Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Nature Genetics

• Publication date

  2010-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/ng.638PMID 20676096
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A unified approach to genotype imputation and haplotype-phase inference for large data sets of trios and unrelated individuals.

  2009cited by this paper
• Allelic imbalances and homozygous deletion on 8p23.2 for stepwise progression of hepatocarcinogenesis

  2009cited by this paper
• catmap: Case-control And TDT Meta-Analysis Package

  2008cited by this paper
• The quest for the 1p36 tumor suppressor.

  2008cited by this paper
• Hepatocellular carcinoma and the ubiquitin-proteasome system.

  2008cited by this paper
• Fine-needle aspiration of thyroid nodules: proteomic analysis to identify cancer biomarkers.

  2008cited by this paper
• KIF1Bβ Functions as a Haploinsufficient Tumor Suppressor Gene Mapped to Chromosome 1p36.2 by Inducing Apoptotic Cell Death*

  2008cited by this paper
• Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis

  2008cited by this paper
• The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.

  2008cited by this paper
• Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits

  2008cited by this paper
• A germline mutation of the KIF1Bβ gene on 1p36 in a family with neural and nonneural tumors

  2008cited by this paper
• U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.

  2008cited by this paper
• PGA: power calculator for case-control genetic association analyses

  2008cited by this paper
• U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of ΔNp63α

  2008cited by this paper
• Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

  2007cited by this paper
• Estrogen receptor alpha polymorphisms associated with susceptibility to hepatocellular carcinoma in hepatitis B virus carriers.

  2006cited by this paper
• Estrogen Receptor α Polymorphisms Associated With Susceptibility to Hepatocellular Carcinoma in Hepatitis B Virus Carriers

  2006cited by this paper
• SNPStats: a web tool for the analysis of association studies

  2006cited by this paper
• Ubiquitin and ubiquitin-like proteins in cancer pathogenesis

  2006cited by this paper
• Epidemiology of hepatocellular carcinoma.

  2005cited by this paper
• Integrating case-control and TDT studies.

  2005cited by this paper
• Single Nucleotide Polymorphisms Associated with Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Virus Infection

  2005cited by this paper
• Epidemiology and natural history of hepatocellular carcinoma.

  2005cited by this paper
• Integrating Case‐control and TDT Studies

  2005cited by this paper
• Screening for gene mutations in a 500 kb neuroblastoma tumor suppressor candidate region in chromosome 1p; mutation and stage-specific expression in UBE4B/UFD2

  2003cited by this paper
• Increased activity of glycerol 3-phosphate dehydrogenase and other lipogenic enzymes in human bladder cancer.

  2003cited by this paper
• Interaction of hepatitis B virus, chemical carcinogen, and genetic susceptibility: Multistage hepatocarcinogenesis with multifactorial etiology

  2002cited by this paper
• Genome-wide analyses on loss of heterozygosity in hepatocellular carcinoma in Southern China.

  2001cited by this paper
• Genomic structure and mutational analysis of the human KIF1B gene which is homozygously deleted in neuroblastoma at chromosome 1p36.2

  2001cited by this paper
• Familial risk of hepatocellular carcinoma among chronic hepatitis B carriers and their relatives.

  2000cited by this paper
• Sporadic and familial pheochromocytomas are associated with loss of at least two discrete intervals on chromosome 1p.

  2000cited by this paper
• A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

  1999cited by this paper
• Prospective study of hepatocellular carcinoma and liver cirrhosis in asymptomatic chronic hepatitis B virus carriers.

  1997cited by this paper
• Epidemiological characteristics and risk factors of hepatocellular carcinoma

  1997cited by this paper
• Genetics of coeliac disease.

  1996cited by this paper
• Epidemiology of hepatocellular carcinoma.

  1995cited by this paper
• KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria.

  1994cited by this paper
• [Loss of heterozygosity in hepatocellular carcinoma].

  1993cited by this paper
• The pentose phosphate pathway of glucose metabolism. Measurement of the non-oxidative reactions of the cycle.

  1968cited by this paper

• GWAS Study Identifies 3-SNP Risk Variants of PNPLA3/SAMM50 Linked to HCC Development in Individuals with Non-viral Liver Diseases

  2025cites this paper
• RBP7 knockdown inhibits proliferation of human hepatocellular carcinoma and activates the p38 MAPK pathway

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• Public health strategies for hepatocellular carcinoma: from risk factors to prevention and control

  2025cites this paper
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  2025cites this paper
• Integrated functional genomics-identified LYRM4 promotes fumarate accumulation and hepatocellular carcinoma progression.

