Problems with the “omics”

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Trends in Analytical Chemistry

• Publication date

  2006-12-01

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1016/J.TRAC.2006.10.007
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterizing the phospholipid profiles in mammalian tissues by MALDI FTMS.

  2006cited by this paper
• Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy

  2006cited by this paper
• Pharmaco-metabonomic phenotyping and personalized drug treatment

  2006cited by this paper
• The Cinderella story of metabolic profiling: does metabolomics get to go to the functional genomics ball?

  2006cited by this paper
• Microarray: a versatile platform for high-throughput functional proteomics.

  2006cited by this paper
• A comprehensive and comparative analysis for MALDI FTMS lipid and phospholipid profiles from biological samples

  2005cited by this paper
• Regulated cell-to-cell variation in a cell-fate decision system

  2005cited by this paper
• Bridging proteomics and systems biology: What are the roads to be traveled?

  2005cited by this paper
• Capillary electrophoresis-mass spectrometry as a powerful tool in clinical diagnosis and biomarker discovery.

  2005cited by this paper
• Prediction of cancer outcome with microarrays: a multiple random validation strategy.

  2005cited by this paper
• Methodological approaches to the study of metabolism across individual tissues in man

  2005cited by this paper
• Metabolomics: Current analytical platforms and methodologies

  2005cited by this paper
• The agony and ecstasy of "OMIC" technologies in drug development.

  2005cited by this paper
• Genomics and proteomics--the way forward.

  2005cited by this paper
• Serum proteomics profiling—a young technology begins to mature

  2005cited by this paper
• Signal in noise: evaluating reported reproducibility of serum proteomic tests for ovarian cancer.

  2005cited by this paper
• Strategies for revealing lower abundance proteins in two-dimensional protein maps.

  2005cited by this paper
• Combining capillary electrophoresis with mass spectrometry for applications in proteomics

  2005cited by this paper
• Stable isotope methods for high-precision proteomics.

  2005cited by this paper
• Microdialysis--theoretical background and recent implementation in applied life-sciences.

  2005cited by this paper
• Quantitative in vivo microdialysis in pharmacokinetic studies: some reminders.

  2005cited by this paper
• Proteomics: from basic research to diagnostic application. A review of requirements & needs.

  2005cited by this paper
• Chip‐based microfluidic devices coupled with electrospray ionization‐mass spectrometry

  2005cited by this paper
• Bias as a threat to the validity of cancer molecular-marker research

  2005cited by this paper
• Protein microarrays: applications and future challenges.

  2005cited by this paper
• Symbiosis of chemometrics and metabolomics: past, present, and future

  2005cited by this paper
• Assessing the Probability That a Positive Report is False: An Approach for Molecular Epidemiology Studies

  2004cited by this paper
• Design and analysis of experiments with high throughput biological assay data.

  2004cited by this paper
• Mutational Analysis of the Tyrosine Phosphatome in Colorectal Cancers

  2004cited by this paper
• The Need for Guidelines in Publication of Peptide and Protein Identification Data

  2004cited by this paper
• The role of liquid chromatography in proteomics.

  2004cited by this paper
• Proteomics-on-a-chip: the challenge to couple lab-on-a-chip unit operations

  2004cited by this paper
• Meta-analysis of the dopamine D3 receptor gene (DRD3) Ser9Gly variant and schizophrenia

  2004cited by this paper
• Getting the Noise Out of Gene Arrays

  2004cited by this paper
• Proteomic patterns to identify ovarian cancer: 3 years on

  2004cited by this paper
• Challenges in mass spectrometry‐based proteomics

  2004cited by this paper
• A test before its time? FDA stalls distribution process of proteomic test.

  2004cited by this paper
• Screening for disease-markers and investigating drug effects by proteome profiling: can it meet expectations?

  2004cited by this paper
• Gene association studies typically wrong

  2004cited by this paper
• Detection of cancer-specific markers amid massive mass spectral data

  2003cited by this paper
• Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

  2003cited by this paper
• False discovery rate in linkage and association genome screens for complex disorders.

