Importin α associates with membranes and participates in nuclear envelope assembly in vitro

No abstract is available for this paper.

• Publication year

  2004

• Venue

  EMBO Journal

• Publication date

  2004-04-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.emboj.7600154PMID 15014441PMCID PMC391064
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sorting out the nuclear envelope from the endoplasmic reticulum

  2004cited by this paper
• RanGTP mediates nuclear pore complex assembly

  2003cited by this paper
• Nanoelectrospray-based detection and sequencing of substoichiometric amounts of phosphopeptides in complex mixtures.

  2003cited by this paper
• Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly.

  2003cited by this paper
• P446L-importin-beta inhibits nuclear envelope assembly by sequestering nuclear envelope assembly factors to the microtubules.

  2003cited by this paper
• The small GTPase Ran: interpreting the signs.

  2003cited by this paper
• The importin-beta P446L dominant-negative mutant protein loses RanGTP binding ability and blocks the formation of intact nuclear envelope.

  2002cited by this paper
• A role for Caenorhabditis elegans importin IMA-2 in germ line and embryonic mitosis.

  2002cited by this paper
• The GTPase Ran regulates chromosome positioning and nuclear envelope assembly in vivo.

  2002cited by this paper
• Role of Importin-β in the Control of Nuclear Envelope Assembly by Ran

  2002cited by this paper
• The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly

  2002cited by this paper
• Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains

  2002cited by this paper
• Ran GTPase cycle and importins alpha and beta are essential for spindle formation and nuclear envelope assembly in living Caenorhabditis elegans embryos.

  2002influential reference
• Importin-alpha 2 is critically required for the assembly of ring canals during Drosophila oogenesis.

  2002cited by this paper
• Role of importin-beta in the control of nuclear envelope assembly by Ran.

  2002cited by this paper
• Importin-α2 is critically required for the assembly of ring canals during Drosophila oogenesis

  2002cited by this paper
• Inner nuclear membrane proteins and the nuclear lamina.

  2001cited by this paper
• Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly

  2001cited by this paper
• Inner nuclear membrane proteins: functions and targeting

  2001cited by this paper
• Ran Induces Spindle Assembly by Reversing the Inhibitory Effect of Importin α on TPX2 Activity

  2001influential reference
• Importin β Is a Mitotic Target of the Small GTPase Ran in Spindle Assembly

  2001cited by this paper
• Importin beta is a mitotic target of the small GTPase Ran in spindle assembly.

  2001cited by this paper
• Ran induces spindle assembly by reversing the inhibitory effect of importin alpha on TPX2 activity.

  2001cited by this paper
• Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts.

  2000cited by this paper
• GTP hydrolysis by Ran is required for nuclear envelope assembly.

  2000cited by this paper
• Transport between the cell nucleus and the cytoplasm.

  1999influential reference
• Mutations in fission yeast Cut15, an importin alpha homolog, lead to mitotic progression without chromosome condensation.

  1998cited by this paper
• Phosphorylation of Srp1p, the yeast nuclear localization signal receptor, in vitro and in vivo.

  1997cited by this paper
• Nuclear envelope assembly after mitosis.

  1997cited by this paper
• Nuclear envelope assembly in Xenopus extracts visualized by scanning EM reveals a transport-dependent 'envelope smoothing' event.

  1997cited by this paper
• Integral Membrane Proteins of the Nuclear Envelope Are Dispersed throughout the Endoplasmic Reticulum during Mitosis

  1997cited by this paper
• Nuclear Membrane Dynamics and Reassembly in Living Cells: Targeting of an Inner Nuclear Membrane Protein in Interphase and Mitosis

  1997cited by this paper
• Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels.

  1996cited by this paper
• 16-BAC/SDS-PAGE: a two-dimensional gel electrophoresis system suitable for the separation of integral membrane proteins.

  1996cited by this paper
• Isolation of a yeast protein kinase that is activated by the protein encoded by SRP1 (Srp1p) and phosphorylates Srp1p complexed with nuclear localization signal peptides.

  1995cited by this paper
• Isolation of a protein that is essential for the first step of nuclear protein import.

  1994cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Golgi_traff phylogeny reveals ancient eukaryotic genes with recent surprises: replication and diversification of HID1 domain-containing protein unique to Schizosaccharomyces

  2025cites this paper
• Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway.

