Papulacandins, a new family of antibiotics with antifungal activity, I. Fermentation, isolation, chemical and biological characterization of papulacandins A, B, C, D and E.

No abstract is available for this paper.

• Publication year

  1977

• Venue

  Journal of antibiotics (Tokyo. 1968)

• Publication date

  1977-04-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.7164/ANTIBIOTICS.30.289PMID 324958
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Papulacandin B: an inhibitor of glucan synthesis in yeast spheroplasts.

  1979cited by this paper
• Zur Struktur von Papulacandin B, einem neuen antifungischen Antibiotikum. Vorläufige Mitteilung

  1977cited by this paper
• The Structure of Tunicamycin

  1977cited by this paper
• Struktur des cyclopeptid-antibiotikums sl 7810 (= echinocandinb)

  1976cited by this paper
• Stoffwechselprodukte von Mikroorganismen. 160. Mitteilung. Conocandin, ein fungistatisches Antibiotikum aus Hormococcus conorum (SACC. et ROUM.) ROBACK

  1976cited by this paper
• [Metabolites from microorganisms. Conocandin, a new fungi-static antibiotic (author's transl)].

  1976cited by this paper
• Letter: Gnididin, gniditrin, and gnidicin, novel potent antileukemic diterpenoid esters from Gnidia lamprantha.

  1975cited by this paper
• Stoffwechselprodukte von Mikroorganismen 143. Mitteilung. Echinocandin B, ein neuartiges Polypeptid‐Antibioticum aus Aspergillus nidulans var. echinulatus: Isolierung und Bausteine

  1974cited by this paper
• Chemistry and Biology of the Polyene Macrolide Antibiotics

  1973cited by this paper
• Miconazole, a broad-spectrum antimycotic agent with antibacterial activity.

  1972cited by this paper
• Protonenresonanzspektroskopische Untersuchungen von Galaktose‐Derivaten

  1968cited by this paper
• THE POLYENE ANTIFUNGAL ANTIBIOTICS.

  1963cited by this paper

• New sordarialean lineage Garciamycella chlamydospora (Sordariales, Schizotheciaceae) produces rare antifungal papulacandins

  2026cites this paper
• Untargeted GC–MS metabolic profiling of Eurotium chevalieri AUMC 16390 (PX498623) reveals a putative steroidal metabolite with antibacterial and anti-inflammatory potential

  2026cites this paper
• Concise Biosynthesis of Antifungal Papulacandins.

  2025cites this paper
• Bioactive Spirocyclic C‐Arylglycosides From the Fungal–Fungal Co‐Culture of Pestalotiopsis sp. and Nigrospora sp.

  2025cites this paper
• A Strategy for the Development of New Antimycotics Acting on the Cell Wall and Cell Membrane of Fungi

  2025cites this paper
• Innovations in Antifungal Drug Discovery among Cell Envelope Synthesis Enzymes through Structural Insights

  2024cites this paper
• Heteryunine A, an amidated tryptophan-catechin-spiroketal hybrid with antifibrotic activity from Heterosmilax yunnanensis.

  2024cites this paper
• Pestiorosins A–F, New Papulacandins Isolated from the Fungus Pestalotiopsis rosea YNJ21

  2024cites this paper
• On the origin of the electronic and magnetic circular dichroism of naphthyl C-glycosides: Anomeric configuration.

  2023cites this paper
• Synthesis of Gluco‐Alkynones via a Carbonylative Coupling Reaction Using 1‐Iodoglucal

  2023cites this paper
• Advances in the Synthesis of Natural Products and Medicinally Relevant Molecules from Glycals

  2022cites this paper
• A Water-Soluble Antibiotic in Rhubarb Stalk Shows an Unusual Pattern of Multiple Zones of Inhibition and Preferentially Kills Slow-Growing Bacteria

  2021cites this paper
• Advances in Pd-catalyzed C–C bond formation in carbohydrates and their applications in the synthesis of natural products and medicinally relevant molecules

  2021cites this paper
• Fungal resources: Current utilization, future prospects, and challenges

  2021cites this paper
• Natural products targeting the synthesis of β(1,3)-D-glucan and chitin of the fungal cell wall. Existing drugs and recent findings.

  2021cites this paper
• Fungal glycosides: Structure and biological function

  2021cites this paper
• Synthesis of novel papulacandin D analogs and evaluation of their antifungal potential

  2020cites this paper
• Antimicrobial Peptides: a New Frontier in Antifungal Therapy

  2020cites this paper
• Recent Progress in the Discovery of Antifungal Agents Targeting the Cell Wall.

