Inhibition of CX3CL1 (Fractalkine) Improves Experimental Autoimmune Myositis in SJL/J Mice1

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Immunology

• Publication date

  2005-11-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.4049/jimmunol.175.10.6987PMID 16272359
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• [Polymyositis, dermatomyositis and inclusion body myositis, nosological aspects].

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• The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.

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• Differential expression of chemokines in inflammatory myopathies

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• Muscle biopsy findings in inflammatory myopathies.

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• The Proinflammatory CD14+CD16+DR++ Monocytes Are a Major Source of TNF1

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• FK506 suppressed the inflammatory change of EAM in SJL/J mice.

  2001cited by this paper
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• Myosin-induced autoimmune polymyositis in the rat.

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• Polymyositis, dermatomyositis and inclusion-body myositis.

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• Experimental autoimmune myositis in SJL/J mice.

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• Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method

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