Poly ADP-ribose polymerase-1: Beyond transcription and towards differentiation.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Seminars in Cell and Developmental Biology

• Publication date

  2017-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.semcdb.2016.07.027PMID 27476447
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Poly‐ADP‐ribose polymerase inhibition enhances ischemic and diabetic wound healing by promoting angiogenesis

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• ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β

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• The PARP family: insights into functional aspects of poly (ADP‐ribose) polymerase‐1 in cell growth and survival

  2016cited by this paper
• Involvement of PARP1 in the regulation of alternative splicing

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• A PARP1-ERK2 synergism is required for the induction of LTP

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• Poly (ADP-ribose) polymerase1 regulates growth and multicellularity in D. discoideum.

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• A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors.

  2015cited by this paper
• NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus.

  2015cited by this paper
• Transcription of the Human Microsomal Epoxide Hydrolase Gene (EPHX1) Is Regulated by PARP-1 and Histone H1.2. Association with Sodium-Dependent Bile Acid Transport

  2015cited by this paper
• PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.

  2015cited by this paper
• Response of Dictyostelium discoideum to UV‐C and involvement of poly (ADP‐ribose) polymerase

  2015cited by this paper
• Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2

  2015cited by this paper
• Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling

  2014cited by this paper
• Interaction between PARP-1 and HIF-2α in the hypoxic response

  2014cited by this paper
• Distribution of protein poly(ADP-ribosyl)ation systems across all domains of life

  2014cited by this paper
• ARTD1-induced poly-ADP-ribose formation enhances PPARγ ligand binding and co-factor exchange

  2014cited by this paper
• The PARP1/ARTD1-Mediated Poly-ADP-Ribosylation and DNA Damage Repair in B Cell Diversification

  2014cited by this paper
• Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.

  2014cited by this paper
• GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation

  2014cited by this paper
• Automodification switches PARP-1 function from chromatin architectural protein to histone chaperone

  2014cited by this paper
• Kinase-mediated changes in nucleosome conformation trigger chromatin decondensation via poly(ADP-ribosyl)ation.

  2014cited by this paper
• Proteases involved during oxidative stress-induced poly(ADP-ribose) polymerase-mediated cell death in Dictyostelium discoideum.

  2014cited by this paper
• Post-Transcriptional Regulation by Poly(ADP-ribosyl)ation of the RNA-Binding Proteins

  2013cited by this paper
• Effects of PARP-1 Deficiency on Th1 and Th2 Cell Differentiation

  2013cited by this paper
• PARP1 represses PAP and inhibits polyadenylation during heat shock.

  2013cited by this paper
• ADP-ribose polymer depletion leads to nuclear Ctcf re-localization and chromatin rearrangement(1).

  2013cited by this paper
• Beyond DNA repair, the immunological role of PARP‐1 and its siblings

  2013cited by this paper
• Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases

  2013cited by this paper
• Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

  2013cited by this paper
• Connections between chromatin signatures and splicing

  2013cited by this paper
• Involvement of poly(ADP-ribose) polymerase in paraptotic cell death of D. discoideum

  2013cited by this paper
• PARP-1 regulates expression of TGF-β receptors in T cells.

  2013cited by this paper
• Activator-induced spread of poly(ADP-ribose) polymerase promotes nucleosome loss at Hsp70.

  2012cited by this paper
• Inheritance of silent rDNA chromatin is mediated by PARP1 via noncoding RNA.

  2012cited by this paper
• Alternative Modes of Binding of Poly(ADP-ribose) Polymerase 1 to Free DNA and Nucleosomes*

  2012cited by this paper
• New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

  2012cited by this paper
• Role of poly(ADP‐ribose) polymerases in the regulation of inflammatory processes

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• Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

  2012cited by this paper
• Insights into RNA biology from an atlas of mammalian mRNA-binding proteins.

  2012cited by this paper
• Poly(ADP-ribose)polymerase-1 (PARP1) controls adipogenic gene expression and adipocyte function.

  2012cited by this paper
• Histone ADP-Ribosylation Facilitates Gene Transcription by Directly Remodeling Nucleosomes

  2012cited by this paper
• Regulation of Poly(ADP-ribose) Polymerase-1-dependent Gene Expression through Promoter-directed Recruitment of a Nuclear NAD+ Synthase*

  2012cited by this paper
• ARTD1 deletion causes increased hepatic lipid accumulation in mice fed a high‐fat diet and impairs adipocyte function and differentiation

  2012cited by this paper
• Staurosporine induced poly (ADP-ribose) polymerase independent cell death in Dictyostelium discoideum.

  2012cited by this paper
• Fibroblast Growth Factor Regulates Human Neuroectoderm Specification Through ERK1/2‐PARP‐1 Pathway

  2011cited by this paper
• Overexpression of PaParp encoding the poly(ADP-ribose) polymerase of Podospora anserina affects organismal aging.

