Functional impact of syntaxin on gating of N-type and Q-type calcium channels

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Nature

• Publication date

  1995-12-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/378623A0PMID 8524397
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A syntaxin-related protein controls acetylcholine release by different mechanisms in Aplysia.

  1995cited by this paper
• Pharmacological dissection of multiple types of Ca2+ channel currents in rat cerebellar granule neurons

  1995cited by this paper
• Synaptic Core Complex of Synaptobrevin, Syntaxin, and SNAP25 Forms High Affinity -SNAP Binding Site (*)

  1995cited by this paper
• Disassembly of the reconstituted synaptic vesicle membrane fusion complex in vitro.

  1995cited by this paper
• Distinct domains of syntaxin are required for synaptic vesicle fusion complex formation and dissociation.

  1995cited by this paper
• The t-SNAREs syntaxin 1 and SNAP-25 are present on organelles that participate in synaptic vesicle recycling

  1995cited by this paper
• Interaction of a synaptobrevin (VAMP)‐syntaxin complex with presynaptic calcium channels

  1995cited by this paper
• Paralysis and early death in cysteine string protein mutants of Drosophila.

  1994cited by this paper
• SNAP-25, a t-SNARE which binds to both syntaxin and synaptobrevin via domains that may form coiled coils.

  1994cited by this paper
• Localization and functional properties of a rat brain alpha 1A calcium channel reflect similarities to neuronal Q- and P-type channels.

  1994cited by this paper
• Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA.

  1994cited by this paper
• Identification of a syntaxin-binding site on N-type calcium channels.

  1994cited by this paper
• Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin

  1994cited by this paper
• Purification of the N-type calcium channel associated with syntaxin and synaptotagmin. A complex implicated in synaptic vesicle exocytosis.

  1994cited by this paper
• Cysteine string proteins: a potential link between synaptic vesicles and presynaptic Ca2+ channels.

  1994cited by this paper
• Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunits.

  1993cited by this paper
• A complex of rab3A, SNAP‐25, VAMP/synaptobrevin‐2 and syntaxins in brain presynaptic terminals

  1993cited by this paper
• Distinctive biophysical and pharmacological properties of class A (BI) calcium channel α1 subunits

  1993cited by this paper
• A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion.

  1993cited by this paper
• The syntaxin family of vesicular transport receptors.

  1993cited by this paper
• Calcium channel beta subunit heterogeneity: functional expression of cloned cDNA from heart, aorta and brain.

  1992cited by this paper
• Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones.

  1992cited by this paper
• Suppression cloning of the cDNA for a candidate subunit of a presynaptic calcium channel.

  1992cited by this paper
• Subunit stoichiometry of a mammalian K+ channel determined by construction of multimeric cDNAs.

  1992cited by this paper
• HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

  1992cited by this paper
• Primary structure and functional expression from complementary DNA of a brain calcium channel.

  1991cited by this paper
• Primary structure and functional expression from complementary DNA of a brain calcium channel

  1991cited by this paper
• Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

  1989cited by this paper
• Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse.

  1981cited by this paper
• The release of neural transmitter substances

  1969cited by this paper

• A rich conformational palette underlies human CaV2.1-channel availability

  2025cites this paper
• Early and transient increase in cortical pyramidal cell excitability and delayed alteration of evoked synaptic transmission and t-SNARE proteins content in the hippocampus and neocortex of neonatal and juvenile STXBP1 heterozygous mice

  2025cites this paper
• Interaction between CaV2.1 and Junctophilin3/4 depends on the II-III loop of CaV2.1 and on the α-helical region of Junctophilin3/4

  2025influential citation
• The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

  2024cites this paper
• Voltage-Dependent Calcium Channels in Mammalian Motor Synapses: Triggers and Modulators of Neuromuscular Transmission

  2024cites this paper
• A Rich Conformational Palette Underlies Human CaV2.1-Channel Availability

  2024influential citation
• Syntaxin11 Deficiency Inhibits CRAC Channel Priming To Suppress Cytotoxicity And Gene Expression In FHLH4 Patient T Lymphocytes

  2024cites this paper
• Regulation of Presynaptic Calcium Channels.

  2023cites this paper
• Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction

  2022cites this paper
• Human ectopic olfactory receptors and their food originated ligands: a review

  2021cites this paper
• A Qa-SNARE complex protein contributes to soybean cyst nematode resistance through regulation of mitochondria-mediated cell death.

  2021cites this paper
• Voltage‐gated calcium channel nanodomains: molecular composition and function

  2021cites this paper
• Functions of Presynaptic Voltage-gated Calcium Channels

  2020cites this paper
• Rare CACNA1A mutations leading to congenital ataxia

  2020cites this paper
• Cysteine String Proteins.