  2025cites this paper
• The localisation and stability of the CENP-F protein are regulated by importin beta and microtubules in mitotic cells

  2025cites this paper
• Normal male fertility in a mouse model of KPNA2 deficiency

  2024cites this paper
• Distribution of importin-α isoforms in poultry species and their tissue- and age-related differences.

  2023cites this paper
• Loss of the importin Kpna2 causes infertility in male mice by disrupting the translocation of testis-specific transcription factors

  2023cites this paper
• Maize DDK1 encoding an Importin-4 β protein is essential for seed development and grain filling by mediating nuclear exporting of eIF1A.

  2023cites this paper
• KPNA2 promotes angiogenesis by regulating STAT3 phosphorylation

  2022cites this paper
• Membrane association of importin α facilitates viral entry into salivary gland cells of vector insects

  2021cites this paper
• SWO1 modulates cell wall integrity under salt stress by interacting with importin ɑ in Arabidopsis

  2021cites this paper
• Importin α phosphorylation promotes TPX2 activation by GM130 to control astral microtubules and spindle orientation

  2021cites this paper
• More than a zip code: global modulation of cellular function by nuclear localization signals

  2020cites this paper
• Selective Nuclear Pore Complex Removal Drives Nuclear Envelope Division in Fission Yeast.

  2020cites this paper
• TPX2 activation by GM130 controls astral microtubule formation and spindle orientation

  2020cites this paper
• Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α

  2019cites this paper
• Importin α Partitioning to the Plasma Membrane Regulates Intracellular Scaling.

  2019cites this paper
• Importin α: functions as a nuclear transport factor and beyond

  2018cites this paper
• Myosin‐1C uses a novel phosphoinositide‐dependent pathway for nuclear localization

  2018cites this paper
• Depletion of nuclear import protein karyopherin alpha 7 (KPNA7) induces mitotic defects and deformation of nuclei in cancer cells

  2018cites this paper
• The effect of nanoparticle size and NLS density on nuclear targeting in cancer and normal cells; impaired nuclear import and aberrant nanoparticle intracellular trafficking in glioma

  2017cites this paper
• Importin α: a key molecule in nuclear transport and non-transport functions.

  2016cites this paper
• Neurospora chromosomes are organized by blocks of importin alpha-dependent heterochromatin that are largely independent of H3K9me3

  2016cites this paper
• Comparative Proteomic Analysis of Soybean Leaves and Roots by iTRAQ Provides Insights into Response Mechanisms to Short-Term Salt Stress

  2016cites this paper
• Nuclear transport factors: global regulation of mitosis.

  2015cites this paper
• GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules.

  2015cites this paper
• Reprint of "Nuclear transport factors: global regulation of mitosis".

  2015cites this paper
• Neurospora Importin α Is Required for Normal Heterochromatic Formation and DNA Methylation

  2015cites this paper
• Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

  2015cites this paper
• Purification of nuclear localization signal-containing proteins and its application to investigation of the mechanisms of the cell division cycle

  2015cites this paper
• Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts.

  2015cites this paper
• Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration

  2014cites this paper
• The α‐importome of mammalian germ cell maturation provides novel insights for importin biology

  2014cites this paper
• Ran GTPase in nuclear envelope formation and cancer metastasis.

  2014cites this paper
• Mitotic spindle scaling during Xenopus development by kif2a and importin α

  2013cites this paper
• Cloning and Characterization of Importin α in Brassica napus L.

  2013cites this paper
• spindle scaling during development by kif2a and importin α.

  2013cites this paper
• Identification of Novel Stress Granule Components That Are Involved in Nuclear Transport

  2013cites this paper
• Intranuclear DNA density affects chromosome condensation in metazoans

  2013cites this paper
• Regulated nucleocytoplasmic transport during gametogenesis.

  2012cites this paper
• Chromatin-bound NLS proteins recruit membrane vesicles and nucleoporins for nuclear envelope assembly via importin-α/β

  2012cites this paper
• Changing subcellular localization of nuclear transport factors during human spermatogenesis.

  2012cites this paper
• Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development

  2011cites this paper
• Nuclear retention of importin α coordinates cell fate through changes in gene expression

  2011cites this paper
• A dominant-negative form of POM121 binds chromatin and disrupts the two separate modes of nuclear pore assembly

  2011cites this paper
• Expression of nucleocytoplasmic transport machinery: clues to regulation of spermatogenic development.

