TRAF3IP2 mediates atherosclerotic plaque development and vulnerability in ApoE(-/-) mice.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Atherosclerosis

• Publication date

  2016-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.atherosclerosis.2016.05.029PMID 27237075PMCID PMC5035578
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vascular Smooth Muscle Cells in Atherosclerosis.

  2016cited by this paper
• The paradoxical role of IL-17 in atherosclerosis.

  2015cited by this paper
• Aldosterone-induced cardiomyocyte growth, and fibroblast migration and proliferation are mediated by TRAF3IP2.

  2015cited by this paper
• Global Overview of the Epidemiology of Atherosclerotic Cardiovascular Disease.

  2015cited by this paper
• Mechanisms of plaque formation and rupture.

  2014cited by this paper
• OxLDL induces endothelial dysfunction and death via TRAF3IP2: inhibition by HDL3 and AMPK activators.

  2014cited by this paper
• Network Analysis of Inflammatory Genes and Their Transcriptional Regulators in Coronary Artery Disease

  2014cited by this paper
• IL-17A Influences Essential Functions of the Monocyte/Macrophage Lineage and Is Involved in Advanced Murine and Human Atherosclerosis

  2014cited by this paper
• Aldosterone Increases Early Atherosclerosis and Promotes Plaque Inflammation Through a Placental Growth Factor‐Dependent Mechanism

  2013cited by this paper
• CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.

  2013cited by this paper
• Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide‐dependent TRAF3IP2/JNK signaling

  2013cited by this paper
• TRAF3IP2 mediates interleukin-18-induced cardiac fibroblast migration and differentiation.

  2013cited by this paper
• Role of protein kinase C δ in ER stress and apoptosis induced by oxidized LDL in human vascular smooth muscle cells

  2013cited by this paper
• Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.

  2013cited by this paper
• CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy.

  2012cited by this paper
• Conditional Targeting of Tumor Necrosis Factor Receptor–Associated Factor 6 Reveals Opposing Functions of Toll-Like Receptor Signaling in Endothelial and Myeloid Cells in a Mouse Model of Atherosclerosis

  2012cited by this paper
• IL‐17 mediates estrogen‐deficient osteoporosis in an Act1‐dependent manner

  2012cited by this paper
• Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

  2011cited by this paper
• Macrophages in the pathogenesis of atherosclerosis.

  2011cited by this paper
• Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention study

  2011cited by this paper
• Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium.

  2011cited by this paper
• Expression of IL-17A in human atherosclerotic lesions is associated with increased inflammation and plaque vulnerability

  2010cited by this paper
• TNFα-induced macrophage death via caspase-dependent and independent pathways

  2009cited by this paper
• The Adaptor Protein CIKS/Act1 Is Essential for IL-25-Mediated Allergic Airway Inflammation1

  2009cited by this paper
• Act1, a U-box E3 Ubiquitin Ligase for IL-17 Signaling

  2009cited by this paper
• Increased ADAM17 mRNA Expression and Activity Is Associated With Atherosclerosis Resistance in LDL-Receptor Deficient Mice

  2008cited by this paper
• The Long-Term Effect of Angiotensin II Type 1a Receptor Deficiency on Hypercholesterolemia-Induced Atherosclerosis

  2008cited by this paper
• Endothelial cell-specific NF-kappaB inhibition protects mice from atherosclerosis.

  2008cited by this paper
• TRAF-1, -2, -3, -5, and -6 Are Induced in Atherosclerotic Plaques and Differentially Mediate Proinflammatory Functions of CD40L in Endothelial Cells

  2007cited by this paper
• TRAF-1, -2, -3, -5, and -6 Are Induced in Atherosclerotic Plaques and Differentially Mediate Proinflammatory Functions of CD40L in Endothelial Cells

  2007cited by this paper
• A CD36‐dependent signaling cascade is necessary for macrophage foam cell formation

  2006cited by this paper
• Act1 Adaptor Protein Is an Immediate and Essential Signaling Component of Interleukin-17 Receptor*

  2006cited by this paper
• Insulin‐like growth factor‐1 and TNF‐α regulate autophagy through c‐jun N‐terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells

  2006cited by this paper
• IL-18 Accelerates Atherosclerosis Accompanied by Elevation of IFN-&ggr; and CXCL16 Expression Independently of T Cells

  2005cited by this paper
• Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis.

