Non‐homologous DNA end joining in the mature rat brain

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of Neurochemistry

• Publication date

  2002-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.0022-3042.2002.00776.xPMID 11953445
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Concurrent expression of recombination activating genes 1 and 2 in zebrafish olfactory sensory neurons

  2001cited by this paper
• Double-strand-break-induced homologous recombination in mammalian cells.

  2001cited by this paper
• DNA recombination as a possible mechanism in declarative memory: A hypothesis

  2001cited by this paper
• Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.

  2001cited by this paper
• The role of DNA polymerase activity in human non-homologous end joining.

  2001cited by this paper
• Interactions of the DNA Ligase IV-XRCC4 Complex with DNA Ends and the DNA-dependent Protein Kinase*

  2000cited by this paper
• Expression of DNA-dependent protein kinase catalytic subunit and Ku80 in developing human brains: implication of DNA-repair in neurogenesis.

  2000cited by this paper
• Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase β

  2000cited by this paper
• Defective embryonic neurogenesis in Ku-deficient but not DNA-dependent protein kinase catalytic subunit-deficient mice.

  2000cited by this paper
• Spatial and temporal changes in natural and target deprivation-induced cell death in the mouse inferior olive.

  2000cited by this paper
• DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway.

  2000cited by this paper
• The recombination-activating gene 1 of Pleurodeles waltl (urodele amphibian) is transcribed in lymphoid tissues and in the central nervous system

  2000cited by this paper
• Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm.

  2000influential reference
• Xrcc2 is required for genetic stability, embryonic neurogenesis and viability in mice

  2000cited by this paper
• Cell birth, cell death, cell diversity and DNA breaks: how do they all fit together?

  2000cited by this paper
• Mouse testicular extracts process DNA double-strand breaks efficiently by DNA end-to-end joining.

  1999cited by this paper
• Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins.

  1999cited by this paper
• Ku-Dependent Nonhomologous DNA End Joining inXenopus Egg Extracts

  1999influential reference
• The mammalian Mre11-Rad50-nbs1 protein complex: integration of functions in the cellular DNA-damage response.

  1999cited by this paper
• Rearranging views on neurogenesis: neuronal death in the absence of DNA end-joining proteins.

  1999cited by this paper
• DNA end-joining: from yeast to man.

  1998cited by this paper
• Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice.

  1998cited by this paper
• Immune receptor editing: revise and select.

  1998cited by this paper
• DNA end-joining catalyzed by human cell-free extracts.

  1998cited by this paper
• A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis.

  1998influential reference
• Detection of excision nuclease in cell-free extracts from the adult mammalian brain.

  1998cited by this paper
• Warner-Lambert/Parke-Davis Award Lecture. Pathological and physiological double-strand breaks: roles in cancer, aging, and the immune system.

  1998cited by this paper
• Pathological and Physiological Double-Strand Breaks: Roles in Cancer, Aging, and the Immune System

  1998cited by this paper
• Early Developmental Destruction of Terminals in the Striatal Target Induces Apoptosis in Dopamine Neurons of the Substantia Nigra

  1997cited by this paper
• Rapid accumulation of genome rearrangements in liver but not in brain of old mice

  1997cited by this paper
• Apoptosis and Its Relation to the Cell Cycle in the Developing Cerebral Cortex

  1997cited by this paper
• Mammalian DNA ligases

  1997influential reference
• DNA Ligase IV from HeLa Cell Nuclei*

  1996cited by this paper
• Mechanisms of nonhomologous DNA end-joining in frogs, mice and men.

  1996influential reference
• The identification and characterization of mammalian proteins involved in the rejoining of DNA double-strand breaks in vitro.

  1996cited by this paper
• Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex.

  1996cited by this paper
• V(D)J recombination pathology.

  1996cited by this paper
• DNA mismatch repair and DNA methylation in adult brain neurons

  1996cited by this paper
• V(D)J recombination and double-strand break repair.

  1995cited by this paper
• DNA end-joining in extracts from human cells.

  1995cited by this paper
• Menage á trois: Double strand break repair, V(D)J recombination and DNA‐PK

  1995cited by this paper
• Physiological concentrations of purines and pyrimidines

  1994influential reference
• Mammalian DNA ligases.

  1992cited by this paper
• Purification and properties of two DNA ligases from human placenta.

  1986cited by this paper
• Changes of DNA ligase in developing rat brain.

  1977cited by this paper
• Inhibition of chick embryo DNA ligase by dATP: its use in enzyme purification.

  1976cited by this paper

• Tissue-Specific Activation of Microhomology-Mediated End Joining with Age Reflects Dynamic Rewiring of DNA Repair in Rats

  2025cites this paper
• Mechanisms of DNA Damage Response in Mammalian Oocytes.

  2024cites this paper
• Progerin Can Induce DNA Damage in the Absence of Global Changes in Replication or Cell Proliferation

  2024cites this paper
• Metabolic slowdown as the proximal cause of ageing and death

  2023cites this paper
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• Genetic therapies for neurological disorders

  2021cites this paper
• Alteration of genetic recombination and double-strand break repair in human cells by progerin expression.

