Applications of Hodgkin-Huxley equations to excitable tissues.

No abstract is available for this paper.

• Publication year

  1966

• Venue

  Physiological Reviews

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Physics

• Identifiers
  DOI 10.1152/PHYSREV.1966.46.1.1PMID 5323501
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Computed action potential in nerve from Xenopus laevis.

  1965cited by this paper
• ACCOMMODATION IN MYELINATED NERVE FIBRES OF XENOPUS LAEVIS AS COMPUTED ON THE BASIS OF VOLTAGE CLAMP DATA.

  1965cited by this paper
• The effect of changing the internal solution on sodium inactivation and related phenomena in giant axons.

  1965cited by this paper
• Voltage clamp experiments on internally perfused giant axons.

  1965cited by this paper
• Hodgkin-Huxley Equations: Logarithmic Relation between Membrane Current and Frequency of Repetitive Activity

  1964cited by this paper
• ACCOMMODATION RELATED TO INACTIVATION OF THE SODIUM PERMEABILITY IN SINGLE MYELINATED NERVE FIBRES FROM XENOPUS LAEVIS.

  1964cited by this paper
• Linear electrical properties of striated muscle fibres observed with intracellular electrodes

  1964cited by this paper
• An analysis of the transverse electrical impedance of striated muscle

  1964cited by this paper
• The action potential in the myelinated nerve fibre of Xenopus laevis as computed on the basis of voltage clamp data

  1964cited by this paper
• EXCITATION AND EXCITATION-CONTRACTION COUPLING IN CARDIAC MUSCLE.

  1964cited by this paper
• The specificity of the initial current in myelinated nerve fibres of Xenopus laevis. Voltage clamp experiments

  1963cited by this paper
• Dependence of resting and action potentials on internal potassium in perfused squid giant axons

  1963cited by this paper
• The effect of temperature on the sodium and potassium permeability changes in myelinated nerve fibres of Xenopus laevis

  1963cited by this paper
• Current—voltage relations of Purkinje fibres in sodium‐deficient solutions

  1963cited by this paper
• Transient Responses of Purkinje Fibres to Non-uniform Currents

  1963cited by this paper
• A quantitative description of potassium currents in myelinated nerve fibres of Xenopus laevis

  1963cited by this paper
• THE SQUID GIANT AXON. MATHEMATICAL MODELS.

  1963cited by this paper
• The Conditions for Initiating "All-or-Nothing" Repolarization in Cardiac Muscle.

  1963cited by this paper
• Inactivation of the sodium‐carrying mechanism in myelinated nerve fibres of Xenopus laevis

  1963cited by this paper
• Some comments on the Hodgkin-Huxley equations.

  1963cited by this paper
• PERMEABILITY OF HEART MUSCLE TO CHOLINE.

  1963cited by this paper
• The effects of changes in internal ionic concentrations on the electrical properties of perfused giant axons

  1962cited by this paper
• Membrane Potentials of the Lobster Giant Axon Obtained by Use of the Sucrose-Gap Technique

  1962cited by this paper
• Contraction and Action Potentials of Frog Heart Muscles Soaked in Sucrose Solution

  1962cited by this paper
• The potassium and chloride conductance of frog muscle membrane

  1962cited by this paper
• Replacement of the axoplasm of giant nerve fibres with artificial solutions

  1962cited by this paper
• Potassium conductance of frog muscle membrane under controlled voltage

  1962cited by this paper
• The voltage dependence of the cardiac membrane conductance.

  1962cited by this paper
• Delayed Rectification and Anomalous Rectification in Frog's Skeletal Muscle Membrane

  1962cited by this paper
• Membrane ionic permeabilities during the cardiac action potential.

  1962cited by this paper
• Effect of sodium-deficiency on the membrane activity of the frog's heart.

  1962cited by this paper
• Further observations on resting and action potential of intracellularly perfused squid axon.

  1962cited by this paper
• Electrical and mechanical activity of frog's heart in electrolyte-free solutions.

  1962cited by this paper
• Potassium permeability in myelinated nerve fibres of Xenopus laevis

  1962cited by this paper
• A modification of the Hodgkin—Huxley equations applicable to Purkinje fibre action and pacemaker potentials

  1962cited by this paper
• Instantaneous potassium currents in myelinated nerve fibres of Xenopus laevis

  1962cited by this paper
• Membrane currents in spinal motoneurons associated with the action potential and synaptic activity.

