Multifunctional capacity and therapeutic potential of lactoferrin.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Life Science

• Publication date

  2018-02-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.lfs.2018.01.002PMID 29307524
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A systematic review of lactoferrin use in dermatology

  2017cited by this paper
• Antibacterial and cell penetrating effects of LFcin17-30, LFampin265-284, and LF chimera on enteroaggregative Escherichia coli.

  2017cited by this paper
• Apoptotic effects of bovine apo‐lactoferrin on HeLa tumor cells

  2017cited by this paper
• The Antifungal Activity of Lactoferrin and Its Derived Peptides: Mechanisms of Action and Synergy with Drugs against Fungal Pathogens

  2017cited by this paper
• Factors affecting lactoferrin concentration in human milk: how much do we know?

  2017cited by this paper
• Anticancer activities of bovine and human lactoferricin-derived peptides.

  2017cited by this paper
• Role of lactoferrin in neonatal care: a systematic review

  2017cited by this paper
• Overview of Lactoferrin as a Natural Immune Modulator.

  2016cited by this paper
• Bovine colostrum: an emerging nutraceutical

  2015cited by this paper
• Anticancer effects of lactoferrin: underlying mechanisms and future trends in cancer therapy.

  2014cited by this paper
• Lactoferrin for prevention of common viral infections.

  2014cited by this paper
• Potential lactoferrin activity against pathogenic viruses.

  2014cited by this paper
• [The importance of lactoferrin in bone regeneration].

  2014cited by this paper
• A study of effects of peptide fragments of bovine and human lactoferrins on activities of three key HIV-1 enzymes.

  2014cited by this paper
• Immunomodulatory effects of lactoferrin

  2014cited by this paper
• Suplementos dietéticos como tratamiento en el cáncer cervicouterino; revisión sistemática

  2013cited by this paper
• Effects of bovine lactoferrin to oral Candida albicans and Candida glabrata isolates recovered from the saliva in elderly people

  2013cited by this paper
• Structural diversity and mode of action on lipid membranes of three lactoferrin candidacidal peptides.

  2013cited by this paper
• Lactoferrin Administration into the Nostril Alleviates Murine Allergic Rhinitis and its Mechanisms

  2013cited by this paper
• [Dietary supplements as a treatment for cervical cancer: a systematic review].

  2013cited by this paper
• The Antimicrobial Peptide hLF1–11 Drives Monocyte-Dendritic Cell Differentiation toward Dendritic Cells That Promote Antifungal Responses and Enhance Th17 Polarization

  2012cited by this paper
• A novel extract from bovine colostrum whey supports anti-bacterial and anti-viral innate immune functions in vitro and in vivo: I. Enhanced immune activity in vitro translates to improved microbial clearance in animal infection models.

  2012cited by this paper
• Roles of lactoferrin on skin wound healing.

  2012cited by this paper
• Lactoferrin a multiple bioactive protein: An overview

  2011cited by this paper
• Modulation of HIV Binding to Epithelial Cells and HIV Transfer from Immature Dendritic Cells to CD4 T Lymphocytes by Human Lactoferrin and its Major Exposed LF-33 Peptide

  2011cited by this paper
• Lactoferrin as an effector molecule in the skeleton

  2010cited by this paper
• Human lactoferrin stimulates skin keratinocyte function and wound re‐epithelialization

  2010cited by this paper
• Prophylactic effect of bovine lactoferrin against acute toxoplasmosis in immunocompetent and immunosuppressed mice.

  2009cited by this paper
• Lactoferrin: structure, function and applications.

  2009cited by this paper
• Immunomodulatory effects of lactoferrin on antigen presenting cells.

  2009cited by this paper
• Inhibition of HBV infection by bovine lactoferrin and iron-, zinc-saturated lactoferrin

  2009cited by this paper
• Twenty-five years of research on bovine lactoferrin applications.

  2009cited by this paper
• Antimicrobial properties of lactoferrin.

  2009cited by this paper
• Lactoferrin as a natural immune modulator.

  2009cited by this paper
• Lactoferrin and Cancer Disease Prevention

  2008cited by this paper
• Lactoferrin structure and functions.

  2008cited by this paper
• Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells

  2008cited by this paper
• Lactoferrin

  2005cited by this paper
• Molecular structure, binding properties and dynamics of lactoferrin.

  2005cited by this paper
• The mode of oral bovine lactoferrin administration influences mucosal and systemic immune responses in mice.

  2004cited by this paper
• Reconstitution of the cellular immune response by lactoferrin in cyclophosphamide-treated mice is correlated with renewal of T cell compartment.

  2003cited by this paper
• Impact of lysozyme and lactoferrin on oral Candida isolates exposed to polyene antimycotics and fluconazole.

