A Density-Driven Method for the Placement of Biological Cells Over Two-Dimensional Manifolds

We introduce a graphical method originating from the computer graphics domain that is used for the arbitrary placement of cells over a two-dimensional manifold. Using a bitmap image whose luminance provides cell density, this method guarantees a discrete distribution of the positions of the cells respecting the local density. This method scales to any number of cells, allows one to specify arbitrary enclosing shapes and provides a scalable and versatile alternative to the more classical assumption of a uniform spatial distribution. The method is illustrated on a discrete homogeneous neural field, on the distribution of cones and rods in the retina and on the neural density of a flattened piece of cortex.

• Publication year

  2017

• Venue

  Front. Neuroinform.

• Publication date

  2017-10-14

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.3389/fninf.2018.00012arXiv 1710.05189PMID 29615887PMCID 5869184
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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