  2020cites this paper
• Polycystins as components of large multiprotein complexes of polycystin interactors.

  2020cites this paper
• Presynaptic Calcium Channels

  2019cites this paper
• Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors

  2019cites this paper
• GABA-b receptors and calcium homeostasis in medullo-spinal CSF-contacting neurons

  2019influential citation
• Recent insights into beta-cell exocytosis in type 2 diabetes.

  2019cites this paper
• GPCR regulation of secretion.

  2018cites this paper
• Exogenous alpha-Synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release alpha-Synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine

  2018cites this paper
• Calcium Channels, Synaptic Plasticity, and Neuropsychiatric Disease.

  2018cites this paper
• Novel Distinctive Roles of Docking Proteins in Short-term Synaptic Plasticity of Frog Neuromuscular Transmission Revealed by Botulinum Neurotoxins.

  2018cites this paper
• Presynaptic calcium channels.

  2018cites this paper
• N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease.

  2017cites this paper
• Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes

  2017cites this paper
• Contrôle du transfert de l'information par la dynamique calcique présynaptique aux synapses formées par les fibres moussues de l'hippocampe

  2017cites this paper
• The L-type Voltage-Gated Calcium Channel co-localizes with Syntaxin 1A in nano-clusters at the plasma membrane

  2017cites this paper
• C-terminal splice variants of P/Q-type Ca2+ channel CaV2.1 α1 subunits are differentially regulated by Rab3-interacting molecule proteins

  2017cites this paper
• Mono-ubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes

  2017cites this paper
• The role of laminins in the organization and function of neuromuscular junctions.

  2017cites this paper
• C-terminal splice variants of P/Q-type Ca channel CaV2.1

  2017cites this paper
• LRRK2 Regulates Voltage-Gated Calcium Channel Function

  2016cites this paper
• Fragile X mental retardation protein controls ion channel expression and activity

  2016cites this paper
• Cross talk between β subunits, intracellular Ca2+ signaling, and SNAREs in the modulation of CaV2.1 channel steady‐state inactivation

  2016influential citation
• The Role of Calcium Channels in Epilepsy.

  2016cites this paper
• Surface dynamics of voltage-gated ion channels

  2016cites this paper
• Calcium regulation of inhibitory synaptic transmission

  2016influential citation
• Dual roles for an intracellular calcium-signaling pathway in regulating synaptic homeostasis and neuronal excitability

  2015cites this paper
• The Arabidopsis R-SNARE VAMP721 Interacts with KAT1 and KC1 K+ Channels to Moderate K+ Current at the Plasma Membrane[OPEN]

  2015cites this paper
• G Protein Regulation of Neuronal Calcium Channels: Back to the Future

  2015cites this paper
• “Slow” Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA)

  2015cites this paper
• Overview: Presynaptic Terminal Proteins Orchestrate Stepwise Synaptic Vesicle Phases

  2015cites this paper
• Characterization of the +SSTR and ΔSSTR splice variants of the Cav2.1 P/Q-type voltage-gated calcium channel

  2015cites this paper
• Calcium Channels Interaction That Excludes Syntaxin Binding to Calcium-Activated Potassium Channel via an Syntaxin-1A Binds to and Modulates the Slo

  2015cites this paper
• Modulation and interactions of charged biomimetic membranes with bivalent ions

  2015cites this paper
• Rab3 interacting molecule 3 mutations associated with autism alter regulation of voltage-dependent Ca²⁺ channels.

  2015cites this paper
• The Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic Potential

  2015cites this paper
• Handbook of ion channels

  2015cites this paper
• MOL096008 890..906

  2015cites this paper
• JCB_201304101 1..17

  2014cites this paper
• Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density

  2014cites this paper
• Extent of Cysteine Modification of SNAP-25 In vitro

  2014cites this paper
• Fast, Ca2+-dependent exocytosis at nerve terminals: shortcomings of SNARE-based models.

  2014cites this paper
• Microsecond dissection of neurotransmitter release: SNARE-complex assembly dictates speed and Ca²⁺ sensitivity.

  2014cites this paper
• Neuronal voltage-gated calcium channels: structure, function, and dysfunction.

  2014cites this paper
• BARP suppresses voltage-gated calcium channel activity and Ca2+-evoked exocytosis

  2014cites this paper
• Exogenous α-Synuclein Decreases Raft Partitioning of Cav2.2 Channels Inducing Dopamine Release

  2014cites this paper
• Cooperative endocytosis of the endosomal SNARE protein syntaxin-8 and the potassium channel TASK-1

  2014cites this paper
• Molecular Mechanisms of Photoreceptor Synaptic Transmission

  2014cites this paper
• Vesicle-associated Membrane Protein 2 (VAMP2) but Not VAMP3 Mediates cAMP-stimulated Trafficking of the Renal Na+-K+-2Cl− Co-transporter NKCC2 in Thick Ascending Limbs*

  2014cites this paper
• Use of Synthetic Ca2+ Channel Peptides to Study Presynaptic Function

  2013cites this paper
• Regulation of Ca(V)2 calcium channels by G protein coupled receptors.

