Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1995-04-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.92.8.3541PMID 7536937PMCID PMC42203
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice.

  1994cited by this paper
• Trypanosoma cruzi: characterization of two recombinant antigens with potential application in the diagnosis of Chagas' disease.

  1993cited by this paper
• Natural mouse IgG reacts with self antigens including molecules involved in the immune response

  1992cited by this paper
• Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi

  1992cited by this paper
• A workbench for multiple alignment construction and analysis

  1991cited by this paper
• Myosin-induced acute myocarditis is a T cell-mediated disease.

  1991cited by this paper
• Molecular mimicry by Trypanosoma cruzi: the F1-160 epitope that mimics mammalian nerve can be mapped to a 12-amino acid peptide.

  1991cited by this paper
• Trypanosoma cruzi: antibodies to a MAP-like protein in chronic Chagas' disease cross-react with mammalian cytoskeleton.

  1991cited by this paper
• Trypanocidal nitroarene treatment of experimental Trypanosoma cruzi infection does not prevent progression of chronic-phase heart lesions in rabbits.

  1990cited by this paper
• Physical activity, opportunity for reinfection, and sibling history of heart disease as risk factors for Chagas' cardiopathy.

  1990cited by this paper
• Autoimmunity in Chagas' disease: specific inhibition of reactivity of CD4+ T cells against myosin in mice chronically infected with Trypanosoma cruzi

  1989cited by this paper
• Identification of major Trypanosoma cruzi antigenic determinants in chronic Chagas' heart disease.

  1989cited by this paper
• Human monoclonal antibodies reactive with antigens of the group A Streptococcus and human heart.

  1988cited by this paper
• Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to Coxsackievirus B3-induced myocarditis.

  1987cited by this paper
• Strategies for epitope analysis using peptide synthesis.

  1987cited by this paper
• The Role of active myocarditis in the development of heart failure in chronic chagas' disease: A study based on endomyocardial biopsies

  1987cited by this paper
• Cardiac myosin induces myocarditis in genetically predisposed mice.

  1987cited by this paper
• Sequence of myosin-crossreactive epitopes of streptococcal M protein

  1986cited by this paper
• General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids.

  1985cited by this paper
• Myosin Types in the Human Heart: An Immunofluorescence Study of Normal and Hypertrophied Atrial and Ventricular Myocardium

  1984cited by this paper
• Heterophil nature of EVI antibody in Trypanosoma cruzi infection.

  1983cited by this paper
• Preparation of myosin and its subfragments from rabbit skeletal muscle.

  1982cited by this paper
• Cell surface antigens of Trypanosoma cruzi: possible correlation with the interiorization process in mammalian cells.

  1982cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• The immunology of experimental Chagas' disease. IV. Production of lesions in rabbits similar to those of chronic Chagas' disease in man.

  1975cited by this paper
• Chagasic Cardiopathy: Demonstration of a Serum Gamma Globulin Factor Which Reacts with Endocardium and Vascular Structures

  1974cited by this paper
• Heterogeneity and structure of antibody-combining sites.

  1970cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Unraveling the Missing Pieces: Exploring the Gaps in Understanding Chagas Cardiomyopathy

  2024cites this paper
• An idealized human cardiomyocyte finite element model for studying the interaction between the cross-bridge state and cell mechanical response *

  2023influential citation
• A safe, effective, and reliable vaccine against Chagas disease should be described!

  2022cites this paper
• 34 Chagas Heart Disease

  2022cites this paper
• Functional antibodies against G-protein coupled receptors in Beagle dogs infected with two different strains of Trypanosoma cruzi

  2022cites this paper
• Prediction of molecular mimicry between proteins from Trypanosoma sp. and human antigens associated with systemic lupus erythematosus.

  2022cites this paper
• A refined genome phage display methodology delineates the human antibody response in patients with Chagas disease

  2021cites this paper
• LEVELS OF ANTI-B13 ANTIBODIES OVER TIME IN A COHORT OF CHRONIC INFECTED BY TRYPANOSOMA CRUZI. ITS RELATIONSHIP WITH SPECIFIC TREATMENT AND CLINICAL STATUS.

  2021cites this paper
• Systemic cytokines, chemokines and growth factors reveal specific and shared immunological characteristics in infectious cardiomyopathies.

  2021cites this paper
• The Tryp and the Pendulum

  2021cites this paper
• Benznidazole decreases the risk of chronic Chagas disease progression and cardiovascular events: A long-term follow up study

  2020cites this paper
• Cardiac magnetic resonance imaging in Chagas’ disease: a parallel with electrophysiologic studies

  2020cites this paper
• Glycemic Control, Cardiac Autoimmunity, and Long-Term Risk of Cardiovascular Disease in Type 1 Diabetes Mellitus: A DCCT/EDIC Cohort–Based Study

  2019cites this paper
• The senseless orphanage of Chagas disease

  2019cites this paper
• Autoimmunity in Chronic Chagas Disease: A Road of Multiple Pathways to Cardiomyopathy?

