Management of hyperbilirubinemia and prevention of kernicterus in 20 patients with Crigler-Najjar disease

No abstract is available for this paper.

• Publication year

  2006

• Venue

  European Journal of Pediatrics

• Publication date

  2006-01-25

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00431-005-0055-2PMID 16435131
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Determination of the vacant amount of high-affinity bilirubin binding site on serum albumin.

  2009cited by this paper
• Lessons from the past

  2005cited by this paper
• Risk management of severe neonatal hyperbilirubinemia to prevent kernicterus.

  2005cited by this paper
• Lessons from the past.

  2005cited by this paper
• Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function.

  2004cited by this paper
• Chapter 121 – Bilirubin Metabolism and Toxicity in the Newborn

  2004cited by this paper
• Phototherapy: current methods and future directions.

  2004cited by this paper
• Bilirubin-albumin binding and neonatal jaundice.

  2004cited by this paper
• Treatment of Crigler-Najjar type 1 disease: relevance of early liver transplantation.

  2003cited by this paper
• Unbound bilirubin in a term newborn with kernicterus.

  2003cited by this paper
• Overview of pediatric liver transplantation.

  2003cited by this paper
• Fetal and Neonatal Physiology

  2003cited by this paper
• Greenfield's Neuropathology

  2002cited by this paper
• System-based approach to management of neonatal jaundice and prevention of kernicterus.

  2002cited by this paper
• The Metabolic and Molecular Bases of Inherited Disease

  2001cited by this paper
• Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets.

  2001cited by this paper
• The Blood–Brain Barrier and Bilirubin Encephalopathy

  2000cited by this paper
• Predictive Ability of a Predischarge Hour-specific Serum Bilirubin for Subsequent Significant Hyperbilirubinemia in Healthy Term and Near-term Newborns

  1999cited by this paper
• Jaundice and disorders of bilirubin metabolism

  1998cited by this paper
• Neurologic Perspectives of Crigler-Najjar Syndrome Type I

  1998cited by this paper
• Pediatricians' awareness of and attitudes about four clinical practice guidelines.

  1998cited by this paper
• Practice Patterns in Neonatal Hyperbilirubinemia

  1998cited by this paper
• Crigler-Najjar syndrome in Saudi Arabia.

  1998cited by this paper
• Lack of deafness in Crigler-Najjar syndrome type 1: a patient survey.

  1997cited by this paper
• Kernicterus in an adult who is heterozygous for Crigler-Najjar syndrome and homozygous for Gilbert-type genetic defect.

  1997cited by this paper
• Decreased mortality from technical failure improves results in pediatric liver transplantation.

  1996cited by this paper
• Current therapy for Crigler‐Najjar syndrome type 1: Report of a world registry

  1996cited by this paper
• Does ibuprofen affect bilirubin-albumin binding in newborn infant serum?

  1996cited by this paper
• Mapping of the consequences of bilirubin exposure in the immature rat: local cerebral metabolic rates for glucose during moderate and severe hyperbilirubinemia.

  1995cited by this paper
• Ceftriaxone-bilirubin-albumin interactions in the neonate: An in vivo study

  1993cited by this paper
• Home phototherapy: use and attitudes among community pediatricians.

  1993cited by this paper
• Bilirubin Displacing Effect of Drugs Used in Neonatology

  1991cited by this paper
• Effect of drug combinations on bilirubin-albumin binding.

  1991cited by this paper
• Increase of plasma nonesterified fatty acid concentration and decrease of albumin binding affinity after intravenous injection of glycocholate-lecithin mixed micelles.

  1990cited by this paper
• Displacement of bilirubin from adult and newborn serum albumin by a drug and fatty acid.

  1989cited by this paper
• In vitro displacement of bilirubin by antibiotics and 2-hydroxybenzoylglycine in newborns

  1988cited by this paper
• PHOTOTHERAPY FOR NEONATAL JAUNDICE

  1988cited by this paper
• Effect of penicillins on bilirubin-albumin binding.

  1988cited by this paper
• Effect of cephalosporins on bilirubin-albumin binding.

  1988cited by this paper
• Ceftriaxone effect on bilirubin-albumin binding.

  1987cited by this paper
• Neonatal Bilirubin Toxicity

  1987cited by this paper
• Binding effect of albumin on uptake of bilirubin by brain.

  1987cited by this paper
• Albumin binding of anti-inflammatory drugs. Utility of a site-oriented versus a stoichiometric analysis.

  1984cited by this paper
• Influence of free fatty acids and glucose infusion on serum bilirubin and bilirubin binding to albumin: clinical implications.

  1983cited by this paper
• Bilirubin-displacing effect of furosemide and sulfisoxazole. An in vitro and in vivo study in neonatal serum.

