Neurogenic potential of stem/progenitor-like cells in the adult mammalian eye.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Progress in retinal and eye research

• Publication date

  2012-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.preteyeres.2012.02.001PMID 22353284
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Simvastatin improves retinal ganglion cell survival and spatial vision after acute retinal ischemia/reperfusion in mice.

  2011cited by this paper
• In Situ Dividing and Phagocytosing Retinal Microglia Express Nestin, Vimentin, and NG2 In Vivo

  2011influential reference
• DEVELOMENT AND NEUROGENIC POTENTIAL OF MÜLLER GLIAL CELLS IN THE VERTEBRATE RETINA

  2011cited by this paper
• Pigment epithelial cells isolated from human peripheral iridectomies have limited properties of retinal stem cells

  2011cited by this paper
• Age-dependent fate and lineage restriction of single NG2 cells

  2011cited by this paper
• Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6

  2011cited by this paper
• Nestin in gastrointestinal and other cancers: effects on cells and tumor angiogenesis.

  2011cited by this paper
• Nestin Reporter Transgene Labels Multiple Central Nervous System Precursor Cells

  2011cited by this paper
• In vitro differentiation of retinal pigment epithelium from adult retinal stem cells

  2011influential reference
• NG2-glia as multipotent neural stem cells: fact or fantasy?

  2011cited by this paper
• A Common Progenitor for Retinal Astrocytes and Oligodendrocytes

  2010cited by this paper
• Triamcinolone attenuates macrophage/microglia accumulation associated with NMDA-induced RGC death and facilitates survival of Müller stem cell grafts.

  2010cited by this paper
• Adult Ciliary Epithelial Cells, Previously Identified as Retinal Stem Cells with Potential for Retinal Repair, Fail to Differentiate into New Rod Photoreceptors

  2010influential reference
• Nestin Is Essential for Zebrafish Brain and Eye Development through Control of Progenitor Cell Apoptosis

  2010influential reference
• Induced NG2 expressing microglia in the facial motor nucleus after facial nerve axotomy.

  2010cited by this paper
• The Neural Stem/Progenitor Cell Marker Nestin Is Expressed in Proliferative Endothelial Cells, but Not in Mature Vasculature

  2010influential reference
• What determines neurogenic competence in glia?

  2010cited by this paper
• Heterogeneity of Glia in the Retina and Optic Nerve of Birds and Mammals

  2010cited by this paper
• Turning Müller Glia into Neural Progenitors in the Retina

  2010cited by this paper
• Making neurons from mature glia: a far-fetched dream?

  2010cited by this paper
• Structural Remodeling of Fibrous Astrocytes after Axonal Injury

  2010cited by this paper
• Roles of paroxetine and corticosterone on adult mammalian ciliary body cell proliferation.

  2010influential reference
• Nestin expression in human tumors and tumor cell lines.

  2010cited by this paper
• Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

  2010cited by this paper
• Proliferative response of microglia and macrophages in the adult mouse eye after optic nerve lesion.

  2010cited by this paper
• A decade of mammalian retinal stem cell research.

  2010cited by this paper
• Contribution of constitutively proliferating precursor cell subtypes to dentate neurogenesis after cortical infarcts

  2010cited by this paper
• Nestin is essential for mitogen-stimulated proliferation of neural progenitor cells.

  2010influential reference
• Characterization of nestin expression in the spinal cord of GFP transgenic mice after peripheral nerve injury.

  2010cited by this paper
• Regenerative medicine for retinal diseases: activating endogenous repair mechanisms.

  2010cited by this paper
• Nestin, A New Marker, Expressed in Müller Cells Following Retinal Injury

  2010cited by this paper
• Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve.

  2010cited by this paper
• Müller cells in the healthy and diseased retina.

  2010influential reference
• Adult Retinal Stem Cells Revisited

  2010cited by this paper
• Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex

  2010cited by this paper
• Astrocytes Express N-Methyl-D-Aspartate Receptor Subunits in Development, Ischemia and Post-Ischemia

  2010cited by this paper
• The myeloid cells of the central nervous system parenchyma

  2010cited by this paper
• NG2 cells: Properties, progeny and origin.

  2010cited by this paper
• Cellular signaling and factors involved in Müller cell gliosis: neuroprotective and detrimental effects.