  2018cites this paper
• Systems Biology Reveals Relevant Gaps in Fc-γR Expression, Impaired Regulatory Cytokine Microenvironment Interfaced With Anti-Trypanosoma cruzi IgG Reactivity in Cardiac Chagas Disease Patients

  2018cites this paper
• MyD88 activation in cardiomyocytes contributes to the heart immune response to acute Trypanosoma cruzi infection with no effect on local parasite control

  2018cites this paper
• Archaea Symbiont of T. cruzi Infection May Explain Heart Failure in Chagas Disease

  2018cites this paper
• Divergent Roles of Antiself Antibodies during Infection.

  2018cites this paper
• Chapter 23 – Chagas Cardiomyopathy

  2017cites this paper
• IFN-γ versus IL-17: A Battle During Cardiac Autoimmunity Evolution

  2017cites this paper
• Combined analysis of cross‐reacting antibodies anti‐β1AR and anti‐B13 in advanced stages of Chagas heart disease

  2016influential citation
• Presencia en exovesículas y su papel en la enfermedad de chagas de las regiones N- Y C- terminal de las proteínas MASPs de Trypanosoma cruzi

  2016cites this paper
• Aspectos imunológicos da infecção por Trypanosoma cruzi: persistência do parasita e autoimunidade

  2016cites this paper
• The Role of Dystrophin Loss in the Trypanosoma cruzi Infection

  2016cites this paper
• Plasma IgG autoantibody against actin‐related protein 3 in liver fluke Opisthorchis viverrini infection

  2015cites this paper
• Myocardial tissue characterization in Chagas’ heart disease by cardiovascular magnetic resonance

  2015cites this paper
• Arrhythmias in chagasic cardiomyopathy.

  2015cites this paper
• Avaliação da inflamação miocárdica na doença de Chagas por ressonância magnética cardiovascular

  2015cites this paper
• Biomarkers for cardiovascular risk assessment in autoimmune diseases

  2015cites this paper
• Genetics and Vaccines in the Era of Personalized Medicine

  2015cites this paper
• Interações imunoendócrinas na migração de linfócitos na doença de chagas humana crônicarelação com a cardiopatia

  2015cites this paper
• Molecular mechanisms of myocarditis caused by Trypanosoma cruzi

  2015cites this paper
• Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead.

  2015cites this paper
• Molecular Mimicry and Autoimmunity

  2015cites this paper
• Chagas Disease: Still Many Unsolved Issues

  2014cites this paper
• Trypanosoma cruzi Infection and Host Lipid Metabolism

  2014cites this paper
• Perfil de expressão de microRNAS no miocárdio na infecção aguda pelo Trypanosoma cruzi em camundongos

  2014cites this paper
• Avaliação do metabolismo e atividade inflamatória nas diversas formas evolutivas da doença de Chagas: correlação com disfunção autonômica

  2013cites this paper
• Troponin T autoantibodies correlate with chronic cardiomyopathy in human Chagas disease

  2013cites this paper
• Ergosterol Biosynthesis for the Specific Treatment of Chagas Disease: From Basic Science to Clinical Trials

  2013cites this paper
• Assessment of cross-reactive host-pathogen antibodies in patients with different stages of chronic Chagas disease.

  2013cites this paper
• MINISTÉRIO DA EDUCAÇÃO UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE PERFIL DE IMUNOGLOBULINAS E CORRELAÇÃO DE AUTOANTICORPOS COM A OCORRÊNCIA DE DIVERSAS FORMAS CLÍNICAS EM PACIENTES CHAGÁSICOS CRÔNICOS

  2013cites this paper
• A infecção murina pelo Trypanosoma cruzi clone Sylvio X10/4: envolvimento do sistema imune no controle da parasitemia

  2013cites this paper
• Valoración de anticuerpos con reactividad cruzada patógeno-huésped en pacientes con diferentes estadios de cardiopatía chagásica crónica

  2013cites this paper
• Evaluating Chagas disease progression and cure through blood-derived biomarkers: a systematic review

  2013cites this paper
• Avaliação da atividade anti-Trypanosoma cruzi do derivado triazólico Ravuconazol utilizando o cão como modelo experimental.

  2013cites this paper
• Biologic and Genetics Aspects of Chagas Disease at Endemic Areas

  2012cites this paper
• Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

  2012cites this paper
• Determinação das concentrações séricas da lectina ligante de manose (MBL) e da proteína C-Reativa (CRP) em portadores da Doença de Chagas crônica

  2012cites this paper
• Enfermedades de chagas crónica: estrés oxidativo y miocarditis chagásica asociada a la persistencia parasitaria

  2012cites this paper
• Pathogenesis of Chagas disease: time to move on.

  2012cites this paper
• Autoreactive antibodies raised by self derived de novo peptides can identify unrelated antigens on protein microarrays. Are autoantibodies really autoantibodies?