  2003cited by this paper
• The challenges of developing a sound proteomics strategy

  2002cited by this paper
• Molecular Biologist's Guide to Proteomics

  2002cited by this paper
• The framework of pathology: good laboratory practice by quantitative and molecular methods

  2002cited by this paper
• Cribbage

  2001cited by this paper
• Protein functions and biological contexts

  2001cited by this paper
• Integrating molecular medicine with functional proteomics: Realities and expectations

  2001cited by this paper
• Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

  2001cited by this paper
• Combining Genomics, Metabolome Analysis, and Biochemical Modelling to Understand Metabolic Networks

  2001cited by this paper
• Replication validity of genetic association studies

  2001cited by this paper
• A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

  2001cited by this paper
• Proteomics: Capacity versus utility

  2000cited by this paper
• Immunohistochemical demonstration of oestrogen and progesterone receptors: correlation of standards achieved on in house tumours with that achieved on external quality assessment material in over 150 laboratories from 26 countries

  2000cited by this paper
• Better approaches to finding the needle in a haystack: Optimizing proteome analysis through automation

  2000cited by this paper
• The dynamic range of protein expression: A challenge for proteomic research

  2000cited by this paper
• Predicting the future: a critical appraisal of cancer prognosis studies

  1999cited by this paper
• Proteomics: translating genomics into products?

  1999cited by this paper
• Microarrays: biotechnology's discovery platform for functional genomics.

  1998cited by this paper
• Proteome and proteomics: New technologies, new concepts, and new words

  1998cited by this paper
• The Future of Genetic Studies of Complex Human Diseases

  1996cited by this paper
• Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray

  1995cited by this paper
• Association between schizophrenia and homozygosity at the dopamine D3 receptor gene.

  1992cited by this paper
• For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group. Problems of Reporting Genetic Associations with Complex Outcomes

  year unknowncited by this paper

• A large, multisite investigation into the lipidomics of survival in dairy cows.

  2026cites this paper
• Advancing Non-Small-Cell Lung Cancer Management Through Multi-Omics Integration: Insights from Genomics, Metabolomics, and Radiomics

  2025cites this paper
• Trends and Pitfalls in the Progress of Network Pharmacology Research on Natural Products

  2025cites this paper
• Revolutionizing renal biopsy: the emerging role of omics and artificial intelligence in nephrology

  2025cites this paper
• Improving Omics-Based Classification: The Role of Feature Selection and Synthetic Data Generation

  2025cites this paper
• Unveiling the influence of caffeine on topiramate: metabolomic marker analysis using liquid chromatography-mass spectrometry

  2025cites this paper
• Advanced Understanding of Dietary Fiber With Omics

  2025cites this paper
• Special Issue “Current Research on Omics of Microorganisms”

  2025cites this paper
• The Current State of Proteomics and Metabolomics for Inner Ear Health and Disease

  2024cites this paper
• Finding new analgesics: Computational pharmacology faces drug discovery challenges.

  2024cites this paper
• Multi-omics data integration and drug screening of AML cancer using generative adversarial network.

  2024cites this paper
• Cyber-biological convergence: a systematic review and future outlook

  2024cites this paper
• Effect of β-Alanine Metabolite on Gut Integrity and Immunity in Commercial Broiler Chickens Infected with Eimeria maxima

  2024cites this paper
• Study design synopsis: 'Omics' terminologies-A guide for the equine clinician.

  2024cites this paper
• Nuclear Magnetic Resonance Applications in Fermented Foods and Plant-Based Beverages: Challenges and Opportunities

  2024cites this paper
• The Cantabria Cohort, a protocol for a population-based cohort in northern Spain

  2023cites this paper
• Exploratory data fusion of untargeted multimodal LC-HRMS with annotation by LCMS-TOF-ion mobility: White wine case study

  2023cites this paper
• From Microcosm to Macrocosm: The -Omics, Multiomics, and Sportomics Approaches in Exercise and Sports

  2023cites this paper
• OMICS and Other Advanced Technologies in Mycological Applications

  2023cites this paper
• Using Artificial Intelligence to Better Predict and Develop Biomarkers.