  1962cited by this paper
• Delayed currents in myelinated nerve fibres of Xenopus laevis investigated with voltage clamp technique

  1962cited by this paper
• Current-Voltage Relations in the Lobster Giant Axon Membrane Under Voltage Clamp Conditions

  1962cited by this paper
• Computation of impulse initiation and saltatory conduction in a myelinated nerve fiber.

  1962cited by this paper
• Evidence for Independence of Voltage of the Membrane Conductance of Rabbit Ventricular Fibres

  1961cited by this paper
• Solutions of the Hodgkin-Huxley equations for squid axon treated with tetraethylammonium and in potassium-rich media.

  1961cited by this paper
• Methods for perfusing the giant axon of Loligo pealii.

  1961cited by this paper
• Anion conductance of cardiac muscle

  1961cited by this paper
• Chloride ions and the membrane potential of Purkinje fibres

  1961cited by this paper
• Sodium permeability in toad nerve and in squid nerve

  1960cited by this paper
• Potassium ion current in the squid giant axon: dynamic characteristic.

  1960cited by this paper
• Thresholds and Plateaus in the Hodgkin-Huxley Nerve Equations

  1960cited by this paper
• Ionic Current Measurements in the Squid Giant Axon Membrane

  1960cited by this paper
• Cardiac Action and Pacemaker Potentials based on the Hodgkin-Huxley Equations

  1960cited by this paper
• Rectifying Properties of Heart Muscle

  1960cited by this paper
• Analysis of certain errors in squid axon voltage clamp measurements.

  1960cited by this paper
• The chloride conductance of frog skeletal muscle

  1960cited by this paper
• Quantitative description of sodium currents in myelinated nerve fibres of Xenopus laevis

  1960cited by this paper
• The sodium‐potassium hypothesis as the basis of electrical activity in frog ventricle

  1960cited by this paper
• ION MOVEMENTS DURING NERVE ACTIVITY

  1959cited by this paper
• The influence of potassium and chloride ions on the membrane potential of single muscle fibres

  1959cited by this paper
• Steady state inactivation of sodium permeability in myelinated nerve fibres of Xenopus laevis

  1959cited by this paper
• Excitation of the Squid Axon Membrane in Isosmotic Potassium Chloride

  1959cited by this paper
• Sodium currents in the myelinated nerve fibre of Xenopus laevis investigated with the voltage clamp technique

  1959cited by this paper
• Membrane potential change and membrane current in supramedullary nerve cell of puffer.

  1959cited by this paper
• Discrete threshold and repetitive responses in the squid axon under voltage-clamp.

  1958cited by this paper
• The Croonian Lecture - Ionic movements and electrical activity in giant nerve fibres

  1958cited by this paper
• PROLONGED ACTION POTENTIALS FROM SINGLE NODES OF RANVIER

  1958cited by this paper
• PROPAGATED REPOLARIZATION IN HEART MUSCLE

  1958cited by this paper
• [Measurement of the membrane resistance of the ventricular myocardium of mammals during activity].

  1958cited by this paper
• Nonuniform response in the squid axon membrana under voltage-clamp.

  1958cited by this paper
• Membrane currents in isolated frog nerve fibre under voltage clamp conditions

  1958cited by this paper
• Membrane excitation of the Hodgkin-Huxley axon; preliminary corrections.

  1958cited by this paper
• The action of calcium on the electrical properties of squid axons

  1957cited by this paper
• DEMONSTRATION OF TWO STABLE POTENTIAL STATES IN THE SQUID GIANT AXON UNDER TETRAETHYLAMMONIUM CHLORIDE

  1957cited by this paper
• EFFECTS OF SODIUM AND POTASSIUM ON REPOLARIZATION IN FROG VENTRICULAR FIBERS

  1957cited by this paper
• Shortening of the cardiac action potential due to a brief injection of KCl following the onset of activity

  1956cited by this paper
• The after‐effects of impulses in the giant nerve fibres of Loligo

  1956cited by this paper
• The electrical properties of the slow muscle fibre membrane

  1956cited by this paper
• VAGAL AND SYMPATHETIC EFFECTS ON THE PACEMAKER FIBERS IN THE SINUS VENOSUS OF THE HEART

  1956cited by this paper
• The effect of the cardiac membrane potential on the rapid availability of the sodium‐carrying system

  1955cited by this paper
• A new method for measuring membrane potentials with external electrodes.