  2020cites this paper
• Spiroketal Phthalane C-Glycosides: Synthesis of Papulacandins and SGLT2 Inhibitors

  2019cites this paper
• Cell Wall-Modifying Antifungal Drugs.

  2019cites this paper
• The antifungal activity and mechanisms of action of quantified extracts from berries, leaves and roots of Phytolacca tetramera.

  2019cites this paper
• Role of Antifungal Drugs in Combating Invasive Fungal Diseases

  2019cites this paper
• The fungal cell wall as a target for the development of new antifungal therapies.

  2019cites this paper
• Pestiocandin, a new papulacandin class antibiotic isolated from Pestalotiopsis humus

  2018cites this paper
• IN-SILICO STUDIES OF SOME NATURAL, SYNTHETIC AND SEMI-SYNTHETIC ANTIFUNGAL DRUGS FOR THEIR MULTI-TARGETING NATURE

  2018cites this paper
• Stereoretentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study.

  2018cites this paper
• Potentiality and Synthesis of O- and N-Heterocycles: Pd-Catalyzed Cyclocarbonylative Sonogashira Coupling as a Valuable Route to Phthalans, Isochromans, and Isoindolines

  2017cites this paper
• De novo Asymmetric Synthesis of Carbohydrate Natural Products

  2017cites this paper
• Total Synthesis of Aryl C-Glycoside Natural Products: Strategies and Tactics.

  2017cites this paper
• Anti-Candida albicans natural products, sources of new antifungal drugs: A review.

  2017cites this paper
• Fungal Metabolites for the Control of Biofilm Infections

  2016cites this paper
• Enantioselective Allylation of β‐Haloacrylaldehydes: Formal Total Syntheses of Pteroenone and Antillatoxin

  2016cites this paper
• Tricking Arthrinium malaysianum into Producing Industrially Important Enzymes Under 2-Deoxy D-Glucose Treatment

  2016cites this paper
• Antifungal Agents That Target Fungal Cell Wall Components : A Review

  2015cites this paper
• Evolution of Chemical Diversity in Echinocandin Lipopeptide Antifungal Metabolites

  2015cites this paper
• Organo-zinc Promoted Diastereoselective C-Arylation of 1,2-Anhydrosugars from Arylboronic Acids.

  2015cites this paper
• Antimicrobial Compounds

  2014cites this paper
• New Cell Wall-Affecting Antifungal Antibiotics

  2014cites this paper
• De novo asymmetric synthesis of the pyranoses: From monosaccharides to oligosaccharides.

  2014cites this paper
• Cross-coupling reaction of saccharide-based alkenyl boronic acids with aryl halides: the synthesis of bergenin.

  2014cites this paper
• Phthalides and phthalans: synthetic methodologies and their applications in the total synthesis.

  2014cites this paper
• A novel echinocandin MIG0310 with anticandida activity from newly isolated Fusarium sp. strain MS‐R1

  2014cites this paper
• Genome dynamics and virulence in the human pathogen Candida glabrata

  2014cites this paper
• Lipase-catalyzed asymmetric acylation in the chemoenzymatic synthesis of furan-based alcohols

  2013cites this paper
• Undressing the fungal cell wall/cell membrane--the antifungal drug targets.

  2013cites this paper
• De novo asymmetric synthesis of the pyranoses: from monosaccharides to oligosaccharides.

  2013cites this paper
• Synthesis of O-spiro-C-aryl glycosides using organocatalysis.

  2012cites this paper
• Fungal endophytes: a potential source of antifungal compounds.

  2012influential citation
• Chapter 4 - Total Synthesis of Papulacandin D

  2012cites this paper
• Synthesis and antifungal properties of papulacandin derivatives

  2012cites this paper
• Emerging Targets in Antibacterial and Antifungal Chemotherapy

  2012influential citation
• Non-β-Lactam Antibiotics

  2011cites this paper
• Catalytic enantioselective allylation of carbonyl compounds and imines.

  2011cites this paper
• Total Synthesis of (+)-Papulacandin D.

  2010cites this paper
• Discovery and characterization of ß-1,6-glucan inhibitors

  2010cites this paper
• Isolation, biological activity and synthesis of benzannulated spiroketal natural products.

  2010cites this paper
• Echinocandins: Exploring Susceptibility and Resistance

  2009cites this paper
• Biosynthetic Enzymes for (1-3)-β-Glucans, (1-3;1-6)-β-Glucans from Yeasts: Biochemical Properties and Molecular Biology

  2009cites this paper
• Discovery of a Small-Molecule Inhibitor of (cid:2) -1,6-Glucan Synthesis (cid:1)

  2009cites this paper
• The hetero-Diels-Alder approach to spiroketals.

  2009cites this paper
• Cell wall of Aspergillus fumigatus: a dynamic structure.