  2023cites this paper
• Skin Cancer Metabolic Profile Assessed by Different Analytical Platforms

  2023cites this paper
• Untargeted metabolomics based on nuclear magnetic resonance spectroscopy and multivariate classification techniques for identifying metabolites associated with breast cancer patients

  2022cites this paper
• Severe testing with high-dimensional omics data for enhancing biomedical scientific discovery

  2022cites this paper
• Metallophenolomics: A Novel Integrated Approach to Study Complexation of Plant Phenolics with Metal/Metalloid Ions

  2022cites this paper
• Network Pharmacology of Adaptogens in the Assessment of Their Pleiotropic Therapeutic Activity

  2022cites this paper
• The association between the pre-pregnancy vaginal microbiome and time-to-pregnancy: a Chinese pregnancy-planning cohort study

  2022cites this paper
• Are the statistical tests the best way to deal with the biomarker selection problem?

  2022cites this paper
• Using Artificial Intelligence to Better Predict and Develop Biomarkers.

  2022cites this paper
• Versatile Functional Energy Metabolism Platform Working From Research to Patient: An Integrated View of Cell Bioenergetics

  2022cites this paper
• Omics Approaches for Elucidating Abiotic Stress Responses in Plants

  2021cites this paper
• Microbial diversity and functionality of traditional fermented milk products of India: Current scenario and future perspectives

  2021cites this paper
• Shaping the next steps of research on frailty: challenges and opportunities

  2021cites this paper
• Empirically-derived synthetic populations to mitigate small sample sizes

  2020cites this paper
• Metabolomics-assisted crop improvement

  2020cites this paper
• Omics and Plant Genetic Resources: Towards Mining Potential Genes

  2020cites this paper
• Omics in traditional vegetable fermented foods and beverages

  2020cites this paper
• Analysis of Megavariate Data in Functional Omics

  2020cites this paper
• The human genome and molecular medicine

  2020cites this paper
• Comparative analyses of copy number variations between Bos taurus and Bos indicus

  2020cites this paper
• ESTUDO BIBLIOMÉTRICO SOBRE BIOINFORMÁTICA : UM LEVANTAMENTO NA BIBLIOTECA BRASILEIRA DE TESES E DISSERTAÇÕES

  2020cites this paper
• Analysis of Megavariate Data in Functional Omics q

  2020cites this paper
• Omics (Genomics, Proteomics, Metabolomics, Etc.) Tools to Study the Environmental Microbiome and Bioremediation

  2020cites this paper
• Efficient identification of multiple pathways: RNA-Seq analysis of livers from 56Fe ion irradiated mice

  2020cites this paper
• Sparse Projection Pursuit Analysis: An Alternative for Exploring Multivariate Chemical Data.

  2019cites this paper
• Machine and deep learning meet genome-scale metabolic modeling

  2019cites this paper
• Use of multivariate statistical methods for the analysis of metabolomic data

  2019cites this paper
• Rooting of eucalypt cuttings as a problem-solving oriented model in plant biology.

  2019cites this paper
• The three-legged stool of understanding metabolism: integrating metabolomics with biochemical genetics and computational modeling

  2018cites this paper
• Empirically-Derived Synthetic Populations to Overcome Small Sample Sizes

  2018cites this paper
• Next generation microbiological risk assessment-Potential of omics data for hazard characterisation.

  2018cites this paper
• Diagnostic Biomarkers: Are We Moving from Discovery to Clinical Application?

  2018cites this paper
• An Integrated Data-Driven Strategy for Safe-by-Design Nanoparticles: The FP7 MODERN Project.

  2017cites this paper
• Analytical Techniques in Lipidomics: State of the Art

  2017cites this paper
• A metabolomics investigation of in utero antiretroviral exposure to neonates

  2017cites this paper
• Chapter 34 – Biologic Markers in Clinical Trials and Clinical Care

  2017cites this paper
• Integrative Pathway Analysis Pipeline For Mirna And Mrna Data

  2017cites this paper
• Genetic Engineering and Human Mental Ecology: Interlocking Effects and Educational Considerations

  2017cites this paper
• Development of a protein-based sensor assay for rapid classification of complex biological samples

  2016cites this paper
• Emerging tools and approaches to biotechnology in the omics era

  2016cites this paper
• A metabolomics investigation of Tuberculous Meningitis in infants and children

  2016cites this paper
• Omics: A Newer Technique in Herbal Drug Standardization & Quantification

  2016cites this paper
• Determining the fitness and competitive advantage of the epidemic ExPEC clone E. coli ST131

  2015cites this paper
• Investigations into the Use of a Protein Sensor Assay for Metabolite Analysis

  2015cites this paper
• Review of validation and reporting of non-targeted fingerprinting approaches for food authentication.