  2013cites this paper
• Entrada de calcio inducida por los oligómeros del péptido amiloide en la Enfermedad de Alzheimer

  2013cites this paper
• Establishment of a secondary screening assay for P/Q-type calcium channel blockers.

  2013cites this paper
• Overview: Spatial and Temporal Regulation of Ca 2+ Channels

  2013cites this paper
• Control of low-threshold exocytosis by T-type calcium channels.

  2013cites this paper
• Are unreliable release mechanisms conserved from NMJ to CNS?

  2013cites this paper
• The voltage-gated calcium channel functions as the molecular switch of synaptic transmission.

  2013cites this paper
• Cytotoxicity of Botulinum Neurotoxins Reveals a Direct Role of Syntaxin 1 and SNAP-25 in Neuron Survival

  2013cites this paper
• Modulation of Presynaptic Calcium Channels

  2013influential citation
• The E1015K Variant in the Synprint Region of the CaV2.1 Channel Alters Channel Function and Is Associated with Different Migraine Phenotypes*

  2013cites this paper
• Tracking Ca2+-dependent and Ca2+-independent conformational transitions in syntaxin 1A during exocytosis in neuroendocrine cells

  2013influential citation
• Reciprocal Regulation of Neuronal Calcium Channels by Synaptic Proteins

  2013cites this paper
• Control of CaV2 Calcium Channels and Neurosecretion by Heterotrimeric G Protein Coupled Receptors

  2013cites this paper
• Molecular architecture of Ca2+ channel complexes organized by CaVβ subunits in presynaptic active zones

  2013cites this paper
• Regulation of voltage-gated calcium channels by synaptic proteins.

  2012cites this paper
• Cellular dynamics of voltage-gated calcium channel β subunits

  2012cites this paper
• How do T-type calcium channels control low-threshold exocytosis?

  2012cites this paper
• Cell-specific splicing factors that optimize calcium channel function

  2012cites this paper
• Association analysis of STX1A gene variants in common forms of migraine

  2012cites this paper
• Functional interactions between voltage-gated Ca(2+) channels and Rab3-interacting molecules (RIMs): new insights into stimulus-secretion coupling.

  2012cites this paper
• Gβγ Inhibits Exocytosis via Interaction with Critical Residues on Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein-25

  2012cites this paper
• Calcium around the Golgi apparatus: implications for intracellular membrane trafficking.

  2012cites this paper
• Impairment of Catecholamine Systems during Induction of Long-Term Potentiation at Hippocampal CA1 Synapses in HPC-1/Syntaxin 1A Knock-out Mice

  2012cites this paper
• Physical and functional interaction of the active zone protein CAST/ERC2 and the β-subunit of the voltage-dependent Ca(2+) channel.

  2012cites this paper
• Dual regulation of voltage- and ligand-gated calcium channels by collapsin response mediator protein 2

  2012cites this paper
• A Cav 3 . 2 / Syntaxin-1 A Signaling Complex Controls T-type Channel Activity and Low-threshold Exocytosis *

  2012cites this paper
• Molecular Mechanism of Active Zone Organization at Vertebrate Neuromuscular Junctions

  2012cites this paper
• THE FUNCTIONAL ORGANIZATION OF SYNAPTIC VESICLE POOLS IN A RETINAL BIPOLAR NEURON

  2012cites this paper
• Characterization of the Substituted N-Triazole Oxindole TROX-1, a Small-Molecule, State-Dependent Inhibitor of Cav2 Calcium Channels

  2012cites this paper
• Biomarker-based dissection of neurodegenerative diseases.

  2011cites this paper
• Signaling complexes of voltage-gated calcium channels

  2011cites this paper
• Transportsomes and channelsomes: Are they functional units for physiological responses?

  2011cites this paper
• Syntaxin-1A Interacts with Distinct Domains within Nucleotide-binding Folds of Sulfonylurea Receptor 1 to Inhibit β-Cell ATP-sensitive Potassium Channels*

  2011cites this paper
• Voltage-gated calcium channels.

  2011cites this paper
• Microsoft Word-56059911-file00

  2011cites this paper
• Possible involvement of syntaxin 1A downregulation in the late phase of allodynia induced by peripheral nerve injury.

  2011cites this paper
• Anàlisi genètica i funcional de la migranya hemiplègica i la migranya comuna

  2011cites this paper