  1983cited by this paper
• Effect of lactate, pyruvate, acetone, acetoacetate, and beta-hydroxybutyrate on albumin binding of bilirubin.

  1983cited by this paper
• Drug-induced displacement of bilirubin from albumin in the newborn.

  1983cited by this paper
• Bilirubin-displacing effect of ampicillin, indomethacin, chlorpromazine, gentamicin, and parabens in vitro and in newborn infants.

  1983cited by this paper
• COMPARISON BETWEEN TWO PREPARATIONS OF HUMAN SERUM ALBUMIN IN TREATMENT OF NEONATAL HYPERBILIRUBINAEMIA

  1982cited by this paper
• Albumin reserve for binding of bilirubin in maternal and cord serum under treatment with sulphasalazine.

  1981cited by this paper
• Bilirubin. Solubility and interaction with albumin and phospholipid.

  1979influential reference
• Displacement of Bilirubin from Albumin by Indomethacin

  1978cited by this paper
• Binding of bilirubin and long-chain fatty acids to human serum albumin with general remarks on displacement of firmly bound ligands.

  1977cited by this paper
• The effect of paraben preservatives on albumin binding of bilirubin.

  1976cited by this paper
• ANTITHROMBIN ACTIVITY IN HOMOCYSTINURIA

  1975cited by this paper
• TOXIC EFFECTS IN THE GUNN RAT OF COMBINED TREATMENT WITH BILIRUBIN AND OROTIC ACID

  1972cited by this paper
• THE FUTURE DEMISE OF EXCHANGE TRANSFUSIONS FOR NEONATAL HYPERBILIRUBINEMIA

  1968cited by this paper
• INFLUENCE OF LIGHT ON THE HYPERBILIRUBINÆMIA OF INFANTS

  1958cited by this paper
• Influence of light on the hyperbilirubinaemia of infants.

  1958cited by this paper
• A difference in mortality rate and incidence of kernicterus among premature infants allotted to two prophylactic antibacterial regimens.

  1956cited by this paper
• Congenital familial nonhemolytic jaundice with kernicterus.

  1952influential reference
• The Farnsworth-Munsell 100-Hue and Dichotomous Tests for Color Vision*

  1943cited by this paper
• Investigations on the Intrinsic Properties of the Color Domain

  1938cited by this paper

• Unremitting Neonatal Jaundice: A Diagnostic Challenge

  2026cites this paper
• Troubles constitutionnels du métabolisme de la bilirubine

  2024cites this paper
• Repeated dosing of AAV-mediated liver gene therapy in juvenile rat and mouse models of Crigler-Najjar syndrome type I

  2024cites this paper
• Type II Crigler-Najjar syndrome: a case report and literature review

  2024cites this paper
• A “Gold Standard” Test for Diagnosing and Quantifying Hemolysis in Neonates and Infants

  2023cites this paper
• Gene Therapy in Patients with the Crigler-Najjar Syndrome.

  2023cites this paper
• Case report: Crigler-Najjar syndrome type 1 in Croatia—more than a one in a million: a case series

  2023cites this paper
• Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model

  2023cites this paper
• Blue light induces ROS mediated apoptosis and degradation of AML1-ETO oncoprotein in Kasumi-1 cells

  2022cites this paper
• Blue-Green (~480 nm) versus Blue (~460 nm) Light for Newborn Phototherapy—Safety Considerations

  2022cites this paper
• Models of bilirubin neurological damage: lessons learned and new challenges

  2022cites this paper
• Role of ursodeoxycholic acid in neonatal indirect hyperbilirubinemia: a systematic review and meta-analysis of randomized controlled trials

  2022cites this paper
• CAQ Corner: Genetic liver disease

  2022cites this paper
• Perioperative Management of Patient with Esophageal Carcinoma and Crigler-Najjar Syndrome Type 2: A Case Report

  2022cites this paper
• Liver Transplantation: Certificate of Added Qualification (CAQ) Section - Genetic Liver Disease.

  2022cites this paper
• Disease burden and management of Crigler‐Najjar syndrome: Report of a world registry

  2022cites this paper
• Hemolytic causes of neonatal jaundice: diagnosis and treatment

  2021cites this paper
• Jaundice

  2021cites this paper
• UGT1A1-related Bilirubin Encephalopathy/Kernicterus in Adults

  2021cites this paper
• Neonatal Hyperbilirubinemia in Low-Income African Countries

  2021cites this paper
• Severe neonatal hyperbilirubinemia and the brain: the old but still evolving story

  2021cites this paper
• Effects of high bilirubin level in pregnancy in Crigler-Najjar syndrome type 2: An extremely rare but important clinical entity to recognize.