  2020cites this paper
• Leveraging DNA Damage Response Pathways to Enhance the Precision of CRISPR-Mediated Genome Editing

  2020cites this paper
• Advances in genome editing through control of DNA repair pathways

  2019cites this paper
• Colocalization of BRCA1 with Tau Aggregates in Human Tauopathies

  2019cites this paper
• Aging and the Brain

  2018cites this paper
• Nuclear Genomic Instability and Aging.

  2018cites this paper
• Does a senescene-like phenotype in neurons contribute to brain ageing and neurodegeneration?

  2018cites this paper
• The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like State?

  2017cites this paper
• Aging impairs double‐strand break repair by homologous recombination in Drosophila germ cells

  2016cites this paper
• Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans

  2016cites this paper
• The Role of Transposable Elements in TDP-43-Mediated Neurodegeneration

  2016cites this paper
• DNA double strand break repair, aging and the chromatin connection.

  2016cites this paper
• Early age decline in DNA repair capacity in the liver: in depth profile of differential gene expression

  2016cites this paper
• Identification and Characterization of the V(D)J Recombination Activating Gene 1 in Long-Term Memory of Context Fear Conditioning

  2015cites this paper
• The Ku heterodimer: function in DNA repair and beyond.

  2015cites this paper
• BRCA1 Silencing Is Associated with Failure of DNA Repairing in Retinal Neurocytes

  2014influential citation
• Knock-In Reporter Mice Demonstrate that DNA Repair by Non-homologous End Joining Declines with Age

  2014cites this paper
• Ageing of the male germ line

  2013cites this paper
• Voluntary Running in Young Adult Mice Reduces Anxiety-Like Behavior and Increases the Accumulation of Bioactive Lipids in the Cerebral Cortex

  2013cites this paper
• DNA double-strand break response in stem cells: mechanisms to maintain genomic integrity.

  2013cites this paper
• Longevity Assurance by Genome Maintenance

  2013cites this paper
• Neuronal DNA Double Strand Break Damage and Repair Following Sublethal iGluR Activation, and the Neuroprotective Effects of Melatonin

  2013cites this paper
• Age and gender effects on DNA strand break repair in peripheral blood mononuclear cells

  2013cites this paper
• Age and Oxidative Stress in the Germ Line

  2012cites this paper
• Nuclear and Mitochondrial DNA Repair in Selected Eukaryotic Aging Model Systems

  2012cites this paper
• Oxidative DNA Damage in Neurons: Implication of Ku in Neuronal Homeostasis and Survival

  2012cites this paper
• DNA Repair Defects and DNA-PK in Neurodegeneration.

  2012cites this paper
• DNA Repair Defects and DNA-PK in Neurodegeneration

  2012cites this paper
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  2011cites this paper
• Metabolism, Genomics, and DNA Repair in the Mouse Aging Liver

  2011cites this paper
• Efficient mutagenesis of the rhodopsin gene in rod photoreceptor neurons in mice

  2011cites this paper
• Topoisomerase IIβ associates with Ku70 and PARP-1 during double strand break repair of DNA in neurons.

  2011cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2008cites this paper
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  2008cites this paper
• Positive Regulation of DNA Double Strand Break Repair Activity during Differentiation of Long Life Span Cells: The Example of Adipogenesis

  2008cites this paper
• DNA double-strand breaks: a potential causative factor for mammalian aging?

  2008cites this paper
• The localization of c-Abl in Alzheimer's disease

  2008cites this paper
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  2007cites this paper
• Mechanisms of disease: DNA repair defects and neurological disease.

  2007cites this paper
• DNA repair in neurons: so if they don't divide what's to repair?

  2007cites this paper
• DNA repair in aging rat neurons.

  2007cites this paper
• DNA damage, cellular senescence and organismal ageing: causal or correlative?

  2007cites this paper
• Mechanisms of Disease: DNA repair defects and neurological disease

  2007cites this paper
• Changes in DNA repair during aging

  2007cites this paper
• Alzheimer’s disease, brain immune privilege and memory: a hypothesis

  2006cites this paper
• "The seven sins" of the Hebbian synapse: can the hypothesis of synaptic plasticity explain long-term memory consolidation?

  2006cites this paper
• DNA double strand break repair in brain: reduced NHEJ activity in aging rat neurons.

  2006cites this paper
• An Inhibitor of DNA Recombination Blocks Memory Consolidation, But Not Reconsolidation, in Context Fear Conditioning

  2006cites this paper
• DNA end joining activity is reduced in Alzheimer's disease.

  2006cites this paper
• Rapid phosphorylation of histone H2A.X following ionotropic glutamate receptor activation

  2006cites this paper
• DNA repair in post-mitotic neurons: a gene-trapping strategy

  2005cites this paper
• Making ends meet in old age: DSB repair and aging.

  2005cites this paper
• Nonhomologous end joining of complementary and noncomplementary DNA termini in mouse testicular extracts.

  2004cites this paper
• Development of a rapid, small-scale DNA repair assay for use on clinical samples.

  2003cites this paper
• Experience-dependent expression of terminal deoxynucleotidyl transferase in mouse brain

  2003cites this paper
• The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion.

  2003cites this paper
• DNA-polymerase alpha, beta, delta and epsilon activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex.

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• DNA‐polymerase α, β, δ and ε activities in isolated neuronal and astroglial cell fractions from developing and aging rat cerebral cortex

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