A fresh look at zebrafish from the perspective of cancer research

Zebrafish represent a vertebrate model organism that has been widely, and increasingly, employed over the last decade in the study of developmental processes, wound healing, microbe-host interactions, and drug screening. With the increase in the laboratory use of zebrafish, several advantages, such as a high genetic homology to humans and transparent embryos, which allow clear disease evaluation, have greatly widened its use as a model for studying tumor development in vivo. The use of zebrafish has been applied in several areas of cancer research, mainly in the following domains: (1) establishing cancer models by carcinogenic chemical, genetic technology, and xenotransplantation; (2) evaluating tumor angiogenesis; (3) studying tumor metastasis; and (4) anti-tumor drug screening and drug toxicity evaluation. In this study, we provide a comprehensive overview of the role of zebrafish in order to underline the advantages of using them as a model organism in cancer research. Several related successful events are also reviewed.

• Publication year

  2015

• Venue

  Journal of experimental & clinical cancer research : CR

• Publication date

  2015-08-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1186/s13046-015-0196-8PMID 26260237PMCID 4531851
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Supplementary Figure S1

  2019cited by this paper
• Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models

  2015cited by this paper
• PloS One 2012

  2015cited by this paper
• PLOS ONE 2013

  2015cited by this paper
• Novel mechanism of macrophage-mediated metastasis revealed in a zebrafish model of tumor development.

  2015cited by this paper
• Rapid reverse genetic screening using CRISPR in zebrafish

  2015cited by this paper
• Developing zebrafish models of autism spectrum disorder (ASD).

  2014cited by this paper
• GSTT1 Deletion Is Related to Polycyclic Aromatic Hydrocarbons-Induced DNA Damage and Lymphoma Progression

  2014cited by this paper
• Zebrafish as an emerging model for studying complex brain disorders.

  2014cited by this paper
• Zebrafish model in drug safety assessment.

  2014cited by this paper
• Quantitative Phenotyping-Based In Vivo Chemical Screening in a Zebrafish Model of Leukemia Stem Cell Xenotransplantation

  2014cited by this paper
• Xmrk, Kras and Myc Transgenic Zebrafish Liver Cancer Models Share Molecular Signatures with Subsets of Human Hepatocellular Carcinoma

  2014cited by this paper
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  2014cited by this paper
• Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

  2013influential reference
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Orthotopic transplantation of retinoblastoma cells into vitreous cavity of zebrafish for screening of anticancer drugs

  2013cited by this paper
• Anti-angiogenesis in cancer therapy: Hercules and hydra.

  2013cited by this paper
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  2013influential reference
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012influential reference
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  2012cited by this paper
• Activated ALK collaborates with MYCN in neuroblastoma pathogenesis.

  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
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  2012cited by this paper
• Vascular development in the zebrafish.

  2012cited by this paper
• Reverse genetic approaches in zebrafish.

  2012cited by this paper
• Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model

  2012cited by this paper
• An affective disorder in zebrafish with mutation of the glucocorticoid receptor

  2012cited by this paper
• Zebrafish in the study of early cardiac development.

  2012cited by this paper
• Fish pharming: zebrafish antileukemia screening.

  2012cited by this paper
• Hooked! Modeling human disease in zebrafish.

  2012cited by this paper
• Automated Whole Animal Bio-Imaging Assay for Human Cancer Dissemination

  2012cited by this paper
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  2011cited by this paper
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  2011influential reference
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  2011cited by this paper
• Zebrafish embryo, a tool to study tumor angiogenesis.

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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• Discriminating Different Cancer Cells Using a Zebrafish in Vivo Assay

  2011cited by this paper
• Pten mediates Myc oncogene dependence in a conditional zebrafish model of T cell acute lymphoblastic leukemia

  2011cited by this paper
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  2010cited by this paper
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  2010influential reference
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  2010cited by this paper
• High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia.

  2010cited by this paper
• Zebrafish models of p53 functions.

  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2009cited by this paper
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  2008cited by this paper
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• Zebrafish as a Cancer Model

  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2003cited by this paper
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