  2021cites this paper
• Low efficacy of recombinant SV40 in Ugt1a1-/- mice with severe inherited hyperbilirubinemia

  2021cites this paper
• Pediatric metabolic liver diseases: Evolving role of liver transplantation

  2021cites this paper
• [Liver histologic changes in children with type 1 of Crigler-Najjar syndrome].

  2021cites this paper
• Crigler‐Najjar Syndrome Type 1: Pathophysiology, Natural History, and Therapeutic Frontier

  2020influential citation
• Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients

  2020cites this paper
• Disorders of Bilirubin Metabolism

  2020cites this paper
• A Quantitative In Vitro Potency Assay for Adeno-Associated Virus Vectors Encoding for the UGT1A1 Transgene

  2020cites this paper
• Disease burden of Crigler–Najjar syndrome: Systematic review and future perspectives

  2020cites this paper
• The Role of Bilirubin and the Other “Yellow Players” in Neurodegenerative Diseases

  2020cites this paper
• Bile Pigment Metabolism and Its Disorders

  2020cites this paper
• Gene Therapy in Pediatric Liver Disease

  2019cites this paper
• Essentials of Hepatology

  2019cites this paper
• Prevalence and Relevance of Pre-Existing Anti-Adeno-Associated Virus Immunity in the Context of Gene Therapy for Crigler–Najjar Syndrome

  2019influential citation
• Elucidating the interaction of ticlopidine with serum albumin and its role in bilirubin displacement in vitro

  2019cites this paper
• Advances in understanding disease mechanisms and potential treatments for Crigler–Najjar syndrome

  2018influential citation
• Jaundice and Cholestasis

  2018cites this paper
• Phototherapie bei dermatologischen Erkrankungen

  2018cites this paper
• Crigler-Najjar Syndrome Type 2 in Pregnancy: A Rare Case Report

  2018cites this paper
• Hemolysis and Glucose-6-Phosphate Dehydrogenase Deficiency-Related Neonatal Hyperbilirubinemia

  2018cites this paper
• Quantitative Systems Pharmacology Model of hUGT1A1‐modRNA Encoding for the UGT1A1 Enzyme to Treat Crigler‐Najjar Syndrome Type 1

  2018cites this paper
• AAV8 Gene Therapy Rescues the Newborn Phenotype of a Mouse Model of Crigler–Najjar

  2018cites this paper
• Bacterial Outer Membrane Vesicles from Dextran Sulfate Sodium–Induced Colitis Differentially Regulate Intestinal UDP-Glucuronosyltransferase 1A1 Partially Through Toll-Like Receptor 4/Mitogen-Activated Protein Kinase/Phosphatidylinositol 3-Kinase Pathway

  2018cites this paper
• Evaluation of region selective bilirubin-induced brain damage as a basis for a pharmacological treatment

  2017cites this paper
• Evaluating the regenerative potential and functionality of human liver cells in mice.

  2017cites this paper
• Bacterial outer membrane vesicles from dextran sulfate sodium-induced colitis differentially regulate intestinal UDP-glucuronosyltransferase 1 A 1 partially through TLR 4 / MAPK / PI 3 K pathway

  2017cites this paper
• Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo

  2017cites this paper
• Hepatic Parenchymal Injury in Crigler-Najjar Type I

  2017cites this paper
• Recurrence of primary glomerulonephritis: Review of the current evidence

  2017cites this paper
• Effect of Ursodeoxycholic Acid on Indirect Hyperbilirubinemia in Neonates Treated With Phototherapy

  2017cites this paper
• Germline genetic variants with implications for disease risk and therapeutic outcomes.

  2017cites this paper
• A translationally optimized AAV-UGT1A1 vector drives safe and long-lasting correction of Crigler-Najjar syndrome

  2016cites this paper
• Troubles constitutionnels du métabolisme de la bilirubine

  2016cites this paper
• Effect of Ursodeoxycholic Acid on Indirect Hyperbilirubinemia in Neonates Treated With Phototherapy

  2016cites this paper
• Acute cholangitis in an old patient with Crigler-Najjar syndrome type II - a case report

  2016cites this paper
• Progress toward improved therapies for inborn errors of metabolism.

  2016cites this paper
• Extreme Hyperbilirubinemia and G6PD Deficiency With No Laboratory Evidence of Hemolysis

  2016cites this paper
• Liver transplantation for pediatric inherited metabolic disorders: Considerations for indications, complications, and perioperative management

  2016cites this paper
• Treatment of Hyperbilirubinemia in Newborns

  2016cites this paper
• Preparation and Adsorption Properties of Novel Porous Microspheres with Different Concentrations of Bilirubin

  2016cites this paper
• A Randomized Trial of Phototherapy with Filtered Sunlight in African Neonates.

  2015cites this paper
• [A 14-day-old boy with jaundice and apnoea].

