of the hindlimb or kidney does not attenuate the severity of acute ischemia/reperfusion-induced pancreatitis in rats.

  2008cites this paper
• Ischemic preconditioning produces systemic protective and adoptively transferable effects.

  2008cites this paper
• Comparison of two anoxia models in rainbow trout cells by a 2‐DE and MS/MS‐based proteome approach

  2008influential citation
• Ischaemic preconditioning during cardiac surgery: systematic review and meta-analysis of perioperative outcomes in randomised clinical trials.

  2008cites this paper
• Effect of low doses of alcohol on the warm-up phenomenon in patients with stable angina pectoris.

  2008cites this paper
• Physical training--beyond increasing exercise capacity.

  2008cites this paper
• Hypoxia and the heart : the role of nitric oxide in cardiac myocytes and endothelial cells

  2007cites this paper
• G-protein coupled receptor signaling in myocardium: not for the faint of heart.

  2007cites this paper
• Amelioration of diabetes by imatinib mesylate (Gleevec®): role of ‐cell NF‐KB activation and anti‐apoptotic preconditioning

  2007cites this paper
• Remote Preconditioning Reduces Microcirculatory Disorders in Pancreatic Ischemia/Reperfusion Injury

  2007cites this paper
• Ischemia-reperfusion-induced cardiac injury: a brief review.

  2007cites this paper
• CHAPTER 10 – Cellular Pathways and Molecular Events in Cardioprotection

  2007cites this paper
• Amelioration of diabetes by imatinib mesylate (Gleevec (cid:1) ): role of (cid:1) -cell NF- (cid:2) B activation and anti-apoptotic preconditioning

  2007cites this paper
• Amelioration of diabetes by imatinib mesylate (Gleevec): role of beta-cell NF-kappaB activation and anti-apoptotic preconditioning.

  2007cites this paper
• Anti-diabetic and beta-cell protective actions of imatinib mesylate.

  2006cites this paper
• Outcome of coronary revascularisation in diabetes.

  2006cites this paper
• Potential biomarkers for ischemic heart damage identified in mitochondrial proteins by comparative proteomics

  2006cites this paper
• The Changes in Endogenous Antioxidant Enzyme Activity After Postconditioning

  2006cites this paper
• Emerging therapies for the management of decompensated heart failure: from bench to bedside.

  2006influential citation
• Delayed Postconditionig Initiates Additive Mechanism Necessary for Survival of Selectively Vulnerable Neurons After Transient Ischemia in Rat Brain

  2006cites this paper
• Distribution and Functional Characterization of Equilibrative Nucleoside Transporter-4, a Novel Cardiac Adenosine Transporter Activated at Acidic pH

  2006cites this paper
• merging Therapies for the anagement of Decompensated Heart Failure rom Bench

  2006influential citation
• Is remote preconditioning as effective as direct ischemic preconditioning in preventing spinal cord ischemic injury?

  2006cites this paper
• Oral therapy with dipyridamole limits ischemia‐reperfusion injury in humans

  2005cites this paper
• Evidence for a Role of Second Pathophysiological Stress in Prevention of Delayed Neuronal Death in the Hippocampal CA1 Region

  2005cites this paper
• Dehydroepiandrosterone administration in humans: evidence based?

  2005cites this paper
• Reduced adenosine receptor stimulation as a pathogenic factor in hyperhomocysteinemia

  2005cites this paper
• Ischaemic preconditioning: from molecular characterisation to clinical application--part II.

  2004cites this paper
• Overview of the various in vitro and in vivo models of ischaemic preconditioning in humans with main endpoints and limitations

  2004cites this paper