Identification of peptide sequences that potentially trigger HLA‐A2.1‐restricted cytotoxic T lymphocytes

No abstract is available for this paper.

• Publication year

  1993

• Venue

  European Journal of Immunology

• Publication date

  1993-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/EJI.1830230603PMID 7684681
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of the nonamer peptide from influenza A matrix protein and the role of pockets of HLA‐A2 in its recognition by cytotoxic T lymphocytes

  1992cited by this paper
• HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

  1992cited by this paper
• Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry.

  1992cited by this paper
• CD8+ T cells specific for a single nonamer epitope of Listeria monocytogenes are protective in vivo

  1992cited by this paper
• New genes in the MHC that encode proteins for antigen processing.

  1992cited by this paper
• Tumor eradication by adoptive transfer of cytotoxic T lymphocytes.

  1992cited by this paper
• Immunization against polyoma tumors with synthetic peptides derived from the sequences of middle‐and large‐T antigens

  1992cited by this paper
• Peptide and beta 2-microglobulin regulation of cell surface MHC class I conformation and expression.

  1992cited by this paper
• Solution binding of an antigenic peptide to a major histocompatibility complex class I molecule and the role of beta 2-microglobulin.

  1992cited by this paper
• HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation.

  1992cited by this paper
• Preferred size of peptides that bind to H‐2 Kb is sequence dependent

  1992cited by this paper
• Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein.

  1991cited by this paper
• Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

  1991cited by this paper
• Peptide loading of empty major histocompatibility complex molecules on RMA‐S cells allows the induction of primary cytotoxic T lymphocyte responses

  1991cited by this paper
• Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.

  1991cited by this paper
• Fine specificity of cytotoxic T lymphocytes primed in vivo either with virus or synthetic lipopeptide vaccine or primed in vitro with peptide

  1991cited by this paper
• Peptide-induced antiviral protection by cytotoxic T cells.

  1991cited by this paper
• In vivo efficacy of virus-derived peptides and virus-specific cytotoxic T lymphocytes.

  1991cited by this paper
• The structure of the antigen-binding groove of major histocompatibility complex class I molecules determines specific selection of self-peptides.

  1991cited by this paper
• Assembly of MHC class I molecules analyzed in vitro.

  1990cited by this paper
• Defective presentation of endogenous antigen by a cell line expressing class I molecules.

  1990cited by this paper
• A nucleoprotein peptide of influenza A virus stimulates assembly of HLA-B27 class I heavy chains and β2-micro-globulin translated in vitro

  1990cited by this paper
• Isolation and analysis of naturally processed viral peptides as recognized by cytotoxic T cells

  1990cited by this paper
• The binary logic of antigen processing and presentation to T cells.

  1990cited by this paper
• Presentation of viral antigen controlled by a gene in the major histocompatibility complex

  1990cited by this paper
• Antigen recognition by class I-restricted T lymphocytes.

  1989cited by this paper
• Association of class I major histocompatibility heavy and light chains induced by viral peptides

  1989cited by this paper
• Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation

  1989cited by this paper
• Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytes.

  1989cited by this paper
• Specific associations of fluorescent beta-2-microglobulin with cell surfaces. The affinity of different H-2 and HLA antigens for beta-2-microglobulin.

  1988cited by this paper
• Allele and locus‐specific differences in cell surface expression and the association of HLA class I heavy chain with β2‐microglobulin: differential effects of inhibition of glycosylation on class I subunit association

  1988cited by this paper
• Rescue of Daudi cell HLA expression by transfection of the mouse beta 2- microglobulin gene

  1988cited by this paper
• Structure of the human class I histocompatibility antigen, HLA-A2

  1987cited by this paper
• Impaired assembly and transport of HLA‐A and ‐B antigens in a mutant TxB cell hybrid.

  1986cited by this paper
• Homozygous deletions that simultaneously eliminate expressions of class I and class II antigens of EBV-transformed B-lymphoblastoid cells. I. Reduced proliferative responses of autologous and allogeneic T cells to mutant cells that have decreased expression of class II antigens.

  1984cited by this paper
• Major histocompatibility antigens: the human (HLA-A, -B, -C) and murine (H-2K, H-2D) class I molecules.

  1981cited by this paper
• Cloning of influenza cDNA ino M13: the sequence of the RNA segment encoding the A/PR/8/34 matrix protein.

  1980cited by this paper
• Cell-free synthesis and membrane insertion of mouse H-2Dd histocompatibility antigen and beta 2-microglobulin.