  2025cites this paper
• Integrated functional genomics-identified DEAF1 in oxidative stress and hepatocellular carcinoma development.

  2025cites this paper
• Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

  2025cites this paper
• Correlation of IL-10 and IL18 with the development of liver cirrhosis associated with hepatitis B virus infection: A systematic review.

  2024cites this paper
• The role of kinesin family members in hepatobiliary carcinomas: from bench to bedside

  2024cites this paper
• Emerging and Clinically Accepted Biomarkers for Hepatocellular Carcinoma

  2024cites this paper
• NRDE2 deficiency impairs homologous recombination repair and sensitizes hepatocellular carcinoma to PARP inhibitors

  2024cites this paper
• Novel genetic variants in the NLRP3 inflammasome-related PANX1 and APP genes predict survival of patients with hepatitis B virus-related hepatocellular carcinoma

  2024cites this paper
• Disease modifiers and novel markers in hepatitis B virus-related hepatocellular carcinoma

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• Genome-wide functional integration identified MAZ-controlled RPS14 dysregulation in hepatocellular carcinoma

  2024cites this paper
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  2024cites this paper
• Gene variations related to the hepatocellular carcinoma: results from a field synopsis and Bayesian revaluation.

  2023cites this paper
• Possible biological mechanisms of entecavir versus tenofovir disoproxil fumarate on reducing the risk of hepatocellular carcinoma

  2023cites this paper
• TBX5 Variants are Associated with Susceptibility to and the Incidence of Liver Cirrhosis and Hepatocellular Carcinoma in the Chinese Population: A Multicenter and Follow-Up Study

  2023cites this paper
• Molecular profiling in the management of hepatocellular carcinoma

  2023cites this paper
• Germline Genetic Associations for Hepatobiliary Cancers

  2023cites this paper
• Potentially functional genetic variants in ferroptosis‐related CREB3 and GALNT14 genes predict survival of hepatitis B virus‐related hepatocellular carcinoma

  2023cites this paper
• Syringaresinol promotes the recovery of spinal cord injury by inhibiting neuron apoptosis via activating the ubiquitination factor E4B/AKT Serine/Threonine kinase signal pathway.

  2023cites this paper
• A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy

  2023cites this paper
• Outer dynein arm docking complex subunit 2 polymorphism rs7893462 modulates hepatocellular carcinoma susceptibility and can serve as an overall survival biomarker for hepatitis B virus-related hepatocellular carcinoma after hepatectomy: a cohort study with a long-term follow-up

  2023cites this paper
• Genetic Susceptibility to Hepatocellular Carcinoma in Patients with Chronic Hepatitis Virus Infection

  2023cites this paper
• An enhancer variant at 16q22.1 predisposes to hepatocellular carcinoma via regulating PRMT7 expression

  2022cites this paper
• The association of lncRNA SNPs and SNPs‐environment interactions based on GWAS with HBV‐related HCC risk and progression

  2021cites this paper
• Cancer Microbiology.

  2021cites this paper
• Integrative Functional Genomics Implicated the Key T-/B-Cell Deficiency Regulator RAG1 in Transarterial Chemoembolization of Hepatocellular Carcinoma

  2021cites this paper
• Surveillance for hepatocellular carcinoma in chronic viral hepatitis: Is it time to personalize it?

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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Chronic Hepatitis B

  2021cites this paper
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  2020cites this paper
• Impact of deep sequencing on hepatocellular carcinoma utilizing high-throughput technology

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Knowledge-based analyses reveal new candidate genes associated with risk of hepatitis B virus related hepatocellular carcinoma

  2020cites this paper
• Mutations and Genomic Alterations in Liver Cancer

  2020cites this paper
• Impact of deep sequencing on hepatocellular carcinoma utilizing high-throughput technology

  2020cites this paper
• A comprehensive evaluation of single nucleotide polymorphisms associated with hepatocellular carcinoma risk in Asian populations: A systematic review and network meta-analysis.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Omics‐derived hepatocellular carcinoma risk biomarkers for precision care of chronic liver diseases

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2019cites this paper
• A 17‐Beta‐Hydroxysteroid Dehydrogenase 13 Variant Protects From Hepatocellular Carcinoma Development in Alcoholic Liver Disease

  2019cites this paper
• Hepatocellular Carcinoma Risk Stratification by Genetic Profiling in Patients with Cirrhosis