  2009cites this paper
• Discovery of a Small-Molecule Inhibitor of β-1,6-Glucan Synthesis

  2008cites this paper
• Novel Antifungal Antibiotic from Myrothecium cinctum No . 002 I . Taxonomy , Fermentation , Isolation and Physico-chemical Properties

  2008cites this paper
• Lysis of growing cells ofSaccharomyces cerevisiae induced by papulacandin B

  2008cites this paper
• Total synthesis of papulacandin D.

  2007cites this paper
• The synthesis and biological activity of novel spiro-isoxazoline C-disaccharides based on 1,3-dipolar cycloaddition of exo-glycals and sugar nitrile oxides

  2007cites this paper
• BU-4794F, A NEW j8-l,3-GLUCAN SYNTHASE INHIBITOR

  2006cites this paper
• Antifungal antibiotics from potential biocontrol microorganisms

  2006cites this paper
• Functional Networks Involved in Cell Wall Biosynthesis and the Isoprenoid Pathway in the Yeast Saccharomyces cerevisiae

  2006cites this paper
• The Fungal Cell Wall

  2006cites this paper
• Palladium-catalyzed cross-coupling reactions of silanolates: a paradigm shift in silicon-based cross-coupling reactions.

  2006cites this paper
• FR 207944 , an Antifungal Antibiotic from Chaetomium sp . No . 217 I . Taxonomy , Fermentation , and Biological Properties

  2005cites this paper
• De novo synthesis of a galacto-papulacandin moiety via an iterative dihydroxylation strategy

  2005cites this paper
• Efficient Synthesis of Isobenzofuran-1(3H)-ones (Phthalides) and Selected Biological Evaluations

  2005cites this paper
• FR207944, an Antifungal Antibiotic from Chaetomium sp. No. 217 I. Taxonomy, Fermentation, and Biological Properties

  2005cites this paper
• Astonishing diversity of natural surfactants: 2. Polyether glycosidic ionophores and macrocyclic glycosides

  2005cites this paper
• FR227244, a novel antifungal antibiotic from Myrothecium cinctum No. 002 Taxonomy, fermentation, isolation and physico-chemical properties.

  2004cites this paper
• In vitro conidial germination in Arthrinium aureum and Arthrinium phaeospermum

  2004cites this paper
• Fungal b (1,3)- D -glucan synthesis

  2004cites this paper
• Microbial natural products as a source of antifungals.

  2003cites this paper
• Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis.

  2003cites this paper
• F-10748 A1, A2, B1, B2, C1, C2, D1 and D2, novel papulacandins.

  2002cites this paper
• In vitro Inhibition of 1,3-β-Glucan Synthase by Glycolipids from Convolvulaceous Species

  2002cites this paper
• A novel approach to the regioselective acylation of spirocyclic C-glucoside of papulacandins

  2002cites this paper
• In vitro inhibition of 1,3-beta-glucan synthase by glycolipids from convolvulaceous species.

  2002cites this paper
• Fungal β(1,3)-d-glucan synthesis

  2001cites this paper
• Vasorelaxant effects of pramanicin, an anti-fungal agent: selective action on endothelial cells.

  2001cites this paper
• Les nouveaux antifongiques et leur straégie de recherche

  2001cites this paper
• Organotransition metal modified sugars: Part 22. Direct metalation of glycals: short and efficient routes to diversely protected stannylated glycals

  2001cites this paper
• A convenient and highly regio and stereoselective method for the synthesis of (E)-3-alkylidene isobenzofuran-1(3H)-ones (phthalides)

  2001cites this paper
• Fungal beta(1,3)-D-glucan synthesis.

  2001cites this paper
• Effect of the raw extracts of Arthrinium strains (Hyphomycetes, Dematiaceae) on the growth of some deleterious fungi in poultry feed.

  2001cites this paper
• Glucan synthase inhibitors as antifungal agents.

  2001cites this paper
• Sharpless asymmetric dihydroxylation of 5-aryl-2-vinylfurans: application to the synthesis of the spiroketal moiety of papulacandin D.

  2000cites this paper
• Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors

  2000cites this paper
• Enantioselective synthesis of the papulacandin ring system: conversion of the mannose diastereoisomer into a glucose stereoisomer.

  2000cites this paper
• FR901469, a novel antifungal antibiotic from an unidentified fungus No.11243. II. In vitro and in vivo activities.

  2000cites this paper
• FR901469, a novel antifungal antibiotic from an unidentified fungus No.11243. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological properties.

  2000cites this paper
• Reductive aromatization of quinols: synthesis of the C-arylglycoside nucleus of the papulacandins and chaetiacandin.

  2000cites this paper