  1979cited by this paper
• Cell-free synthesis and membrane insertion of mouse H-2Dd histocompatibility antigen and β2-microglobulin

  1979cited by this paper
• The genetic control of HLA-A and B antigens in somatic cell hybrids: requirement for beta2 microglobulin.

  1978cited by this paper

• HLA I immunopeptidome of synthetic long peptide pulsed human dendritic cells for therapeutic vaccine design

  2025cites this paper
• Enhanced mutanome analysis towards the induction of neoepitope-reactive T-cell responses for personalized immunotherapy of pancreatic cancer

  2025cites this paper
• Engineered HCMV‐infected APCs enable the identification of new immunodominant HLA‐restricted epitopes of anti‐HCMV T‐cell immunity

  2024cites this paper
• Preclinical evaluation of a novel CAR-T therapy utilizing a scFv antibody highly specific to MAGE-A4p230-239/HLA-A*02:01 complex.

  2024cites this paper
• Overcoming immune evasion from post-translational modification of a mutant KRAS epitope to achieve TCR-T cell-mediated antitumor activity

  2024cites this paper
• High-throughput, targeted MHC class I immunopeptidomics using a functional genetics screening platform

  2023cites this paper
• Targeting a neoantigen derived from a common TP53 mutation

  2021cites this paper
• Screening and identification of HLA-A2-restricted neoepitopes for immunotherapy of non-microsatellite instability-high colorectal cancer

  2021cites this paper
• Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy

  2021cites this paper
• Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry

  2018cites this paper
• HLA-A2-Restricted Epitopes Identified from MTA1 Could Elicit Antigen-Specific Cytotoxic T Lymphocyte Response

  2018cites this paper
• Identification of an HLA-A2-restricted CD147 epitope that can induce specific CTL cytotoxicity against drug resistant MCF-7/Adr cells.

  2018cites this paper
• Development of Peptide Vaccines in Dengue

  2018cites this paper
• Identification and characterization of enhancer agonist human cytotoxic T-cell epitopes of the human papillomavirus type 16 (HPV16) E6/E7.

  2017cites this paper
• Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1

  2017cites this paper
• Immunodominant Peptide Analogues CTL In Vitro by Selected Melan-A/MART-1 Enhanced Generation of Specific Tumor-Reactive

  2017cites this paper
• United States Patent Triebel

  2017cites this paper
• Identification of a naturally processed HLA-A*02:01-restricted CTL epitope from the human tumor-associated antigen Nectin-4

  2016cites this paper
• Phase I trial of thymidylate synthase poly-epitope peptide (TSPP) vaccine in advanced cancer patients

  2015cites this paper
• Isolierung und Charakterisierung allo-restringierter zytotoxischer T-Zellen mit spezifischer Reaktivität gegen HLA-A*0201-restringierte Peptidantigene der pädiatrischen akuten lymphatischen Leukämie

  2014cites this paper
• Identification of immunogenic MAGED4B peptides for vaccine development in oral cancer immunotherapy

  2014cites this paper
• Identification and characterization of a cytotoxic T-lymphocyte agonist epitope of brachyury, a transcription factor involved in epithelial to mesenchymal transition and metastasis

  2014influential citation
• Identification and characterization of agonist epitopes of the MUC1-C oncoprotein

  2014cites this paper
• Inhibition of Akt signaling promotes the generation of superior tumor-reactive T cells for adoptive immunotherapy.

  2014cites this paper
• Generation of multiple peptide cocktail-pulsed dendritic cells as a cancer vaccine.

  2014cites this paper
• Dendritic cell-based immunotherapy for colon cancer using an HLA-A*0201-restricted cytotoxic T-lymphocyte epitope from tumor-associated antigen 90K

  2013cites this paper
• Identification and Enhancement of HLA-A2.1-Restricted CTL Epitopes in a New Human Cancer Antigen-POTE

  2013cites this paper
• Purification and Characterization of a Naturally Processed Hepatitis B Virus Peptide Recognized by CD 8 1 Cytotoxic T Lymphocytes

  2013cites this paper
• Antibody-mimetic ligand selected by mRNA display targets DC-SIGN for dendritic cell-directed antigen delivery.

  2013cites this paper
• Identification and characterization of agonist epitopes of the MUC1-C oncoprotein

  2013cites this paper
• Minor Histocompatibility Antigen UTY as Target for Graft‐versus‐Leukemia and Graft‐versus‐Haematopoiesis in the Canine Model

  2013cites this paper
• hTERT, CD23 und CD229 als Tumorantigene bei der B-CLL

  2012influential citation
• Cross-immunizing potential of tumor MAGE-A epitopes recognized by HLA-A*02:01-restricted cytotoxic T lymphocytes.