  2019cites this paper
• The ATG16L1 Gene Variant rs2241880 (p.T300A) Is Associated With Susceptibility to HCC In Patients with Cirrhosis

  2019cites this paper
• Knowledge-based genetic association study of hepatitis B virus related hepatocellular carcinoma

  2019cites this paper
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  2019cites this paper
• Risk Factors of Hepatocellular Carcinoma for Precision Personalized Care

  2019cites this paper
• Molecular prognosis in liver cirrhosis

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  2019cites this paper
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  2019cites this paper
• Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53

  2019cites this paper
• Host Genetic Characters of Acute Exacerbation of Chronic Hepatitis B (AECHB)

  2019cites this paper
• Association between KIF1B rs17401966 genetic polymorphism and hepatocellular carcinoma susceptibility: an updated meta-analysis

  2019influential citation
• LINC01355 suppresses breast cancer growth through FOXO3-mediated transcriptional repression of CCND1

  2019cites this paper
• Genetics of Infectious Diseases

  2019cites this paper
• Genome-Wide Association Study Identifies a Genetic Prediction Model for Postoperative Survival in Patients with Hepatocellular Carcinoma

  2019cites this paper
• Genetic variation in FCER1A predicts peginterferon alfa‐2a‐induced hepatitis B surface antigen clearance in East Asian patients with chronic hepatitis B

  2019cites this paper
• Abberent expression of NOR1 protein in tumor associated macrophages contributes to the development of DEN‐induced hepatocellular carcinoma

  2018cites this paper
• Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma

  2018cites this paper
• association between KiF 1 B ( rs 17401966 ) polymorphism and hepatocellular carcinoma susceptibility : a meta-analysis

  2018cites this paper
• Global Epidemiology, Prevention, and Management of Hepatocellular Carcinoma.

  2018cites this paper
• PNPLA3 and TM6SF2 variants as risk factors of hepatocellular carcinoma across various etiologies and severity of underlying liver diseases

  2018cites this paper
• Association of MCP‐1 promoter polymorphism with susceptibility to nasopharyngeal carcinoma

  2018cites this paper
• TNIP1 Polymorphisms with the Risk of Hepatocellular Carcinoma Based on Chronic Hepatitis B Infection in Chinese Han Population

  2018cites this paper
• Microarray-based bioinformatics analysis of the prospective target gene network of key miRNAs influenced by long non-coding RNA PVT1 in HCC

  2018cites this paper
• Host genetic factors affecting hepatitis B infection outcomes: Insights from genome-wide association studies

  2018cites this paper
• Host and Viral Genetic Variation in HBV-Related Hepatocellular Carcinoma

  2018cites this paper
• UBE2L3, a susceptibility gene that plays oncogenic role in hepatitis B‐related hepatocellular carcinoma

  2018cites this paper
• Association between KIF1B (rs17401966) polymorphism and hepatocellular carcinoma susceptibility: a meta-analysis

  2018cites this paper
• Association between HLA‐DQA1/DRB1 polymorphism and development of hepatocellular carcinoma during entecavir treatment

  2018cites this paper
• Expression analysis of liver-specific circulating microRNAs in HCV-induced hepatocellular Carcinoma in Egyptian patients

  2018cites this paper
• Germline Duplication of SNORA18L5 Increases Risk for HBV-related Hepatocellular Carcinoma by Altering Localization of Ribosomal Proteins and Decreasing Levels of p53.

  2018cites this paper
• Mechanisms of Disease: The Damaged Genome in HCC

  2018cites this paper
• Genome-wide association study identifies HLA-DR variants conferring risk of HBV-related acute-on-chronic liver failure

  2017cites this paper
• Association of Mutations in Toll-like Receptor 2 Signaling Genes With Fulminant Form of Hepatitis B–Related Acute Liver Failure

  2017cites this paper
• Systematical analyses of variants in DNase I hypersensitive sites to identify hepatocellular carcinoma susceptibility loci in a Chinese population

  2017cites this paper
• Mechanism and prediction of HCC development in HBV infection.

  2017cites this paper
• Association of polymorphisms in the heparanase gene (HPSE) with hepatocellular carcinoma in Chinese populations

  2017cites this paper
• Chapter 17 – Viral Hepatitis

  2017cites this paper
• Risk factors and prevention of hepatocellular carcinoma in the era of precision medicine.

  2017cites this paper
• Genome-wide association study: new genetic insights into HBV/HCV-related hepatocellular carcinoma genomes

  2017cites this paper