Bioactives from microalgal dinoflagellates.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biotechnology Advances

• Publication date

  2012-11-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.biotechadv.2012.07.005PMID 22884890
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Design of raceway ponds for producing microalgae

  2012cited by this paper
• Novel toxins produced by the dinoflagellate Karenia brevisulcata

  2012cited by this paper
• Shear‐induced changes in membrane fluidity during culture of a fragile dinoflagellate microalga

  2012cited by this paper
• Improving photosynthesis and metabolic networks for the competitive production of phototroph-derived biofuels.

  2012cited by this paper
• DEVELOPMENT OF A CHEMILUMINESCENT ELISA FOR DETERMINING OKADAIC ACID IN SHELLFISH

  2012cited by this paper
• EFFECTS OF HIGH PRESSURE IN THE ARMORED DINOFLAGELLATE SCRIPPSIELLA HEXAPRAECINGULA (PERIDINIALES, DINOPHYCEAE): CHANGES IN THECAL PLATE PATTERN AND MICROTUBULE ASSEMBLY 1

  2012cited by this paper
• Advances in genetic engineering of marine algae.

  2012cited by this paper
• On the origins and biosynthesis of tetrodotoxin.

  2011cited by this paper
• Enzyme-linked immunosorbent assay for okadaic acid: investigation of analytical conditions and sample matrix on assay performance.

  2011cited by this paper
• Immunoregulatory potential of marine algal toxins yessotoxin and okadaic acid in mouse T lymphocyte cell line EL-4.

  2011cited by this paper
• A review on the effects of environmental conditions on growth and toxin production of Ostreopsis ovata.

  2011cited by this paper
• Development of an oligonucleotide microarray for the detection and monitoring of marine dinoflagellates.

  2011cited by this paper
• Osmotic stress triggers toxin production by the dinoflagellate Karenia brevis

  2011cited by this paper
• Genomic understanding of dinoflagellates.

  2011cited by this paper
• AKAP Phosphatase Complexes in the Heart

  2011cited by this paper
• Carboxymethyl cellulose and Pluronic F68 protect the dinoflagellate Protoceratium reticulatum against shear-associated damage

  2011influential reference
• Micronucleus assays in rodent tissues other than bone marrow.

  2011cited by this paper
• Dinoflagellate genome evolution.

  2011cited by this paper
• Modifications of the metabolic pathways of lipid and triacylglycerol production in microalgae

  2011cited by this paper
• Complete 13C-labeling pattern of yessotoxin a marine ladder-frame polyether

  2011cited by this paper
• Comparative Genomic and Transcriptomic Characterization of the Toxigenic Marine Dinoflagellate Alexandrium ostenfeldii

  2011cited by this paper
• Metabolic engineering of algae for fourth generation biofuels production

  2011cited by this paper
• Photobioreactor scale-up for a shear-sensitive dinoflagellate microalga

  2011influential reference
• Genetic algorithm-based medium optimization for a toxic dinoflagellate microalga

  2011cited by this paper
• Decoding algal genomes: tracing back the history of photosynthetic life on Earth.

  2011cited by this paper
• Biotechnological production of lutein and its applications

  2010influential reference
• Growth and toxin production of tropical Alexandrium minutum Halim (Dinophyceae) under various nitrogen to phosphorus ratios

  2010cited by this paper
• Growth and toxin production in the ciguatera-causing dinoflagellate Gambierdiscus polynesiensis (Dinophyceae) in culture.

  2010cited by this paper
• Using the molecular toolbox to compare harmful algal blooms in upwelling systems

  2010cited by this paper
• Spliced leader–based metatranscriptomic analyses lead to recognition of hidden genomic features in dinoflagellates

  2010cited by this paper
• Effects of environmental regimens on the toxin profile of Alexandrium ostenfeldii

  2010cited by this paper
• Genetic Engineering of Algae for Enhanced Biofuel Production

  2010cited by this paper
• Comparison of analytical tools and biological assays for detection of paralytic shellfish poisoning toxins

  2010cited by this paper
• Culture of dinoflagellates in a fed-batch and continuous stirred-tank photobioreactors: Growth, oxidative stress and toxin production

  2010cited by this paper
• Biosynthesis of toxic naturally-occurring seafood contaminants.