  2002cited by this paper
• International Journal of Molecular Sciences Lactoferrin: Balancing Ups and Downs of Inflammation Due to Microbial Infections

  year unknowncited by this paper

• Microenvironmental niches dictate divergent fibroblast fates in reversible versus progressive lung fibrosis

  2026cites this paper
• Estrogen and glucocorticoid promote the lactoferrin synthesis and secretion ability of bovine mammary epithelial cells through ER and GR signaling pathways.

  2025cites this paper
• Proteomics profiling of serum exosomes from azithromycin-sensitive and resistant Mycoplasma pneumoniae-infected patients reveals candidate biomarkers for diagnosis

  2025cites this paper
• In Silico Study of Molecular Docking Between Lactoferrin and Autophagy‐apoptosis Genes ATG3, ATG5, and ATG12 and In Vitro Study of Lactoferrin Effect on These Gene Expressions in Breast Cancer

  2025cites this paper
• Lactoferrin: Properties and Potential Uses in the Food Industry

  2025cites this paper
• Identification of Renal Transcripts Associated with Kidney Function and Prognosis in ANCA-Associated Vasculitis.

  2025cites this paper
• Repurposing pharmaceuticals for Alzheimer's treatment via adjusting the lactoferrin interacting proteins.

  2025cites this paper
• A Novel Nanocombination of Lactoferrin With Green Synthesized Zinc Oxide Nanoparticles for Alleviating Bleomycin‐Induced Oxidative Stress and Cardiotoxicity in Male Rats

  2025cites this paper
• Antifungal peptides from living organisms

  2024cites this paper
• Potensi laktoferin susu sapi sebagai antibiotik tunggal dan kombinasi dengan sefepim terhadap Pseudomonas aeruginosa secara in vitro

  2024cites this paper
• The impact of camel milk and its products on diabetes mellitus management: A review of bioactive components and therapeutic potential

  2024cites this paper
• Pretreatment-free aptasensing of lactoferrin in complex biological samples by portable electrophoretic mobility shift assay.

  2024cites this paper
• Detection and quantification of lactoferrin: Innovations, applications, and challenges.

  2024cites this paper
• The potential of lactoferrin as antiviral and immune-modulating agent in viral infectious diseases

  2024cites this paper
• Three in One with Dual-Functional Hydrogel of Lactoferrin/NZ2114/LMSH Promoting Staphylococcus aureus-Infected Wound Healing

  2024cites this paper
• Assessment of Supplementation with Different Biomolecules in the Prevention and Treatment of COVID-19

  2024cites this paper
• Bovine lactoferrin inhibits Plasmodium berghei growth by binding to heme

  2024cites this paper
• In Silico Determination of Physicochemical Properties of Lactoferrin Peptides Isolated from Equine Milk

  2024cites this paper
• A review of the biological activities of lactoferrin: mechanisms and potential applications.

  2024cites this paper
• Hierarchical Micro- and Mesoporous Zeolitic Imidazolate Framework-8-Based Enzyme Hybrid for Combination Antimicrobial by Lysozyme and Lactoferrin.

  2024cites this paper
• Application of lactoferrin in food packaging: A comprehensive review on opportunities, advances, and horizons.

  2024cites this paper
• Managing children with frequent respiratory infections and associated wheezing: a preliminary randomized study with a new multicomponent nasal spray.

  2024cites this paper
• Integration of metalloproteome and immunoproteome reveals a tight link of iron-related proteins with COVID-19 pathogenesis and immunity.

  2024cites this paper
• Bovine Lactoferrin and Current Antifungal Therapy Against Candida Albicans: A Systematic Review and Meta-Analysis

  2024cites this paper
• Synergistic Effect of Retinoic Acid and Lactoferrin in the Maintenance of Gut Homeostasis

  2024cites this paper
• Therapeutic uses and applications of bovine lactoferrin in aquatic animal medicine: an overview

  2023cites this paper
• A Prospective Randomized Interventional Study to Establish the Role of Bovine Lactoferrin in Helicobacter Pylori Infection

  2023cites this paper
• Lactoferrin: A glycoprotein that plays an active role in human health

  2023cites this paper
• Silver Lactoferrin as Antimicrobials: Mechanisms of Action and Resistance Assessed by Bacterial Molecular Profiles

  2023cites this paper
• Antimicrobial Effects of Lactoferrin against Helicobacter pylori Infection

  2023cites this paper
• Camel Milk-Derived Bioactive Peptides and Diabetes: Molecular View and Perspectives.

