Fibroblast growth factor 7: an inhibitor of phosphate transport derived from oncogenic osteomalacia-causing tumors.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Clinical Endocrinology and Metabolism

• Publication date

  2005-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/JC.2004-0357PMID 15562028
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MEPE has the properties of an osteoblastic phosphatonin and minhibin.

  2004cited by this paper
• Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis.

  2004cited by this paper
• FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type IIa.

  2004cited by this paper
• Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism.

  2004cited by this paper
• Disorders of renal tubular phosphate transport.

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  2003cited by this paper
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• Fibroblast Growth Factor 23: A New Clinical Marker for Oncogenic Osteomalacia

  2003cited by this paper
• Targeted Disruption of the Osteoblast/Osteocyte Factor 45 Gene (OF45) Results in Increased Bone Formation and Bone Mass*

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• Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.

  2003cited by this paper
• Serum FGF23 Levels in Normal and Disordered Phosphorus Homeostasis

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• Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.

  2003cited by this paper
• Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent.

  2003cited by this paper
• Oncogenic osteomalacia--a complex dance of factors.

  2003cited by this paper
• Tumors Associated With Oncogenic Osteomalacia Express Genes Important in Bone and Mineral Metabolism

  2002cited by this paper
• FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease.

  2002cited by this paper
• Fibroblast Growth Factor (FGF)-23 Inhibits Renal Phosphate Reabsorption by Activation of the Mitogen-activated Protein Kinase Pathway*

  2002cited by this paper
• FGF-23 inhibits renal tubular phosphate transport and is a PHEX substrate.

  2001cited by this paper
• Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

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• Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23.

  2001cited by this paper
• Recent Developments in the Immunology of Inflammatory Bowel Disease

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• Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair.

  2000cited by this paper
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• Phosphaturic Mesenchymal Tumor-Induced Rickets

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• Role of tumour markers, cytogenetics.

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• Phosphate in Physiological and Pathological Mineralization: Important yet Often Unheeded

  2025cites this paper
• More on Acquired Osteomalacia and Autoantibodies against PHEX. Reply.

  2025cites this paper
• Exploring the Role of FGF7 in Tumor-Induced Osteomalacia. Clinic–Pathologic Analysis in a Patient with a Sino-Nasal Phosphaturic Mesenchymal Tumor

  2025cites this paper
• The Intricacies of Renal Phosphate Reabsorption—An Overview

  2024cites this paper
• Preoperative evaluation and orthopedic surgical strategies for tumor-induced osteomalacia

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• Tumor-Induced Osteomalacia: A Systematic Clinical Review of 895 Cases

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• Phosphatonins: From Discovery to Therapeutics.

  2022cites this paper
• TUMOR-INDUCED OSTEOMALACIA: A COMPREHENSIVE REVIEW.

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• Tumorlokalisation und Therapie der onkogenen Osteomalazie

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• Post-Mortem Detection of SARS-CoV-2 RNA in Long-Buried Lung Samples

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• Disorders of Mineral Metabolism: Normal Homeostasis

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• Novel mineral regulatory pathways in ovine pregnancy: I. phosphate, klotho signaling, and sodium-dependent phosphate transporters

  2021cites this paper
• Hyperphosphatemia with elevated serum PTH and FGF23, reduced 1,25(OH)2D and normal FGF7 concentrations characterize patients with CKD

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• Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals.

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• Phosphatonins

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• The Causes of Hypo- and Hyperphosphatemia in Humans

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• Phosphorus homeostasis and related disorders

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• Hyperphosphatemia with low FGF7 and normal FGF23 and sFRP4 levels in the circulation characterizes pediatric hypophosphatasia.

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• New Therapies for Hypophosphatemia-Related to FGF23 Excess

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• FGF23 and Bone and Mineral Metabolism.

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• Tumor-induced osteomalacia: experience from three tertiary care centers in India

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• Mechanisms of phosphate transport

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• FGF23 and Associated Disorders of Phosphate Wasting.