  1954cited by this paper
• Movement of radioactive potassium and membrane current in a giant axon

  1953cited by this paper
• The components of membrane conductance in the giant axon of Loligo

  1952cited by this paper
• Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo

  1952cited by this paper
• A quantitative description of membrane current and its application to conduction and excitation in nerve

  1952cited by this paper
• The electrical constants of Purkinje fibres

  1952cited by this paper
• The dual effect of membrane potential on sodium conductance in the giant axon of Loligo

  1952cited by this paper
• Saltatory conduction in myelinated nerve fibres

  1952cited by this paper
• Measurement of current‐voltage relations in the membrane of the giant axon of Loligo

  1952cited by this paper
• [The hypothesis of saltatory conduction].

  1952cited by this paper
• Effect of current flow on the membrane potential of cardiac muscle

  1951cited by this paper
• Effect of potassium and sodium on resting and action potentials of single myelinated nerve fibres

  1951cited by this paper
• Electrical characteristics of injury potentials.

  1951cited by this paper
• Cardiac resting and action potentials recorded with an intracellular electrode

  1951cited by this paper
• The effect of temperature on the electrical activity of the giant axon of the squid

  1949cited by this paper
• The effect of sodium ions on the electrical activity of the giant axon of the squid

  1949cited by this paper
• Studies on the axon membrane; a new method.

  1949cited by this paper
• Electrical characteristics of injuries to heart muscle.

  1947cited by this paper
• The electrical constants of a crustacean nerve fibre

  1946cited by this paper
• MEMBRANE POTENTIAL OF THE SQUID GIANT AXON DURING CURRENT FLOW

  1941cited by this paper
• RECTIFICATION AND INDUCTANCE IN THE SQUID GIANT AXON

  1941cited by this paper
• LONGITUDINAL IMPEDANCE OF THE SQUID GIANT AXON

  1941cited by this paper
• MEMBRANE AND PROTOPLASM RESISTANCE IN THE SQUID GIANT AXON

  1939cited by this paper

• A Two-part Approach to the Hodgkin-Huxley Project: Challenging Students to Build Deterministic and Stochastic Models of Ion Channel Behavior

  2025cites this paper
• A novel SCN3B in-frame codon deletion in a Brugada syndrome patient: Implications for disrupted NaV1.5 function.

  2025cites this paper
• Magnetomyographic evaluation of motor unit size that is robust to changes in distance to sensor

  2025cites this paper
• Digital twin for atrial fibrillation: fundamentals, current advances, challenges and future perspectives

  2025cites this paper
• Low-Power Memristor for Neuromorphic Computing: From Materials to Applications

  2025cites this paper
• Nonlinear resonance and circuit implement of a neuron driven by memristive current

  2025cites this paper
• Visualization of axonal and volume currents in median nerve compound action potential using magnetoneurography.

  2023cites this paper
• Assessment of thoracic spinal cord electrophysiological activity through magnetoneurography.

  2021cites this paper
• Decreased excitability of locus coeruleus neurons during hypercapnia is exaggerated in the streptozotocin-model of Alzheimer's disease.

  2020cites this paper
• Coupling synchronization between photoelectric neurons by using memristive synapse

  2020cites this paper
• Visualization of electrophysiological activity at the carpal tunnel area using magnetoneurography.

  2019cites this paper
• Normalisation de la fréquence cardiaque et de la conduction auriculo-ventriculaire dans des modèles de bradycardie congénitale par l'inhibition pharmacologique du courant IkACh

  2019cites this paper
• System for Nature-inspired Signal Processing: Principles and Practice

  2019cites this paper
• The free energy of biomembrane and nerve excitation and the role of anesthetics.

  2018cites this paper
• Information sensitivity functions to assess parameter information gain and identifiability of dynamical systems

  2017cites this paper
• New Types of Experiments Reveal that a Neuron Functions as Multiple Independent Threshold Units

  2017cites this paper
• The influence of increased membrane conductance on response properties of spinal motoneurons.