  2010cited by this paper
• Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates

  2010influential reference
• Characterization and Localization of a Hybrid Non-ribosomal Peptide Synthetase and Polyketide Synthase Gene from the Toxic Dinoflagellate Karenia brevis

  2010cited by this paper
• Total Synthesis of Hemibrevetoxin B and (7aα)-epi-Hemibrevetoxin B

  2010cited by this paper
• Polyketides from marine dinoflagellates of the genus Prorocentrum, biosynthetic origin and bioactivity of their okadaic acid analogues.

  2010influential reference
• Operational application of a rapid antibody-based detection assay for first line screening of paralytic shellfish toxins in shellfish

  2010cited by this paper
• Macronutrients requirements of the dinoflagellate Protoceratium reticulatum.

  2009cited by this paper
• Causes of shear sensitivity of the toxic dinoflagellate Protoceratium reticulatum

  2009cited by this paper
• Multiple simultaneous detection of Harmful Algal Blooms (HABs) through a high throughput bead array technology, with potential use in phytoplankton community analysis.

  2009cited by this paper
• Crypthecodinium cohnii with emphasis on DHA production: a review

  2009cited by this paper
• Approaches to monitoring, control and management of harmful algal blooms (HABs).

  2009cited by this paper
• Enhancement of lipid production using biochemical, genetic and transcription factor engineering approaches.

  2009cited by this paper
• Recent trends in paralytic shellfish toxins in Puget Sound, relationships to climate, and capacity for prediction of toxic events

  2009cited by this paper
• Okadaic acid promotes angiogenesis via activation of hypoxia-inducible factor-1.

  2009cited by this paper
• Cloning and analysis of PKS gene from Prorocentrum lima

  2009cited by this paper
• A renaissance in marine pharmacology: from preclinical curiosity to clinical reality.

  2009cited by this paper
• Total synthesis and biological evaluation of amphidinolide V and analogues.

  2009cited by this paper
• Critical analysis of engineering aspects of shaken flask bioreactors

  2009cited by this paper
• Axenic Culture of the Heterotrophic Dinoflagellate Pfiesteria shumwayae in a Semi‐Defined Medium

  2009cited by this paper
• Monoclonal antibody against the surface of Alexandrium minutum used in a whole-cell ELISA

  2009cited by this paper
• Marine natural products.

  2009cited by this paper
• Neurotoxins from Marine Dinoflagellates: A Brief Review

  2008cited by this paper
• Synthetic studies on maitotoxin. 2. Stereoselective synthesis of the WXYZA'-ring system.

  2008cited by this paper
• Synthetic Studies on Maitotoxin. Part 1. Stereoselective Synthesis of the C′D′E′F′‐Ring System Having a Side Chain.

  2008cited by this paper
• Mixotrophy, a major mode of nutrition for harmful algal species in eutrophic waters

  2008cited by this paper
• Impacts of climate variability and future climate change on harmful algal blooms and human health

  2008cited by this paper
• Nuclear Genome Sequence Survey of the Dinoflagellate Heterocapsa triquetra

  2008cited by this paper
• Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates

  2008cited by this paper
• Relationships among water column toxins, cell abundance and chlorophyll concentrations during Karenia brevis blooms

  2008cited by this paper
• Synthetic studies on maitotoxin. 1. Stereoselective synthesis of the C'D'E'F'-ring system having a side chain.

  2008cited by this paper
• Tetrodotoxin for moderate to severe cancer pain: a randomized, double blind, parallel design multicenter study.

  2008cited by this paper
• Synthetic studies on maitotoxin. 3. Stereoselective synthesis of the BCDE-ring system.

  2008cited by this paper
• S-adenosylmethionine synthetase genes from eleven marine dinoflagellates

  2007cited by this paper
• Recent advances in the synthesis of marine polycyclic ether natural products.

