Etk, a Btk Family Tyrosine Kinase, Mediates Cellular Transformation by Linking Src to STAT3 Activation

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Molecular and Cellular Biology

• Publication date

  2000-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.20.6.2043-2054.2000PMID 10688651PMCID PMC110821
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells.

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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

  1998cited by this paper
• Stat3 Plays an Important Role in Oncogenic Ros- and Insulin-like Growth Factor I Receptor-induced Anchorage-independent Growth*

  1998cited by this paper
• The G protein G alpha12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain.

  1998cited by this paper
• Tec/Bmx non‐receptor tyrosine kinases are involved in regulation of Rho and serum response factor by Gα12/13

  1998cited by this paper
• Activation of Stat3 by v-Src is through a Ras-independent pathway.

  1998cited by this paper
• Btk function in B cell development and response.

  1998cited by this paper
• STAT3 orchestrates contradictory signals in cytokine‐induced G1 to S cell‐cycle transition

  1998cited by this paper
• Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation

  1998cited by this paper
• Suppression of transforming growth factor-β-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathway

  1998cited by this paper
• Induction of epithelial tubules by growth factor HGF depends on the STAT pathway

  1998cited by this paper
• Stat3 Activation Is Required for Cellular Transformation by v-src

  1998influential reference
• The Bmx tyrosine kinase induces activation of the Stat signaling pathway, which is specifically inhibited by protein kinase Cdelta.

  1997cited by this paper
• Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit

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• Direct stimulation of Bruton's tyrosine kinase by G(q)-protein alpha-subunit.

  1997cited by this paper
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  1997cited by this paper
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• Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.

  1997cited by this paper
• The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28.

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  1997influential reference
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• Src-induced activation of inducible T cell kinase (ITK) requires phosphatidylinositol 3-kinase activity and the Pleckstrin homology domain of inducible T cell kinase.

  1997cited by this paper
• Tec Protein-Tyrosine Kinase is an Effector Molecule of Lyn Protein-Tyrosine Kinase

  1997cited by this paper
• Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases

  1997cited by this paper
• The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3 but not STAT1 homodimer formation.

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• Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases

  1996influential reference
• STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients.

  1996cited by this paper
• Unique signal transduction of Eyk: constitutive stimulation of the JAK‐STAT pathway by an oncogenic receptor‐type tyrosine kinase.

  1996cited by this paper
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  1996cited by this paper
• Differentiation and growth arrest signals are generated through the cytoplasmic region of gp130 that is essential for Stat3 activation.

  1996cited by this paper
• Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.

  1996cited by this paper
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  1996cited by this paper
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• Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain*

  1996cited by this paper
• Activation and association of Stat3 with Src in v-Src-transformed cell lines

  1996influential reference
• Regulation of Btk by Src family tyrosine kinases

  1996cited by this paper
• Regulation of Btk function by a major autophosphorylation site within the SH3 domain.

  1996influential reference
• Tec protein‐tyrosine kinase is an effector molecule of Lyn proteni‐tyroenie kinase

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  1995cited by this paper
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  1995cited by this paper
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