  2012cites this paper
• The T-Cells’ Role in Antileukemic Reactions - Perspectives for Future Therapies’

  2012cites this paper
• Identification of novel HLA-A*0201-restricted epitopes from anterior gradient-2 as a tumor-associated antigen against colorectal cancer

  2012cites this paper
• Identification and immunogenicity of two new HLA-A*0201-restricted CD8+ T-cell epitopes on dengue NS1 protein.

  2012cites this paper
• EWS-FLI-1-Targeted Cytotoxic T-cell Killing of Multiple Tumor Types Belonging to the Ewing Sarcoma Family of Tumors

  2012cites this paper
• Discovery of T Cell Antigens by High-Throughput Screening of Synthetic Minigene Libraries

  2012cites this paper
• Evaluation of a non-viral vaccine in smallpox-vaccinated individuals and immunized HLA-transgenic mice.

  2012cites this paper
• Computational prediction and experimental assessment of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from neutral endopeptidase

  2012cites this paper
• Identification of HLA-A*0201-restricted cytotoxic T lymphocyte epitope from proliferating cell nuclear antigen

  2011cites this paper
• Targeting Human B-cell Malignancies through Ig Light Chain–Specific Cytotoxic T Lymphocytes

  2011cites this paper
• Identification of a new MAGE-A10 antigenic peptide presented by HLA-A*0201 on tumor cells

  2011cites this paper
• Identification of Two Novel HLA-A*0201-Restricted CTL Epitopes Derived from MAGE-A4

  2011cites this paper
• A lipopeptide based on the M2 and HA proteins of influenza A viruses induces protective antibody

  2010cites this paper
• Generation of autologous and allorestricted cytotoxic T cell clones directed against Ewing Tumor antigens

  2010cites this paper
• Defining novel targets for immunotheraphy of human cancer

  2010cites this paper
• Identification and modification of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from Ran antigen

  2009cites this paper
• New gene expressed in prostate: a potential target for T cell-mediated prostate cancer immunotherapy

  2009cites this paper
• Increased Frequency and Responsiveness of PSA-Specific T Cells After Allogeneic Hematopoetic Stem-Cell Transplantation

  2009cites this paper
• Cyclin D1 as a universally expressed mantle cell lymphoma-associated tumor antigen for immunotherapy

  2009cites this paper
• Identification of an HLA-A*0201-restrictive CTL epitope from MUC4 for applicable vaccine therapy

  2009cites this paper
• Generation of cytotoxicity against hepatitis delta virus genotypes and quasispecies by epitope modification.

  2009cites this paper
• HLA-A2-restricted cytotoxic T lymphocyte epitopes from human heparanase as novel targets for broad-spectrum tumor immunotherapy.

  2008cites this paper
• Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines

  2008cites this paper
• Significant effect of hepatitis C virus specific CTLs on viral clearance in patients with type C chronic hepatitis treated with antiviral agents

  2008cites this paper
• CD8+ T cells in type 1 diabetes.

  2008cites this paper
• Development of multi-epitope vaccines targeting wild-typesequence p53 peptides

  2008cites this paper
• Identification of a common HLA-A*0201-restricted epitope among SSX family members by mimicking altered peptide ligands strategy.

  2008cites this paper
• Analysis of the human cytomegalovirus pp65-directed T-cell response in healthy HLA-A2-positive individuals

  2008cites this paper
• Generation of cytotoxic T lymphocytes specific for B-cell acute lymphoblastic leukemia family-shared peptides derived from immunoglobulin heavy chain framework region.

  2007cites this paper
• Immunological Characterization of Respiratory Syncytial Virus N Protein Epitopes Recognized by Human Cytotoxic T Lymphocytes

  2007cites this paper
• Identification of cytotoxic T‐lymphocyte epitope(s) and its agonist epitope(s) of a novel target for vaccine therapy (PAGE4)

  2007cites this paper
• DKK 1 as a universal myeloma antigen DKK 1 IS A WIDELY EXPRESSED AND POTENT TUMOR-ASSOCIATED ANTIGEN IN MULTIPLE MYELOMA

  2007cites this paper
• Computational prediction and identification of HLA-A2.1-specific Ebola virus CTL epitopes.

  2007cites this paper
• Hemagglutinin protein is a primary target of the measles virus-specific HLA-A2-restricted CD8+ T cell response during measles and after vaccination.