  2007cited by this paper
• An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain.

  2007cited by this paper
• The Gastropods Possessing TTX and/or PSP

  2007cited by this paper
• New Culture Approaches for Yessotoxin Production from the Dinoflagellate Protoceratium reticulatum

  2007influential reference
• Biomedicinals from the phytosymbionts of marine invertebrates: a molecular approach.

  2007cited by this paper
• Mechanical characterization of cellulosic thecal plates in dinoflagellates by nanoindentation.

  2007cited by this paper
• Species‐specific physiological response of dinoflagellates to quantified small‐scale turbulence 1

  2007influential reference
• Bioactive macrolides and polyketides from marine dinoflagellates of the genus Amphidinium.

  2007cited by this paper
• Heterotrophic dinoflagellates: a significant component of microzooplankton biomass and major grazers of diatoms in the sea

  2007cited by this paper
• Biotechnological significance of toxic marine dinoflagellates.

  2007influential reference
• The Sensitivity of the Dinoflagellate Crypthecodinium cohnii to Transient Hydrodynamic Forces and Cell‐Bubble Interactions

  2007influential reference
• Expression in mammalian cells using BacMam viruses

  2007cited by this paper
• Determination of shear stress thresholds in toxic dinoflagellates cultured in shaken flasks: Implications in bioprocess engineering

  2007influential reference
• Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula.

  2007cited by this paper
• Synthesis, Modeling, and Biological Evaluation of Analogues of the Semisynthetic Brevetoxin Antagonist β‐Naphthoyl‐Brevetoxin

  2007cited by this paper
• Study of the effect of temperature, irradiance and salinity on growth and yessotoxin production by the dinoflagellate Protoceratium reticulatum in culture by using a kinetic and factorial approach.

  2006cited by this paper
• Total synthesis of gambierol: the generation of the A-C and F-H subunits by using a C-glycoside centered strategy.

  2006cited by this paper
• The effect of environmental factors on the growth rate of Karenia brevis (Davis) G. Hansen and Moestrup

  2006cited by this paper
• Vertical migration of the toxic dinoflagellate Gymnodinium catenatum under different concentrations of nutrients and humic substances in culture

  2006cited by this paper
• Convergent Synthesis of the CDEF Ring Fragment of Yessotoxin via α‐Cyano Ethers.

  2006cited by this paper
• Shear rate in stirred tank and bubble column bioreactors

  2006cited by this paper
• Hydromechanical stress in shake flasks: Correlation for the maximum local energy dissipation rate

  2006cited by this paper
• Cloning of polyketide synthase genes from amphidinolide-producing dinoflagellate Amphidinium sp.

  2006influential reference
• Enhancement of growth and gymnodimine production by the marine dinoflagellate, Karenia selliformis

  2006cited by this paper
• The biosynthesis of polyketide metabolites by dinoflagellates.

  2006cited by this paper
• Temperature as a factor regulating growth and toxin content in the dinoflagellate Alexandrium catenella

  2006cited by this paper
• Marine natural products: synthetic aspects.

  2006cited by this paper
• Improvement in growth and toxin production of Alexandrium tamarense by two-step culture method

  2006cited by this paper
• Improved synthesis of the ABCDE fragment of brevetoxin A.

  2006cited by this paper
• Effect of small-scale shear on grazing and growth of the dinoflagellate Pfiesteria piscicida

  2006cited by this paper
• Biosynthesis of 13-desmethyl spirolide C by the dinoflagellate Alexandrium ostenfeldii.

  2006cited by this paper
• Involvement of calcium mobilization from caffeine-sensitive stores in mechanically induced cell cycle arrest in the dinoflagellate Crypthecodinium cohnii.

  2006cited by this paper
• Swiss mice CD1 fed on mussels contaminated by okadaic acid and yessotoxins: effects on thymus and spleen.