  2011cited by this paper
• Poly(ADP-ribose) Metabolism Is Essential for Proper Nucleoprotein Exchange During Mouse Spermiogenesis1

  2011cited by this paper
• Drosophila histone H2A variant (H2Av) controls poly(ADP-ribose) polymerase 1 (PARP1) activation in chromatin

  2011cited by this paper
• ADP-ribose polymers localized on Ctcf–Parp1–Dnmt1 complex prevent methylation of Ctcf target sites

  2011cited by this paper
• PARP regulates nonhomologous end joining through retention of Ku at double-strand breaks

  2011cited by this paper
• Poly (ADP-ribose) polymerase-1 (PARP-1) as immune regulator.

  2011cited by this paper
• SIRT6 Promotes DNA Repair Under Stress by Activating PARP1

  2011cited by this paper
• Poly(ADP-ribose) Polymerase 1 Is Indispensable for Transforming Growth Factor-β Induced Smad3 Activation in Vascular Smooth Muscle Cell

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• RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling

  2011cited by this paper
• Differential Role of Poly(ADP-ribose) polymerase in D. discoideum growth and development

  2011cited by this paper
• Functions of the poly(ADP-ribose) polymerase superfamily in plants

  2011cited by this paper
• Structural and Evolutionary Analysis of PARPs in D. discoideum

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• PARP is involved in replicative aging in Neurospora crassa.

  2010cited by this paper
• PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway.

  2010cited by this paper
• PARP-1 attenuates Smad-mediated transcription.

  2010cited by this paper
• The roles of PARP1 in gene control and cell differentiation.

  2010cited by this paper
• Increased Foxp3+ Regulatory T Cells in Poly(ADP-Ribose) Polymerase-1 Deficiency

  2010cited by this paper
• Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

  2010cited by this paper
• Oocyte Numbers in the Mouse Increase after Treatment with 5-Aminoisoquinolinone: A Potent Inhibitor of Poly(ADP-ribosyl)ation1

  2010cited by this paper
• Uncoupling of the transactivation and transrepression functions of PARP1 protein

  2010cited by this paper
• Toward a unified nomenclature for mammalian ADP-ribosyltransferases.

  2010cited by this paper
• Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes

  2010cited by this paper
• The Zn3 Domain of Human Poly(ADP-ribose) Polymerase-1 (PARP-1) Functions in Both DNA-dependent Poly(ADP-ribose) Synthesis Activity and Chromatin Compaction*

  2010cited by this paper
• The molecular machinery of germ line specification

  2010cited by this paper
• The PARP side of the nucleus: molecular actions, physiological outcomes, and clinical targets.

  2010cited by this paper
• PARP inhibition: PARP1 and beyond

  2010cited by this paper
• Post‐ischemic brain damage: targeting PARP‐1 within the ischemic neurovascular units as a realistic avenue to stroke treatment

  2009cited by this paper
• Poly (ADP-ribose) glycohydrolase (PARG) and its therapeutic potential.

  2009cited by this paper
• Poly(ADP-ribose) signals to mitochondrial AIF: a key event in parthanatos.

  2009cited by this paper
• Poly (ADP-Ribose) Polymerase 1 Is Required for Protein Localization to Cajal Body

  2009cited by this paper
• Poly(ADP-ribosyl)ation of heterogeneous nuclear ribonucleoproteins modulates splicing

  2009cited by this paper
• A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

  2009cited by this paper
• Global Analysis of Transcriptional Regulation by Poly(ADP-ribose) Polymerase-1 and Poly(ADP-ribose) Glycohydrolase in MCF-7 Human Breast Cancer Cells*♦

  2009cited by this paper
• PARP1 Poly(ADP-ribosyl)ates Sox2 to Control Sox2 Protein Levels and FGF4 Expression during Embryonic Stem Cell Differentiation*

  2009cited by this paper
• A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation.

  2009cited by this paper
• Disruption of Poly(ADP-Ribose) Homeostasis Affects Spermiogenesis and Sperm Chromatin Integrity in Mice1

  2009cited by this paper
• Epigenetics: poly(ADP‐ribosyl)ation of PARP‐1 regulates genomic methylation patterns

  2009cited by this paper
• CCCTC‐binding factor meets poly(ADP‐ribose) polymerase‐1

  2009cited by this paper
• Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE

  2009cited by this paper
• Persistence of histone H2AX phosphorylation after meiotic chromosome synapsis and abnormal centromere cohesion in poly (ADP-ribose) polymerase (Parp-1) null oocytes.

  2009cited by this paper
• Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler

  2009cited by this paper
• Regulation of NFAT by poly(ADP-ribose) polymerase activity in T cells.