  2019cites this paper
• Mechanisms of intestinal phosphate absorption and the effect of diet-induced iron deficiency on phosphate homeostasis

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• Hereditary hypophosphatemic rickets with hypercalciuria: pathophysiology, clinical presentation, diagnosis and therapy

  2018cites this paper
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  2018cites this paper
• Histopathological and genetic review of phosphaturic mesenchymal tumours, mixed connective tissue variant

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• Clinical Disorders of Phosphate Homeostasis

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• Osteomalacia, renal Fanconi syndrome, and bone tumor

  2018cites this paper
• Reports of 17 Chinese patients with tumor-induced osteomalacia

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• Tumour-induced osteomalacia

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• Tumor-induced osteomalacia

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• Tumor induced osteomalacia: associated with elevated circulating levels of fibroblast growth factor-7 in addition to fibroblast growth factor-23.

  2016cites this paper
• Phosphate homeostasis and genetic mutations of familial hypophosphatemic rickets

  2015cites this paper
• Surgical treatment of tumor-induced osteomalacia: a retrospective review of 40 cases with extremity tumors

  2015cites this paper
• Physiology of the developing kidney: Disorders and therapy of calcium and phosphorous homeostasis

  2015cites this paper
• Phosphate Homeostasis and Metabolic Bone Disease

  2014cites this paper
• Diagnostic Modalities for FGF23-Producing Tumors in Patients with Tumor-Induced Osteomalacia

  2014cites this paper
• Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia.

  2014cites this paper
• Primary Disorders of Phosphate Metabolism

  2014cites this paper
• Renal handling of phosphate and sulfate.

  2014cites this paper
• Renal phosphate handling: Physiology

  2013cites this paper
• The changing face of hypophosphatemic disorders in the FGF-23 era.

  2013cites this paper
• Insights from genetic disorders of phosphate homeostasis.

  2013cites this paper
• Clinical Disturbances of Phosphate Homeostasis

  2013cites this paper
• Postnatal Renal Development

  2013cites this paper
• Clinical Aspects of Fibroblast Growth Factor 23

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• Biological Activities of Phosphocitrate: A Potential Meniscal Protective Agent

  2013cites this paper
• Dietary phosphorus sources and their acute effects on mineral metabolism in healthy women

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• Rickets: The Skeletal Disorders of Impaired Calcium or Phosphate Availability

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• [Oncogenic osteomalacia and its symptoms: hypophosphatemia, bone pain and pathological fractures].

  2012influential citation
• Evidence for FGF23 involvement in a bone-kidney axis regulating bone mineralization and systemic phosphate and vitamin D homeostasis.

  2012cites this paper
• Molecular Mechanisms of Intestinal Transport of Calcium, Phosphate, and Magnesium

  2012cites this paper
• Regulation and function of the FGF23/klotho endocrine pathways.

  2012cites this paper
• Phosphate Homeostasis Regulatory Mechanisms

  2012cites this paper
• FGF23 and syndromes of abnormal renal phosphate handling.

  2012cites this paper
• Phosphorus and Calcium Metabolism Disorders Associated with Chronic Kidney Disease Stage III-IV (Systematic Review and Meta-Analysis)

  2012cites this paper
• Bilateral Subtrochanteric Fractures in Tumour-Induced Osteomalacia Caused by a Nasal Haemangiopericytoma

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• Reno-endocrinal disorders: A basic understanding of the molecular genetics

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• Hereditary Tubular Disorders of Mineral Handling

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• Regulation of pathways involved in intestinal phosphate transport

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• Tumor-induced osteomalacia: a single center experience.

  2011cites this paper
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• Matrix extracellular phosphoglycoprotein (MEPE): a putative phosphatonin

  2011influential citation
• O OSSO COMO ÓRGÃO ENDÓCRINO

  2011cites this paper
• Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

  2011cites this paper
• Minireview: fibroblast growth factor 23 in phosphate homeostasis and bone metabolism.

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  2010cites this paper
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• Hereditary disorders of renal phosphate wasting

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• Osteomalacia inducida por tumor Tumor-induced osteomalacia

  2010cites this paper
• Transgenic mice overexpressing secreted frizzled-related proteins (sFRP)4 under the control of serum amyloid P promoter exhibit low bone mass but did not result in disturbed phosphate homeostasis.

  2010cites this paper
• Disorders of Phosphorus Homeostasis

  2010cites this paper
• FGF23: Phosphate metabolism and beyond

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  2010influential citation
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  2009cites this paper
• Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia

  2009cites this paper
• GALNT3, a gene associated with hyperphosphatemic familial tumoral calcinosis, is transcriptionally regulated by extracellular phosphate and modulates matrix metalloproteinase activity.

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• Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature.

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