  2011cites this paper
• Localization of retinitis pigmentosa 2 to cilia is regulated by Importin β2

  2011cites this paper
• Truncated Isoforms of Kap60 Facilitate Trafficking of Heh2 to the Nuclear Envelope

  2010cites this paper
• NLS‐mediated NPC functions of the nucleoporin Pom121

  2010cites this paper
• Identification of importin alpha1 as a novel constituent of RNA stress granules.

  2010cites this paper
• Recognition of nucleoplasmin by its nuclear transport receptor importin α/β: insights into a complete import complex.

  2010cites this paper
• Nuclear Size Is Regulated by Importin and Ntf2 in Xenopus

  2010cites this paper
• C-terminal armadillo repeats are essential and sufficient for association of the plant U-box armadillo E3 ubiquitin ligase SAUL1 with the plasma membrane

  2010cites this paper
• Double duty for nuclear proteins--the price of more open forms of mitosis.

  2009cites this paper
• Interplay between the transmembrane nucleoporin Pom121 and the Ran GTPase system

  2009cites this paper
• The role of MEL-28 in nuclear pore complex formation

  2009cites this paper
• Nucleocytoplasmic shuttling of ecdysteroid receptor

  2008cites this paper
• Baculovirus Data Suggest a Common but Multifaceted Pathway for Sorting Proteins to the Inner Nuclear Membrane

  2008cites this paper
• Novel expression of importin alpha homologue in marine teleost, Pagrus major.

  2008cites this paper
• Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly

  2008cites this paper
• BACULOVIRUS SUGGESTS A COMMON BUT MULTI-2 FACETED PATHWAY FOR SORTING PROTEINS TO THE 3 INNER NUCLEAR MEMBRANE 4 5

  2008cites this paper
• Regulation of Nuclear Lamin Polymerization by Importin α*

  2008cites this paper
• Spatial and temporal coordination of mitosis by Ran GTPase

  2008cites this paper
• Breakdown and Reformation of the Nuclear Envelope

  2007cites this paper
• Proteomic profiling of murine oocyte maturation

  2007cites this paper
• Spatial control of mitosis by the GTPase Ran

  2007cites this paper
• Nucleocytoplasmic shuttling of ecdysteroid receptor

  2007cites this paper
• CK2 phosphorylation weakens 90 kDa MFP1 association to the nuclear matrix in Allium cepa.

  2006influential citation
• The conserved transmembrane nucleoporin NDC1 is required for nuclear pore complex assembly in vertebrate cells.

  2006cites this paper
• In vitro study of nuclear assembly and nuclear import using Xenopus egg extracts.

  2006cites this paper
• The nuclear envelope: form and reformation.

  2006cites this paper
• Importin-α-16 is a translocon-associated protein involved in sorting membrane proteins to the nuclear envelope

  2006cites this paper
• Domains of Importin-α2 required for ring canal assembly during Drosophila oogenesis

  2006cites this paper
• Domains of Importin-alpha2 required for ring canal assembly during Drosophila oogenesis.

  2006cites this paper
• Nuclear Localization Signal and Protein Context both Mediate Importin α Specificity of Nuclear Import Substrates

  2006cites this paper
• TPX2 is required for postmitotic nuclear assembly in cell-free Xenopus laevis egg extracts

  2006cites this paper
• Histone acetylase GCN5 enters the nucleus via importin-alpha in protozoan parasite Toxoplasma gondii.

  2005cites this paper
• Pushing the envelope: structure, function, and dynamics of the nuclear periphery.

  2005cites this paper
• Histone Acetylase GCN5 Enters the Nucleus via Importin-α in Protozoan Parasite Toxoplasma gondii*

  2005cites this paper
• The Fission Yeast Schizosaccharomyces pombe Has Two Importin-α Proteins, Imp1p and Cut15p, Which Have Common and Unique Functions in Nucleocytoplasmic Transport and Cell Cycle Progression

  2005cites this paper
• Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3

  2005cites this paper
• The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation.

  2005cites this paper
• Characterization of two nima interacting proteins suggests a link between nima and nuclear membrane fission

  2004cites this paper
• Importin α: A multipurpose nuclear-transport receptor

  2004cites this paper
• Potential Link between the NIMA Mitotic Kinase and Nuclear Membrane Fission during Mitotic Exit in Aspergillus nidulans

  2004cites this paper
• Importin alpha: a multipurpose nuclear-transport receptor.

  2004cites this paper
• Importin beta: conducting a much larger cellular symphony.

  2004cites this paper
• Jcb: Article Introduction

  2002cites this paper