Technical Advance: Function and efficacy of an α4‐integrin antagonist using bioluminescence imaging to detect leukocyte trafficking in murine experimental colitis

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Leukocyte Biology

• Publication date

  2010-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1189/jlb.0909627PMID 20739616
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis.

  2009cited by this paper
• Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS‐Induced Colitis

  2009cited by this paper
• A protective function for interleukin 17A in T cell–mediated intestinal inflammation

  2009cited by this paper
• Increased expression of VEGF and CD146 in patients with inflammatory bowel disease.

  2008cited by this paper
• Roles of nitric oxide (NO) and NO synthases in healing of dextran sulfate sodium-induced rat colitis.

  2008cited by this paper
• Leukocyte adhesion molecules in animal models of inflammatory bowel disease

  2008influential reference
• Validation of murine dextran sulfate sodium-induced colitis using four therapeutic agents for human inflammatory bowel disease.

  2008cited by this paper
• Treatment of Ulcerative Colitis With a Humanized Antibody to the α4β7 Integrin

  2007cited by this paper
• Molecular Imaging of Bone Marrow Mononuclear Cell Homing and Engraftment in Ischemic Myocardium

  2007cited by this paper
• Inhibition of eosinophilia in vivo by a small molecule inhibitor of very late antigen (VLA)-4.

  2007cited by this paper
• Cutting Edge: Regulatory T Cells Induce CD4+CD25−Foxp3− T Cells or Are Self-Induced to Become Th17 Cells in the Absence of Exogenous TGF-β

  2007cited by this paper
• Healing Impairment Effect of Cyclooxygenase Inhibitors on Dextran Sulfate Sodium-Induced Colitis in Rats

  2007cited by this paper
• A small molecule, orally active, α4β1/α4β7 dual antagonist reduces leukocyte infiltration and airway hyper‐responsiveness in an experimental model of allergic asthma in Brown Norway rats

  2006cited by this paper
• Interleukin-17 is a negative regulator of established allergic asthma

  2006cited by this paper
• Magnetic resonance imaging of experimental mouse colitis and association with inflammatory activity

  2006cited by this paper
• Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.

  2006cited by this paper
• The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells.

  2006cited by this paper
• Angiogenesis blockade as a new therapeutic approach to experimental colitis

  2006cited by this paper
• A small molecule, orally active, alpha4beta1/alpha4beta7 dual antagonist reduces leukocyte infiltration and airway hyper-responsiveness in an experimental model of allergic asthma in Brown Norway rats.

  2006cited by this paper
• Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.

  2006cited by this paper
• Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation.

  2005cited by this paper
• Treatment of ulcerative colitis with a humanized antibody to the alpha4beta7 integrin.

  2005cited by this paper
• Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation.

  2005cited by this paper
• Anti-adhesion therapies.

  2005cited by this paper
• Natalizumab induction and maintenance therapy for Crohn's disease.

  2005cited by this paper
• Bioluminescence imaging.

  2005cited by this paper
• Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice.

  2004cited by this paper
• Revealing lymphoma growth and the efficacy of immune cell therapies using in vivo bioluminescence imaging.

  2003cited by this paper
• A controlled trial of natalizumab for relapsing multiple sclerosis.

  2003cited by this paper
• Evaluation of effector cell fate and function by in vivo bioluminescence imaging.

  2003cited by this paper
• Natalizumab for active Crohn's disease.

  2003influential reference
• IL-17 Selectively Down-Regulates TNF-α-Induced RANTES Gene Expression in Human Colonic Subepithelial Myofibroblasts1

  2002cited by this paper
• [Expression of fusion proteins in beta(2)GP I gene-transfected HEp-2 cells and its clinical application].

  2002cited by this paper
• Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives: discovery of TR-14035, a dual alpha(4)beta(7)/alpha(4)beta(1) integrin antagonist.

  2002cited by this paper
• Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method.

  2001cited by this paper
• Loss of transforming growth factor β signalling in the intestine contributes to tissue injury in inflammatory bowel disease

  2001cited by this paper
• Role of inducible nitric oxide synthase in the regulation of leucocyte recruitment.

  2001cited by this paper
• In vivo imaging of light-emitting probes.

  2001cited by this paper
• Adoptive Immunotherapy of Experimental Autoimmune Encephalomyelitis Via T Cell Delivery of the IL-12 p40 Subunit1

  2001cited by this paper
• Supplemental dietary arginine enhances wound healing in normal but not inducible nitric oxide synthase knockout mice.

  2000cited by this paper
• Visualizing the kinetics of tumor-cell clearance in living animals.

  1999cited by this paper
• VCAM-1 and ICAM-1 mediate leukocyte-endothelial cell adhesion in rat experimental colitis.

  1999cited by this paper
• Expression of lymphocyte-endothelial receptor-ligand pairs, α4β7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease

  1999cited by this paper
• Increased serum levels of vascular endothelial growth factor in patients with inflammatory bowel disease.

  1998cited by this paper
• Bioluminescent indicators in living mammals

  1998cited by this paper
• [The change of serum alpha 1-antitrypsin level in patients with spontaneous pneumothorax].

  1995cited by this paper
• Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.

  1994cited by this paper
• Attenuation of colitis in the cotton-top tamarin by anti-alpha 4 integrin monoclonal antibody.

  1993cited by this paper
• Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers.

  1993cited by this paper
• Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2 2 DD C T Method

  year unknowncited by this paper
• The Orphan Nuclear Receptor ROR g t Directs the Differentiation Program of Proinflammatory IL-17 + T Helper Cells

  year unknowncited by this paper

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  2021cites this paper
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  2021cites this paper
• Whey protein effects on energy balance link the intestinal mechanisms of energy absorption with adiposity and hypothalamic neuropeptide gene expression.

  2017cites this paper
• Intratumoural production of TNFα by bacteria mediates cancer therapy

  2017cites this paper
• The ANXA1 released from intestinal epithelial cells alleviate DSS-induced colitis by improving NKG2A expression of Natural Killer cells.

  2016cites this paper
• The use of optical imaging to assess the potential for embryo-fetal exposure to an exogenous material after intravaginal administration.

  2014cites this paper
• Epithelial Interactions and Mucosal Homeostasis − Leukocyte

  2014cites this paper
• New Researches and Application Progress of Commonly Used Optical Molecular Imaging Technology

  2014cites this paper
• Leukocyte–Epithelial Interactions and Mucosal Homeostasis

  2014cites this paper
• Effective treatment of mouse experimental colitis by alpha 2 integrin antibody: comparison with alpha 4 antibody and conventional therapy

  2013cites this paper
• Bcl-3 deficiency protects against DSS-induced colitis in the mouse 1

  2013cites this paper
• Bcl‐3 deficiency protects against dextran‐sodium sulphate‐induced colitis in the mouse

  2013cites this paper
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  2013cites this paper
• Animal Models of Inflammatory Bowel Disease for Drug Discovery

  2013cites this paper
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  2013cites this paper
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  2012cites this paper
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  2011cites this paper