  2005cited by this paper

• Mass cultivation of the dinoflagellate Alexandrium pacificum for gonyautoxin-1,4 production

  2025cites this paper
• Effects of Amphidinium carterae Phytocompounds on Proliferation and the Epithelial–Mesenchymal Transition Process in T98G Glioblastoma Cells

  2025cites this paper
• Comparative Phycoremediation Potential of Micro-Green Algae and Dinoflagellates in Coastal and Inland Qatar

  2025cites this paper
• Amphidinium carterae growth in hydroponic wastewater. A sustainable approach to a microalgae-based process promoting a circular bioeconomy.

  2025cites this paper
• Mining marine dinoflagellate Amphidinium carterae for peridinin production by optimizing light conditions and mixotrophy strategy.

  2025cites this paper
• Exploring quorum sensing for inducing bioactives overproduction in the dinoflagellate microalga Amphidinium carterae

  2024cites this paper
• Antioxidant properties and bioactivity of three marine microalgae on human cancer cell lines

  2024cites this paper
• Investigating the Effects of Marine Dinoflagellate Biotoxins on the Environment and Humans

  2024cites this paper
• Preventing biofouling in microalgal photobioreactors.

  2024cites this paper
• Physiological and genetic responses of the benthic dinoflagellate Prorocentrum lima to polystyrene microplastics.

  2024cites this paper
• Exploring the potential of epigenetic chemicals to increase metabolite production in the dinoflagellate microalga Amphidinium carterae

  2024cites this paper
• Effects of hormones on the growth and metabolite production of Amphidinium carterae under carbon sufficient and carbon limited conditions

  2024cites this paper
• An Overview On The Marine Benthic Dinoflagellates Effects On Human and Environment

  2024cites this paper
• Antifungal activity of microalgae in phytopathogenic fungi: A systematic review

  2024cites this paper
• Light intensity changes and UVB radiation affect peridinin content and antioxidant activity in the Cassiopea andromeda holobiont

  2023cites this paper
• Acute Toxicity of the Dinoflagellate Amphidinium carterae on Early Life Stages of Zebrafish (Danio rerio)

  2023cites this paper
• Investigating the Effects of Marine Dinoflagellate Biotoxins on the Environment and Humans

  2023cites this paper
• Amphidinium spp. as a Source of Antimicrobial, Antifungal, and Anticancer Compounds

  2023cites this paper
• A study on the mechanism of the impact of phenthoate exposure on Prorocentrum lima.

  2023cites this paper
• Life-cycle assessment of a microalgae-based fungicide under a biorefinery approach.

  2023cites this paper
• The Potential of Allelochemicals from Microalgae for Biopesticides

  2023cites this paper
• Amphidinol C, a Major Polyketide from an Irish Strain of the Dinoflagellate Amphidinium Carterae

  2022cites this paper
• Effects of the Light Irradiance on the Growth and Lipid Content of Amphidinium carterae (Dinophyceae) for Biofuel Production

  2022cites this paper
• Rapid Screening of Polyol Polyketides from Marine Dinoflagellates

  2022cites this paper
• Effect of Nitrogen, Phosphorous, and Light Colimitation on Amphidinol Production and Growth in the Marine Dinoflagellate Microalga Amphidinium carterae

  2022cites this paper
• Treatment of secondary urban wastewater with a low ammonium-tolerant marine microalga using zeolite-based adsorption.

  2022cites this paper
• Alzheimer’s Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore

  2022cites this paper
• Environmental impact assessment of wastewater based biorefinery for the recovery of energy and valuable bio-based chemicals in a circular bioeconomy

  2021cites this paper
• Pathogens and predators impacting commercial production of microalgae and cyanobacteria.

  2021cites this paper
• Isolation and Structural Elucidation of New Amphidinol Analogues from Amphidinium carterae Cultivated in a Pilot-Scale Photobioreactor

  2021cites this paper
• Bioaccessibility and bioavailability of bioactive compounds delivered from microalgae

  2021cites this paper
• Aquaculture in the Alboran Sea

  2021cites this paper
• High Value Phycotoxins From the Dinoflagellate Prorocentrum

  2021cites this paper
• The Essentials of Marine Biotechnology

  2021cites this paper
• Calibration Curves of Culture Density Assessed by Spectrophotometer for Three Microalgae (Nephroselmis sp., Amphidinium carterae and Phormidium sp.)