  2012cites this paper
• A infecção experimental pelo Trypanosoma cruzi agrava o desenvolvimento de lesões ateroscleróticas em camundongos apoE

  2012cites this paper
• Trypanosoma cruzi in the Chicken Model: Chagas-Like Heart Disease in the Absence of Parasitism

  2011cites this paper
• Pathogenesis of Chagas' Disease: Parasite Persistence and Autoimmunity

  2011cites this paper
• Enfermedad de chagas crónica. Reacción de polimerasa en cadena (PCR) aplicada al diagnóstico y evaluación quimioterapéutica

  2011cites this paper
• Characterization of an Immunodominant Antigenic Epitope from Trypanosoma cruzi as a Biomarker of Chronic Chagas' Disease Pathology

  2011cites this paper
• Myocardial gene and protein expression profiles after autoimmune injury in Chagas' disease cardiomyopathy.

  2011cites this paper
• Chapter 6 – Autoimmunity

  2011cites this paper
• New diagnostic serum biomarkers for Chagas disease.

  2011cites this paper
• IL-17 Produced during Trypanosoma cruzi Infection Plays a Central Role in Regulating Parasite-Induced Myocarditis

  2010cites this paper
• Impacto da superexpressão da proteína Prion Celular sobre o sistema imune correlação com maior susceptibilidade à infecção experimental pelo Trypanosoma cruzi

  2010cites this paper
• New insights in Chagas disease treatment

  2010cites this paper
• Current and developing therapeutic agents in the treatment of Chagas disease

  2010cites this paper
• Chagas cardiomyopathy--where do we stand after a hundred years?

  2010cites this paper
• Cardiac Involvement with Parasitic Infections

  2010cites this paper
• Use of nanorobots in heart transplantation

  2010cites this paper
• Vaccines and autoimmune diseases of the adult.

  2010cites this paper
• Pathological Consequences of Host Response to Parasites

  2010cites this paper
• Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches.

  2010cites this paper
• Narrowed lumen of the right coronary artery in chronic Chagasic patients is associated with ischemic lesions of segmental thinnings of ventricles.

  2010cites this paper
• Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease.

  2009cites this paper
• Chapter 69 – American Trypanosomiasis

  2009cites this paper
• Ergosterol biosynthesis and drug development for Chagas disease.

  2009cites this paper
• Trypanosoma cruzi: parasite antigens sequestered in heart interstitial dendritic cells are related to persisting myocarditis in benznidazole-treated mice.

  2009cites this paper
• Do Archaea and bacteria co-infection have a role in the pathogenesis of chronic chagasic cardiopathy?

  2009cites this paper
• The role of parasite persistence in pathogenesis of Chagas heart disease

  2009cites this paper
• cDNA cloning and partial characterization of amastigote specific surface protein from Trypanosoma cruzi.

  2009cites this paper
• Therapy, diagnosis and prognosis of chronic Chagas disease: insight gained in Argentina.

  2009cites this paper
• The role of infections in autoimmune disease

  2009cites this paper
• Neuropathy of Gastrointestinal Chagas’ Disease: Immune Response to Myelin Antigens

  2008cites this paper
• Role of autoantibodies in the physiopathology of Chagas' disease.

  2008cites this paper
• Expressão de citocinas inflamatórias e quimiocinas no tecido cardíaco de pacientes com Cardiomiopatia Chagásica Crônica

  2008cites this paper
• Invasive and noninvasive correlations of B-type natriuretic peptide in patients with heart failure due to Chagas cardiomyopathy.

  2008cites this paper
• Fas/Fas-L expression, apoptosis and low proliferative response are associated with heart failure in patients with chronic Chagas' disease.

  2008cites this paper
• Chagas heart disease pathogenesis: one mechanism or many?

  2008cites this paper
• Trypanosoma cruzi: the role of PGE2 in immune response during the acute phase of experimental infection.

  2008cites this paper
• Chagas disease cardiomyopathy: current concepts of an old disease.

  2008cites this paper
• Pathogenesis of Chronic Chagas Heart Disease

  2007cites this paper
• Modulation of Autoimmunity by Treatment of an Infectious Disease

  2007cites this paper
• Cytokines and cell adhesion receptors in the regulation of immunity to Trypanosoma cruzi.

  2007cites this paper
• Experimental model of autoimmune myosin-induced myocardium injury

  2007cites this paper
• Etiological treatment of chronic Chagas disease: neglected ‘evidence’ by evidence-based medicine

  2007cites this paper
• Role of Trypanosoma cruzi Autoreactive T Cells in the Generation of Cardiac Pathology

  2007cites this paper
• Treating the Children of Bolivia Infected with Chagas Disease: A Cost-Benefit Analysis

  2006cites this paper
• Characterization of cardiopulmonary function and cardiac muscarinic and adrenergic receptor density adaptation in C57BL/6 mice with chronic Trypanosoma cruzi infection

  2006cites this paper
• Induction of cardiac autoimmunity in Chagas heart disease: A case for molecular mimicry

  2006cites this paper
• [No association between persistence of the parasite and electrocardiographic evolution in treated patients with Chagas disease].

  2005cites this paper
• Molecular mimicry : infection-inducing autoimmune disease

  2005cites this paper