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Natural Compounds and Their Role in Autophagic Cell Signaling Pathways

A. Rasul,T. Ma

Published 2013 in Unknown venue

ABSTRACT

The term autophagy (from the Greek, auto – oneself, phagy to eat or autophagy-self eating) was first coined for structures that were observed under an electron microscope and that were consisted of single-or double-membrane lysosomal-derived vesicles containing cytoplasmic particles including organelles during various stages of disintegration [1,2]. Autophagic cell death or autophagy is a type of cell death that occurs in the absence of chromatin condensation but is associated with the massive autophagic vacuolization of the cytoplasm [3]. Autophagy is the process by which cells recycle their own nonessential, redundant, and damaged organelles and macromolecular components. Autophagy also plays its role in the suppression of tumor growth, deletion of toxic misfolded proteins, elimination of intracellular microor‐ ganisms, and pathogenesis of several diseases such as cancer and muscular disorders [4-6].

PUBLICATION RECORD

  • Publication year

    2013

  • Venue

    Unknown venue

  • Publication date

    2013-04-17

  • Fields of study

    Biology, Medicine, Chemistry

  • Identifiers
    DOI 10.5772/55447
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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