  2016cites this paper
• Handbook of ion channels

  2015cites this paper
• Nonlinear and Stochastic Dynamics in the Heart.

  2014cites this paper
• 4. Active Behavior of the Cell Membrane

  2014influential citation
• Complex Structure and Dynamics of the Heart

  2014cites this paper
• Transient impairment of the axolemma following regional anaesthesia by lidocaine in humans

  2014cites this paper
• Human cardiac systems electrophysiology and arrhythmogenesis: iteration of experiment and computation.

  2014cites this paper
• What gets a cell excited? Kinky curves.

  2014cites this paper
• Early afterdepolarizations in cardiac myocytes: beyond reduced repolarization reserve.

  2013cites this paper
• Biophysical mechanism of spike threshold dependence on the rate of rise of the membrane potential by sodium channel inactivation or subthreshold axonal potassium current

  2013cites this paper
• How the Hodgkin–Huxley equations inspired the Cardiac Physiome Project

  2012cites this paper
• Mechanisms and Determinants of Ultralong Action Potential Duration and Slow Rate-Dependence in Cardiac Myocytes

  2012cites this paper
• Defining and modeling known adverse outcome pathways: Domoic acid and neuronal signaling as a case study

  2011cites this paper
• Axon physiology.

  2011cites this paper
• Skin Thermal Pain Modeling

  2011cites this paper
• Locally Adaptive Time Stepping in Numerical Simulations for Neuroscience

  2011cites this paper
• Emergence of Resonances in Neural Systems: The Interplay between Adaptive Threshold and Short-Term Synaptic Plasticity

  2011cites this paper
• A multi-scale view of skin thermal pain: from nociception to pain sensation

  2010cites this paper
• Short-Term Synaptic Plasticity: Computational implications in the emergent behavior of neural systems

  2009cites this paper
• Polypeptide models for membrane permeation by cations and their relevance to biomembrane depolarization

  2009cites this paper
• Skin thermal pain modeling—A holistic method

  2008cites this paper
• Two Components of the Cardiac Action Potential I. Voltage-time Course and the Effect of Acet.flcholine on Atrial and Nodal Cells of the Rabbit Heart the Journal of General Physiology

  2008cites this paper
• K+ channels at the axon initial segment dampen near-threshold excitability of neocortical fast-spiking GABAergic interneurons.

  2008cites this paper
• Modeling of nociceptor transduction in skin thermal pain sensation.

  2008cites this paper
• Skin thermal pain modeling — A holistic method

  2008cites this paper
• Fixed threshold modeling of an adjustable threshold integrate-and-fire neuronal model

  2008cites this paper
• Role for the subthreshold currents ILeak and IH in the homeostatic control of excitability in neocortical somatostatin-positive inhibitory neurons.

  2006cites this paper
• Innerneurale Homöostase und Kommunikation, Erregung

  2006cites this paper
• Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting

  2006cites this paper
• Somatostatin-Positive Inhibitory Neurons Homeostatic Control of Excitability in Neocortical in theH I and Leak I Role for the Subthreshold Currents

  2006cites this paper
• Dynamic spatiotemporal synaptic integration in cortical neurons: neuronal gain, revisited.

  2005cites this paper
• ELECTROPHYSIOLOGY OF THE PERINODAL FIBERS 491 a junctional zone before reaching the crista terminaUs

  2005cites this paper
• Stimulus-Dependent Changes in Spike Threshold Enhance Feature Selectivity in Rat Barrel Cortex Neurons

  2005cites this paper
• The effect of tetrodotoxin on the membrane current in cardiac muscle (Purkinje fibers)

  2005cites this paper
• Voltage clamp experiments on frog atrial heart muscle fibres with the sucrose gap technique

  2004cites this paper
• Voltage clamp experiments on frog atrial heart muscle fibres with the sucrose gap technique

  2004cites this paper
• The response of excitable membrane models to a cyclic input

  2004cites this paper
• A quantitative analysis of cell volume and resting potential determination and regulation in excitable cells

  2004cites this paper
• Low-powered and accelerative synchronization in the coupled system of nonlinear hardware oscillators

  2004cites this paper
• Ondes paroxysmales induites par le métrazol (PTZ) sur les neurones d'Helix p.: Modèle fonctionnel

  2004cites this paper
• The potassium component of membrane current in Purkinje fibers

  2004cites this paper
• The research career of Richard B. Stein (1940-).