  2009cited by this paper
• Glutamate, excitotoxicity, and programmed cell death in Parkinson disease.

  2009cited by this paper
• Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

  2009cited by this paper
• ctivation of retinal stem cells in the proliferating marginal region of RCS rats uring development of retinitis pigmentosa

  2009cited by this paper
• Müller cell activation, proliferation and migration following laser injury

  2009cited by this paper
• Distribution of Müller stem cells within the neural retina: evidence for the existence of a ciliary margin-like zone in the adult human eye.

  2009cited by this paper
• Optic nerve lesion increases cell proliferation and nestin expression in the adult mouse eye in vivo.

  2009influential reference
• Maximizing Functional Photoreceptor Differentiation From Adult Human Retinal Stem Cells

  2009influential reference
• Nestin-positive microglia in adult rat cerebral cortex.

  2009influential reference
• Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells

  2009influential reference
• Stem/progenitor cells: a potential source of retina-specific cells for retinal repair.

  2009influential reference
• A comparison of epithelial and neural properties in progenitor cells derived from the adult human ciliary body and brain.

  2009influential reference
• Adult hippocampal neurogenesis: regulation, functional implications, and contribution to disease pathology.

  2009cited by this paper
• Neural regeneration and cell replacement: a view from the eye.

  2008cited by this paper
• Accumulation of Macrophage-Like Cells Expressing NG2 Proteoglycan and Iba1 in Ischemic Core of Rat Brain after Transient Middle Cerebral Artery Occlusion

  2008cited by this paper
• Time course profiling of the retinal transcriptome after optic nerve transection and optic nerve crush

  2008cited by this paper
• Microtubule-associated protein 2-positive cells derived from microglia possess properties of functional neurons.

  2008cited by this paper
• The ameboid phenotype of NG2 (+) cells in the region of apoptotic dentate granule neurons in trimethyltin intoxicated mice shares antigen properties with microglia/macrophages

  2008cited by this paper
• Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

  2008cited by this paper
• Chondroitin Sulfate Proteoglycans and Microglia Prevent Migration and Integration of Grafted Müller Stem Cells into Degenerating Retina

  2008cited by this paper
• Gradual morphogenesis of retinal neurons in the peripheral retinal margin of adult monkeys and humans

  2008cited by this paper
• Nuclear migration during retinal development.

  2008cited by this paper
• Cell-cycle-specific nestin expression coordinates with morphological changes in embryonic cortical neural progenitors

  2008influential reference
• The transcriptome of retinal Müller glial cells

  2008influential reference
• Nestin expression in repopulating mesangial cells promotes their proliferation

  2008cited by this paper
• Differential turnover rates of monocyte‐derived cells in varied ocular tissue microenvironments

  2008cited by this paper
• Nestin in central nervous system cells

  2008cited by this paper
• PDGFRA/NG2 glia generate myelinating oligodendrocytes and piriform projection neurons in adult mice

  2008cited by this paper
• Neuronal stem/progenitor cells in the vertebrate eye

  2008cited by this paper
• Stimulation of neural regeneration in the mouse retina

  2008influential reference
• Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury.

  2008influential reference
• Statins modulate heat shock protein expression and enhance retinal ganglion cell survival after transient retinal ischemia/reperfusion in vivo.

  2008influential reference
• Induction of retinal pigment epithelium properties in ciliary margin progenitor cells

  2008influential reference
• Neural progenitor potential in cultured Müller glia: effects of passaging and exogenous growth factor exposure.

  2008cited by this paper
• Preferential regeneration of photoreceptor from Müller glia after retinal degeneration in adult rat.

  2008influential reference
• Hypoxia-ischemia and retinal ganglion cell damage

  2008cited by this paper
• Mature retinal pigment epithelium cells are retained in the cell cycle and proliferate in vivo

  2008influential reference
• Expression of intermediate filament nestin in blood vessels of neural and non-neural tissues.

  2008cited by this paper
• Human Müller stem cell (MIO-M1) transplantation in a rat model of glaucoma: survival, differentiation, and integration.

  2008cited by this paper
• alpha-Aminoadipate induces progenitor cell properties of Müller glia in adult mice.