  2020cites this paper
• Acclimation of the microalga Amphidinium carterae to different nitrogen sources: potential application in the treatment of marine aquaculture effluents

  2020cites this paper
• Bioremediation By Dinoflagellates

  2020cites this paper
• Production of extracts with anaesthetic activity from the culture of Heterosigma akashiwo in pilot-scale photobioreactors

  2020cites this paper
• Influence of culture medium recycling on the growth of a marine dinoflagellate microalga and bioactives production in a raceway photobioreactor

  2020cites this paper
• Extraction, properties and applications of bioactive compounds obtained from microalgae.

  2020cites this paper
• Improved extraction of bioactive compounds from biomass of the marine dinoflagellate microalga Amphidinium carterae.

  2020cites this paper
• Nontarget screening and toxicity evaluation of diol esters of okadaic acid and dinophysistoxins reveal intraspecies difference of Prorocentrum lima.

  2020cites this paper
• Toward Enhanced Fixation of CO2 in Aquatic Biomass: Focus on Microalgae

  2020cites this paper
• Semi-continuous cultivation of the mixotrophic dinoflagellate Gymnodinium smaydae, a new promising microalga for omega-3 production

  2020cites this paper
• Microalgae biotechnology: A brief introduction

  2020cites this paper
• Morphophysiological, structural, and metabolic aspects of microalgae

  2020cites this paper
• Enclosed “non-conventional” photobioreactors for microalga production: A review

  2020cites this paper
• Dinoflagellates Important Marine Producers of Natural Bio-Compounds with High Biotechnological and Pharmacological Potential

  2020cites this paper
• - i-Pharmaceutical Applications of Eukaryotic Microalgae

  2020cites this paper
• A mini review on challenges and opportunities in dinoflagellates cultivation

  2020influential citation
• Production of Amphidinols and Other Bioproducts of Interest by the Marine Microalga Amphidinium carterae Unraveled by Nuclear Magnetic Resonance Metabolomics Approach Coupled to Multivariate Data Analysis.

  2019cites this paper
• A new approach to finding optimal centrifugation conditions for shear-sensitive microalgae

  2019cites this paper
• Microalgae as a Potential Source of Proteins

  2019cites this paper
• HABs (Harmful Algal Blooms) Analysis, Their Cost, and Ecological Consequences

  2019cites this paper
• Mexican Aquatic Environments

  2019cites this paper
• Relative Configurational Assignment of 4-Hydroxyprorocentrolide and Prorocentrolide C Isolated from a Benthic Dinoflagellate ( Prorocentrum lima).

  2019cites this paper
• Pre-purification by membrane filtration of paralytic shellfish toxins from Alexandrium minutum dinoflagellate

  2019influential citation
• Assessment of multi-step processes for an integral use of the biomass of the marine microalga Amphidinium carterae.

  2019cites this paper
• References

  2019cites this paper
• Studies toward the Synthesis of Iriomoteolide-2a: Construction of the C(6)-C(28) Fragment.

  2018cites this paper
• A pilot-scale bioprocess to produce amphidinols from the marine microalga Amphidinium carterae : Isolation of a novel analogue

  2018cites this paper
• Effects of shear stress on microalgae - A review.

  2018cites this paper
• Pilot-scale outdoor photobioreactor culture of the marine dinoflagellate Karlodinium veneficum: Production of a karlotoxins-rich extract.

  2018cites this paper
• Aptamers and Aptasensors for Highly Specific Recognition and Sensitive Detection of Marine Biotoxins: Recent Advances and Perspectives

  2018cites this paper
• Long-term culture of the marine dinoflagellate microalga Amphidinium carterae in an indoor LED-lighted raceway photobioreactor: Production of carotenoids and fatty acids.

