The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Genes & Development

• Publication date

  1994-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.8.11.1270PMID 7926730
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intracellular association of the protein product of the c-myc oncogene with the TATA-binding protein

  1994cited by this paper
• An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types.

  1993cited by this paper
• Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein.

  1993cited by this paper
• Physical interaction of the retinoblastoma protein with human D cyclins.

  1993cited by this paper
• Functional interactions of the retinoblastoma protein with mammalian D-type cyclins.

  1993cited by this paper
• Physical and functional interaction between WT1 and p53 proteins.

  1993cited by this paper
• Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4.

  1993cited by this paper
• The Rb gene suppresses the growth of normal cells.

  1993cited by this paper
• Bone morphogenetic protein 2 transiently enhances expression of a gene, Id (inhibitor of differentiation), encoding a helix-loop-helix molecule in osteoblast-like cells.

  1993cited by this paper
• A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle.

  1993cited by this paper
• The loop region of the helix-loop-helix protein Id1 is critical for its dominant negative activity

  1993cited by this paper
• Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation.

  1993cited by this paper
• Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties.

  1992cited by this paper
• Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins.

  1992cited by this paper
• A cDNA encoding a pRB-binding protein with properties of the transcription factor E2F.

  1992cited by this paper
• Expression of helix‐loop‐helix regulatory genes during differentiation of mouse osteoblastic cells

  1992cited by this paper
• Id gene expression and its suppression by 1,25-dihydroxyvitamin D3 in rat osteoblastic osteosarcoma cells.

  1992cited by this paper
• A human Id-like helix-loop-helix protein expressed during early development.

  1992cited by this paper
• Identification of DNA-replicating lymphocyte subsets using a new method to label the bromo-deoxyuridine incorporated into the DNA.

  1992cited by this paper
• Inhibition of myeloid differentiation by the helix-loop-helix protein Id.

  1992cited by this paper
• Functional analysis at the Cys706 residue of the retinoblastoma protein.

  1992cited by this paper
• Regulation of retinoblastoma protein functions by ectopic expression of human cyclins.

  1992cited by this paper
• Adenovirus E1A targets key regulators of cell proliferation.

  1992cited by this paper
• Mutually exclusive expression of a helix‐loop‐helix gene and N‐myc in human neuroblastomas and in normal development.

  1992cited by this paper
• Regulation of muscle cell growth and differentiation by the MyoD family of helix-loop-helix proteins.

  1992cited by this paper
• Identification of a growth suppression domain within the retinoblastoma gene product.

  1992cited by this paper
• Transforming growth factor beta induces myoblast differentiation in the presence of mitogens.

  1992cited by this paper
• An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.

  1991cited by this paper
• Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

  1991cited by this paper
• Tumor suppressor genes.

  1991cited by this paper
• Tumor suppressor genes.

  1991cited by this paper
• The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle.

  1991cited by this paper
• The E2F transcription factor is a cellular target for the RB protein.

  1991cited by this paper
• Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins

  1991cited by this paper
• The retinoblastoma protein is phosphorylated on multiple sites by human cdc2.

  1991cited by this paper
• Repression of immunoglobulin enhancers by the helix-loop-helix protein Id: implications for B-lymphoid-cell development

  1991cited by this paper
• Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product.

  1991cited by this paper
• MyoD induces growth arrest independent of differentiation in normal and transformed cells.

  1990cited by this paper
• The protein Id: a negative regulator of helix-loop-helix DNA binding proteins.

  1990cited by this paper
• The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation.

  1990cited by this paper
• Genetic mechanisms of tumor suppression by the human p53 gene

  1990cited by this paper
• The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.

  1990cited by this paper
• C-terminal truncation of the retinoblastoma gene product leads to functional inactivation.

  1990cited by this paper
• Suppression of human colorectal carcinoma cell growth by wild-type p53.

  1990cited by this paper
• Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains.

  1990cited by this paper
• Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

  1990cited by this paper
• A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding.

  1990cited by this paper
• p53 functions as a cell cycle control protein in osteosarcomas

  1990cited by this paper
• G1 events and regulation of cell proliferation.

  1989cited by this paper
• Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

  1989cited by this paper
• Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence.

  1989cited by this paper
• A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins.

  1989cited by this paper
• The retinoblastoma protein is phosphorylated during specific phases of the cell cycle.

  1989cited by this paper
• MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer.

  1989cited by this paper
• SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.

  1988cited by this paper
• Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

  1988cited by this paper
• MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts.

  1988cited by this paper
• A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions.

  1988cited by this paper
• Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.

  1988cited by this paper
• High-efficiency transformation of mammalian cells by plasmid DNA.

  1987cited by this paper
• The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity

  1987cited by this paper
• Human retinoblastoma susceptibility gene: cloning, identification, and sequence

  1987cited by this paper
• Interaction of retroviral oncogenes with the differentiation program of myogenic cells.

  1987cited by this paper
• The biology of cell reproduction

  1985cited by this paper
• Pathologic Basis of Disease

  1974cited by this paper

• Integrative analysis of T cell-associated markers in Ewing sarcoma reveals prognostic signatures and immune dynamics

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• NeuroD 2/6 regulate expression balance of transcription factors controlling neurocortical cytoarchitecture

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• Retinoblastoma Protein Is Required for Epstein-Barr Virus Replication in Differentiated Epithelia

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• Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies

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• ID1 and CEBPA coordinate epidermal progenitor cell differentiation

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• Identifying General Tumor and Specific Lung Cancer Biomarkers by Transcriptomic Analysis

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• Inhibitor of DNA binding/differentiation proteins as IDs for Pancreatic cancer: Role in pancreatic cancer initiation, development and prognosis.

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• The effects of superparamagnetic iron oxide nanoparticle exposure on gene expression patterns in the neural stem cells under magnetic field

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