  2007cites this paper
• Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.

  2007cites this paper
• Divergence in CD8+ T cell epitopes of HIV -1 as an immune escape mechanism

  2007cites this paper
• Identification and Characterization of ErbB-3-Binding Protein-1 as a Target for Immunotherapy1

  2007cites this paper
• Identification and Characterization of ErbB-3-Binding Protein-1 as a Target for Immunotherapy

  2007cites this paper
• Cytochrome P450IID6‐specific CD8 T cell immune responses mirror disease activity in autoimmune hepatitis type 2

  2007cites this paper
• Protective immunity provided by HLA-A2 epitopes for fusion and hemagglutinin proteins of measles virus.

  2006cites this paper
• Identification of a new HLA-A*0201-restricted cytotoxic T lymphocyte epitope from CML28

  2006cites this paper
• Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors.

  2006cites this paper
• Immunodominance and immunodomination: critical factors in developing effective CD8+ T-cell-based cancer vaccines.

  2006cites this paper
• An altered peptide ligand for naïve cytotoxic T lymphocyte epitope of TRP-2(180–188) enhanced immunogenicity

  2006cites this paper
• Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes.

  2006cites this paper
• In vitro expansion of Ag-specific T cells by HLA-A*0201-transfected K562 cells for immune monitoring.

  2006cites this paper
• T cells, dendritic cells and the human immune response to viruses and vaccines

  2006cites this paper
• The human minor histocompatibility antigen HA-1 : its processing, presentation and recognition

  2006cites this paper
• Identification of Novel HLA-A*0201–Restricted Epitopes in Recent-Onset Type 1 Diabetic Subjects and Antibody-Positive Relatives

  2006cites this paper
• Peptide from Human Carcinoembryonic Antigen Identification of an Enhancer Agonist Cytotoxic T Lymphocyte

  2006cites this paper
• Possible Therapeutic Vaccine Strategy against Human Immunodeficiency Virus Escape from Reverse Transcriptase Inhibitors Studied in HLA-A2 Transgenic Mice

  2006cites this paper
• Immunoinformatics Comes of Age

  2006cites this paper
• Identification of Novel Human CTL Epitopes and Their Agonist Epitopes of Mesothelin

  2005cites this paper
• Generation of RAGE‐1 and MAGE‐9 peptide‐specific cytotoxic T‐Lymphocyte lines for transfer in patients with renal cell carcinoma

  2005cites this paper
• Lassa Fever Virus Peptides Predicted by Computational Analysis Induce Epitope-Specific Cytotoxic-T-Lymphocyte Responses in HLA-A2.1 Transgenic Mice

  2005cites this paper
• Current approaches for the prediction and identification of CD8 T-cell epitopes in type 1 diabetes

  2005cites this paper
• Phase I/II study of immunotherapy with T-cell peptide epitopes in patients with stage IV melanoma

  2005cites this paper
• 5-fluorouracil-based chemotherapy enhances the antitumor activity of a thymidylate synthase-directed polyepitopic peptide vaccine.

  2005cites this paper
• The C Terminus of the Nucleoprotein of Influenza A Virus Delivers Antigens Transduced by Tat to the trans-Golgi Network and Promotes an Efficient Presentation through HLA Class I

  2005cites this paper
• CD23 is recognized as tumor-associated antigen (TAA) in B-CLL by CD8+ autologous T lymphocytes.

  2005cites this paper
• Immunotherapy and cancer vaccines in the management of breast cancer.

  2005cites this paper
• Identification of Novel Human CTL Epitopes and TheirAgonist Epitopes ofMesothelin

  2005cites this paper
• Identification of cancer-testis genes expressed by melanoma and soft tissue sarcoma using bioinformatics.

  2005cites this paper
• Cancer Immunity, Vol. 5, p. 2 (1 February 2005)

  2005cites this paper
• Differential CTLs specific for prostate-specific antigen in healthy donors and patients with prostate cancer.

  2005cites this paper
• Protection against Lethal Vaccinia Virus Challenge in HLA-A2 Transgenic Mice by Immunization with a Single CD8+ T-Cell Peptide Epitope of Vaccinia and Variola Viruses

  2004cites this paper
• HLA-A2-Restricted CD8+-Cytotoxic-T-Cell Responses to Novel Epitopes in Mycobacterium tuberculosis Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase

  2004cites this paper
• A Human Cytotoxic T-Lymphocyte Epitope and Its Agonist Epitope from the Nonvariable Number of Tandem Repeat Sequence of MUC-1

  2004cites this paper