  2008cited by this paper
• Poly(ADP-ribose) Binds to the Splicing Factor ASF/SF2 and Regulates Its Phosphorylation by DNA Topoisomerase I*

  2008cited by this paper
• The Cajal body.

  2008cited by this paper
• Regulation of Transcription Factor NFAT by ADP-Ribosylation

  2008cited by this paper
• Rapid, transcription-independent loss of nucleosomes over a large chromatin domain at Hsp70 loci.

  2008cited by this paper
• Activation and overexpression of PARP-1 in circulating mononuclear cells promote TNF-alpha and IL-6 expression in patients with unstable angina.

  2008cited by this paper
• Transcriptional regulation by Poly(ADP-ribose) polymerase-1 during T cell activation

  2008cited by this paper
• Reciprocal Binding of PARP-1 and Histone H1 at Promoters Specifies Transcriptional Outcomes

  2008cited by this paper
• The complex of TFII‐I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia

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• The histone subcode: poly(ADP‐ribose) polymerase‐1 (Parp‐1) and Parp‐2 control cell differentiation by regulating the transcriptional intermediary factor TIF1β and the heterochromatin protein HPlα

  2008cited by this paper
• A Third Zinc-binding Domain of Human Poly(ADP-ribose) Polymerase-1 Coordinates DNA-dependent Enzyme Activation*

  2008cited by this paper
• Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction

  2007cited by this paper
• Effect of oxidative stress and involvement of poly(ADP‐ribose) polymerase (PARP) in Dictyostelium discoideum development

  2007cited by this paper
• DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation.

  2007cited by this paper

• PARPs and PARP inhibitors: molecular mechanisms and clinical applications

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• The need for speed: drivers and consequences of accelerated replication forks

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• The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation

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• Transcriptional regulation mechanism of PARP1 and its application in disease treatment

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• Design, Synthesis, and Evaluation of [18F]BIBD-300 as a Positron Emission Tomography Tracer for Poly(ADP-Ribose) Polymerase-1.

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• A new wave of innovations within the DNA damage response

  2023cites this paper
• Liquid-liquid phase separation in DNA double-strand breaks repair

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• Cell-Based Screening for New PARP Inhibitors Utilizing PARG-Mutated Mouse Embryonic Stem Cells.

  2023cites this paper
• PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response

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• MACC1 and Gasdermin-E (GSDME) regulate the resistance of colorectal cancer cells to irinotecan.

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• Suppression of oxidative-stress induced melanocyte death: Role of poly(ADP-ribose) polymerase in vitiligo pathogenesis.

  2022cites this paper
• Upregulation of PARG in prostate cancer cells suppresses their malignant behavior and downregulates tumor-promoting genes.

  2022cites this paper
• NAD+ supplementation reverses the oxidative stress induced PARP1 signalling in D. discoideum

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• Specific decellularized extracellular matrix promotes the plasticity of human ocular surface epithelial cells

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• Promising drug repurposing approach targeted for cytokine storm implicated in SARS-CoV-2 complications

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• Identification and characterization of Poly(ADP-ribose) polymerase-1 interacting proteins during development of Dictyostelium discoideum.

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• Poly (ADP-Ribose) Polymerase 1 Regulates Cajal–Retzius Cell Development and Neural Precursor Cell Adhesion

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• Effects of DNA Methylation on TFs in Human Embryonic Stem Cells

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• Role of PARP-1 in mitochondrial homeostasis.

  2020cites this paper
• Poly(ADP-ribose) polymerase inhibition: past, present and future

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• Poly(ADP-ribose) Polymerase 1 (PARP1) restrains MyoD-dependent gene expression during muscle differentiation

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• Need for NAD+: Focus on Striated Muscle Laminopathies

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• Signaling interplay between PARP1 and ROS regulates stress-induced cell death and developmental changes in Dictyostelium discoideum.

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• Poly(ADP-ribose) polymerase inhibition: past, present and future

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• Insights into the functional aspects of Poly(ADP-ribose) polymerase-1 (PARP-1) in mitochondrial homeostasis in Dictyostelium discoideum.

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• Glimpses of Dictyostelid research in India.

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• An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

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• Poly(ADP-ribose) polymerase enzymes and the maintenance of genome integrity

  2019cites this paper
• Role of PARP-catalyzed ADP-ribosylation in the crosstalk between DNA strand breaks and epigenetic regulation.

  2019cites this paper
• Poly(ADP‐ribose) polymerase‐1 (PARP‐1) regulates developmental morphogenesis and chemotaxis in Dictyostelium discoideum

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• Regulation of Glucose Metabolism by NAD+ and ADP-Ribosylation

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• Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

  2018cites this paper
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• PARP activity and inhibition in fetal and adult oligodendrocyte precursor cells: Effect on cell survival and differentiation.

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