  2023cites this paper
• Encapsulation of Iron-Saturated Lactoferrin for Proteolysis Protection with Preserving Iron Coordination and Sustained Release

  2023cites this paper
• Darier’s disease exhibits a unique cutaneous microbial dysbiosis associated with inflammation and body malodour

  2023cites this paper
• The effect of bovine milk lactoferrin-loaded exosomes (exoLF) on human MDA-MB-231 breast cancer cell line

  2023cites this paper
• Lactoferrin: Antimicrobial impacts, genomic guardian, therapeutic uses and clinical significance for humans and animals.

  2023cites this paper
• Label-free quantitative proteomic analysis of milk fat globule membrane proteins in porcine colostrum and mature milk.

  2023cites this paper
• Nutraceutical and Health-Promoting Potential of Lactoferrin, an Iron-Binding Protein in Human and Animal: Current Knowledge

  2023cites this paper
• Improving Effects of Laccase-Mediated Pectin–Ferulic Acid Conjugate and Transglutaminase on Active Peptide Production in Bovine Lactoferrin Digests

  2023cites this paper
• Enhanced Bioactive Potential of Functionalized Injectable Platelet-Rich Plasma

  2023cites this paper
• Efficacy of Inferrin^TM and Lactoferrin on Symptoms of Irritable Bowel Syndrome in Otherwise Healthy Adults: A Randomised, Double-Blind, Placebo-Controlled Study

  2023cites this paper
• Antimicrobial peptides derived from microalgae for combating antibiotic resistance: Current status and prospects

  2023cites this paper
• Iron transport mechanism of lactoferrin and its application in food processing

  2023cites this paper
• Comprehensive Transcriptome Analysis of Patients With Keratoconus Highlights the Regulation of Immune Responses and Inflammatory Processes

  2022cites this paper
• Lactoferrin improves hepatic pyroptosis in mice exposured irradiation

  2022cites this paper
• Antioxidant Activity of Milk and Dairy Products

  2022cites this paper
• Reduction of lactoferrin aggravates neuronal ferroptosis after intracerebral hemorrhagic stroke in hyperglycemic mice

  2022cites this paper
• Camel Milk Targeting Insulin Receptor—Toward Understanding the Antidiabetic Effects of Camel Milk

  2022cites this paper
• Evaluating the in vitro efficacy of bovine lactoferrin products against SARS-CoV-2 variants of concern

  2022cites this paper
• Effect of fluocinolone acetonide (0.1%) treatment in oral lichen planus patients on salivary lactoferrin levels and Candida colonization: a prospective study

  2022cites this paper
• Probiotic Mixture Containing Lactobacillus helveticus, Bifidobacterium longum and Lactiplantibacillus plantarum Affects Brain Responses Toward an Emotional Task in Healthy Subjects: A Randomized Clinical Trial

  2022cites this paper
• Recombinant Human Lactoferrin Augments Epirubicin Chemotherapy in Solid Ehrlich Carcinoma Bearing Mice.

  2022cites this paper
• Lactotransferrin promotes intervertebral disc degeneration by regulating Fas and inhibiting human nucleus pulposus cell apoptosis

  2022cites this paper
• Lactoferrin modulates the biofilm formation and bap gene expression of methicillin-resistant Staphylococcus epidermidis.

  2022cites this paper
• A comprehensive review on lactoferrin: a natural multifunctional glycoprotein.

  2022cites this paper
• Bovine lactoferrin inhibits SARS‐CoV‐2 and SARS‐CoV‐1 by targeting the RdRp complex and alleviates viral infection in the hamster model

  2022cites this paper
• Effects of dietary supplementation of bovine lactoferrin on growth performance, immune function and intestinal health in weaning piglets

  2022influential citation
• Recent advancements in the genetic engineering of microalgae

  2021cites this paper
• Camel and bovine milk lactoferrins activate insulin receptor and its related AKT and ERK1/2 pathways.

  2021cites this paper
• Lactoferrin Alleviated AFM1-Induced Apoptosis in Intestinal NCM 460 Cells through the Autophagy Pathway

  2021cites this paper
• Mitochondrial Oxidative Stress—A Causative Factor and Therapeutic Target in Many Diseases

  2021cites this paper
• Camel whey protein (CWP) ameliorates liver injury in type 2 diabetes mellitus rats and insulin resistance (IR) in HepG2 cells via activation of the PI3K/Akt signaling pathway.

  2021cites this paper
• The functions of lactoferine in the oral cavity

  2021influential citation
• Multifunctional Titanium Surfaces for Orthopedic Implants: Antimicrobial Activity and Enhanced Osseointegration.

  2021cites this paper
• Effects of Dietary Supplementation of Bovine Lactoferricin on Rumen Microbiota, Lactation, and Health in Dairy Goats

  2021cites this paper
• Inhibition of breast cancer xenografts in a mouse model and the induction of apoptosis in multiple breast cancer cell lines by lactoferricin B peptide

  2021cites this paper
• Non-pharmacological remedies for the common cold.

