Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Free radical research

• Publication date

  2008-01-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1080/10715760802112791PMID 18484413
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2006cited by this paper
• Autophagy: role in surviving environmental stress.

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  2006cited by this paper
• Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress.

  2006cited by this paper
• Cross Talk between Reactive Nitrogen and Oxygen Species during the Hypersensitive Disease Resistance Response1

  2006cited by this paper
• Oxidative Stress and Autophagy

  2006cited by this paper
• The contribution of DNA repair and antioxidants in determining cell type-specific resistance to oxidative stress

  2006cited by this paper
• Apoptosis in mosquito midgut epithelia associated with West Nile virus infection

  2006cited by this paper
• Cell culture models of oxidative stress and injury in the central nervous system.

  2005cited by this paper
• Autophagy in innate and adaptive immunity.

  2005cited by this paper
• Production of nitric oxide-derived reactive nitrogen species in human oral cavity and their scavenging by salivary redox components

  2005influential reference
• Caspase-independent death of Leber’s hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G

  2005cited by this paper
• Overexpression of Manganese Superoxide Dismutase Promotes the Survival of Prostate Cancer Cells Exposed to Hyperthermia

  2004cited by this paper
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  2004cited by this paper
• Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages.

  2004cited by this paper
• Apoptosis, autophagy, and more.

  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
• The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo.

  2002cited by this paper
• Obesity, aerobic exercise, and vascular disease: the role of oxidant stress.

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• On the origin, evolution, and nature of programmed cell death: a timeline of four billion years

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• Growth phase-dependent expression of ICAD-L/DFF45 modulates the pattern of apoptosis in human colonic cancer cells.

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• Free radicals in the physiological control of cell function.

  2002cited by this paper
• Free Radical Scavenging Properties of Sulfinpyrazone

  2002influential reference
• Oxidative Stress, Mitochondrial DNA Mutation, and Impairment of Antioxidant Enzymes in Aging 1

  2002influential reference
• Beclin–phosphatidylinositol 3‐kinase complex functions at the trans‐Golgi network

  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
• Interactions of oxidants with vascular signaling systems.

  2000cited by this paper
• Apoptosis in human disease: a new skin for the old ceremony?

  1999cited by this paper
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  1998cited by this paper
• The Multiplex Function of Nitric Oxide in (Auto)immunity

  1998cited by this paper
• The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.

  1998cited by this paper
• BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells.

  1996cited by this paper
• Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles.

  1995cited by this paper
• Reaction of nitric oxide with hydrogen peroxide to produce potentially cytotoxic singlet oxygen as a model for nitric oxide‐mediated killing

  1993cited by this paper
• The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: mode of action.

  1992cited by this paper
• Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit.

  1989cited by this paper

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  2022cites this paper
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  2012cites this paper
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