Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-element oligonucleotide array.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Physiological Genomics

• Publication date

  2003-03-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/PHYSIOLGENOMICS.00157.2002PMID 12644634
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CCL27–CCR10 interactions regulate T cell–mediated skin inflammation

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• Differing Activities of Homeostatic Chemokines CCL19, CCL21, and CXCL12 in Lymphocyte and Dendritic Cell Recruitment and Lymphoid Neogenesis1

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• Searching for the major histocompatibility complex psoriasis susceptibility gene.

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• Immunotherapy for psoriasis: from serendipity to selectivity.

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• The immunologic basis for the treatment of psoriasis with new biologic agents.

  2002influential reference
• Sequential involvement of CCR2 and CCR6 ligands for immature dendritic cell recruitment: possible role at inflamed epithelial surfaces

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• Psoriasis as a model for T-cell-mediated disease: immunobiologic and clinical effects of treatment with multiple doses of efalizumab, an anti-CD11a antibody.

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• Analysis of gene expression using high-density and IFN-gamma-specific low-density cDNA arrays.

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  2001cited by this paper
• Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies.

  2001influential reference
• Role of integrin alphaE(CD103)beta7 for tissue-specific epidermal localization of CD8+ T lymphocytes.

  2001cited by this paper
• Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgaris.

  2001cited by this paper
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• Molecular classification of psoriasis disease-associated genes through pharmacogenomic expression profiling

  2001cited by this paper
• Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection.

  2001cited by this paper
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  2001influential reference
• Differential expression of CXCR3 targeting chemokines CXCL10, CXCL9, and CXCL11 in different types of skin inflammation

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  2000influential reference
• CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry.

  2000cited by this paper
• Macrophage Inflammatory Protein 3α Is Expressed at Inflamed Epithelial Surfaces and Is the Most Potent Chemokine Known in Attracting Langerhans Cell Precursors

  2000cited by this paper
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  2000influential reference
• Impact of different low-density lipoprotein (LDL) receptor mutations on the ability of LDL to support lymphocyte proliferation.

  1999cited by this paper
• Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.

  1999cited by this paper
• Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIalpha gene promoter.

  1999influential reference
• Cluster analysis and display of genome-wide expression patterns.

  1998cited by this paper
• IL-1 and IL-1 receptor antagonist regulation during keratinocyte cell cycle and differentiation in normal and psoriatic epidermis

  1998cited by this paper
• The C–X–C chemokine Mig is highly expressed in the papillae of psoriatic lesions

  1998cited by this paper
• The genetics of psoriasis: a complex disorder of the skin and immune system.

  1998cited by this paper
• Activation of the Human DNA Polymerase β Promoter by a DNA-alkylating Agent through Induced Phosphorylation of cAMP Response Element-binding Protein-1*

  1996cited by this paper
• Differential expression of GRO-alpha and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vivo.

  1996cited by this paper
• Differential Expression of GRO-α and IL-8 mRNA Psoriasis: A Model for Neutrophil Migration and Accumulation In Vivo

  1996cited by this paper
• Major Histocompatibility Complex Class II-associated Invariant Chain Gene Expression Is Up-regulated by Cooperative Interactions of Sp1 and NF-Y (*)

  1995cited by this paper
• Pathogenesis of psoriasis.

  1995cited by this paper
• Immunopathogenesis and immunotherapy of psoriasis.

  1995cited by this paper
• Cell cycle regulation of the cyclin A, cdc25C and cdc2 genes is based on a common mechanism of transcriptional repression.

  1995cited by this paper
• Localization of the inducible enhancer in the mouse interleukin-5 gene that is responsive to T-cell receptor stimulation.

  1995cited by this paper
• Pathogenesis of Psoriasis: Current Concepts

  1995cited by this paper
• MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions.

  1993cited by this paper
• Psoriasis in practice.

  1991cited by this paper
• Structure and Function of Leukocyte Integrins

  1990cited by this paper
• A monoclonal antibody (HML‐1) defining a novel membrane molecule present on human intestinal lymphocytes

  1987cited by this paper
• Psoriasis: familial predisposition and environmental factors.

  1985cited by this paper
• Pathogenesis of psoriasis.

  1983cited by this paper
• Pathophysiology of psoriasis.

  1977cited by this paper

• Connecting Genes to Physiology: The First 25 Years of Physiological Genomics.