  2021cites this paper
• Lactoferrin-ginsenoside Rg3 complex ingredients: Study of interaction mechanism and preparation of oil-in-water emulsion.

  2021cites this paper
• Protective Action of L. salivarius SGL03 and Lactoferrin against COVID-19 Infections in Human Nasopharynx

  2021cites this paper
• Current Research in Pulsed Laser Deposition

  2021cites this paper
• Can nutraceuticals assist treatment and improve covid-19 symptoms?

  2021cites this paper
• Lactoferrin perturbs lipid rafts and requires integrity of Pma1p-lipid rafts association to exert its antifungal activity against Saccharomyces cerevisiae.

  2021cites this paper
• Lactoferrin for the treatment of COVID-19 (Review)

  2020cites this paper
• The Protective Effect of Lactoferrin on Adenosine Deaminase, Nitric Oxide and Liver Enzymes in Lipopolysaccharide-Induced Experimental Endotoxemia Model in Rats

  2020cites this paper
• Enhancing the antibacterial activities of sow milk via site-specific knock-in of a lactoferrin gene in pigs using CRISPR/Cas9 technology

  2020cites this paper
• Recombinant human lactoferrin carrying humanized glycosylation exhibits antileukemia selective cytotoxicity, microfilament disruption, cell cycle arrest, and apoptosis activities

  2020cites this paper
• EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES: Albumin fusion at the N-terminus or C-terminus of human lactoferrin leads to improved pharmacokinetics and anti-proliferative effects on cancer cell lines.

  2020cites this paper
• Lactoferrin Induces Tolerogenic Bone Marrow-Derived Dendritic Cells

  2020cites this paper
• Selective Identification of Alpha Galactosyl Epitopes in N-Glycoproteins using Characteristic Fragment Ions from Higher-energy Collisional Dissociation.

  2020cites this paper
• Lactoferrin Functionalized Biomaterials: Tools for Prevention of Implant-Associated Infections

  2020cites this paper
• Antiviral Action of Native and Methylated Lactoferrin and β-Lactoglobulin against Potato Virus Y (PVY) Infected into Potato Plants Grown in an Open Field

  2020cites this paper
• Antitumor effects of targeting myeloid-derived suppressive cells

  2020cites this paper
• Lactoferrin Association with Maternal Nutritional Status and Lactation Stages

  2020cites this paper
• Lactoferrin improves cognitive function and attenuates brain senescence in aged mice

  2020cites this paper
• Fluorescence spectroscopy and molecular modeling of anthocyanins binding to bovine lactoferrin peptides.

  2020cites this paper
• Macrophage in vitro Response on Hybrid Coatings Obtained by Matrix Assisted Pulsed Laser Evaporation

  2019cites this paper
• Bovine lactoferrin quantification in dairy products by a simple immunoaffinity magnetic purification method coupled with high-performance liquid chromatography with fluorescence detection.

  2019cites this paper
• Pepsin-catalyzed plastein reaction with tryptophan increases the in vitro activity of lactoferrin hydrolysates with BGC-823 cells

  2019cites this paper
• Nanoparticles of lactoferrin for encapsulation of food ingredients

  2019cites this paper
• An overview of biopolymer nanostructures for encapsulation of food ingredients

  2019cites this paper
• Cellular Uptake and Release of Intact Lactoferrin and Its Derivatives in an Intestinal Enterocyte Model of Caco-2 Cells.

  2019cites this paper
• Effects of Candida albicans infection on defense effector secretion by human oral mucosal epithelial cells.

  2019cites this paper
• Strategies for oral delivery of metal-saturated lactoferrin.

  2019cites this paper
• Lactoferrin as a nutraceutical protein from milk, an overview

  2019cites this paper
• Changes in C-reactive protein, neopterin and lactoferrin differ after conservative and surgical weight loss in individuals with morbid obesity

  2019cites this paper
• Human Mesenchymal Stem Cell Response to Lactoferrin-based Composite Coatings

  2019cites this paper
• Lactoferrin deficiency induces a pro-metastatic tumor microenvironment through recruiting myeloid-derived suppressor cells in mice

  2019cites this paper
• Expression and characterization of recombinant human lactoferrin in edible alga Chlamydomonas reinhardtii

  2019cites this paper
• Role of Lactoferrin in Neonates and Infants: An Update

  2018cites this paper
• Lactoferrin as Nutraceutical Protein from Milk

  2018cites this paper
• CARMUSTINE LOADED LACTOFERRIN NANOPARTICLES DEMONSTRATES AN ENHANCED ANTIPROLIFERATIVE ACTIVITY AGAINST GLIOBLASTOMA IN VITRO

  2018cites this paper