Toll‐like receptors signaling network in pre‐eclampsia: An updated review

Toll‐like receptors (TLRs) are innate immune cells receptors. They are expressed on leukocytes, epithelial cells, and more particularly on placental immune cells and chorion trophoblast. Upregulation of innate immune response occurs during normal pregnancy, but its excessive activity is involved in the pathology of pregnancy complications including pregnancy‐induced hypertension and pre‐eclampsia (PE). The recent studies about the overmuch inflammatory responses and aberrant placentation are associated with increased expression of TLRs in PE patients. This review has tried to focus on the relationship between some activities of TLRs and the risk of preeclampsia development.

• Publication year

  2018

• Venue

  Journal of Cellular Physiology

• Publication date

  2018-09-16

• Fields of study

  Medicine

• Identifiers
  DOI 10.1002/jcp.27189PMID 30221394
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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