  2004cites this paper
• Sustained spontaneous activity of ranvier nodes induced by the combined actions of TEA and lack of calcium

  2004cites this paper
• Effect of subthreshold up and down states on the whisker-evoked response in somatosensory cortex.

  2004cites this paper
• Excitability of the Clay model for squid giant axon.

  2003cites this paper
• Erregungsbildung und Erregungsleitung

  2003cites this paper
• Adaptive coincidence detection and dynamic gain control in visual cortical neurons in vivo.

  2003cites this paper
• Energy efficiency in a channel model for the spiking axon

  2003cites this paper
• Imaging of neural conduction block by neuromagnetic recording.

  2002cites this paper
• Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation

  2002cites this paper
• Teaching The Hodgkin Huxley Model: A Dynamical Approach

  2002cites this paper
• Action potential threshold of hippocampal pyramidal cells in vivo is increased by recent spiking activity.

  2001cites this paper
• A pulse-type hardware neuron model with beating, bursting excitation and plateau potential.

  2000cites this paper
• Dynamic spike threshold reveals a mechanism for synaptic coincidence detection in cortical neurons in vivo.

  2000cites this paper
• Electrical stimulation of the auditory nerve: II. Effect of stimulus waveshape on single fibre response properties.

  1999cites this paper
• Positive sharp wave and fibrillation potential modeling

  1999cites this paper
• Regulation of action-potential firing in spiny neurons of the rat neostriatum in vivo.

  1998cites this paper
• Reduction of a model for an Onchidium pacemaker neuron

  1998cites this paper
• Spike initiation and propagation in wide field transient amacrine cells of the salamander retina

  1994cites this paper
• Far‐field potentials

  1993cites this paper
• Informationsvermittlung durch elektrische Erregung

  1993cites this paper
• In vivo estimation of cardiac transmembrane current.

  1993cites this paper
• The effects of neurotransmitters on the integrative properties of spinal neurons in the lamprey.

  1993cites this paper
• Mathematical modelling of pulsatility in neuroendocrine systems

  1993influential citation
• Partition of the Hodgkin-Huxley type model parameter space into the regions of qualitatively different solutions

  1992cites this paper
• Reduction of a Hodgkin-Huxley-type model for a mammalian neuron at body temperature

  1992cites this paper
• Threshold stimulation and accommodation of the Hodgkin-Huxley axon.

  1992cites this paper
• On the Existence of Pulses in Reaction- Diffusion- Equations

  1992cites this paper
• AAEM minimonograph #10: Volume conduction

  1991cites this paper
• The singularly perturbed Hodgkin-Huxley equations as a tool for the analysis of repetitive nerve activity

  1990cites this paper
• On the description of neuronal output properties using spike train data

  1989cites this paper
• Information Transfer by Electrical Excitation

  1989cites this paper
• Chapter 26 – Signal Transmission and Processing in the Nervous System

  1988cites this paper
• Special cellular and synaptic mechanisms in motor pattern generation.

  1988cites this paper
• The adaptation ability of neuronal models subject to a current step stimulus

  1988cites this paper
• The effects of temperature on flight muscle potentials in honeybees and cuculiinid winter moths

  1988cites this paper
• 2 – Single Neurons: Spike Generation

  1987cites this paper
• Anion permeability of motor nerve terminals

  1987cites this paper
• 6 – Early and Lower-Level Vertebrate Systems

  1987cites this paper
• The Crustacean Stomatogastric System

  1987cites this paper
• Funktion der Nervenzellen

  1985cites this paper
• Interaction between a Normoxic and a Hypoxic Region of Guinea Pig and Ferret Papillary Muscles

  1985cites this paper
• Acid-base and electrolyte balance after exhausting exercise in endurance-trained and sprint-trained subjects.

  1985cites this paper
• Interaction between ventricular cells during the early part of excitation in the ferret heart.

  1985cites this paper