  2015cites this paper
• Microwave-Assisted Sample Preparation Focusing on “Omics” Areas

  2014cites this paper
• Use of metabolomics to study water deficit stress on the medicinal plant thyme

  2014cites this paper
• Avaliação Analítica de Potenciais Biomarcadores para Câncer de Bexiga em Urina

  2014cites this paper
• An Assessment of the Relative Influences of Genetic Background, Functional Diversity at Major Regulatory Genes, and Transgenic Constructs on the Tomato Fruit Metabolome

  2014cites this paper
• Methods Applied to the In Vitro Primary Toxicology Testing of Natural Products: State of the Art, Strengths, and Limits

  2014cites this paper
• Proteomic approach to oxidative stress in Daphnia magna

  2014cites this paper
• Microfluidics for the analysis of membrane proteins: How do we get there?

  2014cites this paper
• Characterisation of metabolic profile of banana genotypes, aiming at biofortified Musa spp. cultivars.

  2014cites this paper
• KEMREP: A New Qualitative Method for the Assessment of an Analyst’s Ability to Generate a Metabolomics Data Matrix by Gas Chromatography– Mass Spectrometry

  2014cites this paper
• CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics.

  2014cites this paper
• Liquid chromatography tandem mass spectrometry study of urinary nucleosides as potential cancer markers.

  2013cites this paper
• Proteomic evaluation of genetically modified crops: current status and challenges

  2013cites this paper
• Gıda Biliminde Yeni Omik Teknolojileri

  2012cites this paper
• Visualization and Curve-Parameter Estimation Strategies for Efficient Exploration of Phenotype Microarray Kinetics

  2012cites this paper
• Aspects of experimental design for plant metabolomics experiments and guidelines for growth of plant material.

  2012cites this paper
• Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms.

  2012cites this paper
• Experimental ‘omics’ data in tree research: facing complexity

  2012influential citation
• Metabolic responses to change in disease activity during tumor necrosis factor inhibition in patients with rheumatoid arthritis.

  2012cites this paper
• Challenges for Metabolomics as a Tool in Safety Assessments

  2012cites this paper
• Metabolic Variation in Autoimmune Diseases

  2012cites this paper
• Chemical Qualitative Analysis II

  2011cites this paper
• The Relevance of Compositional and Metabolite Variability in Safety Assessments of Novel Crops

  2011cites this paper
• Analytical aspects in doping control: challenges and perspectives.

  2011cites this paper
• Evaluation of Genetically Engineered Crops Using Transcriptomic, Proteomic, and Metabolomic Profiling Techniques

  2011cites this paper
• Genomic Misconception of Transgenesis

  2011cites this paper
• Integrated multifunctional microfluidics for automated proteome analyses.

  2011cites this paper
• The Informatics (R) Evolution in Biology:: The Case of Genomics

  2011cites this paper
• Natural variability and correlations in the metabolic profile of healthy Eisenia fetida earthworms observed using ¹H NMR metabolomics.

  2011cites this paper
• Novel strategies for tracing the exposure of meat cattle to illegal growth-promoters.

  2011cites this paper
• An Algebraic Approach to Modelling the Regulation of Gene Expression

  2011cites this paper
• Are Natural Deep Eutectic Solvents the Missing Link in Understanding Cellular Metabolism and Physiology?[W]

  2011cites this paper
• Non-target Identification. Chromatography and Spectrometry

  2011cites this paper
• Estimating false discovery rate and false non-discovery rate using the empirical cumulative distribution function of p-values in ‘omics’ studies

  2011cites this paper
• Lipidomics era: accomplishments and challenges.

  2010cites this paper
• Effectiveness of strategies to increase the validity of findings from association studies: size vs. replication

  2010cites this paper
• Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

  2010cites this paper