  2004cited by this paper
• Activation of Discoidin Domain Receptor 1 Facilitates the Maturation of Human Monocyte-Derived Dendritic Cells Through the TNF Receptor Associated Factor 6/TGF-β-Activated Protein Kinase 1 Binding Protein 1β/p38α Mitogen-Activated Protein Kinase Signaling Cascade

  2003cited by this paper
• Tumor Necrosis Factor-&agr; Promotes Macrophage-Induced Vascular Smooth Muscle Cell Apoptosis by Direct and Autocrine Mechanisms

  2003cited by this paper
• Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout mice.

  2003cited by this paper
• Expression of Interleukin-18 in Human Atherosclerotic Plaques and Relation to Plaque Instability

  2001cited by this paper
• Act1, an NF-kappa B-activating protein.

  2000cited by this paper
• CIKS, a connection to Ikappa B kinase and stress-activated protein kinase.

  2000cited by this paper
• Expression of angiotensin II and interleukin 6 in human coronary atherosclerotic plaques: potential implications for inflammation and plaque instability.

  2000cited by this paper
• Increased expression and activation of stress-activated protein kinases/c-Jun NH(2)-terminal protein kinases in atherosclerotic lesions coincide with p53.

  2000cited by this paper
• GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and bcl-2 in a murine myeloid cell line M1.

  2000cited by this paper
• Act1, an NF-κB-activating protein

  2000cited by this paper
• Nuclear factor-κB regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells

  1999cited by this paper
• Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells.

  1999cited by this paper
• The Nuclear Factor κ-B Signaling Pathway Participates in Dysregulation of Vascular Smooth Muscle Cells in Vitroand in Human Atherosclerosis*

  1997cited by this paper
• Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

  1996cited by this paper

• The Roles of the Membrane-Anchored Glycoprotein RECK in Animal Development, Tumor Suppression, and Beyond

  2026cites this paper
• TRAF3IP2 as a novel inflammatory biomarker for coronary artery disease: development and validation of a multimodal prediction model

  2025cites this paper
• The role of IL-17 and Th17 cells in keloid pathogenesis

  2024cites this paper
• Klotho inversely relates with carotid intima- media thickness in atherosclerotic patients with normal renal function (eGFR ≥60 mL/min/1.73m2): a proof-of-concept study

  2023cites this paper
• The Role of ADAM17 in Inflammation-Related Atherosclerosis

  2022cites this paper
• Effects of Empagliflozin on Intermittent Hypoxia-Induced TRAF3IP2-Dependent Human Aortic Smooth Muscle Cell Proliferation

  2022cites this paper
• New insights into mechanisms of endothelial insulin resistance in type 2 diabetes.

  2022cites this paper
• Investigating the relationship between the severity of coronary artery disease and expression level of TRAF3IP2

  2021cites this paper
• Downregulation of Macrophage-Specific Act-1 Intensifies Periodontitis and Alveolar Bone Loss Possibly via TNF/NF-κB Signaling

  2021cites this paper
• MiR-32-3p Regulates Myocardial Injury Induced by Microembolism and Microvascular Obstruction by Targeting RNF13 to Regulate the Stability of Atherosclerotic Plaques

  2021cites this paper
• Targeting TRAF3IP2 alleviates high glucose‐induced cardiomyocyte inflammation and apoptosis

  2021cites this paper
• TRAF3IP2 (TRAF3 Interacting Protein 2) Mediates Obesity-Associated Vascular Insulin Resistance and Dysfunction in Male Mice

  2020cites this paper
• The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretion.

  2020cites this paper
• TIPE1 accelerates atherogenesis by inducing endothelial dysfunction in response to oxidative stress.

  2019cites this paper
• Knockdown of TRAF3IP2 suppresses the expression of VEGFA and the proliferation of keratinocytes and vascular endothelial cells

  2019cites this paper
• Effects of Cervical Rotatory Manipulation (CRM) on Carotid Atherosclerosis Plaque in Vulnerability: A Histological and Immunohistochemical Study Using Animal Model

  2019cites this paper
• Giresun İlinde FV, FXIII, ACE, ApoE Gen Varyantlarının Prevelansı ve Koroner Arter Hastalığı Profiline Etkilerinin Araştırılması

  2019cites this paper
• Crocin alleviates coronary atherosclerosis via inhibiting lipid synthesis and inducing M2 macrophage polarization

  2018cites this paper
• Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction *

  2016cites this paper
• ScholarWorks @ UTRGV ScholarWorks @ UTRGV

  year unknowncites this paper