  2018cites this paper
• Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima.

  2017cites this paper
• Determination of Saxitoxin, Tetrodotoxin and Common Phycotoxins

  2017cites this paper
• Use of Antibiotics for Maintenance of Axenic Cultures of Amphidinium carterae for the Analysis of Translation

  2017cites this paper
• Marine Pharmacology in 2012–2013: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, and Antiviral Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action †

  2017cites this paper
• Modeling shear-sensitive dinoflagellate microalgae growth in bubble column photobioreactors.

  2017cites this paper
• Enzyme-linked, aptamer-based, competitive biolayer interferometry biosensor for palytoxin.

  2017cites this paper
• Spirulina - From growth to nutritional product: A review

  2017cites this paper
• Biotechnological and Pharmacological Applications of Biotoxins and Other Bioactive Molecules from Dinoflagellates

  2017influential citation
• Lipidomic Analysis of Marine Microalgae

  2016cites this paper
• Mixotrophy in the phototrophic dinoflagellate Takayama helix (family Kareniaceae): Predator of diverse toxic and harmful dinoflagellates.

  2016cites this paper
• New insights into shear-sensitivity in dinoflagellate microalgae.

  2016cites this paper
• The inhibitory effect of a non-yessotoxin-producing dinoflagellate, Lingulodinium polyedrum (Stein) Dodge, towards Vibrio vulnificus and Staphylococcus aureus.

  2016influential citation
• Artificial neural network modeling for predicting the growth of the microalga Karlodinium veneficum

  2016cites this paper
• The structure and mode of action of the dinoflagellate toxins

  2016cites this paper
• Methods for Upstream Extraction and Chemical Characterization of Secondary Metabolites from Algae Biomass

  2016cites this paper
• Long-term dinoflagellate culture performance in a commercial photobioreactor: Amphidinium carterae case.

  2016cites this paper
• Rapid method for the assessment of cell lysis in microalgae cultures

  2016cites this paper
• Antialgal and antilarval activities of bioactive compounds extracted from the marine dinoflagellate Amphidinium carterae

  2016cites this paper
• Harmful Algae and Their Commercial Implications

  2016cites this paper
• Biosynthetic Studies of 13-Desmethylspirolide C Produced by Alexandrium ostenfeldii (= A. peruvianum): Rationalization of the Biosynthetic Pathway Following Incorporation of (13)C-Labeled Methionine and Application of the Odd-Even Rule of Methylation.

  2016cites this paper
• Building a better mousetrap II: using Design of Experiments with unconfounded ions to compare the growth of different microalgae.

  2015cites this paper
• An optimal culture medium for growing Karlodinium veneficum: Progress towards a microalgal dinoflagellate-based bioprocess

  2015cites this paper
• Degradation of cyanotoxin cylindrospermopsin by TiO2-assisted ozonation in water

  2015cites this paper
• Euglenoid flagellates: a multifaceted biotechnology platform.

  2015cites this paper
• Notable decomposition products of senescing Lake Michigan Cladophora glomerata

  2014cites this paper
• Simultaneous Effect of Temperature and Irradiance on Growth and Okadaic Acid Production from the Marine Dinoflagellate Prorocentrum belizeanum

  2014cites this paper
• Marine natural products.

  2014cites this paper
• Evaluation of the grazer–prey interaction as a biotechnological strategy to increase toxin production by dinoflagellate cultures in photobioreactors

  2014cites this paper
• Immobilized Growth of the Peridinin-Producing Marine Dinoflagellate Symbiodinium in a Simple Biofilm Photobioreactor

  2014influential citation
• Gene Mining for Environmental Studies and Applications: Examples from Marine Organisms

  2014cites this paper
• How might we increase success in marine-based drug discovery?

  2014cites this paper
• Modelling of multi-nutrient interactions in growth of the dinoflagellate microalga Protoceratium reticulatum using artificial neural networks.

  2013cites this paper
• Algae fuels as an alternative to petroleum

  2013cites this paper
• Marine natural products.

  2012cites this paper