  2008influential reference
• Multi‐directional differentiation of doublecortin‐ and NG2‐immunopositive progenitor cells in the adult rat neocortex in vivo

  2007cited by this paper
• Genomic and proteomic microglial profiling: pathways for neuroprotective inflammatory responses following nerve fragment clearance and activation

  2007cited by this paper
• Microglia: active sensor and versatile effector cells in the normal and pathologic brain

  2007cited by this paper
• Fibroblast growth factor and epidermal growth factor differently affect differentiation of murine retinal stem cells in vitro.

  2007influential reference
• Müller cells are living optical fibers in the vertebrate retina

  2007cited by this paper
• Stem cell therapy and the retina

  2007cited by this paper
• Müller cells as players in retinal degeneration and edema

  2007cited by this paper
• Multipotent cells from mammalian iris pigment epithelium.

  2007influential reference
• Sonic hedgehog promotes stem-cell potential of Müller glia in the mammalian retina.

  2007influential reference
• MIO‐M1 Cells and Similar Müller Glial Cell Lines Derived from Adult Human Retina Exhibit Neural Stem Cell Characteristics

  2007cited by this paper
• Neurotrophic factors and neuronal death.

  2007cited by this paper
• MEK mediates in vitro neural transdifferentiation of the adult newt retinal pigment epithelium cells: Is FGF2 an induction factor?

  2007cited by this paper
• Characteristics of progenitor cells derived from adult ciliary body in mouse, rat, and human eyes.

  2007influential reference
• Proliferation and expression of progenitor and mature retinal phenotypes in the adult mammalian ciliary body after retinal ganglion cell injury.

  2007influential reference
• Regeneration of Inner Retinal Neurons after Intravitreal Injection of Ouabain in Zebrafish

  2007cited by this paper
• Retinal ischemia and cell proliferation in the rat: the role of soluble mitogens

  2007cited by this paper
• Reactive changes of retinal astrocytes and Müller glial cells in kainate‐induced neuroexcitotoxicity

  2007influential reference
• Isolation of retinal progenitor and stem cells from the porcine eye

  2007cited by this paper
• Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma

  2007cited by this paper
• Late-Stage Neuronal Progenitors in the Retina Are Radial Müller Glia That Function as Retinal Stem Cells

  2007influential reference
• Production of neurospheres from mammalian Müller cells in culture.

  2007cited by this paper
• Comparative Analysis of Progenitor Cells Isolated from the Iris, Pars Plana, and Ciliary Body of the Adult Porcine Eye

  2007influential reference

• Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma.

  2023cites this paper
• Application of low-intensity pulsed ultrasound on tissue resident stem cells: Potential for ophthalmic diseases

  2023cites this paper
• Integrative Single‐Cell Transcriptomics and Epigenomics Mapping of the Fetal Retina Developmental Dynamics

  2023cites this paper
• Primary Cell Cultures to Study the Regeneration Potential of Murine Müller Glia after MicroRNA Treatment.

  2022cites this paper
• Pigment Epithelia of the Eye: Cell-Type Conversion in Regeneration and Disease

  2022cites this paper
• Cell Sources for Retinal Regeneration: Implication for Data Translation in Biomedicine of the Eye

  2022cites this paper
• Glucocorticoid agonists enhance retinal stem cell self-renewal and proliferation

  2021cites this paper
• Activation of adult mammalian retinal stem cells in vivo via antagonism of BMP and sFRP2

  2021cites this paper
• Retinal Stem Cell ‘Retirement Plans’: Growth, Regulation and Species Adaptations in the Retinal Ciliary Marginal Zone

  2021cites this paper
• Retinal Ganglion Cell Transplantation: Approaches for Overcoming Challenges to Functional Integration

  2021cites this paper
• Potential Endogenous Cell Sources for Retinal Regeneration in Vertebrates and Humans: Progenitor Traits and Specialization

  2020cites this paper
• Bone marrow mesenchymal stem cells modified by angiogenin‐1 promotes tissue repair in mice with oxygen‐induced retinopathy of prematurity by promoting retinal stem cell proliferation and differentiation

  2019cites this paper
• Adult Stem Cells, Tools for Repairing the Retina

  2019cites this paper
• The peripheral eye: A neurogenic area with potential to treat retinal pathologies?

  2019influential citation
• Regulation of neuronal and photoreceptor cell differentiation by Wnt signaling from iris-derived stem/progenitor cells of the chick in flat vs. Matrigel-embedding cultures.

  2019cites this paper
• Characterization of Stem and proliferating cells on the retina and lens of loach Misgurnus anguillicaudatus.