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• Secukinumab and Dead Sea Climatotherapy Impact Resolved Psoriasis Skin Differently Potentially Affecting Disease Memory

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• Cytokines in psoriasis: From pathogenesis to targeted therapy.

  2024cites this paper
• Psoriasis Comorbidities and Shared Disease Mechanisms – An Investigation using Systems Biology approaches

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• Promising prospects of lipid-based topical nanocarriers for the treatment of psoriasis

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• Role of the CXCR6/CXCL16 axis in autoimmune diseases.

  2023cites this paper
• Assessment of Treatment-Relevant Immune Biomarkers in Psoriasis and Atopic Dermatitis: Toward Personalized Medicine in Dermatology.

  2023cites this paper
• Deucravacitinib, a selective tyrosine kinase 2 inhibitor, for the treatment of moderate-to-severe plaque psoriasis

  2023cites this paper
• Computational protein subgraph analysis provides insights into effective therapeutic management of psoriasis and its comorbidities

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  2022cites this paper
• A new ex vivo skin model for mechanistic understanding of putative anti-inflammatory topical therapeutics.

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• Promising Strategies in Plant-Derived Treatments of Psoriasis-Update of In Vitro, In Vivo, and Clinical Trials Studies

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• Treatments for psoriasis: A journey from classical to advanced therapies. How far have we reached?

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• Transcriptional Basis of Psoriasis from Large Scale Gene Expression Studies: The Importance of Moving towards a Precision Medicine Approach

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• Psoriasis is a disease of the entire skin: non-lesional skin displays a prepsoriasis phenotype

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  2021cites this paper
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• Using evasins to target the chemokine network in inflammation.

  2020cites this paper
• Effect of white mange mixture in a murine model of psoriasis

  2019cites this paper
• Effect of white mange mixture in a murine model of psoriasis.

  2019cites this paper
• Bioinformatic applications in psoriasis: genetics, transcriptomics, and microbiomics.

  2019cites this paper
• Quo vadis, biological treatment for psoriasis and psoriatic arthritis?

  2018cites this paper
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  2015cites this paper
• Tofacitinib for the treatment of moderate-to-severe psoriasis

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• Analyse par profilage génique du phénotype psoriasique des substituts cutanés produits par la méthode d'auto-assemblage

  2015cites this paper
• Psoriasis – An Overview

  2015cites this paper
• MicroRNAs in normal and psoriatic skin.

  2014cites this paper
• Autoinflammatory Diseases Affecting Predominantly the Skin

  2014cites this paper
• Proteomics of Skin Proteins in Psoriasis: From Discovery and Verification in a Mouse Model to Confirmation in Humans*

  2014cites this paper
• IL-36: An Epithelial Cytokine Important in Psoriasis

  2014cites this paper
• This information is current as Receptor Antagonist Signaling through the IL-36 Molecular Determinants of Agonist and

  2014cites this paper
• An increased proportion of circulating Th22 and Tc22 cells in psoriasis.

  2014cites this paper
• Epigenetics in the pathogenesis and pathophysiology of psoriasis vulgaris.

  2014cites this paper
• Abnormal Levels of Expression of Plasma MicroRNA-33 in Patients With Psoriasis

  2014cites this paper
• The genetics of human skin disease.

  2014cites this paper
• What have we learned about non-involved psoriatic skin from large-scale gene expression studies?

  2014cites this paper
• Transcriptome analysis of psoriasis in a large case-control sample: RNA-seq provides insights into disease mechanisms

  2014influential citation
• Alpha-1 antitrypsin, retinol binding protein and keratin 10 alterations in patients with psoriasis vulgaris, a proteomic approach

  2014cites this paper
• IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

  2014cites this paper
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  2014cites this paper
• Abnormal levels of expression of plasma microRNA-33 in patients with psoriasis.

  2014cites this paper
• RNA-seq Permits a Closer Look at Normal Skin and Psoriasis Gene Networks

  2014cites this paper
• Study on Certain Biomarkers of Inflammation in Psoriasis Through “OMICS” Platforms

  2014influential citation
• Chemokines and cytokines network in the pathogenesis of the inflammatory skin diseases: atopic dermatitis, psoriasis and skin mastocytosis

  2014cites this paper
• [Psoriasis: physiopathology and immunogenetics].

  2014cites this paper
• An Important Role of the SDF-1/CXCR4 Axis in Chronic Skin Inflammation

  2014cites this paper
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  2013cites this paper
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