  2015cites this paper
• Safe and symptomatic medicinal use of surface-functionalized Mn3O4 nanoparticles for hyperbilirubinemia treatment in mice.

  2015cites this paper
• Impairment of enzymatic antioxidant defenses is associated with bilirubin-induced neuronal cell death in the cerebellum of Ugt1 KO mice

  2015cites this paper
• Prospective Randomized Long-Term Study on the Efficacy and Safety of UV-Free Blue Light for Treating Mild Psoriasis Vulgaris

  2015cites this paper
• De Novo Donor‐Specific HLA Antibody Formation in Two Patients With Crigler‐Najjar Syndrome Type I Following Human Hepatocyte Transplantation With Partial Hepatectomy Preconditioning

  2015cites this paper
• Efficiency of rifampicin in emergency treatment of severe hyperbilirubinemia : report of two cases and review of literature.

  2015cites this paper
• Sister Jean Ward, phototherapy, and jaundice: a unique human and photochemical interaction

  2015cites this paper
• Liver transplantation for treatment of severe S-adenosylhomocysteine hydrolase deficiency.

  2015cites this paper
• Gene Replacement Therapy for Genetic Hepatocellular Jaundice

  2015cites this paper
• Gene Therapy for Inherited Diseases of Liver Metabolism

  2015cites this paper
• Progress and challenges in gene therapy for Crigler–Najjar syndrome

  2015cites this paper
• Hyperbilirubinemia, hemolysis, and increased bilirubin neurotoxicity.

  2014cites this paper
• Correction of Hyperbilirubinemia in Gunn Rats by Surgical Delivery of Low Doses of Helper-Dependent Adenoviral Vectors

  2014cites this paper
• Evaluation of the pediatric patient for liver transplantation: 2014 practice guideline by the american association for the study of liver diseases, american society of transplantation and the north american society for pediatric gastroenterology, hepatology and nutrition

  2014cites this paper
• Unprecedented catalytic activity of Mn3O4 nanoparticles: potential lead of a sustainable therapeutic agent for hyperbilirubinemia

  2014cites this paper
• Diagnosis and Treatment of Unconjugated Hyperbilirubinemia

  2014cites this paper
• AASLD PRACTICE GUIDELINE Evaluation of the Pediatric Patient for Liver Transplantation: 2014 Practice Guideline by the American Association for the Study of Liver Diseases, American Society of Transplantation and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

  2014cites this paper
• Therapeutic hepatocyte transplant for inherited metabolic disorders: functional considerations, recent outcomes and future prospects

  2014cites this paper
• Phototherapy device effectiveness in Nigeria: irradiance assessment and potential for improvement.

  2013cites this paper
• Recommendations for pregnancies in patients with crigler-najjar syndrome.

  2013cites this paper
• In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV

  2013cites this paper
• Neurophysiological follow-up of two siblings with Crigler-Najjar syndrome type I and review of literature.

  2013cites this paper
• Improved Efficacy and Reduced Toxicity by Ultrasound-Guided Intrahepatic Injections of Helper-Dependent Adenoviral Vector in Gunn Rats

  2013cites this paper
• UGT1A1 genetic analysis as a diagnostic aid for individuals with unconjugated hyperbilirubinemia.

  2013cites this paper
• Amish revisited: next-generation sequencing studies of psychiatric disorders among the Plain people.

  2013cites this paper
• Evaluation of window-tinting films for sunlight phototherapy.

  2013cites this paper
• Bile Pigment Metabolism and Its Disorders

  2013cites this paper
• Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups

  2012cites this paper
• Bilirrubina, una vieja amiga con una nueva historia

  2012cites this paper
• New pathophysiological concepts underlying pathogenesis of pigment gallstones.

  2012cites this paper
• Application of whole-organ tissue engineering in hepatology

  2012cites this paper
• Sustained Reduction of Hyperbilirubinemia in Gunn Rats After Adeno-Associated Virus-Mediated Gene Transfer of Bilirubin UDP-Glucuronosyltransferase Isozyme 1A1 to Skeletal Muscle

  2012influential citation
• Rescue of bilirubin-induced neonatal lethality in a mouse model of Crigler-Najjar syndrome type I by AAV9-mediated gene transfer

  2012cites this paper
• Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia.

  2012cites this paper
• Tin-mesoporphyrin in the treatment of refractory hyperbilirubinemia due to Rh incompatibility

  2012cites this paper
• Evaluating the Beneficial and Detrimental Effects of Bile Pigments in Early and Later Life

  2012cites this paper
• Hepatocyte transplantation for inherited metabolic diseases of the liver

  2012cites this paper
• Vector and Helper Genome Rearrangements Occur During Production of Helper-Dependent Adenoviral Vectors

  2012cites this paper