  2019cites this paper
• Chapter 4 Reactive Muller Glia as Potential Retinal Progenitors

  2018cites this paper
• Proliferative Cells Isolated from the Adult Human Peripheral Retina only Transiently Upregulate Key Retinal Markers upon Induced Differentiation

  2018cites this paper
• Müller glia and phagocytosis of cell debris in retinal tissue

  2017cites this paper
• A novel culture method reveals unique neural stem/progenitors in mature porcine iris tissues that differentiate into neuronal and rod photoreceptor-like cells.

  2017cites this paper
• Chapter 20 – Mobilizing Endogenous Stem Cells for Retinal Repair

  2016cites this paper
• Identification of Radial Glia Progenitors in the Developing and Adult Retina of Sharks

  2016influential citation
• miR-124-9-9* Potentiates Ascl1-Induced Reprogramming of Cultured M€uller Glia

  2016cites this paper
• Glia-neuron interactions in the mammalian retina.

  2016cites this paper
• Clinical Trials in Retinal Dystrophies

  2016cites this paper
• Efficient Production of Photoreceptor Precursor Cells from Human Embryonic Stem Cells.

  2016cites this paper
• MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors

  2015cites this paper
• Lgr5+ amacrine cells possess regenerative potential in the retina of adult mice

  2015cites this paper
• Enhanced Functional Integration of Human Photoreceptor Precursors into Human and Rodent Retina in an Ex Vivo Retinal Explant Model System

  2015cites this paper
• Stem cell approaches to glaucoma: from aqueous outflow modulation to retinal neuroprotection.

  2015cites this paper
• Telocytes in regenerative medicine

  2015cites this paper
• Doublecortin is widely expressed in the developing and adult retina of sharks.

  2015cites this paper
• Stemistry: the control of stem cells in situ using chemistry.

  2015cites this paper
• PEDF counteracts DL-α-aminoadipate toxicity and rescues gliotoxic damages in RPE-free chicken retinal explants.

  2015cites this paper
• 61 – Neuroprotection and Neurorepair

  2015cites this paper
• The extracellular matrix compartment of neural stem and glial progenitor cells

  2015cites this paper
• 63 – Stem Cells: A Future Glaucoma Therapy?

  2014cites this paper
• Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

  2014cites this paper
• Renin–angiotensin system regulates neurodegeneration in a mouse model of normal tension glaucoma

  2014cites this paper
• Mobilizing endogenous stem cells for retinal repair.

  2014cites this paper
• A novel mode of retinal regeneration: the merit of a new Xenopus model

  2014cites this paper
• Survival and Migration of Pre-induced Adult Human Peripheral Blood Mononuclear Cells in Retinal Degeneration Slow (rds) Mice Three Months After Subretinal Transplantation

  2014cites this paper
• Immediate differentiation of neuronal cells from stem/progenitor-like cells in the avian iris tissues.

  2014cites this paper
• Müller glia: Stem cells for generation and regeneration of retinal neurons in teleost fish.

  2014cites this paper
• Potential of Müller Glia and Stem/Progenitor Cells to Regenerate Retinal Tissue

  2014cites this paper
• Endogenous IgG affects the cell biology of RPE cells and involves the TLR4 pathway.

  2013cites this paper
• Development of human embryonic stem cell therapies for age-related macular degeneration.

  2013cites this paper
• Glutamate-induced epigenetic and morphological changes allow rat Müller cell dedifferentiation but not further acquisition of a photoreceptor phenotype.

  2013cites this paper
• Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytes

  2013cites this paper
• Reactive Muller Glia as Potential Retinal Progenitors

  2013cites this paper
• Differentiation of Human Embryonic Stem Cells Using Size-Controlled Embryoid Bodies and Negative Cell Selection in the Production of Photoreceptor Precursor Cells

  2013cites this paper
• Telocytes and stem cells in limbus and uvea of mouse eye

  2013cites this paper
• Adult ciliary epithelial stem cells generate functional neurons and differentiate into both early and late born retinal neurons under non-cell autonomous influences

  2013cites this paper
• Does the Adult Human Ciliary Body Epithelium Contain “True” Retinal Stem Cells?

  2013cites this paper
• The metalloproteinase inhibitor Reck is essential for zebrafish DRG development

  2012cites this paper